LOCUS       NM_019400               5440 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus rabaptin, RAB GTPase binding effector protein 1
            (Rabep1), transcript variant 1, mRNA.
ACCESSION   NM_019400
VERSION     NM_019400.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5440)
  AUTHORS   Oueslati Morales,C.O., Ignacz,A., Bencsik,N., Sziber,Z.,
            Ratkai,A.E., Lieb,W.S., Eisler,S.A., Szucs,A., Schlett,K. and
            Hausser,A.
  TITLE     Protein kinase D promotes activity-dependent AMPA receptor
            endocytosis in hippocampal neurons
  JOURNAL   Traffic 22 (12), 454-470 (2021)
   PUBMED   34564930
REFERENCE   2  (bases 1 to 5440)
  AUTHORS   Rivas,S., Silva,P., Reyes,M., Sepulveda,H., Solano,L., Acuna,J.,
            Guerrero,M., Varas-Godoy,M., Quest,A.F.G., Montecino,M. and
            Torres,V.A.
  TITLE     The RabGEF ALS2 is a hypoxia inducible target associated with the
            acquisition of aggressive traits in tumor cells
  JOURNAL   Sci Rep 10 (1), 22302 (2020)
   PUBMED   33339852
  REMARK    GeneRIF: The RabGEF ALS2 is a hypoxia inducible target associated
            with the acquisition of aggressive traits in tumor cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5440)
  AUTHORS   Timmermans,S. and Libert,C.
  TITLE     Overview of inactivating mutations in the protein-coding genome of
            the mouse reference strain C57BL/6J
  JOURNAL   JCI Insight 3 (13), 121758 (2018)
   PUBMED   29997285
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5440)
  AUTHORS   Shi,Y., Lin,S., Staats,K.A., Li,Y., Chang,W.H., Hung,S.T.,
            Hendricks,E., Linares,G.R., Wang,Y., Son,E.Y., Wen,X., Kisler,K.,
            Wilkinson,B., Menendez,L., Sugawara,T., Woolwine,P., Huang,M.,
            Cowan,M.J., Ge,B., Koutsodendris,N., Sandor,K.P., Komberg,J.,
            Vangoor,V.R., Senthilkumar,K., Hennes,V., Seah,C., Nelson,A.R.,
            Cheng,T.Y., Lee,S.J., August,P.R., Chen,J.A., Wisniewski,N.,
            Hanson-Smith,V., Belgard,T.G., Zhang,A., Coba,M., Grunseich,C.,
            Ward,M.E., van den Berg,L.H., Pasterkamp,R.J., Trotti,D.,
            Zlokovic,B.V. and Ichida,J.K.
  TITLE     Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD
            human induced motor neurons
  JOURNAL   Nat Med 24 (3), 313-325 (2018)
   PUBMED   29400714
  REMARK    GeneRIF: Restoring C9ORF72 levels or augmenting its function with
            constitutively active RAB5 or chemical modulators of RAB5 effectors
            rescued patient neuron survival and ameliorated neurodegenerative
            processes in both gain- and loss-of-function C9ORF72 mouse models
REFERENCE   5  (bases 1 to 5440)
  AUTHORS   Lucitti,J.L., Sealock,R., Buckley,B.K., Zhang,H., Xiao,L.,
            Dudley,A.C. and Faber,J.E.
  TITLE     Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation
            in the Collateral Circulation and Severity of Stroke
  JOURNAL   Stroke 47 (12), 3022-3031 (2016)
   PUBMED   27811335
REFERENCE   6  (bases 1 to 5440)
  AUTHORS   Watters,J.W. and Dietrich,W.F.
  TITLE     Genetic, physical, and transcript map of the Ltxs1 region of mouse
            chromosome 11
  JOURNAL   Genomics 73 (2), 223-231 (2001)
   PUBMED   11318612
  REMARK    Erratum:[Genomics 2002 Mar;79(3):462]
REFERENCE   7  (bases 1 to 5440)
  AUTHORS   Korobko,E.V., Smirnova,E.V., Kiselev,S.L., Georgiev,G.P. and
            Korobko,I.V.
  TITLE     Identification of a new alternative-splicing transcript of
            Rabaptin-5 interacting with protein kinase MAK-V
  JOURNAL   Dokl Biochem 370 (1-6), 1-3 (2000)
   PUBMED   11977240
REFERENCE   8  (bases 1 to 5440)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   9  (bases 1 to 5440)
  AUTHORS   Nishimune,H., Uyeda,A., Nogawa,M., Fujimori,K. and Taguchi,T.
