LOCUS       NM_009021               7348 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus retinoic acid induced 1 (Rai1), transcript variant 1,
            mRNA.
ACCESSION   NM_009021
VERSION     NM_009021.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7348)
  AUTHORS   Chang,Y.T., Lee,Y.J., Haque,M., Chang,H.C., Javed,S., Lin,Y.C.,
            Cho,Y., Abramovitz,J., Chin,G., Khamis,A., Raja,R., Murai,K.K. and
            Huang,W.H.
  TITLE     Comparative analyses of the Smith-Magenis syndrome protein RAI1 in
            mice and common marmoset monkeys
  JOURNAL   J Comp Neurol 532 (1), e25589 (2024)
   PUBMED   38289192
  REMARK    GeneRIF: Comparative analyses of the Smith-Magenis syndrome protein
            RAI1 in mice and common marmoset monkeys.
REFERENCE   2  (bases 1 to 7348)
  AUTHORS   Javed,S., Chang,Y.T., Cho,Y., Lee,Y.J., Chang,H.C., Haque,M.,
            Lin,Y.C. and Huang,W.H.
  TITLE     Smith-Magenis syndrome protein RAI1 regulates body weight
            homeostasis through hypothalamic BDNF-producing neurons and
            neurotrophin downstream signalling
  JOURNAL   Elife 12, 90333 (2023)
   PUBMED   37956053
  REMARK    GeneRIF: Smith-Magenis syndrome protein RAI1 regulates body weight
            homeostasis through hypothalamic BDNF-producing neurons and
            neurotrophin downstream signalling.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7348)
  AUTHORS   Chang,H.C., Lee,Y.J., Javed,S., Haque,M., Chang,Y.T., Lin,Y.C.,
            Oram,C. and Huang,W.H.
  TITLE     rAAV-CRISPRa therapy corrects Rai1 haploinsufficiency and rescues
            selective disease features in Smith-Magenis syndrome mice
  JOURNAL   J Biol Chem 299 (1), 102728 (2023)
   PUBMED   36410433
REFERENCE   4  (bases 1 to 7348)
  AUTHORS   Chang,Y.T., Kowalczyk,M., Fogerson,P.M., Lee,Y.J., Haque,M.,
            Adams,E.L., Wang,D.C., DeNardo,L.A., Tessier-Lavigne,M.,
            Huguenard,J.R., Luo,L. and Huang,W.H.
  TITLE     Loss of Rai1 enhances hippocampal excitability and epileptogenesis
            in mouse models of Smith-Magenis syndrome
  JOURNAL   Proc Natl Acad Sci U S A 119 (43), e2210122119 (2022)
   PUBMED   36256819
  REMARK    GeneRIF: Loss of Rai1 enhances hippocampal excitability and
            epileptogenesis in mouse models of Smith-Magenis syndrome.
            Erratum:[Proc Natl Acad Sci U S A. 2022 Dec 27;119(52):e2219265119.
            doi: 10.1073/pnas.2219265119.. PMID: 36534813]
REFERENCE   5  (bases 1 to 7348)
  AUTHORS   Zhou,J., Hamdan,H., Yalamanchili,H.K., Pang,K., Pohodich,A.E.,
            Lopez,J., Shao,Y., Oses-Prieto,J.A., Li,L., Kim,W., Durham,M.A.,
            Bajikar,S.S., Palmer,D.J., Ng,P., Thompson,M.L., Bebin,E.M.,
            Muller,A.J., Kuechler,A., Kampmeier,A., Haack,T.B.,
            Burlingame,A.L., Liu,Z., Rasband,M.N. and Zoghbi,H.Y.
  TITLE     Disruption of MeCP2-TCF20 complex underlies distinct
            neurodevelopmental disorders
  JOURNAL   Proc Natl Acad Sci U S A 119 (4) (2022)
   PUBMED   35074918
REFERENCE   6  (bases 1 to 7348)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   7  (bases 1 to 7348)
  AUTHORS   Toulouse,A., Rochefort,D., Roussel,J., Joober,R. and Rouleau,G.A.
  TITLE     Molecular cloning and characterization of human RAI1, a gene
            associated with schizophrenia
  JOURNAL   Genomics 82 (2), 162-171 (2003)
   PUBMED   12837267
REFERENCE   8  (bases 1 to 7348)
  AUTHORS   Slager,R.E., Newton,T.L., Vlangos,C.N., Finucane,B. and Elsea,S.H.
