LOCUS       NM_009011               3827 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus RAD23 homolog B, nucleotide excision repair protein
            (Rad23b), mRNA.
ACCESSION   NM_009011
VERSION     NM_009011.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3827)
  AUTHORS   Nedomova,M., Haberecht-Muller,S., Moller,S., Venz,S.,
            Prochazkova,M., Prochazka,J., Sedlak,F., Chawengsaksophak,K.,
            Hammer,E., Kasparek,P., Adamek,M., Sedlacek,R., Konvalinka,J.,
            Kruger,E. and Grantz Saskova,K.
  TITLE     DDI2 protease controls embryonic development and inflammation via
            TCF11/NRF1
  JOURNAL   iScience 27 (10), 110893 (2024)
   PUBMED   39328932
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3827)
  AUTHORS   Aiello,F.B., Guszczynski,T., Li,W., Hixon,J.A., Jiang,Q.,
            Hodge,D.L., Massignan,T., Di Lisio,C., Merchant,A., Procopio,A.D.,
            Bonetto,V. and Durum,S.K.
  TITLE     IL-7-induced phosphorylation of the adaptor Crk-like and other
            targets
  JOURNAL   Cell Signal 47, 131-141 (2018)
   PUBMED   29581031
REFERENCE   3  (bases 1 to 3827)
  AUTHORS   Zhang,Y.J., Gendron,T.F., Grima,J.C., Sasaguri,H., Jansen-West,K.,
            Xu,Y.F., Katzman,R.B., Gass,J., Murray,M.E., Shinohara,M.,
            Lin,W.L., Garrett,A., Stankowski,J.N., Daughrity,L., Tong,J.,
            Perkerson,E.A., Yue,M., Chew,J., Castanedes-Casey,M., Kurti,A.,
            Wang,Z.S., Liesinger,A.M., Baker,J.D., Jiang,J.,
            Lagier-Tourenne,C., Edbauer,D., Cleveland,D.W., Rademakers,R.,
            Boylan,K.B., Bu,G., Link,C.D., Dickey,C.A., Rothstein,J.D.,
            Dickson,D.W., Fryer,J.D. and Petrucelli,L.
  TITLE     C9ORF72 poly(GA) aggregates sequester and impair HR23 and
            nucleocytoplasmic transport proteins
  JOURNAL   Nat Neurosci 19 (5), 668-677 (2016)
   PUBMED   26998601
  REMARK    GeneRIF: data demonstrate that sequestration and impairment of
            nuclear HR23 and nucleocytoplasmic transport proteins is an outcome
            of, and a contributor to, poly(GA) pathology.
REFERENCE   4  (bases 1 to 3827)
  AUTHORS   Hamazaki,J., Hirayama,S. and Murata,S.
  TITLE     Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated
            Proteins and Cellular Homeostasis
  JOURNAL   PLoS Genet 11 (7), e1005401 (2015)
   PUBMED   26222436
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3827)
  AUTHORS   Cattoglio,C., Zhang,E.T., Grubisic,I., Chiba,K., Fong,Y.W. and
            Tjian,R.
  TITLE     Functional and mechanistic studies of XPC DNA-repair complex as
            transcriptional coactivator in embryonic stem cells
  JOURNAL   Proc Natl Acad Sci U S A 112 (18), E2317-E2326 (2015)
   PUBMED   25901318
REFERENCE   6  (bases 1 to 3827)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 3827)
  AUTHORS   Ng,J.M., Vrieling,H., Sugasawa,K., Ooms,M.P., Grootegoed,J.A.,
            Vreeburg,J.T., Visser,P., Beems,R.B., Gorgels,T.G., Hanaoka,F.,
            Hoeijmakers,J.H. and van der Horst,G.T.
  TITLE     Developmental defects and male sterility in mice lacking the
            ubiquitin-like DNA repair gene mHR23B
  JOURNAL   Mol Cell Biol 22 (4), 1233-1245 (2002)
   PUBMED   11809813
REFERENCE   8  (bases 1 to 3827)
  AUTHORS   Liu,Z., Li,P., Kocabas,A., Karsi,A. and Ju,Z.
  TITLE     Microsatellite-containing genes from the channel catfish brain:
            evidence of trinucleotide repeat expansion in the coding region of
            nucleotide excision repair gene RAD23B
  JOURNAL   Biochem Biophys Res Commun 289 (2), 317-324 (2001)
   PUBMED   11716474
REFERENCE   9  (bases 1 to 3827)
  AUTHORS   Park,H., Suzuki,T. and Lennarz,W.J.
  TITLE     Identification of proteins that interact with mammalian
            peptide:N-glycanase and implicate this hydrolase in the
            proteasome-dependent pathway for protein degradation
  JOURNAL   Proc Natl Acad Sci U S A 98 (20), 11163-11168 (2001)
   PUBMED   11562482
REFERENCE   10 (bases 1 to 3827)
  AUTHORS   van der Spek,P.J., Visser,C.E., Hanaoka,F., Smit,B., Hagemeijer,A.,
            Bootsma,D. and Hoeijmakers,J.H.
