LOCUS       NM_013862               3373 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus RAB GTPase activating protein 1-like (Rabgap1l),
            transcript variant 1, mRNA.
ACCESSION   NM_013862 XM_917205 XM_924757 XM_924760 XM_924762 XM_924763
            XM_924767 XM_924771 XM_924774
VERSION     NM_013862.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3373)
  AUTHORS   Qu,F., Lorenzo,D.N., King,S.J., Brooks,R., Bear,J.E. and Bennett,V.
  TITLE     Ankyrin-B is a PI3P effector that promotes polarized
            alpha5beta1-integrin recycling via recruiting RabGAP1L to early
            endosomes
  JOURNAL   Elife 5, e20417 (2016)
   PUBMED   27718357
  REMARK    GeneRIF: We demonstrate that AnkB binds to Rab GTPase Activating
            Protein 1-Like (RabGAP1L) and recruits it to PI3P-positive
            organelles, where RabGAP1L inactivates Rab22A, and promotes
            polarized trafficking to the leading edge of migrating fibroblasts.
            We further determine that a5b1-integrin depends on an AnkB/RabGAP1L
            complex for polarized recycling
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3373)
  AUTHORS   Villen,J., Beausoleil,S.A., Gerber,S.A. and Gygi,S.P.
  TITLE     Large-scale phosphorylation analysis of mouse liver
  JOURNAL   Proc Natl Acad Sci U S A 104 (5), 1488-1493 (2007)
   PUBMED   17242355
REFERENCE   3  (bases 1 to 3373)
  AUTHORS   Itoh,T., Satoh,M., Kanno,E. and Fukuda,M.
  TITLE     Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16)
            domain-containing proteins based on their Rab-binding activity
  JOURNAL   Genes Cells 11 (9), 1023-1037 (2006)
   PUBMED   16923123
REFERENCE   4  (bases 1 to 3373)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   5  (bases 1 to 3373)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3373)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   7  (bases 1 to 3373)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   8  (bases 1 to 3373)
  AUTHORS   Hidaka,M., Caruana,G., Stanford,W.L., Sam,M., Correll,P.H. and
            Bernstein,A.
  TITLE     Gene trapping of two novel genes, Hzf and Hhl, expressed in
            hematopoietic cells
  JOURNAL   Mech Dev 90 (1), 3-15 (2000)
   PUBMED   10585558
REFERENCE   9  (bases 1 to 3373)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK035796.1, BC145811.1 and AC154873.6.
            
            On May 7, 2009 this sequence version replaced NM_013862.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035796.1, BC145811.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-155               AK035796.1         2-156
            156-2740            BC145811.1         1-2585
            2741-3373           AC154873.6         251179-251811       c
FEATURES             Location/Qualifiers
     source          1..3373
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 69.64 cM"
     gene            1..3373
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /note="RAB GTPase activating protein 1-like"
                     /db_xref="GeneID:29809"
                     /db_xref="MGI:MGI:1352507"
     exon            1..203
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            204..383
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..2693
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /note="isoform a is encoded by transcript variant 1; rab6
                     GTPase activating protein-like; rab GTPase-activating
                     protein 1-like"
                     /codon_start=1
                     /product="rab GTPase-activating protein 1-like isoform a"
                     /protein_id="NP_038890.3"
