LOCUS       NM_145824               5166 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus RAN binding protein 10 (Ranbp10), mRNA.
ACCESSION   NM_145824
VERSION     NM_145824.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5166)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5166)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 5166)
  AUTHORS   Meyer,I., Kunert,S., Schwiebert,S., Hagedorn,I., Italiano,J.E. Jr.,
            Dutting,S., Nieswandt,B., Bachmann,S. and Schulze,H.
  TITLE     Altered microtubule equilibrium and impaired thrombus stability in
            mice lacking RanBP10
  JOURNAL   Blood 120 (17), 3594-3602 (2012)
   PUBMED   22936655
  REMARK    GeneRIF: RanBP10 inhibits premature microtubule polymerization of
            beta1-tubulin and plays a pivotal role in thrombus stabilization.
REFERENCE   4  (bases 1 to 5166)
  AUTHORS   Hosono,K., Noda,S., Shimizu,A., Nakanishi,N., Ohtsubo,M.,
            Shimizu,N. and Minoshima,S.
  TITLE     YPEL5 protein of the YPEL gene family is involved in the cell cycle
            progression by interacting with two distinct proteins RanBPM and
            RanBP10
  JOURNAL   Genomics 96 (2), 102-111 (2010)
   PUBMED   20580816
REFERENCE   5  (bases 1 to 5166)
  AUTHORS   Kunert,S., Meyer,I., Fleischhauer,S., Wannack,M., Fiedler,J.,
            Shivdasani,R.A. and Schulze,H.
  TITLE     The microtubule modulator RanBP10 plays a critical role in
            regulation of platelet discoid shape and degranulation
  JOURNAL   Blood 114 (27), 5532-5540 (2009)
   PUBMED   19801445
  REMARK    GeneRIF: Data suggest that RanBP10 plays an essential role in
            hemostasis and in maintaining microtubule dynamics with respect to
            both platelet shape and function.
REFERENCE   6  (bases 1 to 5166)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   7  (bases 1 to 5166)
  AUTHORS   Wang,D., Li,Z., Schoen,S.R., Messing,E.M. and Wu,G.
  TITLE     A novel MET-interacting protein shares high sequence similarity
            with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling
  JOURNAL   Biochem Biophys Res Commun 313 (2), 320-326 (2004)
   PUBMED   14684163
REFERENCE   8  (bases 1 to 5166)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 5166)
  AUTHORS   Wang,D., Li,Z., Messing,E.M. and Wu,G.
  TITLE     Activation of Ras/Erk pathway by a novel MET-interacting protein
            RanBPM
  JOURNAL   J Biol Chem 277 (39), 36216-36222 (2002)
   PUBMED   12147692
REFERENCE   10 (bases 1 to 5166)
  AUTHORS   Hemberger,M., Himmelbauer,H., Ruschmann,J., Zeitz,C. and Fundele,R.
  TITLE     cDNA subtraction cloning reveals novel genes whose temporal and
            spatial expression indicates association with trophoblast invasion
  JOURNAL   Dev Biol 222 (1), 158-169 (2000)
   PUBMED   10885754
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC152826.2.
