LOCUS       NM_027911               3476 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ribonucleoprotein, PTB-binding 1 (Raver1), mRNA.
ACCESSION   NM_027911
VERSION     NM_027911.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3476)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3476)
  AUTHORS   Markiewicz-Potoczny,M., Lobanova,A., Loeb,A.M., Kirak,O.,
            Olbrich,T., Ruiz,S. and Lazzerini Denchi,E.
  TITLE     TRF2-mediated telomere protection is dispensable in pluripotent
            stem cells
  JOURNAL   Nature 589 (7840), 110-115 (2021)
   PUBMED   33239785
REFERENCE   3  (bases 1 to 3476)
  AUTHORS   Lahmann,I., Fabienke,M., Henneberg,B., Pabst,O., Vauti,F.,
            Minge,D., Illenberger,S., Jockusch,B.M., Korte,M. and Arnold,H.H.
  TITLE     The hnRNP and cytoskeletal protein raver1 contributes to synaptic
            plasticity
  JOURNAL   Exp Cell Res 314 (5), 1048-1060 (2008)
   PUBMED   18061163
  REMARK    GeneRIF: raver1 may play an important role for the regulation of
            neuronal synaptic plasticity, possibly by controlling especially
            the late LTP via posttranscriptional mechanisms.
REFERENCE   4  (bases 1 to 3476)
  AUTHORS   Zieseniss,A., Schroeder,U., Buchmeier,S., Schoenenberger,C.A., van
            den Heuvel,J., Jockusch,B.M. and Illenberger,S.
  TITLE     Raver1 is an integral component of muscle contractile elements
  JOURNAL   Cell Tissue Res 327 (3), 583-594 (2007)
   PUBMED   17096167
  REMARK    GeneRIF: In mice, raver1 might link gene expression with structural
            functions of muscle contractility during muscle differentiation.
REFERENCE   5  (bases 1 to 3476)
  AUTHORS   Kleinhenz,B., Fabienke,M., Swiniarski,S., Wittenmayer,N.,
            Kirsch,J., Jockusch,B.M., Arnold,H.H. and Illenberger,S.
  TITLE     Raver2, a new member of the hnRNP family
  JOURNAL   FEBS Lett 579 (20), 4254-4258 (2005)
   PUBMED   16051233
REFERENCE   6  (bases 1 to 3476)
  AUTHORS   Leeb,T. and Muller,M.
  TITLE     Comparative human-mouse-rat sequence analysis of the ICAM gene
            cluster on HSA 19p13.2 and a 185-kb porcine region from SSC 2q
  JOURNAL   Gene 343 (2), 239-244 (2004)
   PUBMED   15588578
REFERENCE   7  (bases 1 to 3476)
  AUTHORS   Gromak,N., Rideau,A., Southby,J., Scadden,A.D., Gooding,C.,
            Huttelmaier,S., Singer,R.H. and Smith,C.W.
  TITLE     The PTB interacting protein raver1 regulates alpha-tropomyosin
            alternative splicing
  JOURNAL   EMBO J 22 (23), 6356-6364 (2003)
   PUBMED   14633994
  REMARK    GeneRIF: PTB-mediated splicing repression involves recruitment of
            raver1 as a potent splicing co-repressor.
REFERENCE   8  (bases 1 to 3476)
  AUTHORS   Huttelmaier,S., Illenberger,S., Grosheva,I., Rudiger,M.,
            Singer,R.H. and Jockusch,B.M.
  TITLE     Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and
            microfilament attachment proteins
  JOURNAL   J Cell Biol 155 (5), 775-786 (2001)
   PUBMED   11724819
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK138596.1 and BC058271.1.
