LOCUS       XM_017316583            8497 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus Rap guanine nucleotide exchange factor
            (GEF) 3 (Rapgef3), transcript variant X4, mRNA.
ACCESSION   XM_017316583
VERSION     XM_017316583.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000081.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_017316583.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8497
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="15"
     gene            1..8497
                     /gene="Rapgef3"
                     /gene_synonym="2310016P22Rik; 9330170P05Rik; Epac; Epac1"
                     /note="Rap guanine nucleotide exchange factor (GEF) 3;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 6 mRNAs, 224 ESTs, 214 long SRA reads, 35
                     Proteins, and 97% coverage of the annotated genomic
                     feature by RNAseq alignments, including 44 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:223864"
                     /db_xref="MGI:MGI:2441741"
     CDS             81..2954
                     /gene="Rapgef3"
                     /gene_synonym="2310016P22Rik; 9330170P05Rik; Epac; Epac1"
                     /codon_start=1
                     /product="rap guanine nucleotide exchange factor 3 isoform
                     X4"
                     /protein_id="XP_017172072.1"
                     /db_xref="GeneID:223864"
                     /db_xref="MGI:MGI:2441741"
                     /translation="MTSPSPEDAKPGVVVGRSSSSGRWLSSFLPTSQVSWPGENHWQV
                     GPAVVESPAVGAPQVGGLPDVVPEGTLLNMVLKRMHRPRCCSYQLVFEHRRPSCIQGL
                     RWTPLTNSEDSLDFRVSLEQATTEHVHKAGKLLHRHLLATYPTLIRDRKYHLRLYRHC
                     CSGRELVDGILALGLGVHSRSQAVGICQVLLDEGALCHVKHDWTFQDRDAQFYRFPGP
                     EPEPTGTQDVEEELVEAMALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKA
                     VAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTT
                     LHEGDDFGQLALVNDAPRAATIILRENNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGK
                     VVLVLERTSQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMRPDSSAHDPTETFLS
                     DFLLTHSVFMPSTQLFTALLHHFHVEPADPAGGSEQEHSTYICNKRQQILRLVGRWVA
                     LYSPMLHSDPVATSFLQKLSDLVSRDARLSNLLREQYPERRRHHRLENGCGNVSPQTK
                     ARNAPVWLPNQEEPLPSSAGAIRVGDKVPYDICRPDHSVLTLHLPVTASVREVMAALA
                     HEDHWTKGQVLVKVNSAGDVVGLQPDARGVATSLGLNERLFVVDPQEVHELTPHPEQL
                     GPTLGSSEMLDLVSAKDLAGQLTDHDWNLFNRIHQVELIHYVLGPQHLRDVTTANLER
                     FMRRFNELQYWVATELCLCPVPGSRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNS
                     AISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALTKLSPPVIPFMPLLLKDV
                     TFIHEGNHTLVENLINFEKMRMMARAVRMLHHCRSHSTAPLSPLRSRVSHIHEDSQGS
                     RISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP"
ORIGIN      
        1 taggtgcgcc aagccagcag gacccggggc aggtcttcct gtccctcccc cggctcctgg
       61 cagggttgcc gcacctccgc atgaccagtc caagtccaga ggacgctaag ccaggggtgg
      121 tagtggggag gtccagctcc tccggccgat ggctgtcctc tttcctcccc acatcacagg
      181 tcagctggcc aggtgagaac cactggcagg tgggcccagc tgtggtggag agtccagctg
      241 tgggggcacc gcaggtggga ggtctcccgg acgtggttcc ggagggcacg ctgctcaata
      301 tggtgttgaa gagaatgcac cgtccccgct gctgctctta ccagctagtg ttcgagcacc
