LOCUS       NM_145522               1858 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus Rab9 effector protein with kelch motifs (Rabepk),
            transcript variant 1, mRNA.
ACCESSION   NM_145522
VERSION     NM_145522.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1858)
  AUTHORS   Luo,S., Mao,C., Lee,B. and Lee,A.S.
  TITLE     GRP78/BiP is required for cell proliferation and protecting the
            inner cell mass from apoptosis during early mouse embryonic
            development
  JOURNAL   Mol Cell Biol 26 (15), 5688-5697 (2006)
   PUBMED   16847323
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL929106.5 and AK035343.1.
            
            On Nov 5, 2011 this sequence version replaced NM_145522.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035343.1, BC019800.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-121               AL929106.5         91272-91392         c
            122-1858            AK035343.1         2-1738
FEATURES             Location/Qualifiers
     source          1..1858
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 22.94 cM"
     gene            1..1858
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /note="Rab9 effector protein with kelch motifs"
                     /db_xref="GeneID:227746"
                     /db_xref="MGI:MGI:2139530"
     exon            1..162
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..1287
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /note="isoform 1 is encoded by transcript variant 1; Rab9
                     effector p40"
                     /codon_start=1
                     /product="rab9 effector protein with kelch motifs isoform
                     1"
                     /protein_id="NP_663497.2"
                     /db_xref="CCDS:CCDS15951.1"
                     /db_xref="GeneID:227746"
                     /db_xref="MGI:MGI:2139530"
                     /translation="MRGLRQGIMKQLPILEPGDKPRKATWYTLTCPGDRPCPRVGHSC
                     SYFPPVGDAESGKIFIVGGANPNQSFSDVHTMDLGTHQWDTATREGLLPRYEHASFLP
                     SCSPHSIWVFGGADQSGNRNCLQVMSPEDRTWSTPEVTGSPPSPRTFHTSSAAIGNQL
                     YVFGGGERGAQPVEDVKLHVFDANTLTWSQPETHGSPPSPRHGHVMVAAGTKLFIHGG
                     LAGDKFFDDLHCIDIGDMSWQKLGPTGAVPVGCAAHAAVAVGHHVYMFGGMTATGALN
                     MMYKYHTEKQHWTVLQFDTSLPAGRLDHSMCVIPWPVMSTSENKDSDSVILTLQDEKG
                     DAAEKAETQSGGPHEESPTTVLLCFVFGGMNTEGEVYDDCLVTVVD"
     exon            163..221
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /inference="alignment:Splign:2.1.0"
     exon            222..379
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /inference="alignment:Splign:2.1.0"
     exon            380..532
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /inference="alignment:Splign:2.1.0"
     exon            533..694
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /inference="alignment:Splign:2.1.0"
     exon            695..844
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /inference="alignment:Splign:2.1.0"
     exon            845..994
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1858
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1286..1291
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /note="hexamer: AATAAA"
     polyA_site      1307
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
                     /note="major polyA site"
     polyA_site      1356
                     /gene="Rabepk"
                     /gene_synonym="8430412M01Rik; 9530020D24Rik; Rab9p40"
ORIGIN      
        1 agagttccgg gaggccctga ctaagtttgg cgcgtagtcc cggagacccg gaggcgtaga
       61 gcggttggcc tggacgcgct tccgggactg gggaagagga cgggctccta agctccgccc
      121 catgggtgga gccacgtcca ggacatgcgg gggctgcggc agggcatcat gaagcagctg
      181 cccatcttgg agcctggaga caagcccagg aaagccacat ggtacacttt gacttgccct
      241 ggagacaggc cctgccctcg agttggccac agctgctcat atttcccccc agttggtgat
      301 gccgagagcg ggaagatctt cattgtcggg ggagcaaatc caaaccaaag tttctcagat
      361 gtacacacca tggacttggg aacacaccag tgggacacgg ccaccaggga gggcctcttg
      421 cctcggtacg agcatgccag cttccttccc tcctgctctc ctcacagcat ctgggtgttt
      481 ggaggtgcag accagtcagg aaatcgaaac tgtctgcaag tcatgagtcc tgaagacagg
      541 acgtggagca caccagaagt gactggctcc cctccatccc caagaacatt ccacacatcg
      601 tccgcagcta tcggaaacca actatacgtc tttgggggag gagagagagg tgcccagcct
      661 gtggaggacg tgaagttgca tgtatttgac gcaaacactc tgacatggtc tcaaccggag
      721 acacatggaa gtcctccgtc tcctcggcat ggccatgtga tggtggcagc gggcacaaaa
      781 ctcttcatcc acggaggatt ggcaggggac aagttctttg atgatctcca ttgcattgat
      841 ataggtgaca tgagctggca gaagcttggt cccaccgggg ctgttccagt cggctgtgct
      901 gcccatgccg ccgttgctgt gggacaccat gtatatatgt ttggaggtat gacagccact
      961 ggagcactga acatgatgta caagtatcac acagaaaagc agcactggac tgtacttcag
     1021 tttgacactt ccctacccgc tggacgactg gaccactcca tgtgtgtcat cccatggcca
     1081 gtgatgtcta cctctgagaa taaagactca gattctgtca ttctaaccct ccaagatgag
     1141 aaaggggacg ctgctgagaa agcagagacc cagagtggag gaccacacga ggagagtcca
     1201 actactgtgt tgctctgctt tgtgttcggt gggatgaaca cagaagggga ggtttatgac
     1261 gactgtctcg taactgtagt ggactaataa agcccacatt tgtattactt gtgacttttt
     1321 acaaaagtga aaactctgcc gagctacact gccaaatact ttttgcacaa tatattctct
     1381 catcccagtg cggtggtgca caccaggcat agtagcacac acctttaatc ccagcacttg
     1441 ggaggcagag gccagcctgg tctacgtggt gagttccagg acagccagag ctacatagtg
     1501 aaaccctgtc ttgaaaaacc agacataaaa agcatatcca tcttgcactt aatcaacatt
     1561 tttaactgga tagcctagtg caaataattc cattataaag ttttaccagc aataaaatct
     1621 gtagataccc aagctaggta ttggagtaga caattacgag ttagacactc tttaatatgt
     1681 attagcgaat cactagaaaa aagtacaggc aggaggctag aaagatagca gttacaagag
     1741 cagtgtggga gatccttatt tggttcataa tcacaatgac tgggtgttca cagaatatgt
     1801 acctccccta aaccttgttc aggtgtgggc atattaccca tctggaaaaa aaaaaagt
//