            
            On Jun 20, 2018 this sequence version replaced NM_027911.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058271.1, AK138596.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                AK138596.1         2-12
            12-3476             BC058271.1         1-3465
FEATURES             Location/Qualifiers
     source          1..3476
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 7.71 cM"
     gene            1..3476
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /note="ribonucleoprotein, PTB-binding 1"
                     /db_xref="GeneID:71766"
                     /db_xref="MGI:MGI:1919016"
     exon            1..241
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..2269
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /note="protein raver-1"
                     /codon_start=1
                     /product="ribonucleoprotein PTB-binding 1"
                     /protein_id="NP_082187.1"
                     /db_xref="CCDS:CCDS40550.1"
                     /db_xref="GeneID:71766"
                     /db_xref="MGI:MGI:1919016"
                     /translation="MAADVSVTHRPPLSPEAEAEAETPETVDRRAPEQELPPLDPEEI
                     RKRLEHTERQFRNRRKILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLN
                     GEQAEAAINTFHQSRLRERELSVQLQPTDALLCVANLPPSLTQAQFEELVRPFGSLER
                     CFLVYSERTGHSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALL
                     HSRCLCVDHLPPGFSDVDALRRALSVVYTPTFCQLACGQDGQLKGFAVLEYETAEMAE
                     AAQERADGQALGDSHLRVSFCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNLLQLL
                     NNLGPSASLQLLLNPLLHGGASGKQGLLGAPPAMPLLSGPALSTALLQLALQSQSQNQ
                     SQGQKKPGILGDSPLGTLQAGAQPSNSLLGELSAGGGLAPELPPRRGKPQPLLPPLLG
                     PSGGDREPMGLGPPATQLTPPPAPVGLRGSNHRGLPKDSGPLPTPPGVSLLGEPPKDY
                     RIPLNPYLNLHSLLPSSNLAGKETRGWGGSGRGRRPAEPPLPSPAVPGGGSGSNNGNK
                     AFQMKSRLLSPIASNRLPPEPGLPDSYGFDYPTDVGPRRLFSHPREPTLGAHGPSRHK
                     MSPPPSSFNEPRSGGGSGGPLSHFYSGSPTSYFTSGLQAGLKQSHLNKAVGSSPMGSS
                     EGLLGLGPGPNGHSHLLKTPLGGQKRSFSHLLPSPEPSPEGSYVGQHSQGLGGHYADS
                     YLKRKRIF"
     exon            242..308
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            309..778
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            779..970
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1100
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1213
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1301
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1513
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1819
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1894
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1895..2038
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2039..2122
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2123..3461
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2388..2393
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /note="hexamer: AATAGA"
     polyA_site      2410
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
                     /note="major polyA site"
     polyA_site      2670
                     /gene="Raver1"
                     /gene_synonym="1300006N24Rik"
ORIGIN      
        1 agaaggcgcc gggtttccca agatggcggc cgacgtgtcc gttactcacc ggccgccgct
       61 gagcccagag gcggaggccg aagcggaaac tcccgagacc gtcgatcgcc gggcgcccga
      121 acaagagttg ccgccgctcg atccggaaga gatccggaaa cgcctggaac acactgagcg
      181 ccagttccgt aaccgccgca agatactgat ccgaggcctc ccgggggacg tgaccaacca
      241 ggaagtacat gacctcctga gcgactacga actcaagtac tgtttcgtgg acaaatacaa
      301 agggacagct tttgtgactc tgctgaatgg ggagcaggct gaagctgcca tcaacacctt
      361 ccaccagagc cgccttcgag agcgggagct gtcagttcag ttgcagccta ccgatgctct