  TITLE     Mutations in RAI1 associated with Smith-Magenis syndrome
  JOURNAL   Nat Genet 33 (4), 466-468 (2003)
   PUBMED   12652298
REFERENCE   9  (bases 1 to 7348)
  AUTHORS   Seranski,P., Hoff,C., Radelof,U., Hennig,S., Reinhardt,R.,
            Schwartz,C.E., Heiss,N.S. and Poustka,A.
  TITLE     RAI1 is a novel polyglutamine encoding gene that is deleted in
            Smith-Magenis syndrome patients
  JOURNAL   Gene 270 (1-2), 69-76 (2001)
   PUBMED   11404004
REFERENCE   10 (bases 1 to 7348)
  AUTHORS   Imai,Y., Suzuki,Y., Matsui,T., Tohyama,M., Wanaka,A. and Takagi,T.
  TITLE     Cloning of a retinoic acid-induced gene, GT1, in the embryonal
            carcinoma cell line P19: neuron-specific expression in the mouse
            brain
  JOURNAL   Brain Res Mol Brain Res 31 (1-2), 1-9 (1995)
   PUBMED   7476016
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC049785.1, AK154252.1 and AL669954.6.
            
            On Dec 15, 2005 this sequence version replaced NM_009021.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154252.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-161               BC049785.1         1-161
            162-689             AK154252.1         1-528
            690-5453            AL669954.6         24061-28824
            5454-7293           AK154252.1         5294-7133
            7294-7348           AL669954.6         37929-37983
FEATURES             Location/Qualifiers
     source          1..7348
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="NOD"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 37.81 cM"
     gene            1..7348
                     /gene="Rai1"
                     /gene_synonym="Gt1"
                     /note="retinoic acid induced 1"
                     /db_xref="GeneID:19377"
                     /db_xref="MGI:MGI:103291"
     exon            1..382
                     /gene="Rai1"
                     /gene_synonym="Gt1"
                     /inference="alignment:Splign:2.1.0"
     exon            383..512
                     /gene="Rai1"
                     /gene_synonym="Gt1"
                     /inference="alignment:Splign:2.1.0"
     exon            513..6039
                     /gene="Rai1"
                     /gene_synonym="Gt1"
                     /inference="alignment:Splign:2.1.0"
     CDS             529..6198
                     /gene="Rai1"
                     /gene_synonym="Gt1"
                     /codon_start=1
                     /product="retinoic acid-induced protein 1"
                     /protein_id="NP_033047.2"
                     /db_xref="CCDS:CCDS24784.1"
                     /db_xref="GeneID:19377"
                     /db_xref="MGI:MGI:103291"
                     /translation="MQSFRERCGFHGKQQNYPQTSQETSRLENYRQPGQAGLSCDRQR
                     LLAKDYYSPQPYTGYEGGTGTPSGTVATAAADKYHRGSKSLQGRPAFPSYVQDSSPYP
                     GRYSGEEGLQTWGGPQPPPPQPQPLPGAVSKYEENLMKKTVVPPPNRQYPEQGPQLPF
                     RTHSLHVPPPQPQQPLAYPKLQRQKPQNDLASPLPFPQGSHFPQHSQSFPTSSTYAPT