  TITLE     Neurocrescin: a novel neurite-outgrowth factor secreted by muscle
            after denervation
  JOURNAL   Neuroreport 8 (16), 3649-3654 (1997)
   PUBMED   9427343
REFERENCE   10 (bases 1 to 5440)
  AUTHORS   Stewart,G.J., Savioz,A. and Davies,R.W.
  TITLE     Sequence analysis of 497 mouse brain ESTs expressed in the
            substantia nigra
  JOURNAL   Genomics 39 (2), 147-153 (1997)
   PUBMED   9027501
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY133091.1, AK134587.1, BC060166.1 and BC080274.1.
            
            On Mar 27, 2014 this sequence version replaced NM_019400.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.115119.1,
                                           SRR1660815.132168.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 BY133091.1         1-2
            3-768               AK134587.1         2-767
            769-925             AK134587.1         769-925
            926-1309            BC060166.1         905-1288
            1310-1432           BC060166.1         1328-1450
            1433-3621           AK134587.1         1434-3622
            3622-5440           BC080274.1         3594-5412
FEATURES             Location/Qualifiers
     source          1..5440
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 43.21 cM"
     gene            1..5440
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /note="rabaptin, RAB GTPase binding effector protein 1"
                     /db_xref="GeneID:54189"
                     /db_xref="MGI:MGI:1860236"
     exon            1..248
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     CDS             215..2803
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /note="isoform 1 is encoded by transcript variant 1; rab
                     GTPase-binding effector protein 1; rabaptin 5;
                     neurocrescin; RAB5 effector protein"
                     /codon_start=1
                     /product="rab GTPase-binding effector protein 1 isoform 1"
                     /protein_id="NP_062273.2"
                     /db_xref="CCDS:CCDS24968.1"
                     /db_xref="GeneID:54189"
                     /db_xref="MGI:MGI:1860236"
                     /translation="MAQPGPAPQPDVSLQQRVAELEKINAEFLRAQQQLEQEFNQKRA
                     KFKELYLAKEEDLKRQNAVLQAAQDDLGHLRTQLWEAQAEMENIKAIATVSENTKQEA
                     IDEVKRQWREEVASLQAIMKETVRDYEHQFHLRLEQERAQWAQYRESAEREIADLRRR
                     LSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVK
                     ELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQL
                     KHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRVNKRKD
                     NKKTDTEEEVKIPVVCALTQEESSTPLSNEEEHLDSTHGSVHSLDADLMLPSGDPFSK
                     SDNDMFKDGLRRAQSTDSLGTSSSLQSKALGYNYKAKSAGNLDESDFGPLVGADSVSE
                     NFDTVSLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYR
                     LVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQ
                     ANDQLEKTMKEKQELEDFLKQSAEDSSHQISALVLRAQASEVLLEELQQSFSQAKRDV
                     QEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQLAEDFILPDTVEVLRELVL
                     KYRENIVHVRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIAS
                     ISSLKAELERIKVEKGQLESTLREKSQQLESLQEMKVNLEEQLKKETAAKATVEQLMF
                     EEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDI
                     NQLPET"
     exon            249..377
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            378..581
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            582..742
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            743..862
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            863..998
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1177
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1309
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1777
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            1778..1882