                     /db_xref="CCDS:CCDS15408.1"
                     /db_xref="GeneID:29809"
                     /db_xref="MGI:MGI:1352507"
                     /translation="MEVRASFQKVSGSSDSVATLNSEEFVLVSQHTDATSIKDDGKPQ
                     LKIASNGDEQLEKAMEEILRDSEKGQSGLPVDCQGSSEISDCPFGDVPASQTTKPPLQ
                     LILDPSNTEISTPRPSSPSRFPEEDSVLFNKLTYLGCMKVSSPRSEVEALRAMATMRA
                     SSQYPFAVTLYVPNVPEGSVRIIDQSSNVEIASFPIYKVLFCARGHDGTAESNCFAFT
                     ESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTF
                     SVSLEVKEDDGKGNFSPVPKDRDKFYFKIKQGIEKKVVITVQQLSNKELAIERCFGML
                     LSPGRNVKNSDMHLLDMESMGKSYDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMT
                     VAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHSSA
                     GDAIYEVVSLQRESDKEEPITPTSAGGPMSPQEDEAEEESDNELSSGTGDVSKDCPEK
                     ILYSWGELLGRWHNNLGGRPKGLFTLVKSGVPEALRAEVWQLLAGCHDNQEMLDKYRI
                     LITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVFDEDIGYCQGQS
                     FLAAVLLLHMPEEQAFCVLVTIMYGYKLRDLYRNNFEDLHCKFYQLEKLMQEQLPDLY
                     SHFCDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHVALALLKTSK
                     EDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQAMRE
                     NQLQQEDPMDRYKFVYL"
     exon            384..576
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            577..787
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            788..962
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1120
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            1121..1231
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1298
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1401
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1568
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..1710
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            1711..1804
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            1805..1955
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            1956..2069
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            2070..2144
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            2145..2270
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            2271..2414
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            2415..2456
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            2457..2585
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            2586..2678
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     exon            2679..3373
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3346..3351
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /note="hexamer: ATTAAA"
     polyA_site      3365
                     /gene="Rabgap1l"
                     /gene_synonym="5830411O09Rik; 8430421H08Rik;
                     9630005B12Rik; Hh1; HHL; mKIAA0471"
                     /note="major polyA site"
ORIGIN      
        1 agtccgcccc ctccctcgcc tcttcctgcc gtgcggtcct ctcccctccc cagcccgctc
       61 cctccgcccc gttccctccg ccctccctgg gcttcggccg cggcggagtg aacgggacgg
      121 gcccggccgc agagctctgg gcggcgggtg ggactcgggc gtctgacaga gttgttgttc
      181 cggcacggcc gcggagacgt gagttgttcc aggtggatgt gggcagagag gtttgcagaa
      241 ctgaaatgga ggtcagagct tcgttccaga aggttagtgg gtcatctgat tctgtggcca
      301 cactgaacag tgaagaattt gttttggttt ctcagcacac agatgccact tctataaagg
      361 atgatgggaa gccacagctg aagatagctt ccaatggtga tgagcagttg gaaaaagcca
      421 tggaagagat tttgagagat tccgagaaag gacaaagcgg tctacctgtt gattgccaag
