LOCUS       NM_001291138            8390 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Ral GTPase activating protein, beta subunit
            (non-catalytic) (Ralgapb), transcript variant 2, mRNA.
ACCESSION   NM_001291138 XM_006499364
VERSION     NM_001291138.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8390)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8390)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8390)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8390)
  AUTHORS   Skorobogatko,Y., Dragan,M., Cordon,C., Reilly,S.M., Hung,C.W.,
            Xia,W., Zhao,P., Wallace,M., Lackey,D.E., Chen,X.W., Osborn,O.,
            Bogner-Strauss,J.G., Theodorescu,D., Metallo,C.M., Olefsky,J.M. and
            Saltiel,A.R.
  TITLE     RalA controls glucose homeostasis by regulating glucose uptake in
            brown fat
  JOURNAL   Proc Natl Acad Sci U S A 115 (30), 7819-7824 (2018)
   PUBMED   29915037
REFERENCE   5  (bases 1 to 8390)
  AUTHORS   Chen,X.W., Leto,D., Xiong,T., Yu,G., Cheng,A., Decker,S. and
            Saltiel,A.R.
  TITLE     A Ral GAP complex links PI 3-kinase/Akt signaling to RalA
            activation in insulin action
  JOURNAL   Mol Biol Cell 22 (1), 141-152 (2011)
   PUBMED   21148297
  REMARK    GeneRIF: study reports the identification and characterization of a
            Ral GAP complex (RG1 (KIAA1219), RGC2) that mediates the activation
            of RalA downstream of the PI 3-kinase/Akt pathway
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ119771.1, AL844513.8, AL663091.13 and AI836674.1.
            
            On Mar 26, 2014 this sequence version replaced XM_006499364.1.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon in the 5' coding region, compared to variant 1, resulting in
            an isoform (b) that is shorter than isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC145260.1, SRR13861859.3212867.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-321               CJ119771.1         2-322
            322-467             AL844513.8         63408-63553
            468-670             AL844513.8         68689-68891
            671-834             AL844513.8         72941-73104
            835-1021            AL844513.8         75258-75444
            1022-1153           AL844513.8         77982-78113
            1154-1332           AL844513.8         79014-79192
            1333-1481           AL844513.8         79527-79675
            1482-1698           AL844513.8         79784-80000
            1699-1900           AL844513.8         83294-83495
            1901-2068           AL844513.8         85762-85929
            2069-2183           AL844513.8         86351-86465
            2184-2331           AL844513.8         87097-87244
            2332-2396           AL844513.8         88653-88717
            2397-2526           AL844513.8         90844-90973
            2527-2660           AL844513.8         92701-92834
            2661-2843           AL844513.8         96648-96830
            2844-2995           AL844513.8         98975-99126
            2996-3183           AL844513.8         104595-104782
            3184-3290           AL844513.8         106596-106702
            3291-3443           AL844513.8         108343-108495
            3444-3653           AL844513.8         109260-109469
            3654-3812           AL844513.8         115647-115805
            3813-3978           AL844513.8         118629-118794
            3979-4101           AL844513.8         120165-120287
            4102-4238           AL844513.8         124889-125025
            4239-4347           AL663091.13        5704-5812
            4348-4426           AL663091.13        6275-6353
            4427-4575           AL663091.13        7965-8113
            4576-8236           AL663091.13        8791-12451
            8237-8390           AI836674.1         1-154               c
FEATURES             Location/Qualifiers
     source          1..8390
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 78.72 cM"
     gene            1..8390