  TITLE     Cloning, comparative mapping, and RNA expression of the mouse
            homologues of the Saccharomyces cerevisiae nucleotide excision
            repair gene RAD23
  JOURNAL   Genomics 31 (1), 20-27 (1996)
   PUBMED   8808275
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY140385.1, AK150089.1, AK142280.1 and BE989853.1.
            
            On Apr 2, 2008 this sequence version replaced NM_009011.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK142280.1, AK150089.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 BY140385.1         1-8
            9-2779              AK150089.1         1-2771
            2780-3795           AK142280.1         2757-3772
            3796-3827           BE989853.1         1-32                c
FEATURES             Location/Qualifiers
     source          1..3827
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 29.7 cM"
     gene            1..3827
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /note="RAD23 homolog B, nucleotide excision repair
                     protein"
                     /db_xref="GeneID:19359"
                     /db_xref="MGI:MGI:105128"
     exon            1..386
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     CDS             321..1571
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /note="RAD23b homolog; XP-C repair-complementing complex
                     58 kDa protein"
                     /codon_start=1
                     /product="UV excision repair protein RAD23 homolog B"
                     /protein_id="NP_033037.2"
                     /db_xref="CCDS:CCDS18194.1"
                     /db_xref="GeneID:19359"
                     /db_xref="MGI:MGI:105128"
                     /translation="MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQ
                     KLIYAGKILSDDTALKEYKIDEKNFVVVMVTKPKAVTTAVPATTQPSSTPSPTAVSSS
                     PAVAAAQAPAPTPALPPTSTPASTAPASTTASSEPAPAGATQPEKPAEKPAQTPVLTS
                     PAPADSTPGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNP
                     DRAVEYLLMGIPGDRESQAVVDPPPQAVSTGTPQSPAVAAAAATTTATTTTTSGGHPL
                     EFLRNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQE
                     AGSQGGGGGGGGGGGGGGGGGIAEAGSGHMNYIQVTPQEKEAIERLKALGFPEGLVIQ
                     AYFACEKNENLAANFLLQQNFDED"
     exon            387..468
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     exon            469..548
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     exon            549..817
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     exon            818..873
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1001
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1137
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1265
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..1457
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..3811
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2318..2323
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /note="hexamer: AGTAAA"
     polyA_site      2336
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /note="major polyA site"
     regulatory      2763..2768
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /note="hexamer: ATTAAA"
     polyA_site      2786
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /note="major polyA site"
     regulatory      3074..3079
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /note="hexamer: AATAAA"
     polyA_site      3100
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
     regulatory      3787..3792
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
                     /note="hexamer: TATAAA"
     polyA_site      3811
                     /gene="Rad23b"
                     /gene_synonym="0610007D13Rik; HR23B; mHR23B; p58"
ORIGIN      
        1 tggtggggga ggggtcacgt ctcggcgagt cacggtgatg gcggccacca tcctgtggtg
       61 aggtagcggg ttctctgcgt ctctcgggga gtccctcgcg cctcctgcgg gcccagtggc
      121 tggcgcgtga ggaagcaccg cgggtcgagc ttaccgggaa agccgcggga gcgagcggcg
      181 gcgcggccag gggagacgcg gggcccgggg tgagtgcgac tccgggcgaa tgtgacaagc
      241 ccccccaccc ccaccgcctt cctcccgaga gcgcgaggat cgcggccacc ccggggcggc
      301 caggccccgg cttaggcacc atgcaggtca ccctgaagac ccttcagcag cagaccttca
      361 agatcgacat cgacccggag gagacggtaa aggcattgaa agagaagatt gaatctgaaa
