LOCUS       NM_019930               3394 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus RAN binding protein 9 (Ranbp9), transcript variant 1,
            mRNA.
ACCESSION   NM_019930 XM_912792 XM_922486 XM_922489 XM_922491
VERSION     NM_019930.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3394)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3394)
  AUTHORS   Lv,X., Lu,X., Zhu,J. and Wang,Q.
  TITLE     Lipopolysaccharide-Induced Acute Lung Injury Is Associated with
            Increased Ran-Binding Protein in Microtubule-Organizing Center
            (RanBPM) Molecule Expression and Mitochondria-Mediated Apoptosis
            Signaling Pathway in a Mouse Model
  JOURNAL   Med Sci Monit 26, e923172 (2020)
   PUBMED   32680981
  REMARK    GeneRIF: Lipopolysaccharide-Induced Acute Lung Injury Is Associated
            with Increased Ran-Binding Protein in Microtubule-Organizing Center
            (RanBPM) Molecule Expression and Mitochondria-Mediated Apoptosis
            Signaling Pathway in a Mouse Model.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3394)
  AUTHORS   Soliman,S.H.A., Stark,A.E., Gardner,M.L., Harshman,S.W.,
            Breece,C.C., Amari,F., Orlacchio,A., Chen,M., Tessari,A.,
            Martin,J.A., Visone,R., Freitas,M.A., La Perle,K.M.D., Palmieri,D.
            and Coppola,V.
  TITLE     Tagging enhances histochemical and biochemical detection of Ran
            Binding Protein 9 in vivo and reveals its interaction with
            Nucleolin
  JOURNAL   Sci Rep 10 (1), 7138 (2020)
   PUBMED   32346083
  REMARK    GeneRIF: Tagging enhances histochemical and biochemical detection
            of Ran Binding Protein 9 in vivo and reveals its interaction with
            Nucleolin.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3394)
  AUTHORS   Yang,J., Zhang,Z., Zhang,Y., Zheng,X., Lu,Y., Tao,D., Liu,Y. and
            Ma,Y.
  TITLE     CLOCK interacts with RANBP9 and is involved in alternative splicing
            in spermatogenesis
  JOURNAL   Gene 642, 199-204 (2018)
   PUBMED   29126923
  REMARK    GeneRIF: Results showed that RANBP9 is involved in alternative
            splicing by interacting with CLOCK during murine spermatogenesis.
REFERENCE   5  (bases 1 to 3394)
  AUTHORS   Woo,J.A., Liu,T., Zhao,X., Trotter,C., Yrigoin,K., Cazzaro,S.,
            Narvaez,E., Khan,H., Witas,R., Bukhari,A., Makati,K., Wang,X.,
            Dickey,C. and Kang,D.E.
  TITLE     Enhanced tau pathology via RanBP9 and Hsp90/Hsc70 chaperone
            complexes
  JOURNAL   Hum Mol Genet 26 (20), 3973-3988 (2017)
   PUBMED   29016855
  REMARK    Erratum:[Hum Mol Genet. 2024 Apr 18;33(9):835. doi:
            10.1093/hmg/ddae026.. PMID: 38366008]
REFERENCE   6  (bases 1 to 3394)
  AUTHORS   Bai,D., Chen,H. and Huang,B.R.
  TITLE     RanBPM is a novel binding protein for p75NTR
  JOURNAL   Biochem Biophys Res Commun 309 (3), 552-557 (2003)
   PUBMED   12963025
  REMARK    GeneRIF: Using yeast two-hybrid systems, RanBPM was identified as a
            binding partner of p75(NTR).
REFERENCE   7  (bases 1 to 3394)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 3394)
  AUTHORS   Ideguchi,H., Ueda,A., Tanaka,M., Yang,J., Tsuji,T., Ohno,S.,
            Hagiwara,E., Aoki,A. and Ishigatsubo,Y.
  TITLE     Structural and functional characterization of the USP11
            deubiquitinating enzyme, which interacts with the RanGTP-associated
            protein RanBPM
  JOURNAL   Biochem J 367 (Pt 1), 87-95 (2002)
   PUBMED   12084015
  REMARK    GeneRIF: RanBPM is the enzymic substrate for USP11 and is
            deubiquitinated specifically
REFERENCE   9  (bases 1 to 3394)
  AUTHORS   Wang,D., Li,Z., Messing,E.M. and Wu,G.
  TITLE     Activation of Ras/Erk pathway by a novel MET-interacting protein
            RanBPM
  JOURNAL   J Biol Chem 277 (39), 36216-36222 (2002)
   PUBMED   12147692
REFERENCE   10 (bases 1 to 3394)
  AUTHORS   Nishitani,H., Hirose,E., Uchimura,Y., Nakamura,M., Umeda,M.,
            Nishii,K., Mori,N. and Nishimoto,T.
