LOCUS       NM_001379233            3390 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript
            variant 7, mRNA.
ACCESSION   NM_001379233 XM_006538476
VERSION     NM_001379233.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3390)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3390)
  AUTHORS   Maddala,R., Nagendran,T., Lang,R.A., Morozov,A. and Rao,P.V.
  TITLE     Rap1 GTPase is required for mouse lens epithelial maintenance and
            morphogenesis
  JOURNAL   Dev Biol 406 (1), 74-91 (2015)
   PUBMED   26212757
REFERENCE   3  (bases 1 to 3390)
  AUTHORS   Bebee,T.W., Park,J.W., Sheridan,K.I., Warzecha,C.C., Cieply,B.W.,
            Rohacek,A.M., Xing,Y. and Carstens,R.P.
  TITLE     The splicing regulators Esrp1 and Esrp2 direct an epithelial
            splicing program essential for mammalian development
  JOURNAL   Elife 4, e08954 (2015)
   PUBMED   26371508
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3390)
  AUTHORS   Le Borgne,M., Chartier,N., Buchet-Poyau,K., Destaing,O.,
            Faurobert,E., Thibert,C., Rouault,J.P., Courchet,J., Negre,D.,
            Bouvard,D., Albiges-Rizo,C., Rousseaux,S., Khochbin,S.,
            Segretain,D., Crepieux,P., Guillou,F., Durand,P., Perrard,M.H. and
            Billaud,M.
  TITLE     The RNA-binding protein Mex3b regulates the spatial organization of
            the Rap1 pathway
  JOURNAL   Development 141 (10), 2096-2107 (2014)
   PUBMED   24803656
REFERENCE   5  (bases 1 to 3390)
  AUTHORS   Potla,U., Ni,J., Vadaparampil,J., Yang,G., Leventhal,J.S.,
            Campbell,K.N., Chuang,P.Y., Morozov,A., He,J.C., D'Agati,V.D.,
            Klotman,P.E. and Kaufman,L.
  TITLE     Podocyte-specific RAP1GAP expression contributes to focal segmental
            glomerulosclerosis-associated glomerular injury
  JOURNAL   J Clin Invest 124 (4), 1757-1769 (2014)
   PUBMED   24642466
  REMARK    GeneRIF: increased podocyte expression of RAP1GAP contributes
            directly to podocyte dysfunction by a mechanism that involves loss
            of RAP1-mediated activation of beta1 integrin
REFERENCE   6  (bases 1 to 3390)
  AUTHORS   Bithell,A., Alberta,J., Hornby,F., Stiles,C.D. and Williams,B.P.
  TITLE     Expression of the guanine nucleotide exchange factor, mr-gef, is
            regulated during the differentiation of specific subsets of
            telencephalic neurons
  JOURNAL   Brain Res Dev Brain Res 146 (1-2), 107-118 (2003)
   PUBMED   14643017
  REMARK    GeneRIF: Expression studies show that mr-gef is expressed by young
            neurons of the developing rodent CNS but not by progenitor cells in
            the ventricular zone (VZ).
REFERENCE   7  (bases 1 to 3390)
  AUTHORS   Morozov,A., Muzzio,I.A., Bourtchouladze,R., Van-Strien,N.,
            Lapidus,K., Yin,D., Winder,D.G., Adams,J.P., Sweatt,J.D. and
            Kandel,E.R.
  TITLE     Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK
            regulating excitability, synaptic plasticity, learning, and memory
  JOURNAL   Neuron 39 (2), 309-325 (2003)
   PUBMED   12873387
  REMARK    GeneRIF: Rap1 couples cAMP signaling to a distinct pool of
            p42/44MAPK regulating excitability, synaptic plasticity, learning,
            and memory.
REFERENCE   8  (bases 1 to 3390)
  AUTHORS   Klinger,M., Kudlacek,O., Seidel,M.G., Freissmuth,M. and Sexl,V.