                     VQGGGQGAHSYKSCTAPSAQPHDRPMSANANLAPGQRVQNLHAYQPGRLGYEQQQQAL
                     QGRHHTQETLHYQNLAKYQHYGQQGQGYCPPDTAVRTPEQYYQTFSPSSSHSPARSVG
                     RSPSYSSTPSPLMPNLENFPYSQQPLSTGAFPTGITDHSHFMPLLNPSPTDAASSVDP
                     QAGNCKPLQKEKLPDNLLSDLSLQSLTALTSQVENISNTVQQLLLSKATMPQKKGVKN
                     LVSRTPEQHKSQHCSPEGSGYSAEPAGTPLSEPPSSTPQSTHAEPQDTDYLSGSEDPL
                     ERSFLYCSQARGSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSLHSTLPLDS
                     FSKFVAGERDCPRLLLSALAQEDLASEILGLQEAIVEKADKAWAEASSLPKDNGKPPF
                     SLENHGACLDTVAKTSWSQPGEPETLPEPLQLDKGGSTKDFSPGLFEDPSVAFATTDP
                     KKTSSPLSFGTKPLLGTATPDPTTAAFDCFPDTPTASSVDGANPFAWPEENLGDACPR
                     WGLHPGELTKGLEQGAKASDGVGKADAHEASACMGFQEDHAIGKPAAALSGDFKQQEA
                     EGVKEEVGGLLQCPEVAKANQWLEESRHCCSSTDFGDLPLLPPPGRKEDLEAEEEYSS
                     LCELLGSPEQRPSLQDPLSPKAPLMCTKEEAEEALDTKAGWVSPCHLSGEPAVLLGPS
                     VGAQSKVQSWFESSLSHMKPGEEGPEMERAPGSSGTSQGSLAPKPNKPAVPEGPIAKK
                     EPVPRGKSLRSRRVHRGLPEAEDSPCRVPALPKDLLLPESCTGPPQGQAEGAGAPGRG
                     LSEGLPRMCTRSLTALSEPQTPGPPGLTTTPTPPDKLGGKQRAAFKSGKRVGKPSPKA
                     ASSPSNPAALPVASDSSPMGSKTKEPDSPSMPGKDQRSMVLRSRTKPQQVFHAKRRRP
                     SESRIPDCRATKKLPANNHLPTAYKVSSGPQKEGRMNQRVKVPKPGTGNKLSDRPLHT
                     LKRKSAFMAPVPAKKRSLILRSNNGSGGDGREERAESSPGLLRRMASPQRARPRGSGE
                     PPPPPPLEPPAACMGLSTQSSLPSAVRTKVLPPRKGRGLKLEAIVQKITSPGLKKLAC
                     RVAGAPPGTPRSPALPERRPGGSPAGAEEGLGGMGQMLPAASGADPLCRNPASRSLKG
                     KLLNSKKLSSAADCPKAEAFMSPETLPSLGTARAPKKRSRKGRTGTLGPSKGPLEKRP
                     CPGQPLLLAPHDRASSTQGGGEDNSSGGGKKPKTEELGPASQPPEGRPCQPQTRAQKQ
                     PGQASYSSYSKRKRLSRGRGKTAHASPCKGRATRRRQQQVLPLDPAEPEIRLKYISSC
                     KRLRADSRTPAFSPFVRVEKRDAYTTICTVVNSPGDEPKPHWKPSSSAASSSTSSSSL
                     EPAGASLTTFPGGSVLQQRPSLPLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLG
                     DLCGPYYPEHCLPKKKPKLKEKARLEGTLEEASLPLERTLKGLECSASTTAAAPTTAT
                     ITTPTALGRLSRPDGPADPAKQGPLRTSARGLSRRLQSCYCCDGQGDGGEEVAQADKS
                     RKHECSKEAPTEPGGDTQEHWVHEACAVWTSGVYLVAGKLFGLQEAMKVAVDMPCTSC
                     HEPGATISCSYKGCIHTYHYPCANDTGCTFIEENFTLKCPKHKRLPL"
     exon            6040..6133
                     /gene="Rai1"
                     /gene_synonym="Gt1"
                     /inference="alignment:Splign:2.1.0"
     exon            6134..6183
                     /gene="Rai1"
                     /gene_synonym="Gt1"
                     /inference="alignment:Splign:2.1.0"
     exon            6184..7348
                     /gene="Rai1"
                     /gene_synonym="Gt1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7324..7329
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rai1"
                     /gene_synonym="Gt1"
ORIGIN      
        1 ccgcacgtcg cccgcccgcc cgccgctctt cctgtgtgga ggggatcgca tttctctcgg
       61 gctcccgcgg gcatcaggca ggcccggcag ggtgcgcggt cagggcccgc tacgcgcgcc
