LOCUS       NM_144538               2354 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus RAB3A interacting protein (rabin3)-like 1 (Rab3il1),
            transcript variant 1, mRNA.
ACCESSION   NM_144538 NM_178881
VERSION     NM_144538.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2354)
  AUTHORS   Elliott,K.H., Balchand,S.K., Bonatto Paese,C.L., Chang,C.F.,
            Yang,Y., Brown,K.M., Rasicci,D.T., He,H., Thorner,K.,
            Chaturvedi,P., Murray,S.A., Chen,J., Porollo,A., Peterson,K.A. and
            Brugmann,S.A.
  TITLE     Identification of a heterogeneous and dynamic ciliome during
            embryonic development and cell differentiation
  JOURNAL   Development 150 (8) (2023)
   PUBMED   36971348
REFERENCE   2  (bases 1 to 2354)
  AUTHORS   Chen,M., Zhang,Y., Jiang,K., Wang,W., Feng,H., Zhen,R., Moo,C.,
            Zhang,Z., Shi,J. and Chen,C.
  TITLE     Grab regulates transferrin receptor recycling and iron uptake in
            developing erythroblasts
  JOURNAL   Blood 140 (10), 1145-1155 (2022)
   PUBMED   35820059
  REMARK    GeneRIF: Grab regulates transferrin receptor recycling and iron
            uptake in developing erythroblasts.
            Erratum:[Blood. 2023 Oct 5;142(14):1254. doi:
            10.1182/blood.2023022213.. PMID: 37796517]
REFERENCE   3  (bases 1 to 2354)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2354)
  AUTHORS   Lee,H., Min,K., Yi,J.S., Shi,H., Chang,W., Jackson,L. and
            Bennett,A.M.
  TITLE     A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange
            Factor for Rab3A Protein as a Mitogen-activated Protein (MAP)
            Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6
            (IL-6) Secretion and Myogenesis
  JOURNAL   J Biol Chem 292 (9), 3581-3590 (2017)
   PUBMED   28096466
REFERENCE   5  (bases 1 to 2354)
  AUTHORS   Horgan,C.P., Hanscom,S.R. and McCaffrey,M.W.
  TITLE     GRAB is a binding partner for the Rab11a and Rab11b GTPases
  JOURNAL   Biochem Biophys Res Commun 441 (1), 214-219 (2013)
   PUBMED   24140058
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134437.3, AK161298.1 and BB733894.1.
            
            On Feb 9, 2018 this sequence version replaced NM_144538.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223970.20387.1,
                                           SRR7652917.1247550.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-166               AC134437.3         127688-127853
            167-2229            AK161298.1         840-2902
            2230-2354           BB733894.1         276-400
FEATURES             Location/Qualifiers
     source          1..2354
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 6.26 cM"
     gene            1..2354
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /note="RAB3A interacting protein (rabin3)-like 1"
                     /db_xref="GeneID:74760"
                     /db_xref="MGI:MGI:1922010"
     exon            1..166
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..1307
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     guanine nucleotide exchange factor for Rab3A; guanine
                     nucleotide exchange factor for Rab-3A; rabin3-like 1;
                     rab3A-interacting-like protein 1; rab-3A-interacting-like
                     protein 1"
                     /codon_start=1
                     /product="guanine nucleotide exchange factor for Rab-3A
                     isoform 1"
                     /protein_id="NP_653121.1"
                     /db_xref="CCDS:CCDS29569.1"
                     /db_xref="GeneID:74760"
                     /db_xref="MGI:MGI:1922010"
                     /translation="MWSGQPQQDEGLPVGLSAIPVPWKNLGPSKSNRESSGGLVEAST
