LOCUS       NM_025997               1423 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus RNA guanine-7 methyltransferase activating subunit
            (Ramac), mRNA.
ACCESSION   NM_025997
VERSION     NM_025997.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Gonatopoulos-Pournatzis,T., Dunn,S., Bounds,R. and Cowling,V.H.
  TITLE     RAM/Fam103a1 is required for mRNA cap methylation
  JOURNAL   Mol Cell 44 (4), 585-596 (2011)
   PUBMED   22099306
REFERENCE   2  (bases 1 to 1423)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1423)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC130538.4 and
            AC102077.7.
            
            On Mar 21, 2007 this sequence version replaced NM_025997.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011881.1, AK081301.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               AC130538.4         165470-165573
            105-301             AC102077.7         188382-188578       c
            302-1423            AC102077.7         186615-187736       c
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 45.71 cM"
     gene            1..1423
                     /gene="Ramac"
                     /gene_synonym="2410047I02Rik; 2610204K14Rik; Fam103a1;
                     RAM; Rammet"
                     /note="RNA guanine-7 methyltransferase activating subunit"
                     /db_xref="GeneID:67148"
                     /db_xref="MGI:MGI:1914398"
     exon            1..104
                     /gene="Ramac"
                     /gene_synonym="2410047I02Rik; 2610204K14Rik; Fam103a1;
                     RAM; Rammet"
                     /inference="alignment:Splign:2.1.0"
     exon            105..301
                     /gene="Ramac"
                     /gene_synonym="2410047I02Rik; 2610204K14Rik; Fam103a1;
                     RAM; Rammet"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..491
                     /gene="Ramac"
                     /gene_synonym="2410047I02Rik; 2610204K14Rik; Fam103a1;
                     RAM; Rammet"
                     /note="protein FAM103A1; RNMT-activating mini protein;
                     family with sequence similarity 103, member A1;
                     RNMT-activating mRNA cap methylating subunit; RNMT
                     actvating mRNA cap methylating subunit; RNMT-activating
                     mRNA cap methyltransferase subunit"
                     /codon_start=1
                     /product="RNA guanine-N7 methyltransferase activating
                     subunit"
                     /protein_id="NP_080273.1"
                     /db_xref="CCDS:CCDS21406.1"
                     /db_xref="GeneID:67148"
                     /db_xref="MGI:MGI:1914398"
                     /translation="MSDTSEEIPNFEEMFASRFTKDDKEYQEYLKRPPESPPIVEEWN
                     SRAGGNQRNRGNWLQDNRQFRGRDNRRGWPSDNRSNQWHGRSWGNNNYPQQRPEPYYQ
                     QQYTQYGHNQRPPYGYY"
     exon            302..1423
                     /gene="Ramac"
                     /gene_synonym="2410047I02Rik; 2610204K14Rik; Fam103a1;
                     RAM; Rammet"
                     /inference="alignment:Splign:2.1.0"
     regulatory      778..783
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ramac"
                     /gene_synonym="2410047I02Rik; 2610204K14Rik; Fam103a1;
                     RAM; Rammet"
                     /note="hexamer: AATAAA"
     polyA_site      798
                     /gene="Ramac"
                     /gene_synonym="2410047I02Rik; 2610204K14Rik; Fam103a1;
                     RAM; Rammet"
                     /note="major polyA site"
ORIGIN      
        1 ggaagtcggg tggttgaggg attcctgagc gtttgtttac cttggagagc cgggtggggt
       61 gcggcggtgt ggacgcccga ggtctccagt gcgtcccatg aaggatctta aaaattgtac
      121 agaatttcaa aatgagtgat acttctgaag aaattccaaa ttttgaagag atgtttgcaa
      181 gcagattcac gaaagatgac aaagaatacc aggaatactt gaaacgccct cctgagtccc
      241 ctccaattgt tgaggaatgg aatagcagag ctggtggtaa ccaaagaaat agaggcaact
      301 ggctgcaaga caacagacaa tttagaggta gggataacag acgaggatgg ccaagtgaca
      361 atcggtcaaa tcagtggcat ggacggtcat ggggtaacaa caactaccca cagcagagac
      421 cagagcccta ctatcaacaa cagtacacac agtatggcca caaccagcgg cctccatatg
      481 gttactattg acagaaatgt cggcagcttt taacaaagac cttttatttt gacaacgtgc
      541 taaatgcttg tgtgtcttct gttggtcata gtttttcatt ctattttaaa gaatgggtta
      601 ttaattgatt agaacttgag acttggaaaa aagtaatctt attagaaacc tgatgattga
      661 tgggaataaa tttattaagt gaggattatt tgacttcttt tacatactgt tttgttctat
      721 gatttggtag tgttttgagt tttccttatt tggactctag ggattctgta ttacagaaat
      781 aaaaattttt aattaaaatg ctggcttttg ctgtatgaaa gaatagcatg ctcacacgtg
      841 ctcacctctg aagtgtttca gaggctagga ctgtcagtct gtgaaaacac acccacaatt
      901 acttaaagta attgaaccac agttcagttg aaaggtaaaa caggtatgtc gcttctgtgt
      961 ttgtatgtga tcatggtgtc ttgtggttta taagtgagtc agctccagaa ctgctttggt
     1021 cctatatgga agggctcatt ttctgtgcag cctcctgagg cggtggaggg tgggatggta
     1081 gcactcaaca ttttgtatat cccaagattt ttgtaaactt acaacaagga agacatggat
     1141 gtgcgctgta acacaatact catgtaaata ttgttgcatt ttgattgttt tggtattatg
     1201 tattgatttt tatgagatta ttttcatttt caaatgctta ccttcgatgc ttcctcatac
     1261 agttatagta aggctgtcac ttgcttcaga acaatcattc ttgaaatatt ttcatgataa
     1321 cagatttatt caaataaaaa aatttaaagt ccttagtata ttatgtgtgt accaagttgt
     1381 gaaagaatga ataaataaat tgcattaaaa tgtaggcaac ttt
//