      121 gccggctccc ggcgccccgg tgccaccccc gctcgcgcct gggctcggac aggccgcttg
      181 cagagccagg cggtggtggc ggtggtggcg gcggtggcca gggtagctgg ctgccttgtc
      241 gaggtccgag gaaggggccc cgcggcccac cctctttccc gcccgggcgg ccgtcgtgcc
      301 ggacacccat gggcgcgcgg gcctccgggc cgcgaagtcg cagcgccgga cgccgggccc
      361 cggagtgacc gcgggctccg aggatctcat ctggcggtcg ggtactggaa gaagcgaggg
      421 ggagagcgca ccgttgcaga gagacggcaa gagaaaaggg agactgagag tcgcgccacg
      481 ccggcgcccc aagacccagg aggagcccgc agataaccag cccgagtcat gcagtctttt
      541 cgagaaaggt gtggtttcca tggcaaacag caaaactacc cacagacctc ccaggagaca
      601 tcgcgcctgg agaactacag gcagccgggt caggctgggc taagctgtga tcggcagcgg
      661 ctgctggcca aggactacta cagccctcag ccctatacag gctatgaggg tggcactggt
      721 acaccttctg gcacggtggc cacagcagct gcagacaagt accaccgagg cagcaaatcc
      781 ctgcagggga ggccagcttt ccccagctat gttcaagaca gcagccccta cccagggcgc
      841 tactctggcg aggaaggtct tcagacctgg gggggcccac agccaccgcc tcctcagcca
      901 cagcctctgc ccggggcagt gagcaagtat gaggagaacc tgatgaagaa gacagttgtg
      961 cctcctccaa acaggcagta ccctgagcag ggcccccagc ttcccttccg gactcacagc
     1021 ctgcatgtcc caccaccaca gcctcagcag cccctggctt accccaaact ccaaaggcag
     1081 aaaccacaga acgaccttgc ctcccctctg cccttccccc agggcagcca ctttccccag
     1141 cattcccagt ccttccctac ctcctccact tatgccccaa cagtgcaggg tggtgggcag
     1201 ggggcccact cctacaagag ctgcacagca ccatctgccc agcctcatga taggccgatg
     1261 agtgccaatg cgaacctggc tccagggcaa cgggtccaga atcttcacgc ttaccagcct
     1321 ggccgccttg gctacgagca gcagcagcaa gcacttcaag gccgtcacca cacccaggaa
     1381 acactccact accagaacct cgccaagtac caacactatg gacagcaagg ccagggctac
     1441 tgtccaccgg acacagctgt caggactcca gagcagtatt accagacttt cagcccgagc
     1501 tccagccact cccctgcacg gtctgtgggt cgctcccctt cctatagctc caccccgtca
     1561 ccactgatgc ccaatctgga gaacttcccc tatagccagc agccgcttag tactggggcc
     1621 ttccccacag gcatcacaga ccacagccac tttatgcccc tgcttaaccc gtccccaaca
     1681 gatgctgcca gctctgtgga cccccaggcc ggcaactgca agcccctgca aaaggagaag
     1741 ctgcctgaca acttgctctc cgacctcagc ctgcagagcc tcacagcgct cacctcccag
     1801 gtggaaaaca tctccaacac cgtgcagcag ctcttgctgt ccaaagctac catgccacag
     1861 aagaaagggg tcaagaacct cgtgtccagg actccagagc agcacaaaag ccagcactgt
     1921 agccctgaag gcagcggcta ctcagctgag ccagcgggca caccgctgtc tgagccgccg
     1981 agcagcacgc cacagtccac ccatgctgag ccacaggaca ctgactacct gagtggctct
     2041 gaggacccgc tagagcgcag cttcctctac tgcagccagg cccggggcag ccccgccagg
     2101 gtcaacagca actccaaggc taagcccgag tctgtgtcca cctgttctgt gacctcacct
     2161 gatgacatgt ccaccaagtc cgacgactct ttccagagcc tgcacagtac tctgcccctg
     2221 gacagcttct ccaaatttgt ggcaggcgag cgggactgcc cgcggctgct gctcagtgcc
     2281 ctggcacagg aagatctggc ctccgagatc ctgggactgc aggaagccat tgttgagaag
     2341 gctgacaagg cctgggctga ggcttccagc ctgcccaagg acaatggcaa gccacccttc
     2401 tcactggaga accatggcgc ctgcctggac actgtagcaa agacttcatg gtcacagcca
     2461 ggggagccag agaccctccc tgagcctttg cagctggaca agggtggcag caccaaggac