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..1999
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2000..2098
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2099..2239
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2240..2429
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2430..2485
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2486..2584
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2585..2701
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     exon            2702..5425
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5203..5208
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /note="hexamer: ATTAAA"
     polyA_site      5222
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /note="major polyA site"
     regulatory      5403..5408
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
                     /note="hexamer: AATAAA"
     polyA_site      5425
                     /gene="Rabep1"
                     /gene_synonym="Rab5ep; rabaptin-5; rabaptin-5alpha"
ORIGIN      
        1 ttatttcccg ctgtcaggat gaggaggcgg aggtcggcgc tccggtccgt ctctgcccga
       61 ggctgtggcg gcgccggcgg ctccagcctt agcggttcct ccctgggcgg cggtggccgc
      121 ggctcggtcg acgcctcctc cgccagctga gcccgcggca tcccgggacg ccgcttcccc
      181 gcccatcccc gttctccgag gccgcccact ggccatggcg cagccgggcc cggctcccca
      241 gcctgacgtt tctcttcagc aacgggtagc agaattggaa aaaattaatg cagaattttt
      301 acgtgcacag cagcagcttg agcaagaatt taatcaaaag agagcaaaat ttaaggagct
      361 ctatttggct aaagaggagg atctgaagag gcaaaatgca gtattgcaag ctgcacagga
      421 cgatttgggt caccttcgga cacagctgtg ggaggctcag gcagagatgg agaacattaa
      481 ggcaattgcc acagtctctg agaatactaa gcaagaagct atagatgaag ttaaaaggca
      541 atggagagaa gaagttgctt cacttcaggc tataatgaaa gagacagtcc gtgactatga
      601 gcatcagttt cacctgaggc tggagcagga gcgagcacag tgggcacagt atcgagaatc
      661 tgcagagcgg gaaatagctg acttaagaag aaggttgtct gaaggtcaag aggaagaaaa
      721 tttagaaaat gaaatgaaaa aggcccaaga ggatgctgaa aagcttcgtt ctgtcgtgat
      781 gcccatggag aaggaaattg cagctctgaa agataaactg acagaagctg aagacaagat
      841 taaagagctg gaggcctcaa aggttaagga gctgaatcat tatctggagg ccgagaagtc
      901 ttgcaggact gacctggaga tgtacgtagc tgttttgaac actcagaaat ctgtgctaca
      961 ggaagatgct gagaaattga ggaaagaact gcatgaagtt tgccatctct tggaacaaga
     1021 acgacaacaa cacaaccagt taaagcatac atggcagaag gccaacgacc agtttctgga
     1081 atctcagcgt ttgctgatga gagacatgca gagaatggag attgtgttaa cttcggaaca
     1141 gctccgacaa gttgaagaac taaagaagaa agaccaggag gaggatgaac aacaaagggt
     1201 caataagaga aaagataaca agaaaacaga taccgaagaa gaagtaaaaa taccagtagt
     1261 gtgtgcttta actcaagaag aatcttcaac cccattatca aatgaagagg agcatttaga
     1321 cagcacccat gggtcagtcc attccttgga tgcagacttg atgttaccat ctggagatcc
     1381 atttagtaaa tcggacaatg acatgtttaa agatggactc aggagagctc agtctacaga
     1441 cagcttggga acctcaagct cattgcaatc caaagcttta ggctataact acaaagcgaa
     1501 atctgctgga aatttggatg agtcggattt tggaccactg gttggagcag attctgtgtc
     1561 tgagaacttt gatactgtgt cccttgggtc actgcagatg ccaagtggat ttatgttaac
     1621 caaagatcaa gaaagagcaa ttaaggcaat gacacctgag caggaggaga cagcatccct
     1681 cctctccagt gtcacccagg gtatggagag tgcatatgta tctcccagtg gttaccgctt
     1741 agtgagtgag acggaatgga atctcctgca gaaagaggta cataatgctg gaaataagct
     1801 tggtagacgt tgtgatatgt gttccaatta tgaaaaacag ttacaaggaa ttcagattca
     1861 ggaagctgaa acaagagacc aggtgaaaaa actgcagtta atgctcaggc aagctaatga
     1921 ccagcttgag aagacgatga aagagaagca ggagctggag gacttcctca agcagagtgc
     1981 ggaggactca agccaccaga tatctgcact tgttttaaga gcccaagcct ctgaggtctt
     2041 acttgaagag ttacaacaga gcttttccca agcaaagagg gacgttcagg agcagatggc
     2101 ggtgctgatg cagtcacgtg aacaggtttc agaagagttg gtgaggttac agaaagacaa
     2161 cgacagcctc caggggaagc acagcttgca tgtgtcatta cagctagcag aagacttcat
     2221 tcttccagac actgtggagg tgctccggga actggtttta aaatatcgtg agaacattgt