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /note="Ral GTPase activating protein, beta subunit
                     (non-catalytic)"
                     /db_xref="GeneID:228850"
                     /db_xref="MGI:MGI:2444531"
     exon            1..251
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            252..467
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     CDS             282..4769
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /note="isoform b is encoded by transcript variant 2; ral
                     GTPase-activating protein beta subunit; ral
                     GTPase-activating protein subunit beta"
                     /codon_start=1
                     /product="ral GTPase-activating protein subunit beta
                     isoform b"
                     /protein_id="NP_001278067.1"
                     /db_xref="CCDS:CCDS71179.1"
                     /db_xref="GeneID:228850"
                     /db_xref="MGI:MGI:2444531"
                     /translation="MYSEWRSLHLVIQSDQGHTSVLHSYPESVGREVANAVVRPLGQA
                     LGTSSVAGSESLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKD
                     SIPLPIIKEPNLYVQSILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSIMAR
                     ETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWK
                     TAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDN
                     ECIAQTWFRFLHMLSNPVDLSNPAVISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQI
                     FFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSAAVNTTPPHNRRHRAVTVN
                     KATMKTSTVTTAHTSKVQHQASSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSW
                     LFDAAFVHCKLHNGINRDNSMTAIATQASMEFRRKGSQMSTDTMVSNPVFDASEFPDN
                     YEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDYVCHPVLASVILN
                     SPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPL
                     PHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMI
                     LGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERP
                     AQALLRDYALNTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMV
                     DSGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDC
                     LKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFP
                     SPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFP
                     SVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPE
                     EVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEMHLEQQSEGELQKRS
                     FPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFF
                     DDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVD
                     VGKHPGWTGHVSTSWSINSCDDGEGSEPDEITSSEDVGASIFNGQKKVLYYADALTEI
                     AFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILKQPPLTLELVPNHTDSLNSSQRL
                     SPSSRMKKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSS
                     TSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVR
                     QTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCS
                     S"
     exon            468..670
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            671..834
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            835..1021
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1153
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1332
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1481
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1698
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            1699..1900
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            1901..2068
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2183
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            2184..2331
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            2332..2396
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            2397..2526
