LOCUS       NM_001364848            3690 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus RAB44, member RAS oncogene family (Rab44), mRNA.
ACCESSION   NM_001364848 XM_006524591
VERSION     NM_001364848.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3690)
  AUTHORS   Noguromi,M., Yamaguchi,Y., Sato,K., Oyakawa,S., Okamoto,K.,
            Murata,H., Tsukuba,T. and Kadowaki,T.
  TITLE     Rab44 Deficiency Induces Impaired Immune Responses to Nickel
            Allergy
  JOURNAL   Int J Mol Sci 24 (2), 994 (2023)
   PUBMED   36674510
  REMARK    GeneRIF: Rab44 Deficiency Induces Impaired Immune Responses to
            Nickel Allergy.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3690)
  AUTHORS   Maruta,Y. and Fukuda,M.
  TITLE     Large Rab GTPase Rab44 regulates microtubule-dependent retrograde
            melanosome transport in melanocytes
  JOURNAL   J Biol Chem 298 (11), 102508 (2022)
   PUBMED   36126775
  REMARK    GeneRIF: Large Rab GTPase Rab44 regulates microtubule-dependent
            retrograde melanosome transport in melanocytes.
REFERENCE   3  (bases 1 to 3690)
  AUTHORS   Longe,C., Bratti,M., Kurowska,M., Vibhushan,S., David,P.,
            Desmeure,V., Huang,J.D., Fischer,A., de Saint Basile,G.,
            Sepulveda,F.E., Blank,U. and Menasche,G.
  TITLE     Rab44 regulates murine mast cell-driven anaphylaxis through
            kinesin-1-dependent secretory granule translocation
  JOURNAL   J Allergy Clin Immunol 150 (3), 676-689 (2022)
   PUBMED   35469841
  REMARK    GeneRIF: Rab44 regulates murine mast cell-driven anaphylaxis
            through kinesin-1-dependent secretory granule translocation.
REFERENCE   4  (bases 1 to 3690)
  AUTHORS   Kadowaki,T., Yamaguchi,Y., Ogawa,K., Tokuhisa,M., Okamoto,K. and
            Tsukuba,T.
  TITLE     Rab44 isoforms similarly promote lysosomal exocytosis, but exhibit
            differential localization in mast cells
  JOURNAL   FEBS Open Bio 11 (4), 1165-1185 (2021)
   PUBMED   33641252
  REMARK    GeneRIF: Rab44 isoforms similarly promote lysosomal exocytosis, but
            exhibit differential localization in mast cells.
REFERENCE   5  (bases 1 to 3690)
  AUTHORS   Kadowaki,T., Yamaguchi,Y., Kido,M.A., Abe,T., Ogawa,K.,
            Tokuhisa,M., Gao,W., Okamoto,K., Kiyonari,H. and Tsukuba,T.
  TITLE     The large GTPase Rab44 regulates granule exocytosis in mast cells
            and IgE-mediated anaphylaxis
  JOURNAL   Cell Mol Immunol 17 (12), 1287-1289 (2020)
   PUBMED   32238914
  REMARK    GeneRIF: The large GTPase Rab44 regulates granule exocytosis in
            mast cells and IgE-mediated anaphylaxis.
REFERENCE   6  (bases 1 to 3690)
  AUTHORS   Yamaguchi,Y., Sakai,E., Okamoto,K., Kajiya,H., Okabe,K., Naito,M.,
            Kadowaki,T. and Tsukuba,T.
  TITLE     Rab44, a novel large Rab GTPase, negatively regulates osteoclast
            differentiation by modulating intracellular calcium levels followed
            by NFATc1 activation
  JOURNAL   Cell Mol Life Sci 75 (1), 33-48 (2018)
   PUBMED   28791425
  REMARK    GeneRIF: Data show that Rab GTPase Rab44 affects nuclear factor of
            activated T-cells c1 (NFATc1) signaling in RANKL-stimulated
            macrophages.
REFERENCE   7  (bases 1 to 3690)
  AUTHORS   Harrow,J.L., Steward,C.A., Frankish,A., Gilbert,J.G.,
            Gonzalez,J.M., Loveland,J.E., Mudge,J., Sheppard,D., Thomas,M.,
            Trevanion,S. and Wilming,L.G.