     2521 ttcagcccgg ggctgtttga agacccctct gtggcctttg ccaccactga cccgaagaaa
     2581 acaagcagtc ccctgtcctt cggcaccaag cctttgctag ggactgccac tcctgacccc
     2641 accacagcag catttgactg ctttccagat acacccactg ccagctcggt ggatggtgcc
     2701 aacccctttg cctggccaga ggagaacctg ggcgatgctt gtcctcgttg gggcctccac
     2761 cctggtgagc ttaccaaggg cttggaacag ggtgcaaaag cctcggacgg cgtgggcaag
     2821 gcagatgcac acgaggcctc tgcttgcatg ggcttccagg aggatcatgc catcgggaag
     2881 ccagcagccg cactgtccgg ggacttcaaa cagcaggagg cagagggggt gaaagaggag
     2941 gtgggtgggt tgctgcagtg ccccgaggtg gccaaggcca accagtggct ggaggagagc
     3001 cgccattgct gttcctccac tgacttcggg gacctgccac tgttgccgcc ccctggcagg
     3061 aaggaggacc tggaagctga agaggagtac tcttctctgt gtgaactgct ggggagccct
     3121 gagcagaggc ccagcctgca ggacccgttg tccccaaagg ccccgctgat gtgcaccaag
     3181 gaggaggcag aggaggcgct ggacaccaag gctggctggg tctctccatg tcacctctct
     3241 ggggagcctg ctgtcctact gggcccctct gtgggtgccc aatcaaaggt tcagagctgg
     3301 tttgaatctt ctctgtcaca catgaagccg ggagaagaag ggccagagat ggagagggct
     3361 ccaggtagtt ccggcacctc acaaggctcc ttggccccga agcctaacaa gcctgctgta
     3421 cctgaggggc ccattgctaa gaaagagcct gtgccacggg gtaagagctt acggagccgg
     3481 cgagtacacc gggggctgcc tgaggcggaa gactctccgt gcagggtgcc agcacttccc
     3541 aaagacctct tgctcccaga gtcttgcaca gggcctccac agggacaggc cgagggggct
     3601 ggagccccag gccgggggct gtcagaaggg ctccccagaa tgtgtacccg ctcgcttaca
     3661 gctctgagtg agccccagac tcctggacct ccgggcctga ctaccacccc cacgcctccc
     3721 gacaaactgg gaggtaagca gcgagctgcc ttcaagtctg gcaagcgggt cggaaaacca
     3781 tcacccaagg ctgcatccag ccccagcaac cctgctgccc tgcctgttgc ctcagacagc
     3841 agccccatgg gctccaagac caaggagcca gactctccca gcatgcctgg caaggaccag
     3901 cgctccatgg tcctccggtc tcgcaccaaa ccccagcagg tcttccatgc caaacggcgg
     3961 cggccctcgg agagccggat cccagactgc cgtgccacca agaagctccc tgctaacaac
     4021 catttaccca ctgcgtacaa ggtctccagt gggccccaga aggaaggtcg gatgaaccag
     4081 cgggtcaaag tacccaagcc tggtacagga aacaagcttt cagatcggcc tctccacacg
     4141 ctcaagagga agtcggcttt catggcacct gtccccgcca aaaaacggag cctcatcctg
     4201 agaagcaaca atggaagtgg gggagacggg agggaggaga gggctgagag ttcccctggc
     4261 ctcttacgga ggatggcctc accccagagg gccagaccca ggggtagtgg ggagccaccc
     4321 ccacccccac ccttggagcc acctgctgca tgcatggggt tgtctacaca gtcatccctg
     4381 cccagtgctg tgaggaccaa ggtgctgcca ccgcgaaagg gccgcggcct caagctggag
     4441 gccatagtac agaagatcac ctcacctggg ctcaagaaac tcgcatgcag agtggcaggg
     4501 gcccctcctg ggacaccccg gagcccagcc ctgcctgaga gacgtccagg gggcagtcca
     4561 gccggggcgg aagagggttt aggaggaatg gggcaaatgc taccagcagc ttccggagct
     4621 gacccattgt gcaggaaccc agccagcagg tccctaaaag gtaaactctt gaacagtaag
     4681 aagctgtcct ctgctgctga ctgccccaaa gctgaggcct tcatgtcccc ggagaccctg
     4741 ccatcactag ggactgcccg agcaccgaag aaaaggagcc ggaaaggcag aactgggacc
     4801 ttgggaccct ccaaaggtcc gttggagaag cggccatgtc cgggccagcc tctgctcctc
     4861 gctccccacg acagggccag cagcactcag ggcggaggcg aggacaactc cagtggagga
