LOCUS       NP_064314                710 aa            linear   ROD 01-MAY-2025
DEFINITION  ran-binding protein 9 isoform 1 [Mus musculus].
ACCESSION   NP_064314 XP_917885 XP_927579 XP_927582 XP_927584
VERSION     NP_064314.2
DBSOURCE    REFSEQ: accession NM_019930.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 710)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 710)
  AUTHORS   Lv,X., Lu,X., Zhu,J. and Wang,Q.
  TITLE     Lipopolysaccharide-Induced Acute Lung Injury Is Associated with
            Increased Ran-Binding Protein in Microtubule-Organizing Center
            (RanBPM) Molecule Expression and Mitochondria-Mediated Apoptosis
            Signaling Pathway in a Mouse Model
  JOURNAL   Med Sci Monit 26, e923172 (2020)
   PUBMED   32680981
  REMARK    GeneRIF: Lipopolysaccharide-Induced Acute Lung Injury Is Associated
            with Increased Ran-Binding Protein in Microtubule-Organizing Center
            (RanBPM) Molecule Expression and Mitochondria-Mediated Apoptosis
            Signaling Pathway in a Mouse Model.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 710)
  AUTHORS   Soliman,S.H.A., Stark,A.E., Gardner,M.L., Harshman,S.W.,
            Breece,C.C., Amari,F., Orlacchio,A., Chen,M., Tessari,A.,
            Martin,J.A., Visone,R., Freitas,M.A., La Perle,K.M.D., Palmieri,D.
            and Coppola,V.
  TITLE     Tagging enhances histochemical and biochemical detection of Ran
            Binding Protein 9 in vivo and reveals its interaction with
            Nucleolin
  JOURNAL   Sci Rep 10 (1), 7138 (2020)
   PUBMED   32346083
  REMARK    GeneRIF: Tagging enhances histochemical and biochemical detection
            of Ran Binding Protein 9 in vivo and reveals its interaction with
            Nucleolin.
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 710)
  AUTHORS   Yang,J., Zhang,Z., Zhang,Y., Zheng,X., Lu,Y., Tao,D., Liu,Y. and
            Ma,Y.
  TITLE     CLOCK interacts with RANBP9 and is involved in alternative splicing
            in spermatogenesis
  JOURNAL   Gene 642, 199-204 (2018)
   PUBMED   29126923
  REMARK    GeneRIF: Results showed that RANBP9 is involved in alternative
            splicing by interacting with CLOCK during murine spermatogenesis.
REFERENCE   5  (residues 1 to 710)
  AUTHORS   Woo,J.A., Liu,T., Zhao,X., Trotter,C., Yrigoin,K., Cazzaro,S.,
            Narvaez,E., Khan,H., Witas,R., Bukhari,A., Makati,K., Wang,X.,
            Dickey,C. and Kang,D.E.
  TITLE     Enhanced tau pathology via RanBP9 and Hsp90/Hsc70 chaperone
            complexes
  JOURNAL   Hum Mol Genet 26 (20), 3973-3988 (2017)
   PUBMED   29016855
  REMARK    Erratum:[Hum Mol Genet. 2024 Apr 18;33(9):835. doi:
            10.1093/hmg/ddae026. PMID: 38366008]
REFERENCE   6  (residues 1 to 710)
  AUTHORS   Bai,D., Chen,H. and Huang,B.R.
  TITLE     RanBPM is a novel binding protein for p75NTR
  JOURNAL   Biochem Biophys Res Commun 309 (3), 552-557 (2003)
   PUBMED   12963025
  REMARK    GeneRIF: Using yeast two-hybrid systems, RanBPM was identified as a
            binding partner of p75(NTR).
REFERENCE   7  (residues 1 to 710)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (residues 1 to 710)
  AUTHORS   Ideguchi,H., Ueda,A., Tanaka,M., Yang,J., Tsuji,T., Ohno,S.,
            Hagiwara,E., Aoki,A. and Ishigatsubo,Y.
