LOCUS       NP_080273                119 aa            linear   ROD 01-JUN-2024
DEFINITION  RNA guanine-N7 methyltransferase activating subunit [Mus musculus].
ACCESSION   NP_080273
VERSION     NP_080273.1
DBSOURCE    REFSEQ: accession NM_025997.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 119)
  AUTHORS   Gonatopoulos-Pournatzis,T., Dunn,S., Bounds,R. and Cowling,V.H.
  TITLE     RAM/Fam103a1 is required for mRNA cap methylation
  JOURNAL   Mol Cell 44 (4), 585-596 (2011)
   PUBMED   22099306
REFERENCE   2  (residues 1 to 119)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 119)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC130538.4 and
            AC102077.7.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011881.1, AK081301.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..119
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 45.71 cM"
     Protein         1..119
                     /product="RNA guanine-N7 methyltransferase activating
                     subunit"
                     /note="protein FAM103A1; RNMT-activating mini protein;
                     family with sequence similarity 103, member A1;
                     RNMT-activating mRNA cap methylating subunit; RNMT
                     actvating mRNA cap methylating subunit; RNMT-activating
                     mRNA cap methyltransferase subunit"
                     /calculated_mol_wt=14424
     Region          1..55
                     /region_name="Interaction with RNMT.
                     /evidence=ECO:0000250|UniProtKB:Q9BTL3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CQY2.1)"
     Region          10..87
                     /region_name="RAM"
                     /note="mRNA cap methylation, RNMT-activating mini protein;
                     pfam15320"
                     /db_xref="CDD:464643"
     Region          30..119
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CQY2.1)"
     Region          36..42
                     /region_name="RNMT-activating domain.
                     /evidence=ECO:0000250|UniProtKB:Q9BTL3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CQY2.1)"
     Site            36
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9BTL3; propagated from
                     UniProtKB/Swiss-Prot (Q9CQY2.1)"
     Region          56..119
                     /region_name="RNA-binding.
                     /evidence=ECO:0000250|UniProtKB:Q9BTL3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CQY2.1)"
     Site            85
                     /site_type="methylation"
                     /note="Omega-N-methylarginine.
                     /evidence=ECO:0000250|UniProtKB:Q9BTL3; propagated from
                     UniProtKB/Swiss-Prot (Q9CQY2.1)"
     Site            86
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9BTL3; propagated from
                     UniProtKB/Swiss-Prot (Q9CQY2.1)"
     CDS             1..119
                     /gene="Ramac"
                     /gene_synonym="2410047I02Rik; 2610204K14Rik; Fam103a1;
                     RAM; Rammet"
                     /coded_by="NM_025997.2:132..491"
                     /db_xref="CCDS:CCDS21406.1"
                     /db_xref="GeneID:67148"
                     /db_xref="MGI:MGI:1914398"
ORIGIN      
        1 msdtseeipn feemfasrft kddkeyqeyl krppesppiv eewnsraggn qrnrgnwlqd
       61 nrqfrgrdnr rgwpsdnrsn qwhgrswgnn nypqqrpepy yqqqytqygh nqrppygyy
//