      361 ggcgccccag ctgcatccag ggactccgct ggacaccact taccaacagc gaggactccc
      421 tggatttcag agtgagtctg gagcaggcca ccacagagca tgtgcacaag gcagggaagc
      481 tcctgcaccg ccatctcttg gccacgtacc ctaccctcat ccgagacaga aaataccatc
      541 tgcgactata tcggcattgc tgctctggcc gggagctagt ggatgggatc ttggctctgg
      601 ggcttggggt ccactcacgg agccaagccg tgggcatctg ccaagtgttg ctggatgagg
      661 gtgccctttg tcatgtaaaa catgactgga ccttccagga ccgagatgcc caattctaca
      721 ggttccctgg accggagccc gagcctacag gaactcaaga tgtggaagag gagcttgttg
      781 aggctatggc cctcctgtcc cagcgagggc ctgatgccct actcaccgtg gcgctccgga
      841 agcccccagg tcagcgtacg gatgaagaac tggacctgat ctttgaagag ctgctgcata
      901 tcaaggcggt ggcacacctt tctaactcgg tgaagcggga actagctgct gttctgctct
      961 ttgaaccaca cagcaaggca ggaactgtgt tgttcagcca gggggacaag ggtacctcgt
     1021 ggtacattat ctggaaggga tctgtcaatg tggtgaccca tggcaagggg ctggtgacca
     1081 cgttgcacga gggagatgac tttggacagc tggctctggt gaacgacgca cctcgggcag
     1141 ccaccatcat ccttcgagaa aataactgtc actttctgcg tgtggacaag caggacttca
     1201 accgcatcat caaggatgtg gaagcaaaaa ccatgagact ggaagaacac ggcaaagtgg
     1261 tcttagttct ggagagaacc tctcagggtg ctggcccttc ccgtcccccg accccaggca
     1321 ggaaccggta tacggtcatg tctggcaccc cagagaaaat cctagaactg ctgttggagg
     1381 ctatgagacc ggattccagt gctcatgacc caacagagac gttcctcagt gacttcctgc
     1441 tgacccacag tgtcttcatg cccagcaccc agctcttcac tgccctcctg caccacttcc
     1501 acgtggagcc agcagaccct gctggaggca gcgagcagga gcacagcacc tacatctgca
     1561 acaagaggca gcagatcctg cggctagttg gccgatgggt ggccctgtat agcccgatgc
     1621 tccactcgga tcccgtggcc accagcttcc tccagaaact ctcagacctg gtgagcagag
     1681 atgcccgact tagcaacttg ctgagggaac agtatccaga gagacggcga caccacaggt
     1741 tggaaaatgg ctgtgggaac gtatctcctc agaccaaggc ccggaatgca cctgtttggc
     1801 tccctaacca ggaggaaccc ctcccaagca gcgcgggtgc catccgagtt ggggacaaag
     1861 tcccctacga catctgcaga cctgaccact cagtgctgac cctgcacctg ccggtgacgg
     1921 cctcggtgag agaagtgatg gcagctttgg cccatgagga ccactggacc aagggacagg
     1981 tgttggtgaa ggtcaattct gccggtgatg tcgttggctt gcagccagat gcccgtggtg
     2041 tggccacatc cctggggctc aacgagcggc tctttgttgt cgacccacag gaagtgcatg
     2101 agctgacccc acaccctgag cagctgggcc ccactctggg ttcttctgag atgctggacc
     2161 tagtgagcgc caaggacctg gcaggccagc tgaccgacca tgactggaac ctcttcaaca
     2221 ggatccacca ggtggagctg atccattatg tactgggccc ccagcacctg cgggatgtca
     2281 ccaccgcgaa cctggagcgc ttcatgcgcc gcttcaacga gctgcagtac tgggtggcca
     2341 cagagctctg tctctgccct gttcctggct cccgggctca gctactcagg aagttcatca
     2401 agctggcagc ccacctcaag gagcagaaga acctcaactc tttctttgcg gtcatgtttg
     2461 gcctcagcaa ctcggccatc agccggctgg cccacacctg ggagcgcctg ccccataaag
     2521 tacggaagct gtactcagcc ctggaaaggt tgctggaccc ttcctggaac caccgagtgt
     2581 accgattggc tctcaccaag ctctcccctc ctgtcatccc cttcatgccc ctgctgctca
     2641 aagacgtgac cttcatccat gaggggaacc acacactggt agagaacctc atcaactttg
     2701 agaagatgcg gatgatggcc agagcggtgc ggatgcttca ccactgccga agtcacagta
     2761 ccgcgcctct atcaccactc agaagccgag tgtcccacat ccacgaggac agccagggat
     2821 caaggatctc cacgtgttct gagcagtccc tgagcacccg gagtccagcc agcacctggg
     2881 cttatgtcca gcagctgaag gtcattgaca accagcggga actgtcccgc ctctcccggg
     2941 agctggaacc atgaggaagg actggctgga gcaggcactc tctccgagga agccagagcc
     3001 tgtgcaacca agaggtccag aggccagcca cagctgggca gggctctcca cagagcggac
     3061 tcaaggccct ggagtgggca gtgtcggggc agttgtccct gtgatgactg tcagctatgg