  TITLE     Structural and functional characterization of the USP11
            deubiquitinating enzyme, which interacts with the RanGTP-associated
            protein RanBPM
  JOURNAL   Biochem J 367 (Pt 1), 87-95 (2002)
   PUBMED   12084015
  REMARK    GeneRIF: RanBPM is the enzymic substrate for USP11 and is
            deubiquitinated specifically
REFERENCE   9  (residues 1 to 710)
  AUTHORS   Wang,D., Li,Z., Messing,E.M. and Wu,G.
  TITLE     Activation of Ras/Erk pathway by a novel MET-interacting protein
            RanBPM
  JOURNAL   J Biol Chem 277 (39), 36216-36222 (2002)
   PUBMED   12147692
REFERENCE   10 (residues 1 to 710)
  AUTHORS   Nishitani,H., Hirose,E., Uchimura,Y., Nakamura,M., Umeda,M.,
            Nishii,K., Mori,N. and Nishimoto,T.
  TITLE     Full-sized RanBPM cDNA encodes a protein possessing a long stretch
            of proline and glutamine within the N-terminal region, comprising a
            large protein complex
  JOURNAL   Gene 272 (1-2), 25-33 (2001)
   PUBMED   11470507
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132121.3.
            
            On Nov 30, 2007 this sequence version replaced NP_064314.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14777530.621600.1,
                                           SRR14777535.546354.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..710
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 21.6 cM"
     Protein         1..710
                     /product="ran-binding protein 9 isoform 1"
                     /note="B cell antigen receptor Ig beta associated protein
                     1; ran-binding protein 9; ran-binding protein M"
                     /calculated_mol_wt=75637
     Region          171..313
                     /region_name="SPRY_RanBP9_10"
                     /note="SPRY domain in Ran binding proteins 9 and 10;
                     cd12909"
                     /db_xref="CDD:293966"
     Region          346..379
                     /region_name="LisH"
                     /note="Lissencephaly type-1-like homology motif;
                     smart00667"
                     /db_xref="CDD:128913"
     Region          385..>439
                     /region_name="CTLH"
                     /note="CTLH/CRA C-terminal to LisH motif domain;
                     pfam10607"
                     /db_xref="CDD:402305"
     Region          597..698
                     /region_name="CRA"
                     /note="CT11-RanBPM; smart00757"
                     /db_xref="CDD:214806"
     CDS             1..710
                     /gene="Ranbp9"
                     /gene_synonym="IBAP-1; Ibap1; RanBPM"
                     /coded_by="NM_019930.3:378..2510"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS49252.1"
                     /db_xref="GeneID:56705"
                     /db_xref="MGI:MGI:1928741"
ORIGIN      
        1 msgqpppppp qqqppppppa agapgsgval paaaaasags spagspgggl gaaaaalllh
       61 pppppppppa taappppasa aapatappgl avgpgpaagv pvpglaagss aaapfphgds
      121 alneqekelq rrlkrlypav deqetplprs wspkdkfsyi glsqnnlrvh ykghgktpkd
      181 aasvrathpi paacgiyyfe vkivskgrdg ymgiglsaqg vnmnrlpgwd khsygyhgdd
      241 ghsfcssgtg qpygptfttg dvigccvnli nntcfytkng hslgiaftdl ppnlyptvgl
      301 qtpgevvdan fgqhpfvfdi edymrewrtk iqaqidrfpi gdregewqtm iqkmvssylv
      361 hhgycataea farstdqtvl eelasiknrq riqklvlagr mgeaiettqq lypsllernp
      421 nllftlkvrq fiemvngtds evrclggrsp ksqdsypvsp rpfsspsmsp shgmsihsla
      481 pgksstahfs gfescsngvi snkahqsych skhqlssltv pelnslnvsr sqqvnnftsn
      541 dvdmetdhys ngvgetssng flngsskhdh emedcdteme vdcsqlrrql cggsqaaier
      601 mihfgrelqa mseqlrrecg kntankkmlk dafsllaysd pwnspvgnql dpiqrepvcs
      661 alnsaileth nlpkqpplal amgqatqclg lmarsgvgsc afatvedylh
//
