LOCUS       NM_001111118            3199 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus RAD51 associated protein 2 (Rad51ap2), mRNA.
ACCESSION   NM_001111118 XM_001477981
VERSION     NM_001111118.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3199)
  AUTHORS   Ma,H., Li,T., Xie,X., Jiang,L., Ye,J., Gong,C., Jiang,H., Fan,S.,
            Zhang,H., Shi,B., Zhang,B., Jiang,X., Li,Y., Zhou,J., Xu,J.,
            Zhang,X., Hou,X., Yin,H., Zhang,Y. and Shi,Q.
  TITLE     RAD51AP2 is required for efficient meiotic recombination between X
            and Y chromosomes
  JOURNAL   Sci Adv 8 (2), eabk1789 (2022)
   PUBMED   35020426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC139207.10 and CT009765.9.
            
            On Feb 9, 2019 this sequence version replaced NM_001111118.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363660.1160395.1,
                                           SRR7652917.265031.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2761              AC139207.10        243074-245834
            2762-2836           CT009765.9         162306-162380       c
            2837-3199           CT009765.9         158814-159176       c
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 5.58 cM"
     gene            1..3199
                     /gene="Rad51ap2"
                     /gene_synonym="EG209550"
                     /note="RAD51 associated protein 2"
                     /db_xref="GeneID:209550"
                     /db_xref="MGI:MGI:3644580"
     exon            1..2761
                     /gene="Rad51ap2"
                     /gene_synonym="EG209550"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..2955
                     /gene="Rad51ap2"
                     /gene_synonym="EG209550"
                     /codon_start=1
                     /product="RAD51-associated protein 2"
                     /protein_id="NP_001104588.1"
                     /db_xref="CCDS:CCDS49029.1"
                     /db_xref="GeneID:209550"
                     /db_xref="MGI:MGI:3644580"
                     /translation="MSLSRPAWPAGPAWPVSSEPPPEDPAAASPSSKRRRLKEPDGGV
                     SEAGWPLLVVPRLSEVEKVWEWSLRPFTAFLIPKSPGSSAGGKQSCDLGCRDRTFQAH
                     SCWQSGILGCSRAPRRSCEAGLQDREVQGVRLGDQAEVSHAPPNSPMPYVQGVKQEPE
                     ELPEKETILKEKNSVREPGNPFLDVPFSEETKSALHEIKDRCKVDSVITSEKKENVSS
                     STLKISKFQNQACLESAKPSYFRDSNTKNFFEFPRDLNSNMSFVYLKETAKKKNDKIV
                     AYVRDFTNIFSSQNRPNAKKQKLQDDKKNVYVENDFSDYSESYHQSLTIEGKIDLINL
                     NYYRHSSIECDVRDSKKNFTLTLEVANCEGTERNQEYYIPTRQEFQNLDCDRSILKIK
                     KENCWRIKKIRIICENNMILENNIVSLHDNFDSFIRKKEKKKDDRESEEGCIFKYIVN
                     LNYLKNIKKERYIVYLTKMLTSLRLLECNTKSTAKKRKLFKTEHVLQRVKKQNINSLT
                     MTTKIFLIYKLCENVPPLMGFDNTEELSLTKESSYESTRCAKLLLNMKNLDYYSFGID
                     GTHVESDPLFIQNNCGHINEKYYESSMYNQDLDTVRKWKHKTIHFIFKSIFEDVFNVR
                     QLCTLLSQNTSHSDQINAMAITLKISLENLLSETEGKIYDFVLKREMKVTKSSSSFQA
                     HNAIDTEKEEDSFPTMDGMSSVQSASLVSKSINMEETKSLNQNNRTSTKEDGGILQES
                     ELANSKHFHPKNESALYANHQFESDSSGENNECFQGLTATCLSTETLPIAEEFEMKSK
                     FDLVLEELRMFHEISKENEIPSTRMTNNRKENYFGESNDVKEARMEIGKKLEMVETNT
                     RNAPFLSCDVKAGLNKHKRHQSLFNWKMLPTHGGQAVPNECWPRSEERSLHSTPEEDY
                     KKHLPKSPTFSPDEYKNETLLKGGSHFSHGISRVQPLKTCSRPIRVGLSRRARLKQLH
                     PYLK"
     exon            2762..2836
                     /gene="Rad51ap2"
                     /gene_synonym="EG209550"
                     /inference="alignment:Splign:2.1.0"
     exon            2837..3199
                     /gene="Rad51ap2"
                     /gene_synonym="EG209550"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3171..3176
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rad51ap2"
                     /gene_synonym="EG209550"
                     /note="hexamer: ATTAAA"
     polyA_site      3197
                     /gene="Rad51ap2"
                     /gene_synonym="EG209550"
                     /note="major polyA site"