     3121 agatctttgt tcacggccaa ggaaaggggg gacattgagg ccatgccgtg ggtaggagag
     3181 ctgggaggta caggactctg gatcagtaga gagccctccc accgggcctt ctgcgcatct
     3241 gcacgtctgt acatctgcat gtttgcaagt ctgtacgact gtacgtgcag ctgtaccatc
     3301 cagtggtcgc caggcctcgt gcttgttttc actggggcca gtgagctcac atctgcacag
     3361 tttgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgagag agccctgggt ggggccttgc
     3421 ctgggagagg gtggagagtt ctgcttttct ctccacacat ctgagataaa cagctgggtg
     3481 taggcagggc tgttgcctag agcggtggtc tcagaggagt tgtattgttt ccataaatta
     3541 acaaagatac gtgtgtgttc taccgcctgg gtgtgtggct gggaaagctg gtggaggagg
     3601 ttgctccctg ggtacagaaa agcagacacc caccatctat ctcgggctgg gctccaggga
     3661 ggctagcggt tgctcagatg ggctccagtg ttgtcccagg cacttggggg accctcagct
     3721 ctctgaaaaa acaaaagaaa aaaaaaacca tatatatata tatatatata tatatatata
     3781 tatatatata tatatatata cacacacaca catacacaga gacggagaga gacactatga
     3841 gagtccagct gcagctaaca tcctctattt tcccctccca gcagatagct cctgatcctg
     3901 ttaggtgtca gatgctgagc aggggcctca agggggtgag agaagagact agacagaaga
     3961 ctgggaggcc taaccaattt cttcaccttg gcgatgagtg tcctgccccc ccaacgcccc
     4021 ccccccccat cccacatggg ctgtggaggt taaggccctc ttttcccggc ctcttcagtc
     4081 cctgcctgga cacagatcca ggcctagaac ctccacagag gactgctgcc ctctctactc
     4141 tccgtgctgg gagcctggca gctctagacg catctgatct gaaagctccc agcctctagg
     4201 atgaccctgt gtaaactcca ggcagcagga ctctcaggtg tctgaggagg tctgctcaca
     4261 gcagcgggcc ggaggcagct ggggcagccc tgttcttgtc ctacgggtgc agtggcaagg
     4321 ctcagacttg acacactcct ccccccctgg cctccacact gccagacact tcactctgac
     4381 gtcatgtcag cgggctccca ggagagatcc aagctgttgg caaggacttt acacctcagg
     4441 tctaatgaac ccaggtgtac caatggtctt tcttggcctt cgtttgtcca tctgtaatat
     4501 gggtatgata tctggtcgtt aagtgacaaa caagacagca ggtgttgcct ttcccagagt
     4561 gactgtccca gtcctgtgtg tgtggccccg gaggacaagc tgcatctccc agagtagagt
     4621 ctgacacagc tctcgggatg gattgactgc cagggatgac caaaccagtt ccctcgcccg
     4681 tgggcaggga gggaagatct gatggaagag accaaagctg agcaatcatg aaatcaggcc
     4741 taagcatccg tgagtcagga aagagtccct ggagcattct tgtcctccca gccattgtca
     4801 gtgtggcagt ggagaccatg cctgtcagtc tcagctctgc tcccatcatg gactcgggtg
     4861 aaaccagccc agcgatgaga cagacgttgt cctctcctcg ctggacacac ctaccttctg
     4921 atcagaagtc tgggctcctt gtgggtcttc cagcttagac aagctgcagc ttcctagcca
     4981 ttctacccca ggctggacct ctttgagcct gatgggaaag acagaagaac tctctggaca
     5041 ggcagggagc acagacttgg ggagtggatg tccgagccag gtcaccgctg gaagacagga
     5101 ggctcagagt acagagtcct cgtggcagca ggctcctggt gttcaggcag agggtgggga
     5161 acctgctcct gctccctaga agcccagggt gcgtatgggt gggtggtggt ggagaccaag
     5221 atcacaggtc tgctgagaca agggagaaag ccctagagct agcctttgaa aaacctgtca
     5281 cctaaagagg tagagcatag gcgtgtgagt gtgtgtggac aagagctgag caaccatgta
     5341 tccaggccca agtgtgtgtg tgactgtgcg tgtgtctctg cgtttgtgtg tatatgtgtg
     5401 tctgtgcatg cttgtgtgcc tctgtgtgtg tgtgttatgg atatatgtgt gtgtctgtat
     5461 gtatgtgtag gtctgtgtct gtgtatgtct ctgtgtgtgt gtatgtgtgt ctgtgcatct
     5521 gtgtgttttg tgtatgtgtg tgtgtgtgtg tgtgtgtagg tctgtgtctg tgtatgtctc
     5581 tgtgtgtatg tgtgtctgtg catctgtgtg ttttgtgtat gtgtgtgtgt gtgtgtgtgt
     5641 gtatgtcttt gtgtatgtgt gtgtatgtct ctgtgtttgt gtgtttgtgt ctgtgtgtgt
     5701 ctgtgtgtct gcatgtgtgt ctagtgagga gaagcagaac ggaaggaagt ttcattgcac