  TITLE     The Vertebrate Genome Annotation browser 10 years on
  JOURNAL   Nucleic Acids Res 42 (Database issue), D771-D779 (2014)
   PUBMED   24316575
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY203725.1 and AC167363.3.
            
            On Jul 17, 2018 this sequence version replaced XM_006524591.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849381,
                              SAMN00849387 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-404               BY203725.1         2-405
            405-558             AC167363.3         151975-152128
            559-705             AC167363.3         153502-153648
            706-796             AC167363.3         154131-154221
            797-892             AC167363.3         154583-154678
            893-1086            AC167363.3         156295-156488
            1087-2522           AC167363.3         157431-158866
            2523-2604           AC167363.3         162805-162886
            2605-2719           AC167363.3         163563-163677
            2720-2821           AC167363.3         164257-164358
            2822-2898           AC167363.3         165664-165740
            2899-3690           AC167363.3         166501-167292
FEATURES             Location/Qualifiers
     source          1..3690
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 15.14 cM"
     gene            1..3690
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /note="RAB44, member RAS oncogene family"
                     /db_xref="GeneID:442827"
                     /db_xref="MGI:MGI:3045302"
     exon            1..55
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            56..274
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            275..383
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            384..558
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            559..705
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            706..796
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            797..892
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1086
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..2522
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2523..2604
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2605..2719
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2720..2821
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2822..2898
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2899..3690
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3141..3146
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3161
                     /gene="Rab44"
                     /gene_synonym="9830134C10Rik"
ORIGIN      
        1 agacagtgac ctcctcacag gtccgggagc accagcaaac ggcagcctct gagaggcctg
       61 aggcacaatg gagaaaggaa agggagtgtc cagaaaaggc cggaagctgg catccagccg
      121 gcggaggcag gcacgagagc cagctgacgg tcaggatgcc cccgtggccg cggaggctga
      181 gtcctggccc tctgatgctg atgcggagct tcagggcttc ttccaggact gtggagccaa
      241 ggaaaggggc tttgttaccc gggaggatct ggcggaggcc aggttcagct tcctgggtgg
      301 cgaggagccg cagatgatat ttgactgggt ggacgtcgag agtaggggcc acctgtcgct
      361 ggaagaattc agctctggac tcaaaaatgt ctttggctcc agccctggta cccacagact
      421 ccgcacaaag cggtcattgc cctctcaacg agaatctgtg acttccaccc tccctgtccc
      481 tgaggaggcc gatgctgagg agaaagaggc cttcctggcc cttatagggc agatggagac
      541 tggccactcc ctttctgagc aagctgagat ctggaagctg tggagagagt tgcggcagga
      601 ggagccccag ttggcaggca acttggaggg cttcctggcc aagatgagca gccgtttgca
      661 ggaggctcag gcagacaggg aggcactggc atggaccctg agaaagcgag actctgacca
      721 tctctacaag gtgagacagc tctacgagga gacagaggag cagatccgca gggagaagca