            
            On Mar 5, 2019 this sequence version replaced NM_145824.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024698.1, AY337314.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164140, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-259               AC152826.2         6886-7144
            260-371             AC152826.2         7905-8016
            372-424             AC152826.2         28510-28562
            425-592             AC152826.2         47300-47467
            593-615             AC152826.2         51792-51814
            616-800             AC152826.2         54083-54267
            801-913             AC152826.2         58022-58134
            914-1022            AC152826.2         59451-59559
            1023-1171           AC152826.2         59659-59807
            1172-1376           AC152826.2         59981-60185
            1377-1498           AC152826.2         60935-61056
            1499-1644           AC152826.2         61500-61645
            1645-1756           AC152826.2         61888-61999
            1757-5166           AC152826.2         62377-65786
FEATURES             Location/Qualifiers
     source          1..5166
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 53.04 cM"
     gene            1..5166
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /note="RAN binding protein 10"
                     /db_xref="GeneID:74334"
                     /db_xref="MGI:MGI:1921584"
     exon            1..259
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..1887
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /codon_start=1
                     /product="ran-binding protein 10"
                     /protein_id="NP_665823.3"
                     /db_xref="CCDS:CCDS22613.1"
                     /db_xref="GeneID:74334"
                     /db_xref="MGI:MGI:1921584"
                     /translation="MAAATADPGAGNPQAGDSSGGDSGGGLPSPGEQELSRRLQRLYP
                     AVNQHETPLPRSWSPKDKYNYIGLSQGNLRVHYKGHGKNHKDAASVRATHPIPAACGI
                     YYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYG
                     PTFTTGDVIGCCVNLINGTCFYTKNGHSLGIAFTDLPANLYPTVGLQTPGEIVDANFG
                     QQPFLFDIEDYMREWRAKVQGTVHGFPISARLGEWQAVLQNMVSSYLVHHGYCSTATA
                     FARMTETPIQEEQASIKNRQKIQKLVLEGRVGEAIETTQRFYPGLLEHNPNLLFMLKC
                     RQFVEMVNGTDSEVRSLSSRSPKSQDSYPGSPSLSPRHGPSSSHIHNTGADSPSCSNG
                     VASTKNKQNHSKYPAPSSSSSSSSSSSSSSPSSVNYSESNSTDSTKSQPHSSTSNQET
                     SDSEMEMEAEHYPNGVLESVSTRIVNGAYKHDDLQTDESSMDDGHPRRQLCGGNQAAT
                     ERIILFGRELQALSEQLGREYGKNLAHTEMLQDAFSLLAYSDPWSCPVGHQLDPIQRE
                     PVCAALNSAILESQNLPKQPPLMLALGQASECLRLMARAGLGSCSFARVDDYLH"
     exon            260..371
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            372..424
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            425..592
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            593..615
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            616..800
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            801..913
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1022
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1171
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1376
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1498
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..1644
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1645..1756
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..5166