     4921 ggcaagaagc caaagacaga ggagctggga ccggcctccc agccccctga aggccggccc
     4981 tgccagcccc agacaagggc gcagaagcag ccgggccaag ccagctacag cagctattcc
     5041 aagcggaagc gcctcagccg aggccggggg aagaccgccc acgcttcacc ctgtaaggga
     5101 cgtgccactc ggagaaggca gcagcaggta ctgcccctgg atcctgcaga gcctgaaatc
     5161 cgactcaaat acatttcctc ttgcaagagg ctgcgggcag acagccgcac cccagccttc
     5221 tcgccctttg tgcgggtgga gaagcgagat gcttacacca ccatatgcac tgtcgtcaac
     5281 tccccggggg atgagccgaa gcctcactgg aagccatcct cctctgctgc ctcctcctcc
     5341 acctcttcct cctccttaga accagctggg gcttctctga ccacattccc tggaggctct
     5401 gtgctgcagc agaggccctc cctgcccctc tcctccacca tgcatctggg gcctgtggtg
     5461 tccaaggccc taagtacctc ttgccttgtc tgctgcctct gccaaaaccc ggccaatttc
     5521 aaggaccttg gggacctctg tggcccctac taccctgaac actgcctccc caaaaagaag
     5581 ccaaaactca aggagaaggc gcggctggag ggcaccttgg aggaggcctc tctgcctctc
     5641 gagagaacac tcaaaggcct ggaatgttcg gccagcacca cggctgccgc ccctaccaca
     5701 gccactatca ctacccccac ggccctgggg agactgtcca ggcccgatgg cccagctgac
     5761 cctgccaagc agggccccct gcgcaccagt gcccggggcc tgtcacggcg gctgcagagt
     5821 tgctattgct gtgatggtca gggggacggg ggtgaggagg tggcccaggc tgacaagagc
     5881 cgcaaacatg aatgcagcaa agaggcccct acagaacctg gtggggacac ccaggaacac
     5941 tgggtccatg aggcctgtgc tgtgtggacc agcggggtgt acctggtggc cgggaagctc
     6001 tttgggctgc aggaggccat gaaggtagct gtggacatgc cgtgtaccag ctgtcacgag
     6061 cccggggcga ccatctcgtg ctcctataaa ggatgtatcc acacctacca ctacccatgt
     6121 gccaatgaca caggttgcac gttcattgag gagaatttta ctttgaagtg ccccaaacat
     6181 aagaggctgc cgttgtaatc cccgtgtggc cgaaactccg aggaagaaga gctgcgccca
     6241 cagccggtcc ttgatcccat ccagggtcta ggttccggct gccttgggcg ctggcgtgag
     6301 gcctaggttg cgaagaaaac cggggccagg cttggcgaag gcaggccagg gagtggccag
     6361 acccagggca caatgtctca ggcggggggc aagtcccctg caagttctga aaaagacgtg
     6421 gcatgcaagc tgtgcccctg ggaagaggct aggctgctgg ctcagtggac gacgtggggc
     6481 agacccaagc ctttcttaga ggcccagcgg cgggggacat ggctcagcac ttggcatgga
     6541 tctgcccaag atcgtggcag cctgggctca ggccagtcta tccttgatgc gggctggcct
     6601 ggggtggcgc cctatggctt ctgtttgtcc cctttccagt cttccacccc actgttggag
     6661 ccccgtctgg aagcctgagg agactgggcc tggctaccct ctagcagatg tgcagctgtc
     6721 ccagacaaaa caccaacatg ggattcaggg actgccactc agctcactcg gctcataggc
     6781 ggagacagtg ctagattcgt gtacaaacct gtgtacccct ctatatatat gttacataga
     6841 atgtatatat gttgggaaca tgctcgcttc tgtgtgtcgc tgctgtgcgt cgtgtgctcc
     6901 acagcacaga gccctaacct ggccttggct ggggtcgggg ccaaagtgat gccccttccc
     6961 cgagcaacta ccaccatcac caccaccacg gccagccccc acctgtccgt ttgtgtcctc
     7021 agctctgtcc acgctttaat aggcctgatg cagccccttc tccctgcaac gttctgtaca
     7081 tatgactgta aaatggtaaa cgtgtgtatt atatctggcc tcgttatata gtgtatatat
     7141 atgtatacat atacatatat ataatatata tgaagactgt aaatgttaag acaactagtg
     7201 ttcttattag tatattgctt cacactgaag attgtgtgta tcgagctgtt tctaaaagat
     7261 gtttattttc cttaagagtt aaaaaaaaaa aaaacagtca ttgcattcag aaaaaaaaaa
     7321 gtcaataaag ataccacgat tgttttgg
//