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            2527..2660
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            2661..2843
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            2844..2995
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            2996..3183
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            3184..3290
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            3291..3443
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            3444..3653
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            3654..3812
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            3813..3978
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            3979..4101
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            4102..4238
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            4239..4347
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            4348..4426
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            4427..4575
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     exon            4576..8378
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8192..8197
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /note="hexamer: AGTAAA"
     polyA_site      8214
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
     regulatory      8348..8353
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /note="hexamer: ATTAAA"
     polyA_site      8375
                     /gene="Ralgapb"
                     /gene_synonym="B230339M05Rik; p170"
                     /note="major polyA site"
ORIGIN      
        1 atttgacgcc accgcccctg gcagtcggaa gttgcttgaa cggagcccag ccggccggcc
       61 aagcgaccgg tgttcgtcgt cccctgggcg ccctgggaga gtcactgacg ggtggacgga
      121 ctgactgccg gtggagggcc ggccggggca gtggcagcgc gggccggatg gcgcgggtcg
      181 cgtgaggcgg caggccgagt gcggcccgcg gtgcgcccgc ccagcgatgc gggccccgcc
      241 cgtcgcctca ggtgccattt ggatagtact ttagtggcac aatgtactct gagtggcggt
      301 cactgcattt ggtgattcag agtgatcaag gccataccag tgtgctacac agctatccag
      361 agagtgttgg gcgagaggtg gcgaatgcag tggtccgtcc tcttgggcag gcattaggta
      421 cttcttcagt ggctggtagt gagagtttat taaaaactga caaagaagta aaatggacca
      481 tggaagtaat ttgctatgga ctgacccttc cattagatgg agagactgta aaatattgtg
      541 ttgatgtata tacagattgg attatggctt tggtgttgcc aaaagattct attccattac
      601 ccattattaa agaacctaat ctatatgttc aaagtatatt aaaacattta caaaatcttt
      661 ttgtaccaag acaggaacag ggctccagtc aaatccgact atgcttacaa gttctgagag
      721 ccattcagaa actggcccgg gagtcatcca tcatggctcg agaaacctgg gaagtcttac
      781 tgttgtttct tctgcaaatt aatgacatac ttctggcccc accaactgtt caaggtggca
      841 ttgctgagaa tctagcagag aagctgattg gtgttctctt tgaagtttgg ttactagctt
      901 gcacccggtg cttcccaaca cctccttatt ggaagacagc caaggagatg gtggctaact
      961 ggaggcacca ccctgcagtg gtggagcagt ggagcaaggt tatctgtgca ctgacctcca
     1021 gattgctccg ctttacatac ggtccttcat ttcctccatt taaagttcct gatgaagatg
     1081 ccaatctcat ccctccagaa atggacaatg agtgtattgc acaaacatgg tttcgatttt
     1141 tacacatgct aagtaacccc gtggatctga gtaacccagc tgttataagc tcaactccca
     1201 agtttcaaga acagttcctg aatgtgagcg ggatgccaca ggagctgagc cagtacccct
     1261 gccttaaaca tctgcctcag atattctttc gtgccatgcg tggaatcagc tgtctggtgg
     1321 atgcattctt aggcatttct cgacctcgat cagacagtgc tcccccaaca cccgtgaata
     1381 gattaagtat gccccagagt gctgctgtga ataccacacc accacataac cggaggcacc
     1441 gggctgttac tgtgaacaag gccacaatga agacgagtac agttactact gctcacacct
     1501 caaaagtcca gcaccaggca tcctccacct ctcctctgtc cagtccaaat cagactagtt
     1561 cagaacccag gccgctgcct gccccccgaa gaccaaaggt taacagcatc ttgaatctct
     1621 ttggatcgtg gttattcgat gcagcatttg ttcactgtaa actccataat ggaataaaca
     1681 gagacaacag catgactgcc attgcaaccc aagctagcat ggagtttcga cggaaagggt
     1741 cccaaatgtc aacagacacc atggtttcca accctgtgtt tgatgccagt gaatttcctg
     1801 ataactatga agcaggaaga gctgaggctt gtgggacatt atgtaggatt ttttgtagca
     1861 agaagactgg agaagagatt ctgccagctt atttatccag attttacatg cttttaattc