      421 aggggaaaga tgcctttccg gtagcaggtc agaagttaat ttatgcaggc aaaatcctca
      481 gtgatgatac tgctctcaaa gaatataaaa ttgatgagaa aaactttgtg gtggttatgg
      541 tgacaaaacc caaagcagtg accacagcag tgccagctac aacccagcca tcaagtactc
      601 ccagccccac tgcagtcagt tcttccccag cagtggctgc ggcccaggct ccagctccca
      661 cccctgctct gcctcccact tccactcctg cctccactgc tccagcctcc actacagcct
      721 cttctgaacc cgcacctgct ggtgccactc agcctgagaa acctgcagaa aagccagccc
      781 agacaccagt gcttactagc ccagcaccag ctgacagtac accaggagat tcttcccggt
      841 caaatctttt tgaagatgca acaagtgccc ttgtgacagg tcagtcttat gagaatatgg
      901 taactgagat catgtcaatg ggctatgaac gagaacaagt aattgcagcc ctgagagcca
      961 gcttcaacaa ccctgacaga gctgtggaat atcttctaat gggaatccct ggagatagag
     1021 aaagtcaggc tgtggttgac cctcctcctc aggctgtgag tactggaact cctcagtctc
     1081 cagcagtagc tgcagctgca gcaaccacga cagcaactac aacaaccact tctggaggcc
     1141 acccccttga atttttacgg aatcagcctc agtttcaaca gatgagacaa attatccagc
     1201 agaatccttc tttgctgcca gccttgctac agcagatagg tcgggagaac cctcagctgc
     1261 tgcagcaaat tagccaacac caggagcatt ttattcagat gctgaatgaa ccagttcagg
     1321 aagcaggcag tcaaggtgga ggaggtggtg gcggaggagg cggtggcgga ggaggcggtg
     1381 gaggaattgc agaagctgga agtgggcaca tgaattacat tcaagtaaca cctcaggaga
     1441 aagaagctat agaacggtta aaggcattag gatttcctga aggacttgtg attcaagcat
     1501 attttgcttg tgagaagaat gagaatctgg ctgccaactt tcttctacag cagaactttg
     1561 atgaagactg aagggatttt tttgtacctc acactcacac cagtgcatta cactaacctt
     1621 gttcactgga ttgtctgggg tgacttgggc tcatatccac aatatttggt atacggtagt
     1681 aggttggtgg gggtgggggt ggggagctag gatatagggc agggatacat acagttgcat
     1741 gtctgcttca attagcagat gctgcagatc cacacagtgt aaaatactat acaaccaaac
     1801 atccgccttt acaggtcgtt attcttctaa gcagtaggta acttttcctg ggtttcattc
     1861 tttctagtgt actagatcca gaaatttagt gtgatgccct gctttctctt ttctttgact
     1921 taacattggt ttctgaaaga atctttgcta cctagaacct gcagtctgtt ttatggcaac
     1981 actggataat ggctttttga aattgagggg gaaaaattgg agcatctgta aacagaaatg
     2041 ccaaattatt gatagtcatc gttgctgctt cacattagta tgagactgat gcagaaggaa
     2101 gcccattctt cgtgttcagt gctggggatg gggtggggac ttttcttaaa acgaaaataa
     2161 ttactgctat tttaaaatgt cttgattatt gaatgtgaga ccctctgaca tgatttgaga
     2221 agctgcacac ataggcagag tcattttcct gtttacattg tttgtttggg gaagattggt
     2281 aggggtctaa ttactgttca cttccttgtt gtattgcagt aaaagattta aaacaaccat
     2341 tgcatgtttg cttttgatgt atccctttgt gaaatcagca cttctggggc caatgaagaa
     2401 actgtgcagc attcactccc ctcccccctc ccctcccctc ccctccgtag agatgtgttt
     2461 gatcagcaag tcaggagtca aactgctgcc tttaaaaaaa cacacaaaaa gctgattcag
     2521 ttcaaaatta atgcaaatct ttcaaaactg ggtttctgat acttgtggat gtttttcttc
     2581 attagataag aatgtattac cattaaatcc attagtatta cattgctttc aaagagaagg
     2641 tgggtggaac tataattcag catcttttac tgcatttaaa gatgggagca aacttttgta
     2701 tggttgggag atgtggctgg aaagtacttt ggaaaatata caatcaagat atttcgtctc
     2761 atattaaaag agaaatctca atcacagtgt tggcttttat ttggattttg ctcatctcgg
     2821 tctttgtttg gaaactccct catcgacatt gctattggat tgtaaagagg ggcccagtat
     2881 cagtttgttg aatttgtcaa atcttttcct ggacataaat gagactattg aaggaagtaa
     2941 cgtcccaccg tcgtgatgct gtgtgagaag atggctttgc agacctcctg cgcagtctct
     3001 tgcactgtgt ccatcaccac ttggtgagga ctcttaaact ctctcctcat gtgcttatac
     3061 cctgttccat gaaaataaat gagaccatga ttttccttca tgatgtacca tgtttaactt
     3121 tcatgtatta ttctgcaaac ttggtaggct gttggatgtt atattgccca tgtgctttac
     3181 agtgggcaat gtgagatgtc tcagaatgaa acggtgcatc tttcagggca gaagagcagt
     3241 gggttgggga gaggggtaag gtccagtgga gtgggggaat gcttccattt gttctgccct
     3301 cccttactgc ccagaatgtt agcataaaac aacacaggaa gctgataaaa atagcagctg
     3361 ttgtttctct ttggaaagtg acagcagaag ttggtggcat gggacttttt gtccttggac
     3421 acaaacctgc agatcctagg agtaatagtt tcccccaagg acagcccagc ccatggacca
     3481 cttcttcctc agtggagata ccacacatga gtggagagat acgttagata gctttggtaa
     3541 atatctttaa tagaggtgac tattgaactg ttgaatcttg catttgcaca gtacaaggtg
     3601 taactagcat ctttagtatt tttattgttt tgctgctcta taggaaatat gaggaggctg
     3661 aatttatatt tgtaaattta ttttgccatc tttaagtcac atttttgttt cattgtttaa
     3721 aagtactgaa atgttccacc ctgttatgtt ttcctgtact agatggctag gattccagag
     3781 aattactata aagtattttc aacacacctg aaaaaaaaaa aaaaaaa
//