  TITLE     MAP kinase stimulation by cAMP does not require RAP1 but SRC family
            kinases
  JOURNAL   J Biol Chem 277 (36), 32490-32497 (2002)
   PUBMED   12082090
  REMARK    GeneRIF: ERK activation by cAMP does not require RAP1
REFERENCE   9  (bases 1 to 3390)
  AUTHORS   Kehrer-Sawatzki,H., Wilda,M., Braun,V.M., Richter,H.P. and
            Hameister,H.
  TITLE     Mutation and expression analysis of the KRIT1 gene associated with
            cerebral cavernous malformations (CCM1)
  JOURNAL   Acta Neuropathol 104 (3), 231-240 (2002)
   PUBMED   12172908
  REMARK    GeneRIF: evidence of differential Krit1 and Rap1A expression during
            mouse ontogenesis and suggest a more widespread functional
            significance of Krit1, not restricted to vascular endothelial
            cells.
REFERENCE   10 (bases 1 to 3390)
  AUTHORS   Gould,K.A., Luongo,C., Moser,A.R., McNeley,M.K., Borenstein,N.,
            Shedlovsky,A., Dove,W.F., Hong,K., Dietrich,W.F. and Lander,E.S.
  TITLE     Genetic evaluation of candidate genes for the Mom1 modifier of
            intestinal neoplasia in mice
  JOURNAL   Genetics 144 (4), 1777-1785 (1996)
   PUBMED   8978063
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL805954.9.
            
            On Mar 28, 2020 this sequence version replaced XM_006538476.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7974084.23033.1,
                                           SRR7652917.911299.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               AL805954.9         60233-60385
            154-189             AL805954.9         62091-62126
            190-283             AL805954.9         82704-82797
            284-319             AL805954.9         88517-88552
            320-367             AL805954.9         89245-89292
            368-406             AL805954.9         90278-90316
            407-592             AL805954.9         90645-90830
            593-696             AL805954.9         94372-94475
            697-775             AL805954.9         94715-94793
            776-829             AL805954.9         95150-95203
            830-913             AL805954.9         96028-96111
            914-1014            AL805954.9         96324-96424
            1015-1144           AL805954.9         96545-96674
            1145-1300           AL805954.9         97505-97660
            1301-1372           AL805954.9         97958-98029
            1373-1459           AL805954.9         98540-98626
            1460-1597           AL805954.9         98924-99061
            1598-1729           AL805954.9         100456-100587
            1730-1807           AL805954.9         102376-102453
            1808-1917           AL805954.9         103322-103431
            1918-2031           AL805954.9         104180-104293
            2032-2155           AL805954.9         105582-105705
            2156-2258           AL805954.9         106307-106409
            2259-2362           AL805954.9         106890-106993
            2363-2403           AL805954.9         107158-107198
            2404-3390           AL805954.9         107505-108491
FEATURES             Location/Qualifiers
     source          1..3390
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 70.02 cM"
     gene            1..3390
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /note="Rap1 GTPase-activating protein"
                     /db_xref="GeneID:110351"
                     /db_xref="MGI:MGI:109338"
     exon            1..153
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..2371
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /note="isoform 5 is encoded by transcript variant 7; rap1
                     GTPase-activating protein 1"
                     /codon_start=1