      781 gcagctgcag gcccagagcg actcccgggg catggccctc agtgctcaca tgcaggaggc
      841 cctggaggcc aaggagcaag aggttcagcg gctagcagag ggccagagag agctggaggc
      901 tcagctcctc cacctcagca gcacacagca agaggccaac cgggagaacc tgcagctcag
      961 ggaggctgag cgggacctag cagggcagct agaagaggtg cggggacagc tgcaggtgac
     1021 aagaggacac ttggatactg ccaggactag gggcaaagtg tcctggcaga tagaggaaga
     1081 gccaagtgtc cccagggcaa ataaagaggc tccagaccct caggctgtcc ccacagagga
     1141 ggccccactg cctgagctgt ttgggaataa tgacaactgg gaccagttcc tcagcagcat
     1201 tgaagcccat tcccacagaa ccctgcggct ttgctggagc ccacccccaa gcccgagtag
     1261 cacctctgcc ccccagactc cccgcattgt tagacagatc tccatttcca agatatctgc
     1321 tctgcagttt tctcaggagc cagcctcaga tccagacccg ggtccaagag gctcccccga
     1381 ggtgcctcct ggtggtgcca aagatggaaa aggggtggag gaccccaagg gacaggatga
     1441 acaggatgtc agctctaagc agcctgtgga ctcccctgac tcagatgcca gacccaaggg
     1501 ctctttcctc tggagcctgc caggagccct gaccgcggag tctgggactg ttgaagcagc
     1561 tttcagagat cagcttgctt ttgaggctga gccccctcct caggggctct cttcctctcc
     1621 tcagtcccca gccgggtcca gaaaacagac ccagactcca gatctgggtg acaagagcct
     1681 ttggtctgga cccgatccag ccaaacagtc cttagaaaga gaggtcatgg cggaggacct
     1741 gaagctgggt ttagggtctc agggagccac agctctccct gagggagcca cagagccttc
     1801 tctgagcctg gagtctgtgg accaagtagg cccagagaga ccagtgcagg atgcaacaca
     1861 tctggctagg caggagagcc atgctaaggg attccaagaa gcccctggcc aagtccttag
     1921 tctggatagc ctgcctaccc acctccccca gagtctagag gagcagctaa ggcccgagga
     1981 aggaaactta ggagaaagag gtcagcagga ccccggatca gaagccagtg agtctcatgg
     2041 cctggaagct aggagcatgg aatcacccca gcaagatgac cccctgccta acacatcaca
     2101 gcctcctgct gagacggaag tccctgctcc tggccagatg tctcctccga ggggctctcc
     2161 catcttgggg gctggggctg ggcttgcagt gggaacccca gagaccacac acactctcct
     2221 taccctggct gagtcagaag cccagcctgg gcccgtgtcc atgcctgttc aggtggagag
     2281 caagtcaggt gcccctcagc ccacagagcc agaggcagaa agcaggccgg aggacccaag
     2341 aacagactta caggaggctg aacggagttc ttcccctggg gacctcactg ctggcaagcc
     2401 tcaagctgac cctgactacc tctaccatgt cgtcttcttg ggggactcca atgtgggcaa
     2461 gacatcattc ctacacctgc tacatcatga cgcttttgct actgggctga cggccactgt
     2521 aggggtggat tttcgtgtca aaaacctgct ggtagacaac aaaaccttcg ccctgcaact
     2581 gtgggacaca gctggacaag agaggtacca cagcctcaca cgacagctgc ttcgcaaggc
     2641 agagggggtg gtgctcatgt atgacgtcac ctcccaagag agcttcaccc acgtgcgtta
     2701 ctggctcgac tgtctgcagg atgcaggtgt agagggggtg gccatggtcc tgctgggaaa
     2761 caagatggac tgtgaggagg agaggcaggt acccactgaa gctggcagaa ggctcgccca
     2821 ggagctgggg gtgtccttcg gtgagtgcag cgcggccctg ggtcacaata tcctggagcc
     2881 gatgatgaac ctggctcggt cacttaagat gcaagaagac cgcctgaaag cctcattggc
     2941 agaagtgaca cacccacaat caaccaagag agctggctgc tgccactgat caccagcacg
     3001 gtccaatccc agactgactc ttccggtggc ttccattcgg cttcttagac acagctggga
     3061 catagaaacc cagcaggggc caatgtcacc tctgctccac tgagcaaaca taccaggggt
     3121 gaacggcagg acaaatctag attaaactcc acacaagcaa agtgtcccca agtctttcat
     3181 tcaccccagg tgaagagatg gtagggtatt ctagtttcat ttctgtgatg gtaaagactg
     3241 atcaagagca gctcagaggc agggaagggc tcttccagct tatgccaggc cgctgccatc
     3301 attgtcaaga caggaactga agcgggaacc atggaggacg gctgcttact ggctcacaca
     3361 ctgcctaatg cttagctttt atagattgtc caggtctacc tgcctaggat tgttactgcc
     3421 cacagtggat tgaatcaatc atcaagcaaa gcagtgccca gcagacaggc ccagcccagg
     3481 cgggctggcg aggacaattc tctatttaag aatttcctgg ttgattctag atggagttag
     3541 gttgataata aaaaactatc caggatgcag gacacacgtg ggggagggtg ctattctcct
     3601 ttttgaatat ttttggggtt ttgtcggtgt ctggggacgt cttgtacaac cagggcatgg
     3661 ggttgtggag aaggaaataa agcttgcagg
//