      421 gctgtgcgtg gccaacctac cacctagtct gacacaggca caatttgaag agctggtgcg
      481 gccctttggc agcctggagc gctgcttcct agtgtacagt gagcgcactg gccactctaa
      541 aggatatggc tttgcagagt acatgaagaa agactcagca gccagggcca agtctgactt
      601 gctgggcaag ccactgggcc cacgcacact gtatgtgcac tggacagatg ctgggcagct
      661 gacccctgca ttgttgcact ctcgatgcct ctgtgtggac cacctgccac ctggcttcag
      721 tgatgtggat gccctgcgcc gggctctgtc agtggtctat acccccacct tctgtcagct
      781 ggcatgtggc caggatgggc agctaaaggg cttcgcggtg ctggagtacg agacagcaga
      841 gatggcagag gcagcacaag aacgggcaga tggccaggcc ctgggtgaca gccacctacg
      901 tgtgtctttc tgtgccccag gtccccctgg ccgcagcatg ctagcagcac tcattgctgc
      961 ccaggccacg gctcttaatc gaggcaaggg actcctgcct gagccaaatc ttctgcagct
     1021 gttgaacaac ctgggcccat ctgcatccct ccagctgctc ctcaaccctc tgcttcatgg
     1081 gggagccagt ggcaagcagg gtctcctggg tgcgccccct gctatgccac tgctcagcgg
     1141 gcctgccctg tccactgcac tgctgcagct agccctgcag agccagagcc agaaccagag
     1201 ccagggtcag aagaagcctg ggatcctggg cgactcacct ctgggtaccc tccaggccgg
     1261 ggcccaacct tccaactccc tccttgggga gctgtctgca ggggggggcc tagccccgga
     1321 actgccgccc cgccgaggga agccacaacc cttactacca ccattgctgg gtccctctgg
     1381 gggtgaccgg gagcccatgg gtctgggtcc cccagcaacc cagctcactc cacccccagc
     1441 ccctgtgggg ctccgaggct ccaaccatag aggcctccca aaggacagtg ggcccctgcc
     1501 aacgccccct ggggtctcac tgctggggga gcccccaaag gactaccgca tccccctcaa
     1561 cccctacctg aatctacaca gcctgcttcc atccagtaac ctggcaggca aggagacccg
     1621 gggctgggga ggctctggga gaggccgccg cccagctgag ccccccttgc ctagccctgc
     1681 agttcctggt ggaggcagtg gtagcaacaa tggcaacaaa gccttccaaa tgaagtcccg
     1741 cctgctcagc cccatcgcca gcaaccgcct gccccctgag ccagggctgc ctgacagcta
     1801 tggctttgat tatcccacag atgtgggacc tagacgactc ttctcccacc ctcgggaacc
     1861 aaccttaggg gctcatggcc ccagccgaca caagatgtcc cccccaccta gcagcttcaa
     1921 tgagccccga agtggtggag gcagtggggg acccctctct catttttact ctggctcacc
     1981 cacctcctac ttcaccagtg gcctacaggc tggcctcaag cagagccacc tgaacaaggc
     2041 tgttggttcc tctccaatgg gctccagtga agggctcctg ggcctgggcc ctgggcccaa
     2101 tggtcacagt cacctgctga agaccccact gggtggccag aaacgcagtt tttcccacct
     2161 gctgccctca cctgagccca gcccagaggg cagctacgtg ggccagcact cccagggcct
     2221 cggcggccac tacgcggact cctacctgaa gcggaagagg attttctaag gggtcgacac
     2281 cagagatgct ccaagggcct gcaccaagtt gcttttgggt tttttctggt atttgtgttt
     2341 tctgggattt tatttttatt atttttttta atgtcctttc tttgggtaat agagaaatct
     2401 ctgcaaaaga ctttgctgac caaccagctg gagctcaagg aatgtggggt atctggggcc
     2461 acaccattac ctgtgggctt gctcctggag ccaaaccctg cagccttaag agagaggggc
     2521 ctgacctgct ctctttccct ccctagctcc aggcctcctc tcctgcctcg tcactcctgt
     2581 gttctggcct cttgagtgcc tttggaggtg tctctgacct gtgaggatca gagacagtcc
     2641 ccgtttttaa acttcgacaa ttgactttta tttccttttc taatttttat tattttttaa
     2701 aacaaccagg atgattatca catctactcc cccatccgtc cagaaaagcc ccaaattgat
     2761 tccttcaggg tctggcctgc ccaggctcta ttccacatgt gcaggttcca acagcttaac
     2821 cctattctct tcccagtcat ctgctgcagg tatagctgtc tcatgcccct gcctgcctat
     2881 tctggccagt accctaagcc ccaagatctc cagcccctgc cccagtatcc ttgccttctg
     2941 atgccttaaa gttgggccac aggtcctgct gggtcagagc ctcacagatg cggagctcca
     3001 aaagctccgc tcaggaccaa agagctctgg cctagggttc atcctttctc caggtgtctg
     3061 ccctgtggac agaaggctaa agccttgatc ttggcaaacc accccttttg cccaaagcct
     3121 ggatgcagag accagtattt tctgctggct tcaacagtct cccctgctgt ctgtgaaagg
     3181 tgaccattgt acccaggcca ctgggcctct accatgttct ttcaaaccca ggtcattacc
     3241 atccccaggc tggatcactg gagcaggcct cctctctgtc catgtgaggg ggacctaggg
     3301 gctctgccct tagccagctg agccaccacc agcctccctc cccaaacatg ataacccaaa
     3361 cccactccag tgggtgtatc tcaccccctc accccacccc caccccctgc atagaccttt
     3421 gctgaattaa agtttgtaag taaacggttt taaaaaaaaa aaaaaaaaaa aaaaaa
//