                     /product="rap1 GTPase-activating protein 1 isoform 5"
                     /protein_id="NP_001366162.1"
                     /db_xref="GeneID:110351"
                     /db_xref="MGI:MGI:109338"
                     /translation="MSGRKRSFTFGAYGGVDKSFSLRQSVWRSDGQKQSFPQALNLLL
                     VDSVPSHPASPYPKNTDLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLG
                     REGPFPLILLPQFGGYWIEGTNHEISSLPETEPLQSPTTKVKLECNPTARIYRKHFLG
                     KEHFNYYSLDTALGHLVFSLKYDVIGDQEHLRLLLRTKCRTHHDVIPISCLTEFPNVV
                     QMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFS
                     TNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVST
                     KLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPD
                     GPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLE
                     ERTRAALLETLYEELHIHSQSMMGLGGDDDKMENGSGGGGFFESFKRVIRSRSQSMDA
                     MGLSNKKPNTVSTSHSGSFTPNNPDLAKAAGISLLIPGKSASRFGRRGSALGIGAVEE
                     SLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKS
                     ENSSTQSSPEMPTTKNRVESAAQRTEVLQGFSRSSSSASSFTSVVEETEGVDGDDTGL
                     ESVSSSGTPHKRDSFLYSTWLDDSVSTTSGGSSPGLTRSPHPDVGKSGDPACPEIKIQ
                     LETSEQHTPQMGC"
     exon            154..189
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            190..283
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            284..319
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            320..367
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            368..406
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            407..592
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            593..696
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            697..775
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            776..829
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            830..913
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1014
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1144
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1300
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1301..1372
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1373..1459
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1597
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1729
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1730..1807
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..1917
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1918..2031
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2032..2155
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2258
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2259..2362
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2363..2403
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2404..3390
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3365..3370
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /note="hexamer: AATAAA"
     polyA_site      3390
                     /gene="Rap1gap"
                     /gene_synonym="1300019I11Rik; 2310004O14Rik; ARPP-90; Gap;
                     Rap1ga1; Rap1GAP1"
                     /note="major polyA site"
ORIGIN      
        1 gtgccgggac ctcagctggc gggcggcccg gggcgcacac ggtccgggct ggggcggcgt
       61 tgccaaggtg acccgcgctg ggctggcgac gggcagcggc gacgatacca tgagcggccg
      121 gaagcgcagc ttcaccttcg gtgcctatgg aggggtggac aaatccttct cccttcgaca
      181 gagtgtgtgg aggagtgatg ggcagaagca gagtttccct caggcactaa acctgttact
      241 ggtggactca gttccctccc accctgcttc accctaccct aagaacacag atctgtttga
      301 gatgattgaa aagatgcagg gaagcaggat ggatgaacag cgatgctcct tcccgccacc
      361 cctcaagacg gaggaggact acattcccta cccaagtgtc catgaggttt tggggcgaga
