LOCUS       NM_001346522            3739 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus RPA1 related single stranded DNA binding protein,
            X-linked (Radx), transcript variant 2, mRNA.
ACCESSION   NM_001346522 XM_006528474
VERSION     NM_001346522.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3739)
  AUTHORS   Okamura,E., Tam,O.H., Posfai,E., Li,L., Cockburn,K., Lee,C.Q.E.,
            Garner,J. and Rossant,J.
  TITLE     Esrrb function is required for proper primordial germ cell
            development in presomite stage mouse embryos
  JOURNAL   Dev Biol 455 (2), 382-392 (2019)
   PUBMED   31315026
REFERENCE   2  (bases 1 to 3739)
  AUTHORS   Dungrawala,H., Bhat,K.P., Le Meur,R., Chazin,W.J., Ding,X.,
            Sharan,S.K., Wessel,S.R., Sathe,A.A., Zhao,R. and Cortez,D.
  TITLE     RADX Promotes Genome Stability and Modulates Chemosensitivity by
            Regulating RAD51 at Replication Forks
  JOURNAL   Mol Cell 67 (3), 374-386 (2017)
   PUBMED   28735897
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL691424.7.
            
            On Oct 18, 2016 this sequence version replaced XM_006528474.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK171459.1, SRR1660811.133538.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-772               AL691424.7         69233-70004
            773-915             AL691424.7         81507-81649
            916-1108            AL691424.7         83910-84102
            1109-1217           AL691424.7         95558-95666
            1218-1309           AL691424.7         95867-95958
            1310-1432           AL691424.7         96061-96183
            1433-1537           AL691424.7         100411-100515
            1538-1699           AL691424.7         102012-102173
            1700-1860           AL691424.7         103100-103260
            1861-2036           AL691424.7         103952-104127
            2037-2098           AL691424.7         120584-120645
            2099-2389           AL691424.7         131802-132092
            2390-2557           AL691424.7         133893-134060
            2558-3739           AL691424.7         142269-143450
FEATURES             Location/Qualifiers
     source          1..3739
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 61.35 cM"
     gene            1..3739
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /note="RPA1 related single stranded DNA binding protein,
                     X-linked"
                     /db_xref="GeneID:102871"
                     /db_xref="MGI:MGI:2147848"
     exon            1..772
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..2679
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /note="isoform 2 is encoded by transcript variant 2;
                     likely orthologue of H. sapiens Chromosome X open reading
                     frame 57 (CXorf57); uncharacterized protein CXorf57
                     homolog; RPA-related protein RADX"
                     /codon_start=1
                     /product="RPA-related protein RADX isoform 2"
                     /protein_id="NP_001333451.1"
                     /db_xref="CCDS:CCDS85808.1"
                     /db_xref="GeneID:102871"
                     /db_xref="MGI:MGI:2147848"
                     /translation="MSGESGQPQPGPSHAGLYLEHPERDQAGVPGGVIRRADSQRRRS
