LOCUS       NM_023146               5009 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus RAN binding protein 17 (Ranbp17), transcript variant
            1, mRNA.
ACCESSION   NM_023146
VERSION     NM_023146.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5009)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5009)
  AUTHORS   Bao,J., Wu,Q., Song,R., Jie,Z., Zheng,H., Xu,C. and Yan,W.
  TITLE     RANBP17 is localized to the XY body of spermatocytes and interacts
            with SPEM1 on the manchette of elongating spermatids
  JOURNAL   Mol Cell Endocrinol 333 (2), 134-142 (2011)
   PUBMED   21184802
  REMARK    GeneRIF: Interactions between RANBP17 and SPEM1, for the first
            time, point to a potential function of SPEM1 in the
            RANBP17-mediated nucleocytoplasmic transport.
REFERENCE   3  (bases 1 to 5009)
  AUTHORS   Koch,P., Bohlmann,I., Schafer,M., Hansen-Hagge,T.E., Kiyoi,H.,
            Wilda,M., Hameister,H., Bartram,C.R. and Janssen,J.W.
  TITLE     Identification of a novel putative Ran-binding protein and its
            close homologue
  JOURNAL   Biochem Biophys Res Commun 278 (1), 241-249 (2000)
   PUBMED   11071879
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL669814.16, BY731762.1, AK016583.1, AL683843.9 and AL772409.4.
            
            On May 2, 2018 this sequence version replaced NM_023146.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ271458.1, AK016583.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7                 AL669814.16        35277-35283         c
            8-124               BY731762.1         2-118
            125-128             AK016583.1         17-20
            129-515             AK016583.1         22-408
            516-516             AL669814.16        14822-14822         c
            517-1538            AK016583.1         410-1431
            1539-1539           AL683843.9         193406-193406       c
            1540-3596           AK016583.1         1433-3489
            3597-5009           AL772409.4         89814-91226         c
FEATURES             Location/Qualifiers
     source          1..5009
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 19.21 cM"
     gene            1..5009
                     /gene="Ranbp17"
                     /note="RAN binding protein 17"
                     /db_xref="GeneID:66011"
                     /db_xref="MGI:MGI:1929706"
     exon            1..152
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..3401
                     /gene="Ranbp17"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ran-binding protein 17"
                     /codon_start=1
                     /product="ran-binding protein 17 isoform 1"
                     /protein_id="NP_075635.1"
                     /db_xref="CCDS:CCDS24534.1"
                     /db_xref="GeneID:66011"
                     /db_xref="MGI:MGI:1929706"
                     /translation="MALHFQSLAELEVLCTHLYVGTDLTERIEAEKALLELIDSPECL
                     SKCQLLLEQGTTSYAQLLAATCLSKLVTRINPLPIEQRIDIRNYILNYVASQPKLAPF
                     VIQALIQVIAKLTKLGWFEVQKDEFVFREIIADVKKFLQGTVEHCIIGVIILCELTQE
                     MNLVDYSRPSAKHRKIATSFRDTSLKDILVLACSLLKQVLAKPLNLQDQDQQSLVMQV
                     LKLVLSCLNFDFLGSSADESADDLCTVQIPTTWRTIFLEPETLDLFFNLYHSLPPLLS
