LOCUS       NM_001103367            2198 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus retinoic acid induced 2 (Rai2), transcript variant 2,
            mRNA.
ACCESSION   NM_001103367
VERSION     NM_001103367.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2198)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2198)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   3  (bases 1 to 2198)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   4  (bases 1 to 2198)
  AUTHORS   Walpole,S.M., Hiriyana,K.T., Nicolaou,A., Bingham,E.L., Durham,J.,
            Vaudin,M., Ross,M.T., Yates,J.R., Sieving,P.A. and Trump,D.
  TITLE     Identification and characterization of the human homologue (RAI2)
            of a mouse retinoic acid-induced gene in Xp22
  JOURNAL   Genomics 55 (3), 275-283 (1999)
   PUBMED   10049581
REFERENCE   5  (bases 1 to 2198)
  AUTHORS   Jonk,L.J., de Jonge,M.E., Vervaart,J.M., Wissink,S. and Kruijer,W.
  TITLE     Isolation and developmental expression of retinoic-acid-induced
            genes
  JOURNAL   Dev Biol 161 (2), 604-614 (1994)
   PUBMED   8314004
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY283618.1, BB857753.1, AK143442.1, BY589134.1 and BB173369.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143442.1, SRR1660811.194111.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                BY283618.1         9-37
            30-33               BB857753.1         31-34
            34-1911             AK143442.1         2-1879
            1912-2197           BY589134.1         161-446
            2198-2198           BB173369.1         301-301
FEATURES             Location/Qualifiers
     source          1..2198
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 74.07 cM"
     gene            1..2198
                     /gene="Rai2"
                     /gene_synonym="3f8"
                     /note="retinoic acid induced 2"
                     /db_xref="GeneID:24004"
                     /db_xref="MGI:MGI:1344378"
     exon            1..232
                     /gene="Rai2"
                     /gene_synonym="3f8"
                     /inference="alignment:Splign:2.1.0"
     exon            233..2198
                     /gene="Rai2"
                     /gene_synonym="3f8"
                     /inference="alignment:Splign:2.1.0"
     CDS             257..1846
                     /gene="Rai2"
                     /gene_synonym="3f8"
                     /codon_start=1
                     /product="retinoic acid-induced protein 2"
                     /protein_id="NP_001096837.1"
                     /db_xref="CCDS:CCDS30507.1"
                     /db_xref="GeneID:24004"
                     /db_xref="MGI:MGI:1344378"
                     /translation="MDDLQSQNLSMDMTDSPPTLANNRLENRMAQLITTEAWNINSTD
                     LVKKALVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAP
                     ELNPNGNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQGAE
                     DSEAQPQLLDLRIPSQPQEPALPFEAVLQNLFPTQGSLGPPPCQPPPGYAPVPPQPFN
                     SPLSPLVPPATLLVPYPVIVPLPVPVPIPIPVPVPQSTESKFSPTFPKPPSSFGLHSF
                     KGTQTTLEKDELKPLDILQSKEYFQLSRHTVIKMGSENEALDLSMKSVPWLKAGEASP
                     PVFQEDAALDLSLAAHRKAEAPPETLYNNSGSADIQGHTILEKLSSGMEMPFAPAKCS