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5143..5148
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /note="hexamer: ATTAAA"
     regulatory      5148..5153
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /note="hexamer: AATACA"
     polyA_site      5162
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
     polyA_site      5166
                     /gene="Ranbp10"
                     /gene_synonym="4432417N03Rik"
                     /note="major polyA site"
ORIGIN      
        1 gacacaatag cagctccctc caagatggcg gcggcgacgg cagacccggg agctgggaac
       61 ccgcaggctg gggactcctc cggtggggac tccgggggcg ggctaccgtc acctggagag
      121 caggaactga gtcggcgcct gcagcgcttg taccctgcgg ttaatcagca cgagacgccg
      181 ctgccgcgct cctggagccc caaggacaag tacaactaca tcggcctctc ccagggaaac
      241 ctccgtgtcc attacaaagg tcatggcaaa aatcacaaag atgcagcctc tgtacgtgcc
      301 acccacccca tcccagcagc ctgtggtatt tactattttg aagtaaagat tgtcagcaaa
      361 ggaagagatg ggtacatggg aattggactc tcagcgcaag gcgttaacat gaacagactg
      421 cctggttggg acaagcattc ctatggttac catggcgatg atgggcattc cttctgctcc
      481 tctgggacag gccagcctta tggtcccaca ttcaccacag gggatgtgat cggctgttgt
      541 gtcaacctca tcaatggcac ctgcttctac accaagaatg gccacagcct tggtatcgcc
      601 ttcacagatc tcccggccaa cctctacccc actgtcggcc tacagacacc tggggagatt
      661 gtggatgcca actttgggca gcagcccttc ctgttcgaca ttgaggacta tatgcgggag
      721 tggcgtgcca aagtccaggg cactgtgcac ggctttccca taagtgcccg gcttggcgag
      781 tggcaggcgg tgctgcagaa catggtctcg tcttacctgg tgcatcatgg gtattgttcc
      841 acagccacag cttttgcccg aatgactgaa accccgattc aggaagagca ggcatccata
      901 aagaacagac aaaaaatcca gaagctggtg ctggaaggcc gggtgggtga agccattgag
      961 acaacccagc gcttctaccc tgggctgctg gaacataatc ccaacctgct cttcatgctc
     1021 aagtgtcgac agttcgtgga gatggtgaac ggcactgaca gtgaggtccg cagcctgagt
     1081 tcccgaagcc ccaagtccca ggacagctac cctggctccc ccagcctcag cccccgacat
     1141 ggccccagta gttcccatat acacaacaca ggagcagaca gtcccagctg cagcaatggc
     1201 gtcgcatcca ccaagaacaa acagaaccac agtaaatacc ccgcacccag ctcctcctcc
     1261 tcgtcctcat cctcctcgtc ctcctcttcc ccgtcctccg tcaattactc cgagtccaac
     1321 tcaacagact ctaccaagtc ccagccccac agcagtacca gtaaccagga gaccagtgat
     1381 agcgagatgg agatggaggc agagcactat cccaatggtg tgctggaaag cgtctccacg
     1441 cgcatcgtca atggggccta taagcatgac gacctgcaga cagatgagtc cagcatggac
     1501 gacgggcatc cacggaggca gctctgcggg ggcaaccagg ctgccacaga aaggatcatc
     1561 ctgtttggcc gagagctgca ggcattgagc gagcagctgg gccgggagta cggcaagaac
     1621 ttggcccaca cggagatgct gcaggatgcc tttagcctac tagcatactc agacccctgg
     1681 agctgcccag taggtcatca gcttgatccc atccagagag agcccgtgtg tgctgctctc
     1741 aacagcgcca ttttagagtc tcagaacctg ccaaagcagc ctcctttgat gctcgccctg
     1801 ggccaggcat ctgaatgtct acggctcatg gcccgagcag gcctgggatc ttgctccttt
     1861 gccagagtcg atgactactt gcactagcag accttcctgg ctggctctgg ctggccctcc
     1921 ttcagcccta gggctggagc agccctgtcc tccgtaggca tctggtacag agacctggaa
     1981 gccatgggca gagttcactc ttcctacctg gccggtccat cctccttttc tccttccctt
     2041 cctccctccc tcccttgtcc tctcctccct gtccccttcc acgtgcagcg acctgtgact
     2101 cagtattggc tggttactca tgtggtagct tctcctttaa aggagatttt gttttgagga
     2161 gaggttggtt tttttttgtt tttgatcttg tgtttttttt ttttaacttt tttttcctcc
     2221 tgactgagcc accagtgttt atctcgggag agtttgtgct gagctggtgt ctgctaactt
     2281 agtaatgaag cctatccagg ttgatgatag cttattattt tcataagtaa aaaaacaaac
     2341 aaatgagatt atatatatat atatatataa atatatatta aaaaaaaagt cacagtattt