                     QLALSCLVQFASTRRSLFSSPERAKYLGNLIKGVKRILENPQGLSDPGNYHEFCRFLA
                     RLKTNYQLGELVLVKEYAEVIGLIANFTITSLQHWEFAPNSVHYLLTLWQRMVASVPF
                     VKSAEPHLLDTYAPEITKAFITSRLESVAIVVRDNLEDPLDDTATVFQQLEQLCTVSR
                     CEYEKTCTLLVQLFDQNAQNYQKLLHAAPGLAVDMAIQEGRLAWLIYLVGTVVGGRLT
                     YTSTDEHDAMDGELSCRVFQLISLMDTRLPHCTNEKIELAVLWFLDQFRKTYVGDQLQ
                     RTSKVYARMSEVLGITDDNHVLETFMTKIVTNLKYWGRCEPVISRTLQFLSDLSVGYI
                     LLKKLVKIDAVKFMLKNHTSEHFPFLGISETYNVGDFRCRTTFYTALTRLLMVDLGED
                     EDEFENFMLPLTVSFETVLQIFNNNFKQEEVKRMLIGLARDLRGIAFALNTKTSYTML
                     FDWIYPAYLPVLQRAIERWYGEPACTTPILKLLAELMQNRSQRLNFDVSSPNGILLFR
                     EASKMICTYGNQILSLGSLSKDKIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGD
                     NHFDNVLQAFVKMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFITNLEPPVLLYV
                     LTSLSEGLTTLDTVVSSSCCTSLDYMVTYLFKHIAKEGKKPLRSREAMQAGQRLLHFM
                     QQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLP
                     KQEVLGQCFRNLMEGVEQNLSVKNRDRFTQNLSVFRRDVAEALRSDGHTDLSSLDMMS
                     "
     exon            153..299
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            300..390
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            391..557
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            558..623
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            624..728
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            729..894
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            895..968
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1088
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1235
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1408
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1602
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            1603..1708
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1844
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            1845..1918
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..1999
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            2000..2063
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2172
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2276
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            2277..2365
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            2366..2473
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            2474..2556
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            2557..2771
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            2772..2910
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            2911..3077
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            3078..3176
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            3177..3304
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     exon            3305..5009
                     /gene="Ranbp17"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3547..3552
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ranbp17"
                     /note="hexamer: TATAAA"
     polyA_site      3568
                     /gene="Ranbp17"
                     /note="major polyA site"
     polyA_site      3597