  TITLE     Full-sized RanBPM cDNA encodes a protein possessing a long stretch
            of proline and glutamine within the N-terminal region, comprising a
            large protein complex
  JOURNAL   Gene 272 (1-2), 25-33 (2001)
   PUBMED   11470507
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132121.3.
            
            On Apr 12, 2022 this sequence version replaced NM_019930.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14777530.621600.1,
                                           SRR14777535.546354.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-894               AC132121.3         195169-196062       c
            895-1006            AC132121.3         176469-176580       c
            1007-1059           AC132121.3         150847-150899       c
            1060-1227           AC132121.3         149571-149738       c
            1228-1250           AC132121.3         145205-145227       c
            1251-1435           AC132121.3         139787-139971       c
            1436-1548           AC132121.3         137308-137420       c
            1549-1657           AC132121.3         135968-136076       c
            1658-1848           AC132121.3         134333-134523       c
            1849-1993           AC132121.3         131082-131226       c
            1994-2115           AC132121.3         128740-128861       c
            2116-2267           AC132121.3         127168-127319       c
            2268-2379           AC132121.3         121369-121480       c
            2380-3394           AC132121.3         117432-118446       c
FEATURES             Location/Qualifiers
     source          1..3394
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 21.6 cM"
     gene            1..3394
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /note="RAN binding protein 9"
                     /db_xref="GeneID:56705"
                     /db_xref="MGI:MGI:1928741"
     exon            1..894
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     CDS             378..2510
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /note="isoform 1 is encoded by transcript variant 1; B
                     cell antigen receptor Ig beta associated protein 1;
                     ran-binding protein 9; ran-binding protein M"
                     /codon_start=1
                     /product="ran-binding protein 9 isoform 1"
                     /protein_id="NP_064314.2"
                     /db_xref="CCDS:CCDS49252.1"
                     /db_xref="GeneID:56705"
                     /db_xref="MGI:MGI:1928741"
                     /translation="MSGQPPPPPPQQQPPPPPPAAGAPGSGVALPAAAAASAGSSPAG
                     SPGGGLGAAAAALLLHPPPPPPPPPATAAPPPPASAAAPATAPPGLAVGPGPAAGVPV
                     PGLAAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRSWSPKDKFSYI
                     GLSQNNLRVHYKGHGKTPKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSA
                     QGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFY
                     TKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQHPFVFDIEDYMREWRTKIQAQ
                     IDRFPIGDREGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRI
                     QKLVLAGRMGEAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSP
                     KSQDSYPVSPRPFSSPSMSPSHGMSIHSLAPGKSSTAHFSGFESCSNGVISNKAHQSY
                     CHSKHQLSSLTVPELNSLNVSRSQQVNNFTSNDVDMETDHYSNGVGETSSNGFLNGSS
                     KHDHEMEDCDTEMEVDCSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRECGKNTA
                     NKKMLKDAFSLLAYSDPWNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAM
                     GQATQCLGLMARSGVGSCAFATVEDYLH"
     exon            895..1006
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1059
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1227
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            1228..1250
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            1251..1435
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..1548
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1657
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1848
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..1993
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            1994..2115
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            2116..2267
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            2268..2379
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     exon            2380..3394
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3229..3234
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /note="hexamer: TATAAA"