                     WIQKVIEQITGSPRQCVTLSEVVPVTVLAVQRYLLEDEPRDTVPKPPLYCYDVTISDG
                     VYQEKCYLDPSLNFLVYQNILKVGIEMRISRVSCLYNEKRLGQGILCIDKVHCGESLD
                     VISVETPFRNRAHEEKPERPLRGGKSHYLALWNNEDPYGDIWKTNKQPEEFNFNNIKI
                     ISLSHLELTWNSRKNFPALLVRVLHKSKLRYYGKPNKKMIEPYQTYLEVADSSGMVSV
                     ILWNALCPEWYKSLRVGLVLLLQDYTVKKSYPLRIQPDPADPQMKLISTMEICLNLRD
                     PPTNIVIIPEKQLKSEWKLPKLINRFITRSELDDMPEKSICDVIGLLSFVGRVQRSKK
                     KENSEDFWSYRWIHITDGTSEQPFIVQLFSTSQPEVFENIYPMTYFVCTQLKVVRNNS
                     QVPKLLYLTTTNESRALTTGHRGLPYTYDTKAKKIIQWIKTKTNLEAKNTVIGGYYPY
                     PPVPETFSKYSRFIKAESLLTTISEVKKVIEDLQYREQKRIAIQGIITAIKYIPYKHS
                     AGSAPAPEAFWNASRPSTSQAAGKEDHCHERGSKRSQDDRPMGSQHFQYTSKVLSLCA
                     KRKILQGPSANPVPVPQPHSSAQMKGSKHNTPSQESSTAYTTGKSRRITNDRWESQLW
                     QDKKFSLRDHLHYGHVDPESIPRKFILEHEKFLTQQFNSQPAKYIPPEGKPPKLDEFQ
                     SARSLGHFEVTILGLNHEIAIDVAFLPMYSPEDVQASQIDTFLTCMNFSCVYPPAAPL
                     SGRLPDPKAVAGDIVKAAADLDRVHIIGILDICNLGNNKVEVCLQKIYTPE"
     exon            773..915
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1108
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1217
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1218..1309
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1432
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1537
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1699
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1700..1860
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..2036
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2037..2098
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2099..2389
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2557
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2558..3739
                     /gene="Radx"
                     /gene_synonym="D330045A20Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaccagtccg tgccaacagc tttgcgcggc tgtctagagc gtcttttctc cgggtttttg
       61 agcagggaaa gtaaggtttt tttttttttt tttttttttg gagtgcaagg agttcgcggt
      121 taccccacaa tgtcgggtga gtcgggtcag cctcagccgg gaccctcgca cgctggtctc
      181 tacttggagc accccgaaag ggatcaggct ggggtcccag gtggagtgat acgaagagct
      241 gatagccaga ggcgcaggtc ctggatccaa aaggttattg agcaaataac aggttcccct
      301 agacagtgtg tcaccctctc ggaagtggtg cctgtcactg tactggctgt ccaaagatac
      361 cttttagagg atgagccacg ggatacagtg cccaagcctc ccctttactg ctatgatgtg
      421 acaatctcag acggggtgta ccaggagaag tgctacttag accccagctt aaactttctc
      481 gtttatcaaa atattcttaa agttggcata gagatgagaa tttccagagt ctcgtgcctt
      541 tacaacgaga aaagattggg ccagggaatc ctgtgcatag ataaggtcca ctgtggggag
      601 tccctagatg tcatttctgt agaaactcca tttagaaaca gagcgcatga ggaaaagcca
      661 gagaggcctt taagaggggg caagagtcac tacctggctc tgtggaataa cgaagatccg
      721 tacggagata tttggaagac caacaagcaa cctgaggaat tcaattttaa caacatcaaa
      781 ataatctctc tctctcatct tgagttgact tggaatagca gaaagaattt tcctgccttg
      841 cttgtaagag tcctgcataa atcaaaactg cgatactatg gaaaacctaa taaaaagatg
      901 attgagccat atcagaccta tttggaggtt gctgacagct cgggcatggt gtcagtgatt
      961 ctgtggaatg ctctgtgtcc agagtggtat aaaagtttga gagtgggctt ggttcttctg
     1021 cttcaagatt atactgtgaa gaagagctat ccattaagaa tccagcctga ccctgcagat