                     /gene="Ranbp17"
                     /note="major polyA site"
     regulatory      4985..4990
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ranbp17"
                     /note="hexamer: ATTAAA"
     polyA_site      5005
                     /gene="Ranbp17"
                     /note="major polyA site"
ORIGIN      
        1 gggctccgag cggagcgcgc cgagcactgg gagcgagcgg cttgggggga tcccgcggcg
       61 gccgggctcg cgcggcgcct tcgctccccc tcccctcggc cctcgggccg cgcggcctgc
      121 gccgctccgg gaagatggcg ctgcactttc agagtttggc tgagttggaa gtgctgtgta
      181 ctcatctcta cgtagggacc gatctcactg aaagaataga ggctgagaaa gcactcttgg
      241 aactgattga cagcccagaa tgtctcagca agtgtcaact tttactagaa caaggaacaa
      301 catcctatgc tcagctcctt gcagcaacat gtctttcaaa acttgttacc cgaatcaatc
      361 ctttacctat tgaacagagg atagacatca gaaactacat cctgaattat gtggcgtccc
      421 aacctaagct ggcgcccttt gtcatccaag ctctgattca agtcatcgct aaactcacca
      481 agttggggtg gtttgaggtg cagaaggatg agtttgtttt ccgagaaatc attgctgatg
      541 tgaagaagtt cctccagggc acggtggaac actgcataat aggagtgata atcctttgtg
      601 aattgacaca ggaaatgaac ttggttgatt attccagacc ttcagcaaaa cataggaaaa
      661 tagctacctc attccgtgac acttctctaa aagacattct ggtgttagcg tgttctctcc
      721 tgaaacaggt gttggccaaa cctttaaatc ttcaggatca agatcaacag agtctggtaa
      781 tgcaggtctt aaagctggtc ctcagctgcc tgaactttga cttcctgggc agttcagcag
      841 acgaatctgc ggacgatctt tgcacagtgc agattccaac aacctggaga acaattttcc
      901 tagagccaga aacattggat cttttcttca atttgtatca ctcgctccca ccactgctgt
      961 ctcagttagc actttcgtgc ttagttcagt ttgcttctac aagaagatcc ttatttagca
     1021 gtcctgagcg cgccaagtac cttggtaact taattaaagg ggtgaaaagg atacttgaaa
     1081 acccccaggg tttgtctgat cctggcaatt atcatgaatt ctgtcgattt ttggctcgtt
     1141 taaagacaaa ctatcagctg ggagagttag ttttggtgaa ggagtatgcg gaagtgattg
     1201 gattaattgc caattttact attactagcc ttcagcattg ggagtttgcc cccaacagtg
     1261 ttcattactt attaactctg tggcagagga tggtagcatc cgttcctttt gtgaagtcag
     1321 ctgaacccca cttgttagac acttatgcac ctgaaatcac aaaggccttt atcacgtccc
     1381 gtttggaatc tgttgccatt gttgtgagag ataatttaga agaccctctg gatgacactg
     1441 ctaccgtgtt ccagcagctg gagcagctgt gtacagttag cagatgtgaa tatgaaaaga
     1501 cgtgtactct tcttgtacag ctatttgacc aaaatgcaca gaactatcaa aagcttctgc
     1561 atgctgctcc ggggctggct gttgacatgg cgattcaaga aggacgtctt gcatggctga
     1621 tctacttggt tggcacagtt gtaggaggga gactaacata taccagcaca gatgagcatg
     1681 atgctatgga tggagaacta tcctgccgtg tttttcagct tatatcttta atggatacca
     1741 gattacctca ctgcaccaat gagaaaatag agcttgcagt tctctggttc ctggatcagt
     1801 ttcgtaaaac atatgttggt gatcagcttc aaagaacctc aaaggtgtat gctcgtatgt
     1861 cagaagtctt aggaataaca gatgataacc atgttctgga aacattcatg acgaaaattg
     1921 ttacaaacct gaagtactgg ggaagatgtg agcctgtaat ctccaggacg cttcagttcc
     1981 tcagtgacct gtcagttggc tatatccttt taaaaaaact tgtgaaaata gatgctgtga
     2041 aattcatgct gaaaaatcac acgagtgaac acttcccgtt tcttggcatc agtgaaactt
     2101 acaatgtggg tgacttcagg tgccggacaa ccttctacac agccctcact cgccttctga
     2161 tggtagacct gggtgaagat gaggatgaat ttgagaattt tatgctgcct ctcacagtct
     2221 cttttgaaac agtgttacaa atattcaaca ataactttaa acaggaagaa gtaaagcgta
     2281 tgttgatcgg gctggcaaga gatcttcgag ggattgcctt tgcactgaac acaaagacca
     2341 gctacaccat gctgtttgac tggatatacc cagcctatct cccagttctt cagagagcta
