LOCUS       NM_001252466            2712 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus RAN binding protein 3 (Ranbp3), transcript variant 1,
            mRNA.
ACCESSION   NM_001252466
VERSION     NM_001252466.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2712)
  AUTHORS   Dai,F., Shen,T., Li,Z., Lin,X. and Feng,X.H.
  TITLE     PPM1A dephosphorylates RanBP3 to enable efficient nuclear export of
            Smad2 and Smad3
  JOURNAL   EMBO Rep 12 (11), 1175-1181 (2011)
   PUBMED   21960005
  REMARK    GeneRIF: Protein phosphatase PPM1A regulates the nuclear export of
            Smad2/3 through targeting nuclear exporter RanBP3.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2712)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2712)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   4  (bases 1 to 2712)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   5  (bases 1 to 2712)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT010491.8, CA318306.1, BC066005.1 and BB726920.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.301973.1,
                                           SRR7974084.13330.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-165               CT010491.8         27979-28143
            166-862             CA318306.1         1-697
            863-2707            BC066005.1         503-2347
            2708-2712           BB726920.1         444-448
FEATURES             Location/Qualifiers
     source          1..2712
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 29.45 cM"
     gene            1..2712
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /note="RAN binding protein 3"
                     /db_xref="GeneID:71810"
                     /db_xref="MGI:MGI:1919060"
     exon            1..187
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             166..1842
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ran-binding protein 3"
                     /codon_start=1
                     /product="ran-binding protein 3 isoform 1"
                     /protein_id="NP_001239395.1"
                     /db_xref="CCDS:CCDS89127.1"
                     /db_xref="GeneID:71810"
                     /db_xref="MGI:MGI:1919060"
                     /translation="MADLANEEKPAVAPSVFVFQKDKGQKSSTEHRDLPESGEEPRGE
                     AEAPCPDTGYPESIGEHALDPSAPASASTSSLPPPAPAAQPPCVRELAGRSAGSSSPE
                     AGEDSDHEDGNYCPPVKRERTSSLTHSEEKSSGFRLKPPTLIHGQAPSAGLPSQKPRE
                     QQRGVLRPAVLQAPQPKVLSQTVPSSGTNGVSMPADCTGPATSVSPENLTQRSPSESA
                     EETHTLEEKVPQKTPHGTSEEGHCEEEQAAPQAFVFGQNLRDRVKLMNENASVADVDS
                     AAHPSSETPSATNYFLQYISSSADNATHSADNSTKFVFGQNMSERVLSPPKLNEANSD
                     TSRETTHAQSGSESSSQEAAPKKESLAESAAAYTKATAWTCLLEKVEVITGEEAESNV
                     LQIQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKL
                     WAQMQMDKASEKSIRITATDAEDQGVKVFLISASSKDTGQLYAALHHRILALRSRAEQ
                     EQEAKAPPPEPGATRATEEEDSDEDAVLAPSGVTGAGTGDEGDGQAPGST"
     exon            188..243
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            244..444
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            445..481
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            482..553
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            554..619
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            620..712
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            713..840
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            841..954
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1058
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1134
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1237
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1347
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1468