     1921 aaggtttgca gataaatgat tatgtatgcc atcctgtctt ggccagcgtt attctaaact
     1981 cccctccttt gttctgctgt gacttgaaag ggattgatgt tgtggttcct tactttattt
     2041 cagctcttga aaccattttg cctgacagag aactctcaaa attcaaaagc tatgtaaatc
     2101 caacagaatt gagaaggtca tccattaata tcctgctttc tttgttgccc ctccctcatc
     2161 attttggcac agtcagatct gaggtggtcc tagaaggaaa gtttagtaat gatgacagct
     2221 cttcttatga taaaccaata acttttctgt ccctgaagct gagacttgtg aatatactaa
     2281 taggtgcctt gcaaacagaa acggacccta acaacaccca aatgatacta ggggcaatgt
     2341 taaatattgt tcaagattct gcacttttag aagccattgg ttgccaaatg gaaatgggtg
     2401 gtggagaaaa caacctgaag agtcatagtc gcacaaacag tggcattagc tcagcaagtg
     2461 gaggaagcac agagcctaca acccctgata gcgagagacc tgctcaagct cttctgaggg
     2521 attatgctct taatacagat tcagctgctg ggctcctgat tcgcagcatt catctcgtca
     2581 ctcaacgact caactcccag tggcggcaag atatgagcat atccttggca gctctagagc
     2641 tcctctctgg cctggcaaag gtgaaggtga tggttgactc aggagaccgg aagcgtgcca
     2701 tcagttctgt gtgcagctac atcgtatacc aatgcagtcg gccagctcct cttcactccc
     2761 gggatctgca ctccatgata gtggcagcat ttcagtgtct ctgtgtctgg ctgacagagc
     2821 accctgatat gctggatgaa aaggattgcc ttaaggaagt actggagatt gtagaactgg
     2881 gtatctcagg aagcaaatcc aagaacagtg agcaagaagt caagtacaaa ggtgataagg
     2941 agccgaaccc tgcatccatg agggtaaagg acgccgccga agccactcta acatgtatca
     3001 tgcagttgct tggcgcattt ccttcaccca gtggtcctgc ttctccttgt agtctggtga
     3061 atgagaccac tctgatcaaa tactccaggc tgccaaccat aaacaagcat agtttccggt
     3121 actttgtttt ggataacagt gtcatcctgg caatgctgga gcaaccgctt ggaaatgagc
     3181 agaatgactt tttcccctct gtcactgtgc tggtccgggg aatgtctgga agacttgcgt
     3241 gggctcagca gctttgcctt ttacccagag gagcaaaagc aaatcagaag ctttttgtgc
     3301 ctgaacctcg cccagttcct aaaaatgatg ttggatttaa atattctgtg aaacatcggc
     3361 catttcctga agaggtggac aagattcctt ttgtaaaagc agacttgagc attccagatt
     3421 tacatgaaat tgtcactgaa gaattagaag agaggcatga aaaattaaga agtggtatgg
     3481 cacaacaaat tgcttatgag atgcacctgg aacagcagag cgagggggaa ctgcagaagc
     3541 gaagcttccc tgaccctgtt acggactgta agcctccacc tcctgcccag gaatttcaga
     3601 cagcccgcct tttcctttct cactttggat ttttatcctt agaggcatta aaggaacctg
     3661 caaatagtcg tctacctcct catcttattg cactcgattc taccatacct ggattttttg
     3721 atgacattgg gtatctggat ctcctgccat gccggccttt tgacactgtt tttattttct
     3781 acatgaagcc aggtcagaaa acaaaccaag agattttaaa gaatgtggag tcttccagaa
     3841 atgttcagcc acatttccta gaatttttgc tctccctggg ctggtcagta gatgtgggga
     3901 aacaccccgg ttggacagga catgtgtcca ccagttggtc aatcaatagt tgtgatgatg
     3961 gtgaagggtc tgaaccagat gaaataactt cctctgaaga cgttggggct agcattttca
     4021 acgggcagaa gaaggtgctg tattatgctg atgccctaac agaaatagct tttgtggttc
     4081 cttctcctgt ggagtcactg actgattcat tggaaagtaa catctcagac caagatagtg
     4141 actcaaatat ggatcttatg ccgggaattc tgaagcagcc acccctgaca cttgagttgg
     4201 tccccaatca cacagacagt cttaattcct cacagaggct cagtcccagt tccagaatga
     4261 agaagctgcc tcagggtcgc cctgtgcccc cgcttggacc tgagacaaga gtatctgtag
     4321 tctgggtgga acgctacgat gatatagaaa actttccact ctcagatctg atgacagaga
     4381 tcagcactgg tgtagagact actgcaaata gtagcacttc tctgagatct acaactcttg
     4441 aaaaagaagt cccagtaatc ttcattcacc ctttaaacac tggattgttc cggataaaaa
     4501 tccaaggagc cactggaaaa tttaacatgg tcatacctct ggttgatggg atgatagtca
     4561 gccgtcgagc acttggcttt ctggtgaggc agacggtaat aaacatttgt agaagaaaga
     4621 gactggagag tgattcctac agtccaccac atgtccgtcg gaaacagaaa atcactgaca
     4681 ttgtcaacaa atatcggaat aagcagttgg agccagagtt ttatactgcc cttttccagg
     4741 aggttggact caagaactgc agttcttaga atgcattttg tccaggtcag tgaactccag
     4801 agtgggctct aacatcaaag caagacagtc ctgtaaaaat caaagctaat cactcctaag
     4861 agctcactgc tgaatcagaa gaagaaatac gatgtgaagc cactggcttg aagacccagc
     4921 tttccagtga agggaccctg cacagtcaca ctcctgctga aaacaacaac aagcatttta
     4981 gccataaact ttcttttaaa agtgacaatt ttagtaaaat atcagccttt tgaggaaaag
     5041 gctttatgca tcagttaaat acatgcattg atagtgtcaa caagtttgca agttagaaac
     5101 tgaagatagt tttatacctc gctttttagg agggtgtatt caaaattaaa atctgtctca