     2401 ttgaacggtg gtatggagaa cccgcatgta ctactccaat cttaaaactc ttggcagaac
     2461 tgatgcaaaa caggtctcag cgtttgaatt ttgatgtatc ctctcctaat ggaattcttc
     2521 tcttcagaga agccagcaaa atgatttgca cctacggaaa tcagatcctg tctcttggaa
     2581 gtctctccaa agataagatt tatccaatga aactcaaggg catctccatc tgctactcag
     2641 ctctcaagtc tgcattgtgt ggaaattatg tcagctttgg cgtcttcaag ttgtatgggg
     2701 acaaccattt tgacaatgta ctccaggcct ttgtcaaaat gctgctttca gtgtctcaca
     2761 gtgacttgct gcaataccgg aagctgagcc agtcttacta tccactgctg gaatgtctca
     2821 cccaggacca catgagcttc atcaccaact tggagcctcc tgtgctcctg tacgttctca
     2881 catctctctc agagggactc accacacttg acacagtggt ctcctccagc tgctgtacaa
     2941 gtttagacta catggtcacc tatctcttca agcacatagc aaaagaaggg aagaagccac
     3001 ttcgaagcag agaggctatg caggctggtc agagactgtt acattttatg caacaaaacc
     3061 cagatgttct gcagcagatg atgtctgtcc tcatgaacac cattgtcttt gaggattgtc
     3121 ggaaccagtg gtcagtatcc aggcctctcc tggggctcat cctgctcaac gagaagtatt
     3181 tcagtgaact gagggccagt ctgataaaca gccagcctct ccccaagcag gaagtccttg
     3241 gccagtgctt caggaacttg atggaaggag tggaacagaa cctgtctgtc aagaacagag
     3301 acaggtttac ccagaacctc tccgtcttca gaagagatgt ggcagaggcc ctgcgtagcg
     3361 atggccacac tgacctaagc agcctggaca tgatgagctg acccagctcc tgagcgtggg
     3421 ctgtgcagcc tttgtcaaga gaatctggaa ggtctgggtt ccagactacg atgctggcca
     3481 gcccagaaga gtgtattttt cagaacaagc agctaaagcc ctacattttt ataagtctga
     3541 gctaattata aaaatttata atagtgcaca tacaatgtaa attcagtatt caaagcagca
     3601 catgtttcaa gtctatctgg attcccacaa tgctaaaggg tctagaaact gtattcaacc
     3661 aaagaacata gtaaaccagg ctagtgcctg tgaccacggc tgtggatttg gtgaagatgc
     3721 agccctcact tcagtgtggg ttctgggtcg agacagatgc catctgaacc tgttgaattc
     3781 aatctttaca tctggaaaat gcaatattag ggactcgggg ctgtgggcat tgacaaggag
     3841 cttgggagga agcaccataa agcctccccc agaactgcac acaggccttt ctgcctcagc
     3901 aatatctgat aaagttcaga gacagtaaca caattagatg actaacaaac aatgtttgct
     3961 ttccactggc ataaatctaa agtggttcag tctagaagaa ttagctctgc aattgctgcc
     4021 tgcagagaga tgtgtttagg actctggaag cctagttaga agttctaggt gcacaagctc
     4081 catttaactt gaaggaaagc tgagggtggc aagttgtatc tggaagcagc tctgccttct
     4141 gaccacccag cagagttcag ctgccacctt ctgccctccg ccctccctcc gccttccaca
     4201 cgcttaacca ctgttggatg tgacttcatc caaacatagg aaatgaaggc ctttacagct
     4261 tgtgacccat caaacctaag ctattaattt ggaattgcca ctgtcaggcg ggtttcctat
     4321 ctcactgcac tgactttggc gttcaggctt acaataaaca ctgcggccat aatgtctgat
     4381 cagacctgaa aggctgacct cactgttgca ggggaaaatc cacaggctct tgctgtaatc
     4441 tcatttctca gactagtgtt tcttcaaacc tttcttgatg gttgagtttt gcaacaagct
     4501 tgtcgtatga aagccagcca cctaagttca tgcccaagtg tctgtcttcc gtgtgcaaag
     4561 ggagcgtggg aaacgggggg tctggatgag agtgcctgtg gtgttgagca ggcaggtgag
     4621 cctgaaccgt actcctccca ctccgctagg gaagaggact ctcctagaga gacaaatcct
     4681 gtacttagaa acatcagctt tcaaggagct tgacaagaat tcctctttgg tttttgttta
     4741 gtttttcact tgtttagttt tggttgtctg agcctcccta cgtagcccag gctggcctgg
     4801 aactcactgt gacatttcca cagcctcctc agtgaaggtt gataggcatc ggccacaatg
     4861 cctggcttgt gtgcttgtgg gcagggtggt tgtagctgcc ctcttcccac agcactgcac
     4921 atgcttcccc gctccagcac cgtctctcac agatgcctct agtcaacagc actgcatcgt
     4981 ttgcattaaa gtgttcacaa gaaaagaac
//