     2401 atcgtagcac tagtggtcca gcacctcttg ggtgaggctg tccagacacc atgtgttttt
     2461 atttgagtcc aactcattaa aaaagaatca tctcttgtca cttcaatcaa gtgatttgtt
     2521 tattttaggc tccccttttg ttgagcctca ggttcagctg ctgcccagga aatatgggtt
     2581 ttggggaagg ctgtttggtg ggcaaggtca gactaagctg ttttgcagca tcccaagagg
     2641 tgtgggtctc taggccccct ataggtaaac aaaagaactg caggttcagg gattcaggga
     2701 agtgaggtgg gccaggggca cacagcaaag caagggaaca cagggtccgt agccagcatg
     2761 ctgtctacca ctctaccctg cctctcactg cctgccttgc ccctctctcc catctcaatg
     2821 cctgccttcc cttgttaaga tggccaaata attcattact ctcagttgat tgcctggaaa
     2881 ctacctgcct tcatcccaag agctgctgtg tgccaggctg ccaagaggaa gccattccca
     2941 agacagaggc ccttaaggac agggctcttt tcttcctgcc agagtcttca ccatcactgc
     3001 ccaaccctga tgggattgat gctttctgtg gagaagttgg tacctcatgg agactgattc
     3061 ttggatcact ggtcccagag tggatggaac ccttgacttc ctgatccgga tttccctaca
     3121 gcttaaggaa ggctgctccc tacagcgtgg ccccagcgac tcttaggaag gggggactcc
     3181 atgggcctta catatgtccc accagctgtt tcacaggatc ctcacagctg gcgggacaac
     3241 agcaacaaca aaacccacta tcccagggct gagatgctgc caggacatga gtaggccatc
     3301 tgtggagggg actgtctacc aaggaagagg agggtctata cagaggacac ctaggagggc
     3361 caggatttta cctgcttcac agggtgagtg aaaagcctag gcaacctctg caaagattag
     3421 ggtcaactgt ggcaaagcca caagtgagtt tccagtctcc aagtgcatct gggcagggga
     3481 agcttttgtt ctgctggtgg acacagaaat caatggcaga gctcgagatg ttctgtgccc
     3541 accagtcctc acaaggccca cagctggaca aaattgaatt agaccatctg tcagtgagga
     3601 agtagggcct tgactgagat cctccaaaat tttgctttag ggtctaatcc tacaggctac
     3661 tatgttttcc tggttcctgt cagggcctta gtttacagct cctcaggagg tcttgtccta
     3721 tgtaaaggaa atttcatcct gtccaaggct gggacaccca agctccaagc tcaggttgga
     3781 aatatcaggc tgttaacaat ggatgggcct tacatttgga aatgaaaacc agaggcattt
     3841 gcagagcagt ggaacttaga gaacctctcc accagtcctc tccttttaca gtgaaagaaa
     3901 caggtccagg aaattaagtg atttgaccaa agccacacag caaatagtgg cagaaccagg
     3961 actaactact cctgtgggtt agacaagtcc tgtcgtgacc taaagcaaaa tggcaaatga
     4021 gctttgtaag gggttaggtt ggcgtgagtt cagcagtgcc tgagcagctg gcacctttcg
     4081 tggtgtgacg ggtagggatg ggtgctgaga cgtggattgc ggagtggctg agagggcctt
     4141 ggacggcttg ggactgctgt gtgctgcacg ggattgtatg tccacctggc tcacactcag
     4201 tacccatggc cacctcccca tttaattctg tgccttatct cactgtttca gctgagtcca
     4261 agttgtttac tctgttcctc tccagagagg ctttctgtcc tagttggaca gctcactttg
     4321 gggacataag cctttgttcc acaagctgtg gggagggcca aaatcaagct gctggagcca
     4381 gtaattagtc cagtcctgct gccagaggag acctgtatgc acccccaatt ccactagccc
     4441 atttccagga atctggagtg aggagcagtt cctggaagca acttagcaaa gagctggacc
     4501 tgaccctggt gtgcaaaagg aggacctggc cgggttgggt ttgtccagtc ctgaggtagc
     4561 agcatttcct agctcacttt ccctaggagg cacagatggc agctccttgc agagcaaggg
     4621 ccaagttggc ggatgactca gagtccctct cccccaatcc cttcctctga gggtctgtgg
     4681 ctaggtgcag actgggtgca gaacatcaca aactaaagaa gtaaggactg cctggctacc
     4741 cagcaccttc ccagtcctta agcacaaaga tgaggcagag gactgttggg gctgaacgtt
     4801 cctttggttg ctcacaactc aggtatgcat gtcattcggc agctggacag caaagcccta
     4861 cttcaccacc aatcacaggc atttggacct gtggccagat ggtggcttct ggctgtccca
     4921 gtgcccacct ctttgcatcg gttccctcca ttatcaacta cagctgaaac tggcatcctc
     4981 cacagtgtgc acactggctc tgcctttgtc cttgcaagtt gatattcggc attagcatga
     5041 aacttgtggt gtgagagggt tgacagaatt ccaacacaaa catcctagta aattgtactt
     5101 gagatgaaaa gattcctgtt gtattttgac agaattattt ttattaaaat acacatccat
     5161 gagcaa
//