ORIGIN      
        1 gacagatgct cctggtaggc gctcatgtct ctgtcgcgcc ccgcgtggcc tgcagggcct
       61 gcctggcctg tctcctcaga accgcctcct gaggaccccg ctgcggcgtc ccccagcagc
      121 aagcggcggc gtctgaagga gcctgacggc ggagtctctg aggcgggatg gccgctgctt
      181 gtggtgcctc gcttgtctga ggtagaaaaa gtctgggagt ggtcgctcag acccttcaca
      241 gcgttcctca ttccaaagag cccggggagc tcagccggtg ggaagcagtc gtgtgacctg
      301 ggatgtcggg acagaacatt ccaggcgcac agctgttggc agtctggaat cttaggttgt
      361 tctagggctc caagaaggtc ttgtgaagca ggactgcagg acagggaggt tcagggggtg
      421 cgccttggtg accaagcaga agtgagtcat gctccaccca atagccccat gccctatgtc
      481 caaggagtca aacaggagcc tgaagaactt cctgagaagg aaactattct gaaagaaaag
      541 aattctgtga gagagccagg aaacccattt ctagatgtac cattttctga ggaaactaag
      601 tcagcattac atgaaattaa agacagatgt aaagttgaca gtgttataac ctctgagaaa
      661 aaagaaaacg tttcatcgtc tacactaaaa atatcaaaat ttcaaaacca ggcctgcttg
      721 gaaagtgcca aacctagcta ttttagagat agcaacacaa aaaatttctt tgagtttcca
      781 agggatttaa atagcaacat gtcctttgtc tatttaaagg aaacagcaaa gaaaaaaaat
      841 gacaaaattg tggcatatgt tagggatttc acaaacattt tctcgtccca aaatagaccg
      901 aatgctaaga aacaaaagtt acaggatgat aaaaaaaatg tatatgtgga aaatgatttt
      961 tctgactatt ctgaaagtta ccaccagtca ctcaccattg aagggaaaat agacttgatc
     1021 aatttaaact actataggca cagtagtatt gagtgtgatg taagagactc taaaaagaat
     1081 ttcactctaa cactagaagt tgcaaattgc gagggaacag aaaggaatca agagtattac
     1141 atacctacca gacaagaatt tcaaaacttg gactgtgaca gatctatttt gaaaataaaa
     1201 aaggaaaatt gttggagaat aaaaaaaatt aggattattt gtgagaataa tatgattctg
     1261 gaaaacaata tagtttcttt gcatgataac tttgattctt tcataagaaa gaaagaaaag
     1321 aagaaagatg atagggaatc agaagaggga tgcattttca aatatatagt gaatttgaat
     1381 tatttgaaaa atattaaaaa ggaaagatat attgtgtatc taacaaagat gttaacttct
     1441 ttaagactgt tagaatgtaa tacaaaatct acagcaaaga aaaggaaact atttaaaacg
     1501 gaacatgttc ttcaacgggt taagaaacaa aacatcaatt ctcttactat gacaactaaa
     1561 atttttctaa tttacaaact atgtgaaaat gttccccctt taatgggttt tgataacacg
     1621 gaagaacttt ctttgacaaa agaatctagt tatgagagta caagatgtgc caaactacta
     1681 ctaaatatga aaaatttgga ttattatagt tttggtattg atggcacaca tgtggagtct
     1741 gatcctctat ttatacagaa taactgtgga catattaatg aaaaatatta tgagagtagt
     1801 atgtataatc aagatttaga tactgtaaga aaatggaagc ataagaccat tcactttatt
     1861 tttaagtcga tatttgaaga tgtctttaat gttagacaac tgtgcacatt gttaagccaa
     1921 aatacatcac acagtgacca gattaatgct atggcgataa ctctgaagat cagcttggag
     1981 aatctgttaa gtgaaacaga agggaaaata tatgattttg ttttgaagag agaaatgaag
     2041 gtcacaaaaa gttcaagtag ttttcaagcc cataacgcta ttgacactga gaaggaagag
     2101 gatagttttc ccacaatgga cggaatgtct tcagtgcagt cagcttcgct agtgagtaag
     2161 agcataaata tggaagaaac taaatctctt aatcaaaata atagaactag cacaaaagag
     2221 gatggaggta ttttgcaaga aagtgagtta gctaattcaa agcattttca tccaaagaat
     2281 gagtctgcat tatatgctaa tcatcaattt gaaagtgact caagtgggga gaacaatgaa
     2341 tgttttcagg gtttaactgc tacatgttta tcaacagaaa ctctgccaat agcagaagag
     2401 tttgagatga agagcaaatt tgatttagta cttgaagaac ttcgaatgtt tcatgaaatt
     2461 agtaaggaaa atgaaattcc aagtaccagg atgacaaaca ataggaaaga aaattacttt
     2521 ggagaaagta atgatgttaa agaggcaaga atggagatag gaaaaaaact ggaaatggtt
     2581 gaaaccaaca caagaaatgc accttttttg tcctgtgatg tgaaggcagg tctcaacaaa
     2641 cataaaaggc accaaagttt atttaactgg aaaatgctac ctactcatgg aggacaggca
     2701 gttcccaatg agtgttggcc aagatcagag gaacgatcac tccattctac tcctgaggaa
     2761 gattataaga aacatttacc taaaagccct actttttccc ctgatgaata taaaaatgaa
     2821 actttattga agggaggcag tcatttttcg catgggattt ccagagtaca gcctcttaag
     2881 acatgcagtc gtccaattag ggttggcttg tcaagaagag ctaggctgaa acagcttcat
     2941 ccttacctga aatgaatgag ttgtaaggac ttacaagaag cttctggact ttaccagttc
     3001 agcatgtcta ggaatgattt acttgttgct ttgtataagt gttttcctcc agctgcagat
     3061 tttgtgttgt atttttttaa gtgtagagag gttcttttct gtataaatta tttaattacc
     3121 ttgaaaggaa aacttttact gctatttcat gtcatatgat caagatacac attaaagtat
     3181 ttttatgatc atataaacc
//