      481 gatccagtga gatttcagac tgtccctttg gagatgtgcc ggccagccaa acaactaagc
      541 cgcctctcca gttaattttg gatccatcta atacagaaat ttccacaccc agaccatctt
      601 ctccaagcag atttcctgaa gaagacagtg ttctctttaa caagctgaca tacttaggat
      661 gtatgaaggt ttcttcccca cgcagtgaag tggaggcttt acgggccatg gccaccatga
      721 gagcttccag tcagtacccc tttgctgtta ctctgtatgt gcccaatgtt ccagaaggat
      781 ctgtgagaat catagaccag tcaagcaatg tggagatagc atcttttcca atttataaag
      841 tgcttttctg tgcacgtggg catgatggga cagccgagag caattgcttt gcatttacag
      901 agagttctca tggctcagaa gaatttcaga tacatgtttt ctcctgtgaa attaaagagg
      961 cagtaagcag aattttatat agtttctgca ctgcattcaa acgttcttcc agacaagtgt
     1021 ctgatgttaa agactcagtc atcccgactc ccgacagtga tgtgtttacc ttcagtgttt
     1081 ccttggaggt caaagaagat gatggaaaag gaaactttag tcccgtgcct aaggatagag
     1141 ataaatttta tttcaaaata aagcaaggaa tagagaagaa ggttgtgatt acagttcagc
     1201 aactgtctaa caaagaatta gctattgaga gatgttttgg aatgttatta agcccaggtc
     1261 gaaacgtgaa gaacagtgac atgcatttac tggatatgga gtccatggga aagagctatg
     1321 atgggagagc ttacgtcatc acgggcatgt ggaaccccaa cgcaccaata tttctggctc
     1381 ttaatgaaga aacgcccaaa gataaacggg tgtacatgac cgttgcagtg gacatggtgg
     1441 tcacagaggt ggtggagcca gtccgttttc tcctggagac agtagttcgt gtataccctg
     1501 caaatgagag attttggtat ttcagcagaa agactttcac agagactttc ttcatgaggt
     1561 tgaaacagtc tgagggaaaa ggccacagca gtgctggaga tgcaatatat gaagtggtga
     1621 gtctgcagag agaatctgac aaggaggagc ccatcacccc tactagtgct gggggcccaa
     1681 tgtcaccaca ggaggatgaa gcagaagagg agagtgataa tgaactctcg agtggaacag
     1741 gtgatgtgtc aaaagactgt cctgagaaga ttctctattc ttggggagaa ttgttaggaa
     1801 gatggcacaa taaccttggt ggccgaccaa aaggactatt caccttggta aagagtggtg
     1861 ttcctgaggc actaagggca gaagtatggc aactattagc aggatgccat gacaatcagg
     1921 aaatgctgga taaataccga atccttatca caaaggactc tgcacaggag agtgttatta
     1981 ctcgagatat tcatcgtaca tttcctgcac acgattactt caaagacact ggaggcgatg
     2041 gtcaagaatc cctttacaaa atctgcaagg cctactcggt gttcgatgaa gacattgggt
     2101 actgtcaagg acagtctttt cttgctgctg tactactgtt gcatatgcca gaggagcaag
     2161 cattctgtgt tttggtgact attatgtatg gttataaatt gagagactta tacagaaaca
     2221 attttgaaga tcttcattgc aaattctatc aacttgagaa actaatgcag gaacagctgc
     2281 cagacctgta cagccacttc tgtgatctga acctggaagc tcatatgtat gcatcccagt
     2341 ggttcctcac tctctttact gccaagtttc cactctgcat ggtgttccac atcattgacc
     2401 ttctgctgtg tgagggtttg aatataatct ttcatgtagc tttggctctt ctaaagacct
     2461 caaaggaaga cctccttcag gctgattttg aaggtgcttt gaagtttttc agagttcagc
     2521 ttccaaagag ataccgggca gaggagaatg caagaagatt gatggaacag gcttgcaata
     2581 ttaaagtacc aaccaaaaag ctgaagaaat atgaaaaaga atatcaggcg atgcgggaga
     2641 atcagctgca gcaggaggac ccaatggata gatacaagtt tgtatattta taggtaactc
     2701 cagctgttga atttatactg ggaatcttca tgagaagctg aaagaaaggg aaaaagaaag
     2761 tggctttctg ctttcaaaat tgaggaaaat aaaccagaaa atgccaaaag tactgtttta
     2821 gcagtgcacg ttcacttcca cagagacttt taggtgggac tgttccaaga cactctcgag
     2881 gatattgcaa acttgtccct gactatagca catgttaaaa atacaaattt agaagaaaaa
     2941 ataaaaacca aatggtgtat caagcacagt aatgtgattt ccacaaacaa atcataggta
     3001 atagtgatat ttgcatgcag tttgagaatc aaaattatct cattcatagc ttcattagtt
     3061 caggtctata catttatatt gcgtaaatgg tcatgtcaag cccagattgc catgtggcaa
     3121 tgcgatggga taggaggatc attcatgtcc aggagtttaa aaccaggagc atagtgagac
     3181 cccatctaaa aacacaacat aaaacgacga caaatgtctc atggagccca aagaagctgt
     3241 actacaactg aactgtaact gccttgcacc ctttttctgt taaagcaggc atgtataaac
     3301 acttataaac aataacatta tttgtaaagt ttccactgag ataaaattaa acttttaaaa
     3361 atcggtgttt taa
//