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1611
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1798
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..2712
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2689..2694
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2707
                     /gene="Ranbp3"
                     /gene_synonym="2610024N24Rik"
                     /note="major polyA site"
ORIGIN      
        1 gttactgcgc aggcgcgcgg ccggagctct agcgggtgcg agcttccctc ctcctcacac
       61 cggcgctggc ttatgggatg cgcaggcgca gaactctccc agcagaaagc cctcggagcc
      121 cgggggccgg gcgcggggcc ttgtgggagg gcttaaggaa gtaaaatggc ggacctggcg
      181 aacgaagaaa agcctgccgt cgcaccgtct gtctttgtgt ttcaaaagga caaaggacag
      241 aagtcctcca cagagcacag agacttgccg gagtcgggag aggagcctcg gggggaggcc
      301 gaggcgccct gccctgatac agggtacccc gaatccattg gggagcatgc cttagaccct
      361 tccgcccctg ctagcgcttc caccagctct cttccacccc ctgctcctgc agcccagcct
      421 ccttgtgtgc gagaactggc agggagatct gctggcagct ccagtcccga agccggagaa
      481 gattctgacc atgaggatgg aaactactgc ccccctgtca agcgtgagcg gacatcctct
      541 ctaactcact cagaagagaa gagcagcggc ttccggctga agcccccaac actcatccac
      601 ggtcaggcac ccagtgcagg tctgcccagc cagaaaccca gggaacagca gcgtggtgtg
      661 ctccgtccag ctgtgctgca ggcccctcag cccaaggtgc tgtcgcagac ggttcccagc
      721 agtggcacca atggagtcag tatgccagca gactgcacgg ggccagcaac gtctgtatca
      781 ccagaaaacc tcacgcagag gagtccctct gagtctgccg aggagacaca cacactcgag
      841 gagaaggtgc ctcagaaaac cccacatggc acctcagagg aggggcactg tgaagaggag
      901 caggcggccc cacaggcctt tgtgtttgga cagaacttga gagacagagt gaagttaatg
      961 aatgagaatg ccagcgtggc agatgtagac agtgctgcac atcccagctc agaaacaccc
     1021 tctgcgacca actacttcct tcagtacatc agttccagcg cagacaacgc gacccacagt
     1081 gctgacaact ccaccaagtt tgtgtttggc cagaacatga gtgagcgcgt cttgagcccc
     1141 ccaaagctga atgaagccaa ttcagacacc agcagggaga ctacacatgc ccagtcaggt
     1201 tctgagtcgt catcccagga ggccgccccc aagaaagagt ccctggcaga gtcagccgct
     1261 gcctatacaa aggctacagc gtggacgtgt ttgctggaga aggtggaggt catcacgggg
     1321 gaggaggcag agagcaatgt gctgcagatc cagtgtaagc tgtttgtgtt cgataagacc
     1381 tcacagtcat gggtggagcg tggccgggga cttctcaggc tcaatgacat ggcgtcaacc
     1441 gacgatggca cattacagtc ccggctagtg atgcggaccc agggcagcct gcggctcatc
     1501 ctgaacacga agctgtgggc acagatgcag atggataagg ccagtgaaaa gagcatccgc
     1561 atcacagcca ccgacgctga ggaccagggt gtcaaggttt tcctgatctc ggccagctcc
     1621 aaagacacag gccaactgta tgctgcactg caccaccgca tcctggctct gcgtagccgg
     1681 gctgaacagg aacaggaggc caaggcgccc ccacctgagc caggagccac ccgggccacc
     1741 gaggaggaag acagtgatga ggatgctgtt ctggctccct ccggtgtcac gggggctggc
     1801 acaggtgatg aaggagatgg ccaggctcct gggagcacat agcggcggag ccactgcacc
     1861 aggctgctgc tttgttgtct gtctgctgcc cgtccctccc tgcaggccgc atcatggtgg
     1921 tgtctattgc cggggtggcc acaggctgga tccgagtgtc ccctctgcag cagacgggga
     1981 cgccaggatg cggcttggga ctcagacctc atcatattga tgagtagaaa gaacgttccc
     2041 ccgccctcct ccgatcgaaa tggcacattg acacttgtca cagcttcgtg gtgaccgtcc
     2101 atccctgggc agcaacaaag agaactccag gctcagcatt ctgttgagta acttgctacc
     2161 tgctcggctt tccactctgc caggtccaca tggcaggtgc ctctccttca tttctggtgg
     2221 cttggctctt gaggtcacag atgaagctac acgtgggctg agctgacttg atgctcctat
     2281 gggtggtgcc cggcccccac gggggttcac taggtttggg cctgagaaca cctgtctgga
     2341 caaaggtgat gaaaccaaga gagctcctgc cttcttgcct gcctacgtga accacctggg
     2401 tctcccttag caggtaccca gccctgaggt gactgaccac ctagggcccc tgagaggcaa
     2461 agggaacctg caaagggcct gtccccgggc agaagatgaa gcccctaccc gtggactgtg
     2521 tggttccatc tctggccagg ccacttccag ccagcaagga caccagaggc tgccttagca
     2581 gatgggtcac actgcttcca gccttagcca gccagtgaca agtgaatcca gacgtcaccc
     2641 atgtgttttg gaacatttat gtaagattga aatgtatttg agaactgcat taaaactttt
     2701 aactaaagcc cc
//