     polyA_site      3252
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /note="major polyA site"
     regulatory      3373..3378
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /note="hexamer: ATTAAA"
     polyA_site      3394
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /note="major polyA site"
ORIGIN      
        1 gcccgcccgc tcgctcgccc gccgggaaac agccgcgaga gcagcggccg ccgcggccgc
       61 tcgcacctcc tcgcagtctc tcttccccgc ttcaccgcgt cgcccagggc cgcgcgccct
      121 tccgcccgct cccctcgctg tcccaccgca tcgctcccgg tcgcgtgccc gccagcgcct
      181 ggccaacgct ccctcgcgcc cgcccgcggt cggtctcctc aaccgccgcg ctccgccggg
      241 ccgcgcggcc cgccgcctgc ttccggggcg ggcggactct gggcgcctgg tgccggcggc
      301 cgcagcgaca gcgcccccgg gaagcgcagg aggaagcagg gacgagtgga ggtgccgcag
      361 gctgagtcgc ggccgggatg tccgggcagc cgccgccacc gccgccgcaa cagcagccgc
      421 cgccgccgcc gcccgccgcc ggggccccgg gctccggagt cgccctgccc gcggccgcgg
      481 ccgccagcgc cggctcctcc ccggccggct cgcccggtgg aggcttgggg gccgcagcgg
      541 ccgccctgct gctccacccg ccgccgccgc cgccgcctcc cccggccacc gccgcgccgc
      601 cgccccccgc ctcggcggcc gcccccgcca ccgcgccgcc cggcctggcg gtgggccccg
      661 gcccggccgc aggcgtcccg gtcccgggcc tggcggcggg cagcagcgcc gctgcccctt
      721 tcccgcacgg cgactcggcc ctcaacgagc aggagaagga gctgcagagg cggctgaagc
      781 gcctctaccc ggctgtggat gagcaggaga cgccgctgcc ccggtcctgg agcccgaagg
      841 acaagttcag ctacatcggc ctctcgcaga acaacctgcg ggtgcactac aaaggtcatg
      901 gtaaaacccc caaagatgca gcatctgttc gagccacgca tccaatacca gcggcctgtg
      961 ggatttatta ttttgaagta aaaattgtca gtaagggaag agatggctac atgggaattg
     1021 gtctttctgc tcaaggtgtg aacatgaata gactaccagg ttgggataaa cattcatatg
     1081 gttaccatgg ggatgatgga cattcatttt gttcttctgg aactggacaa ccgtatggac
     1141 caacttttac aactggtgat gtcattggct gttgtgttaa tcttatcaac aatacctgct
     1201 tttacacgaa gaatggacat agtttaggta ttgctttcac cgacttaccg ccaaatttgt
     1261 atcctactgt ggggcttcag acaccaggag aagtggttga tgccaacttt gggcaacatc
     1321 cttttgtgtt tgatatagaa gactacatgc gagaatggag aaccaaaata caggcccaga
     1381 tagaccgctt tcctatcggg gatcgagaag gagaatggca gaccatgatc caaaaaatgg
     1441 tttcatctta tttagtccac catgggtact gtgccacagc agaggccttt gccagatcta
     1501 cagaccagac tgttctagaa gaattagctt ccattaagaa tagacaaaga attcagaagt
     1561 tggtgttagc aggacgaatg ggagaagcca ttgaaacaac acaacagtta tacccaagtt
     1621 tacttgaaag aaatcccaat ctccttttca cattaaaagt acgtcagttt atagaaatgg
     1681 tgaatggtac agacagtgaa gtgcggtgtt tgggaggccg aagtccaaaa tctcaagaca
     1741 gttatcccgt cagtcctcga ccctttagta gtccaagcat gagccccagt catggaatga
     1801 gtatccacag cttagcacca ggcaaaagca gcactgcaca tttttctggt tttgaaagtt
     1861 gtagcaatgg tgtaatatca aataaagcac accaatcata ttgccatagt aaacaccagc
     1921 tatccagctt gactgtaccg gagctaaaca gtctcaatgt atcaaggtca cagcaagtta
     1981 ataactttac cagtaatgat gtagacatgg aaacagatca ctactccaat ggagttggag
     2041 aaacttcatc caatggtttc ctaaatggta gctctaaaca tgaccacgaa atggaagatt
     2101 gtgacaccga aatggaagtt gactgcagtc agttaagacg ccagctgtgt ggaggaagtc
     2161 aggctgccat agagaggatg attcactttg gccgagagct acaagccatg agtgagcagc
     2221 tgaggagaga atgtggcaag aacacagcaa ataagaaaat gctgaaggac gcattcagct
     2281 tactagcata ttcggatcct tggaatagtc cagttggaaa tcagcttgac ccaattcaga
     2341 gagaacctgt gtgctcagct cttaacagtg caatattaga aacccacaat ctgccaaagc
     2401 aacctccact tgccctagcc atgggacagg ccacacagtg tctaggcctg atggctcggt
     2461 caggagttgg gtcctgtgca tttgccacag tggaagacta cctacattag ctatgcactt
     2521 caagagctca cactcacatt gtggcaaaca gtcaacatgg aagtagaccg gctctgctga
     2581 tttgaaattt agattttttt ttaattatgt actggggaca ggtttttgtc gctttacatt
     2641 gcttcctagt ttacagcatg atgcaaatga ttttctaact tagtgttagg agaaaatatt
     2701 ttccatcttt taacctctta gttgtctaag agttaaatat tactgaattt cagacgttca
     2761 aattgatcat cagaaatcct ttaaaacaat tacctaaaag aaaccaaaaa tcctgccttc
     2821 tttgttgggg ggagaagggg gaaggaaatg gaacaagttg tgtttgtgtt agcatgtggg
     2881 tgatgtaaac tacaaattgg gagctgttcc gacccccgct cctgtgtaag cattcaatca
     2941 gtgtaacttg caaaatgcat aaacatccga cagtttgaat taatagtgtt gatggaagaa
     3001 atcattttta atgtgtactg taaaacttga aatactcagg agctgagtga gtatgtttgt
     3061 tgctacttac aatcccaacc tgttagtccc agtagttttg ttttaacatg gtctttttca
     3121 actttgtttc ctgtttaact acagatgact tctgttgtag actcacaagt ttaactgttg
     3181 tattataaca gtattacatg tcaacagtgt ggttatgacc tttatttata taaaaaccaa
     3241 atatttagtc aatttaccgt gtcttaattt aatctttgta caccttccat ttttaagtgc
     3301 ttaaatgagt actatattgc aataaaaaat gtagcgatat taaaaaaaat gtagcgatat
     3361 aattaaccag ccattaaaaa tttacttcta caga
//