      421 agggcccttc cccctcatcc tactgcccca gtttgggggc tactggattg aaggcaccaa
      481 ccatgaaatc agcagcctcc ctgagacaga gccgctgcag tctcccacca ccaaggtcaa
      541 gctggagtgc aaccccacag cccgaatcta ccggaagcac tttctgggca aggagcactt
      601 caattactat tcactggaca ctgctctcgg ccacctggta ttctcgctca agtatgatgt
      661 catcggggat caggagcacc tgcggctgtt gcttaggacc aagtgtcgga cccaccacga
      721 tgtcatcccc atctcctgcc tcaccgagtt ccccaacgtg gtccagatgg caaagctggt
      781 atgtgaggat gtcaatgtgg atcgattcta ccccgtgctt taccctaagg cctccaggct
      841 cattgtcacc tttgacgaac atgttatcag caataacttc aagtttggag tcatttatca
      901 gaagcttggc cagacctctg aggaagaact attcagtacc aacgaggaaa gtcctgcctt
      961 cgtggaattc ctggagtttc tgggccagaa agtgaaattg caggatttca aggggttccg
     1021 aggaggcctt gacgtgactc acgggcagac ggggaccgag tccgtatact gcaacttccg
     1081 caacaaggag atcatgtttc acgtgtccac caagctgcca tacacagaag gggacgctca
     1141 gcagttgcag cggaagcggc atatcgggaa cgacatcgtc gctgtggtct tccaggacga
     1201 aaacacgccc ttcgtgccag acatgattgc atccaacttt ctgcatgcct atgtggtggt
     1261 gcaggcagag gggggtggcc ccgatggccc cctctacaag gtctctgtca ctgctagaga
     1321 cgatgtgccc ttttttgggc ctcccctccc ggatcctgct gtgtttagga aggggcctga
     1381 gttccaggaa tttctgctga cgaagttgat caatgccgag tatgcgtgtt acaaagcaga
     1441 gaagtttgcc aaactggagg agcggacgcg tgccgccctt cttgagacgc tctacgagga
     1501 gctccatatt cacagccagt ccatgatggg cctcggcggc gacgacgaca agatggagaa
     1561 cggcagcggt gggggtggct tcttcgagtc tttcaagagg gtcatccgga gccggagtca
     1621 gtccatggat gccatgggac tgagcaacaa gaaacccaac accgtgtcaa ctagccacag
     1681 tgggagcttc acccccaaca accctgacct ggccaaggca gccggcatat cattgcttat
     1741 tcccgggaaa agcgcgagta gattcggacg ccggggcagc gccttaggca taggagctgt
     1801 ggaagagtcc ctgattgtcc ctggaaaaag ccccacaagg aagaagtctg gtccgtttgg
     1861 ctcacgccgc agcagtgcca ttggcatcga gaacatccag gaggttcagg agaagaggga
     1921 gagccctcca gctggccaga agaccccaga cagcgggcat gtctcacaag agcccaagtc
     1981 agagaactca tccactcaga gctccccaga gatgcccacg accaagaaca gagtggagtc
     2041 ggctgcccag agaacggaag tgctgcaggg cttctccaga tcttcctcca gcgccagcag
     2101 cttcaccagc gtggtggagg agacggaggg cgtagacggg gatgatacag gcctggagag
     2161 cgtgtcgtcc tcaggaactc cccataagcg ggactccttc ctctacagca catggctgga
     2221 cgacagcgtg agcaccacga gcgggggcag ctccccaggc ctcacacggt caccccaccc
     2281 agacgtcggc aagtcggggg accctgcgtg tcccgagatc aagatccaac tggaaacatc
     2341 tgagcagcac acaccccaga tgggctgcta gctgtcacct catcagcagg cgggactgag
     2401 cagaggaggc ctcagaagca caagaagatg ccgcaccaca tccaggcagc tggccctctg
     2461 ccccacagcc accccagccc ctggcgcccc tccctccaag ccctgggccc gcccatctgg
     2521 gctgtctccg cagggcggag ccatccagag ctctcagaat ggatgctgcc ggcatcaccg
     2581 cccccacccc accctcaggc tggagctctg ggtgtgggca gggactgtgg ccctggattg
     2641 ccctcacttg ggcctctgtc acaccgggtt cccctctgga gccacgggga acagggtagg
     2701 aaaaggagaa gaagcaccgt gcgcatacag cccaccgcag aagcagcagg tgcagggtgc
     2761 gcgaatgcgc aagcgccggg cagagtcccg tgcggcttct gctgtgggac gtgggccagg
     2821 caccctcatt ctctgggcat ctctgctgca agtggacaag agtatttcag agatcactga
     2881 agcctgagtc catgcacctg ccccaggagg gggccattgt cctagggacc gcctatcacg
     2941 ccgactgctt cccgaggccc cgggtgggct aaggggctgg gtctgcttca ccaatcaccc
     3001 aacctgagtc ccccagcttt accacagagc tgccaacgtc ctttcactgt ctccacacga
     3061 tggcccagta tccttggttg tggatagggt catccctggc tcctcaccca gcacccagct
     3121 taaccctgcc accccacact cctgggagca ctgggctgag ggggtctcag ctggtctgga
     3181 gtccagacct cgccatcccc tgcccaccat tgccgtggag ggggctgcca ggcatagctg
     3241 ctgtgagcca tgtccttgtg tgtgtctgtt cactcttagg agccacgccc aaggcgagac
     3301 ttccagcccc aacacccact ttggaagccc tgtggccaca tgtatgtcag taagggttgt
     3361 acaaaataaa ttctatttat cgctattgta
//