     5761 cggtctgtga ccctcccctt tcccttatgg tccctgtaag ggttatagcc acaggctgag
     5821 ctgggctagg acttcgctag gggaggtttt cctctagcag cgcacaatgc ctggtgaggg
     5881 gtagataggt tggagccagc cctctcctgt cctctaagcc attctgccca ccataggagg
     5941 attagcacaa aagtgtgacc cagctcagct gggagggagc aggctgcttt cacaggcttc
     6001 ttagctctct gtccccaaca gccctgaaac agagaccact ctgcttccca ggtggcaaaa
     6061 atgagacatt ctgacgtggc tgctattcat gagatttgtc aggataataa tcatctgaga
     6121 attgaatggt gcctctgctc tctgttcagc gggctttccc ctctaccgcc atatttttat
     6181 ctgatgacag aataggagct caggctattt ttaccttgtt tcacagtcag aggaaccgag
     6241 ctacagagat ttgcctaagg tcacctaacg gcttaatgac agggtggcct ggtgaagtga
     6301 ctgcgtaagt gtcagccatg tccctggcag gcccagtgcc acctcattgg atgtcacttt
     6361 cttctccagc agcaatagtc caggcgtgga gtcctttctt ctagcatagc atctgatttc
     6421 caaacatgaa gggagggttc tgtggatgag atcagctgcc ctgaccttcc tggatcgatt
     6481 ccctcaagcc catcagaaga ggacggtctg agaggtcgcg ttgcattcag agagtagtta
     6541 gtaaaagcct ctggctgcca atctcacctc ttgccagaag acccgaggcc cagaactgct
     6601 ctcacactga aacgcatgct cacaggactc ctcgggcctc agcttgcaga gcctcgcctc
     6661 ttgttgaggg cgcttctgct acaccacagg tgtgaactgc ctgagtttca ggcgggtatg
     6721 gttgccagtg gctggagcca actctgatgt tgcacttcat aatccatccc ttccacgtgt
     6781 ccatagacac aaaaattggt caccttatgt gtctgctaga gccccgggct tgttcacctg
     6841 ggcctgtcta cttatccccg ttgattaggg ggattcctct atcagatcgg agagctgtag
     6901 tcctcccata gcctaactgg ggcacctcag gacgaagggc ttacagccca ggcagggagt
     6961 tgtgtccctc ctgctggtga taaatggact atgctgtgaa gccacactga cttagctgct
     7021 caggaacatt ttctcttcca ggccggaggg gacatcccag aacatggata gggtaggagg
     7081 ggtggatgga acactgaggg aggagctttg aacccccacc agcacctttg gaagcaggga
     7141 gaaagcttga actccaagtg ctgggagctg tgggttctgg tggctgtgtg gatggcggct
     7201 ggccaccgtg accctcagga cagtgagtga aagacagtat acaaaaggga gcatggctcc
     7261 tgatcgagca tgcaagggca ctgagtggca gtttttatcc ccacatgggg atagataaac
     7321 tgtacctgct tctaagaggc cagagctcac cctcacatct gatcggctaa cttaaaagtg
     7381 acccagttga taagcaaagc gttcttgtcc cctgcaaaga gcttgacatc tttgctactt
     7441 cttaagtaac gtctgcctct atggatgcat gggtgggtga ctgggttgcc tagagaaagc
     7501 ggaatgtaga tggagaacct aagaacacta acgaacattt ctagggtttc cttaaagggg
     7561 acaaaccatc cgtcctaggc aatagcagta gagggtgctt ggggcaaagc ccagggtgtt
     7621 gcctggagaa atggagtgtt tcagcagctc tggggcatcc caggatttct cagagggcaa
     7681 agcagagcta ggtctcattc aggtctgcca ggaagtccta agatgtgcct gccccggcgt
     7741 cctgcaagga gagcccttgg gttggaaggc tccctgagtg cctgcctctt ctcttgggtc
     7801 ttcacaccaa gcagctgcag gtgactgcag cttgtgagcc accgcagtat taggaacgct
     7861 gacttcccac agagcaggcg aaggctgcag gctgcacctc agaaaccagg ctccagcagt
     7921 gaggtagaca gtgcgactcg ctggaggacc tctggacgga aaccaaattt tacgtttaaa
     7981 tttacattta tttttaagac atgctttgtg tctctatttt aaaccagtcc ctgtcttttt
     8041 tctctccccc ccccccacag cccacacaca cacaaggggc tttccctagt catcctattt
     8101 aaattgagcc tcttcccact tgagagaaag tctcatgtac tctaggctgg ccttgagctt
     8161 gatctgtagc taaggatcgt tttaaacgtt cttttaaaga cagatttatg tgtgcattgg
     8221 tgtgcttatt acttgtatat gtgcacactc gtgtgagttt atgtgcacag aggagctcat
     8281 ggaggtcaaa gagagcataa aatcccctgg aattggagtg agttacaggc agctgtgagt
     8341 cgccattggg tgccagcaat caagaccagg acctctgcaa gatcagtgag cactcttttt
     8401 tttttaaatt aatttccctt aatgtacatt agttatacat aacaattgga ttcattatgg
     8461 catttcattc atgtatataa aatgtatttc tatttta
//