     5161 gaatcttcca gaacttttta ggctcaagtt gacactgtgg agaaggaaag gctgcagcgt
     5221 tgtcctcgtg tggattcact tgtcacccca tcacactgac agagggtgaa acaaatgagt
     5281 tttgttcaga taagaagtcc aacattaaaa tatttcctat ttttctctcc atatttaaca
     5341 agttgtccct ctgatcgctg tggagctctg tcaaatggct cagcttctta gcagacgtgg
     5401 gcagtggagg ccctgctgta tctctgaata gtatactgcc atgtttatgg ttaaaggctg
     5461 tgagagaacg atggcacctc ccttctccgt tgctgttcag tttaatggaa gggtgacagg
     5521 ttagacgtga ctcctccatt aaacaccaag aaatgtgagt tcatagcagg ggcttcatcc
     5581 atattgattg caggaccaag ttgcaagctg cagtagttga ggaaaggttc taatttgtgg
     5641 ctcaggaagt agtgtcccac tcacttagct ccttagaggg cacccagccc acaatccaca
     5701 gaactcagtg ccacctcctt aggtggctgc tgctgtttgg tttctagcct tagccagctg
     5761 aaggcagaag tctctgccat ctcactgctg cttttctgcc agggacaaag ctttggaagt
     5821 ggccagaacc aaattgtttt agaaggactc ctgttacagc actcagtata tacctgtttt
     5881 tatgttctcc ttcaataaga tctttttgtc ttagaaaaca agtgacattt atagtccaaa
     5941 gagaaataat cacacttgaa tggtggtgtt cccactggcc ctctgttgtc attaaagtgt
     6001 agaccaggac tccagtgatt ggtttgaggt ttcttttctt tggatgtcag gggcaatgtt
     6061 gggccagctc tcctgtgcag atgcctccat tctagacatg tgctctgcca tctggaagca
     6121 caaagcatgg ctgtagcagt ctttggtctg aagtttgcca ccaccccttt tatttttttt
     6181 ccctcagctc aggtacagac agccatcccc actcccaccc ccatcttcct tgtcctcttc
     6241 ttcccctatg agtttccatt cgaggcaaag agctttctgt ctttgattcc ctctgaagtc
     6301 aggcaataat ctaatgttcc caggtgattc cctgagatgg ggaatggtga aaattagtga
     6361 atttttccct aaaaatattc ttgtaactca gcaagaatag gtgaaattga acaacagcta
     6421 agatacttcc agatttgacc cttcatgggc aaagtgggtt cttgttctat ccaaggtgaa
     6481 caaagaattt atacacatac atgcaacttc taacattcca gagggtacaa atatctgata
     6541 aaggtggact ttctttgtgt gattcttctc aaaaccttgt ttggatgttt tttaaatgat
     6601 actggaaaaa taacgtatgg gttatatgtg taggagtggg cttactggcc ttcccccttc
     6661 atttggctct aatttctggt aactctttat aattctgatt attttggtaa gcgaaccacc
     6721 atggcagatg cagtttgaaa tctggggcat gcagtggttc cccaagggaa gagggctgcc
     6781 ccctgccccc tgaaggagag aagcatcggt gtgcacagcc agcagagctt gggatgcacc
     6841 gccactgctt gcttctgctc cacacaccat ctccccagca aaaggctggc aagaagagct
     6901 tgggccttcg cagaggcgtt tggaatcctg ctcactgagc tcaccctcct gcctgcactg
     6961 aggtcacttt gaacagaatc atggcagagg aacatcctta gagcctaaca gtaatctcag
     7021 tagttcactt gataaatttg ccaccacagg ttcagaaact ttggggggaa actgggacca
     7081 gtctggactg tggcttaagc tattcagttg ctgtagctga atacccaggc accttcaaac
     7141 aggaaaacat ttcccaaggg tatttaggct ggtggcccat tctgttcact tttgaagctg
     7201 ggggtgaggg tgggggtggg gcttctactt tggccggaac atggaaaacg gggctcttaa
     7261 caccaccttc cccttttgtc tagggtttct tccttaggcc ttcctggcct ttggcccctt
     7321 gaaaagaata attacatggt agggcagccc tctccagcca tactgatgca tgtgccatgt
     7381 gtacacaagc atctccccct tccagcacct cgattttagg gtagctccat ctctggactc
     7441 acatacaaaa atacgcacag tttggcgggc cctctcagtg tctaacccat gggtagtagg
     7501 gcaatctgga aggcccgctt ccacatttat gagctaggga agaaccaggt ttggctggct
     7561 gccattacag acagtgatga ggtttccagg gtgtttattc ctattaaaaa gtggaacttc
     7621 cctcacatac tcagccttgg gtacagctgg ataaagctgg tagggactgc cttggatatt
     7681 atgtggcact ttcctggaag cagtcgtcct ttagcattta aagcctgttc aggccagatc
     7741 ttctgtgccg ccagcgacca tcagcttcca cccacccatc tgttctagca cttcctgaca
     7801 gcccctcttc ctgaggggtc cacttggaca gggagccact gatcacactg ctggccgggc
     7861 catgcactgc atagggtttg ctcccagtag ccacccttgt tcttcacaca ggctttttta
     7921 atggtgaggg agaaggtata atttgggatt ccacagtgcc ttgcatacag taggcgccca
     7981 atacccattt gttgaagcaa atcaagttcc ttgttcccac agtaaccaag gcatcttcct
     8041 cctctgaagg gcttggcggt tgtggctaaa aactaagcat cattatttgc tcgaaaccat
     8101 atttacaatt tgtatgaatt tcggtatatt gccaagatgg gatctttttc ctattgtatt
     8161 ttctgtaaat atttctgcca ctgacttgta aagtaaagga gatgtaaata tgaaggtgtg
     8221 cctgtgtccc ttgctgcctc cgttggatct gggtcagcct gggaagaagg tgcagagctg
     8281 ttcgtattta tgcctgtcct ttgtccacaa gaaacccacg ggatattgaa tgtactacac
     8341 acagtcaatt aaattttaag gagcttctta tctaataaaa aaaaaaaaaa
//