                     EASAMMESHSSNSNGTEMVSQPSHPGSELKAENNIEILSESQAAKVIVSVEDAVPAIF
                     CGKIKGLSGVSTKNFSFKREDSVLQGYDINSQGEESLGNAEPLRKPIKNRSIKLKKVN
                     SQEIHMLPIKKQRLATFFPRK"
     regulatory      2179..2184
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rai2"
                     /gene_synonym="3f8"
     polyA_site      2198
                     /gene="Rai2"
                     /gene_synonym="3f8"
ORIGIN      
        1 atagtaaagg ccaggcgctg cacgcagaca cacactctcc cggacacagg caaacacgca
       61 cacacacaca accggcagtg gcggtagcga cagcggcttg gtgacagcag cgacaggggc
      121 tcccatccgc tgtgcacccc cttcaggcgc ccagcggcga ggccagaccc agagagttcc
      181 cacactagcg tccaccccgt ggcttcctgg aggcggcggc ccggatcccg aggccacgtg
      241 gcaccggagc caagtgatgg atgacctgca gtcccagaat ctttccatgg acatgactga
      301 ctcccctccc actttggcta ataacagact ggagaaccgc atggcccagc tgataactac
      361 cgaggcctgg aacatcaact ccactgacct ggtaaagaag gccctggtga ccgttccggc
      421 cccatcaatt ctgaaccccc cagctgagtc ccagagtggc atggctctga aggtagcagc
      481 caccgtgctg cagcccctgt gccttgggga aagcccagtg gtgatgccca ttcacatgca
      541 ggtggaggga agctctgcgc cagagctcaa ccccaatggc aacgctacct acgttatgac
      601 gacacaaggc cccgtgcagc taccagtggt gttggaacag catgttttcc agcacctcaa
      661 ctcccctcta gtcctgccac aggaggcccc gtgctcctcc aatgctatcc acaacaacct
      721 cttccagggg gctgaggact ctgaggccca gcctcagctc ctggacctga ggatcccaag
      781 tcagccacag gagcccgcat tgccttttga agctgtgctc cagaatttat tccccaccca
      841 aggctctctg ggccctccac cctgccagcc tcctcctggc tatgctccag tgcctcccca
      901 gccctttaac tcccccttgt cccccctagt cccgccagct accctcttgg tgccctatcc
      961 tgtgattgtc cccttgccag ttccagtgcc catccccatc cctgtcccag tgcctcagag
     1021 tactgaatcc aagttcagcc ccactttccc caagccgcca tcttccttcg gcttgcactc
     1081 ctttaaaggc acccagacca ctctggaaaa ggacgaactg aagcccttag acatcctcca
     1141 gtcaaaggag tatttccagc tcagccgcca cacagtcatc aagatgggga gtgagaatga
     1201 ggccctggat ctgtccatga agtcagtgcc ctggctcaag gctggggaag ctagcccccc
     1261 agtctttcaa gaggatgcag ccctagatct gtctttggca gcccaccgaa aagctgaggc
     1321 tcctccagag acattgtata acaacagtgg gtcagcagac atccagggtc acaccatact
     1381 ggagaaactt tccagtggca tggaaatgcc ctttgcccct gccaagtgtt ctgaagcctc
     1441 agccatgatg gagagccaca gcagcaacag caacggcact gagatggtca gtcagcccag
     1501 ccatcctggc agtgagctga aggctgaaaa taacattgag atcttaagtg agtctcaggc
     1561 ggccaaggtc attgtgtcag ttgaagacgc cgtgcctgcc atcttctgtg gcaagattaa
     1621 aggcctctca ggggtatcca ccaaaaactt ctccttcaaa agagaagact ctgtgcttca
     1681 gggttatgat atcaacagcc aaggagaaga gtccctggga aacgccgagc cccttaggaa
     1741 acccatcaaa aaccggagca taaagttaaa gaaagtgaac tcccaggaaa tacacatgct
     1801 tccaattaaa aaacaacggc tggccacctt tttcccaaga aagtaaataa gagctttaaa
     1861 acgtttttat gattaagacg tggggaaagg tgcattgttt tttttttttt tttaaaggca
     1921 ctaagacaaa ttatctttgt taattatttt ggggtatagg tgggagcaga aaggcaaatt
     1981 agctagtatc attttctttt ttaatttttg acttttcaca aatgagtaaa taagagcaac
     2041 ctatttttca agcagattgc acattttttt gcagctttaa tggaatattg ggtgaatcag
     2101 aggggtaaga gctattttca ttgccacaaa gtgctttgat gatgtaatac ctaataaagg
     2161 gtaggatgaa tatttcacaa taaatgtttg tttgcact
//