     2281 tcatgtgcgc acagcagcag accacatgga agagaagctg aaggcggaaa tacttttcct
     2341 aaaagagcaa attcaagcgg aacagtgttt aaaagaaaac ctggaagaga cactacagct
     2401 ggaaatagaa aactgcaagg aggaaatagc ttccatttct agtctaaaag ctgaattaga
     2461 aagaataaag gttgaaaagg gacagttgga atctacatta agagagaagt cgcaacaact
     2521 tgagagtctc caagaaatga aagttaattt agaggaacag ttaaagaaag aaactgctgc
     2581 taaggctact gttgaacagc tcatgtttga agagaagaac aaagctcaga ggttgcagac
     2641 agaattagat gtcagtgaac aagtacagag agattttgta aaactttctc agactcttca
     2701 ggtgcagttg gagaggatcc ggcaagcaga ctccttggag aggatccggg ctattctgaa
     2761 tgataccaaa ctgacagaca ttaaccagct ccctgagaca tgacaccctg atagcaggat
     2821 tctaacctgc attttgggtt tttaactcat ctttagaata tttattatta tttaactctt
     2881 aacggaagaa gtcacagcaa aggaagactg aagaaatgca aatctggagg gagaaggctg
     2941 ctgtgtgcag ggacagccaa cacctttcaa agggaacact aataagacac tggactcgat
     3001 tccaacaggt gtgggatcag atgaggtgcc agaaaagttg ctgtttcctg cctgctttct
     3061 ccaacatgga ttttggaaca tatttcctga catgaaagca acttcccaat agtgtttgga
     3121 attacgtttt ctgttcatac aaaccgggag agagaagttt cttttttcag ttgtctaagg
     3181 cttcatcagt agcagtgttc agctagcaga gaggtgtagt gtgctatatg agtattttat
     3241 attaaaatat gaagtgtgag agcaggccat tggctgttga ttgtatttcc cttgctcagt
     3301 gcattttgtt tcctttttac cattttatct tctattggaa gaccttaaat gctactgaaa
     3361 cttgcctgag aactatagga ccatggcaag caaaaacaat taaacaaaat tagaatctga
     3421 atatttggct gaggccatat attggaagtt gaatttatgg aaaaaagcac aaacaacctt
     3481 ggaagcactt tgcacaccgt gatgaacttc ctgggcccaa aggtaccagg gcaaataact
     3541 ggcaccatct accctttcca agtgtttagt tactggatca gtggtgagaa taatattaat
     3601 aaaacaagct atctctgaca tctagtacac atgtataaat ctgcttattt tcagcctgcc
     3661 gcagaggcat actatttatt tttttcagtg tcacatttag aatggtgatg gtttacagat
     3721 cttcatattt ttgttttaca gtttagacct aaagtgtaag caactgctta cagtgaagct
     3781 gggaaactta ctggtttaga atctgcttca cgcttttccg agagttgaga ttcctttgga
     3841 acaggctgtt gagcacagac agctttatga agcagtgcag aatcaggagt gagctcatgt
     3901 actggctgca ggctacccga gagcagccag tggccaccta accatgctat ttaacttgtg
     3961 cagtttcaaa gtaaaaaatg ttttcaagta atttttgtga gtggtgttgg cttacagctg
     4021 gtacccaaag gaacattatg ggagtgagtt aactagactt ttctggttta actaccatca
     4081 attcatagcg taaatggact ttgttagtaa tgagtcatta tgaatttgcc ctcaagatgt
     4141 ttgttacttt cttcttttaa taaaacagat aaggcctact taccccataa ataggttact
     4201 tttataatca tgaatttaaa agtaaatatg aattatggaa acgtgctaaa agcttgccaa
     4261 tgcatggaaa aattaattgg cttaaagtcc cttgtatagt gctacttggt ttaaaaggaa
     4321 tataatatcc tcattgaatt aaaaggatta ttaattataa tgggattaaa ttagatttaa
     4381 gactagtccc tggaccccaa gctgatttgt ttggatcacc attggctaca gttgaatgga
     4441 taattcataa tcatactgaa ctgtgtcact cccagtgaac tgttttgctg aaaccaagta
     4501 tcttacagat cttttctcct gaagctgggg attgtgcagt aaaagcatca tgactagggt
     4561 actgtttaga gtctgtaact tgtggcaaat gtaaactgct gggatccact caattgagaa
     4621 acatcctagg ggaagagaaa ctgaaatgct gggttgaatg aaataaagta atgctgcacc
     4681 accaggtaag cagcagttct ttaaagtcaa gtcagttttc tgcatgagag aaggtttggt
     4741 gtaggagctg acgtcaccag gagaggaaag gttggtctag tttcacacac cttcctgtac
     4801 tgcattcagt ctgtgtagac ctgttctctt gcatgtctga cctggcttaa ctctaaactg
     4861 taacatacct tattctgtgg cttttaattg gcagtcactt ggtcatttct aggcatattt
     4921 acctttcaga acttaagtag gcagatatga aaagatgacc taaagccaag gacaaactgt
     4981 atgcaacaga ccacaatgtt ccttttcttt taaggtgcta gaatttgcac ctcctaccca
     5041 ccaaggagac agacatagcc agactcaact ctggaaggta ttggtgcctg tgaggaaatg
     5101 agccagcaga ggacgctgca gctgtagacc ttcagctctg ctctgagcag actgagtatc
     5161 tgtgttgact gtactgaggc atgcccttaa gaaagtgttc aaattaaaag agctgctgct
     5221 gagtagagtg tgtggccttt tcctttgcat cccagggttc tggttccctt cagaggcaca
     5281 gttttggtac tgctacttaa gatgaagatg gacctggcag tgttcagcag gagcctgtgt
     5341 ccagaattaa aacaaaccaa ccaacccata gactttaatt gtaaagcaaa gtcaaatttt
     5401 tgaataaaaa tttattcaaa ctttaaaaaa aaaaaaaaaa
//