     1081 ccacagatga aactcatttc tactatggaa atttgcctga atcttcgaga tccaccaact
     1141 aacatagtta tcattccaga aaagcaattg aaatcagaat ggaaattgcc aaaactaatt
     1201 aaccgattca tcacaagatc agaactagac gatatgccag aaaaaagcat ctgtgatgta
     1261 attggtttgt tatcctttgt agggagggtg caacggtcaa agaagaaaga gaacagtgaa
     1321 gacttttggt cataccgctg gattcacatc actgatggga cttcagagca accattcata
     1381 gtgcagctgt tctccacatc gcagccagaa gtctttgaaa atatttaccc aatgacatat
     1441 tttgtgtgca cccagttgaa agtcgttaga aataacagcc aagtacctaa gctgctttat
     1501 cttaccacta caaatgaaag cagagcactt actactgggc atagaggcct gccatataca
     1561 tacgatacca aggcaaaaaa aattattcag tggattaaaa cgaagactaa tttggaagca
     1621 aagaacacgg ttattggtgg atattacccc tatccaccag tgccagagac attttccaag
     1681 tacagtcgct ttattaaagc tgagtcactc ttgacaacaa taagtgaagt aaagaaggtg
     1741 attgaagact tgcagtatag ggaacaaaag cgcattgcaa ttcaggggat aattactgct
     1801 ataaagtaca tcccctataa gcactcagcc ggaagtgccc cagcaccaga agcattctgg
     1861 aatgctagcc gtccctcaac atctcaagca gctgggaaag aagatcattg tcatgaacga
     1921 ggtagtaaaa ggtcccaaga tgacagacca atggggtctc agcattttca atatacctcc
     1981 aaggttttga gtctctgtgc aaaaagaaaa attcttcaag gcccaagtgc taatccggtt
     2041 cctgttcctc agccgcattc ttctgcacag atgaaaggaa gcaaacacaa cacaccaagt
     2101 caagaaagtt caactgctta taccacaggg aagtccagaa gaatcacaaa tgatcgatgg
     2161 gagagtcagc tgtggcaaga taagaagttt agcttgagag accacctaca ttatggtcac
     2221 gtggatcctg aaagtattcc acggaaattt attttggagc atgaaaagtt tctcactcag
     2281 cagtttaatt ctcagcctgc aaaatacata ccaccagaag gaaagccccc caaacttgat
     2341 gaatttcaga gcgcccgaag ccttggacat tttgaagtaa ccatcctagg tttgaaccat
     2401 gagattgcga tcgatgttgc atttctacct atgtattctc cagaagatgt tcaagcatcg
     2461 caaatagata catttttgac ttgcatgaat ttcagctgtg tgtatccacc agcagcacct
     2521 ctcagtggaa ggttgccaga tcccaaggca gttgcaggtg atattgtaaa ggcagcagct
     2581 gacctggata gagtccacat cattggtatc ttggatatct gtaatttggg taacaataaa
     2641 gtggaagtct gtttgcagaa aatttatact ccagaatagg cttcttaaag attagtagag
     2701 aaagtaatta caggttatat acagtatact gctttagaga gaatttgtta atttgcttgg
     2761 tattttcatc agaatattac atgacctgga aagttaagtg gttttcagtt catcttgtat
     2821 ttggcactct cacttcatat tagattcatt attgaaaaaa agtcatcaag tcaattttat
     2881 gtgtcaaaaa ttatttcact tgtatgtgac tattatctta acttgtaaca atttatgttt
     2941 tacagttcct tttacaaagt gtatttttac tccagtgtgt cttggcttac acaatttaac
     3001 agctttctga ttttattcac atacagtgat gaatcttgca ttgcaaattc aaagtctaag
     3061 ttaacagtct cctaaagtga ccacctacat ttcttataat ccaggtagtt cctgtcatgt
     3121 ccacacacac atggattgta gtgatccaat tgccccagtc tccctgcatt tgctattaag
     3181 tgaatatgct gaactgtcat aaaatttttt caacccttta ttgtgatttc caatgtcttg
     3241 aagttttaag tgttttgacc agtgtgtaat gttaaattca gaggctacag tatatctaca
     3301 ttcatgtggt gttcattggt aatttcagta tatgtaatgt gattttagac tgtgaaattt
     3361 tatctcacat taatatctga agtgcttgta ttaaaagtaa agaaaggtaa ctaagggaat
     3421 ttgtttcagt ctggttctcc acttactata ctgtgttttc aaggtaaatg gtcactctac
     3481 atttataaac acaggtctga ttgtacttga ggtataagaa aatctatgag gaaacaagat
     3541 ttccctataa ccctataatt ttgtgatgtc atgtgctgta cagttttaat gtggtgagca
     3601 gcctaagaac ttaaaggtgt acggtatttt gtttataaag atgttcagat ttcttagtaa
     3661 ctgtattaaa tggttaatta aaactgtgaa tttttgtgta actagtttca gagtgttatt
     3721 aaatatgata aaatgcagt
//