                     SWEEAQGEEHPAPAPLDVSRLRSSSMEIREKGSEFLKEELYKAQKELKLKDEECERLC
                     KVRAQLEQELEELTASLFEEAHKMVREANMKQATSEKQLKEAWGKIDMLQAEVTALKT
                     LVITSTPASPNRELHPQLLSPTKAGPRKGHSRQKSTSSSLCPVVCPTAGHIPTPDKEG
                     KEVDTTLFAEFQAWRASPTLDKSCPFLERVYREDVGPCLDFTVQELSALVRTAVEDNT
                     LTIEPVASQTLPAVKVPTVECNNTNTCALSGLARTCHHRIRLGDSDSHYYISPSSRAR
                     ITAVCNFFTYIRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA"
     exon            167..422
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     exon            423..518
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     exon            519..596
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     exon            597..815
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     exon            816..944
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1057
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1157
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1224
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..2354
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2202..2207
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /note="hexamer: AATAAA"
     polyA_site      2224
                     /gene="Rab3il1"
                     /gene_synonym="1200014K04Rik; Rab3ail1"
                     /note="major polyA site"
ORIGIN      
        1 gggcagggga agggctccgg tggggcggag ccgcaaaccc agggcggcca gcgggacaga
       61 ctggcggtgg agcgattgac aggcggcagg gcagctctgg ggcccccggc agagttggcg
      121 gcgcgcgagg acgcggctac ggcggagacg ctgggatgtg gagcggccaa ccccaacaag
      181 acgagggcct ccctgtgggc ctctctgcta tcccagtccc ctggaaaaac ctaggcccca
      241 gcaaaagtaa cagggagtcc tcaggaggcc tggtagaagc ctccacttcc tgggaggagg
      301 cccagggtga ggaacacccg gcacctgctc cactggatgt gtcacgcctg cgcagttcct
      361 ccatggagat ccgagagaag ggctccgagt tcctaaagga ggagctatac aaagcccaga
      421 aggagctgaa gctaaaggat gaagagtgtg aacggctttg caaagtacgt gcacagctgg
      481 agcaggagct tgaggagctg acagccagcc tgtttgagga agctcacaag atggttcggg
      541 aagccaacat gaagcaggcg acatcggaaa agcagttgaa ggaggcttgg ggcaagatcg
      601 acatgctaca ggcagaggtg acagccttga agacattggt catcacatcc acaccagcct
      661 ctcccaaccg tgagctccac ccacagctgc tgagccccac caaagctgga ccccgaaagg
      721 gccactcacg tcaaaagagc accagcagct ccctctgccc tgttgtgtgc cccactgcag
      781 ggcatatccc tacccctgac aaagaaggca aggaggtgga tacgacgctg tttgcagagt
      841 tccaagcttg gagagcttca cctaccctgg ataagagctg ccccttccta gaaagggtgt
      901 accgggagga cgtgggccct tgccttgact tcacagtgca ggagctctca gctctggttc
      961 ggactgctgt ggaggacaac acactcacca ttgagcctgt ggcttcacag acactgcccg
     1021 ctgtgaaggt gcccactgtt gagtgtaaca acaccaacac atgtgccctg agtggcctgg
     1081 cacgtacctg ccaccatcga atccgcctgg gggactctga cagccactat tacatctcac
     1141 cgtcctcccg ggccaggatc accgcagtat gcaacttctt cacctatatt cgctacatcc
     1201 agcaaggtct ggttcggcag gatgctgagc cgatgttctg ggagatcatg aggcttcgga
     1261 agggcatgtc actagccaag cttggcttct tcccccagga ggcctagggc atggccccag
     1321 gcctgaagta agctctgagc tagagcaaac agctgccttg ggacagacag acaagaaatc
     1381 ctggagccag ctctgagcca gaagctgaaa ggacagataa acaaccaggc tgtagagaca
     1441 gttctgagcc cgtaccaccc atccgtcctg agacagacaa aaggacagcc tggcctggac
     1501 ttcatcagat gaccctcttg cccactgagc tctgtagcca acaagagaat ctcaagaaag
     1561 caccaaagac caaggtgctc ggagcaagga gctcagccct ggggagagga cccttgagta
     1621 gccagtaccc tcacacaatc ccctgctgct taccaatgct ctcttgctgc cacatcttca
     1681 gaaaggggct gctctagggt ggctggattt ccagccctgg gacaccagca cccccttgtg
     1741 gccatttctc actctgtttc caagtggcct cattagactg ccccagtggt agggcaaatg
     1801 tctccaatct gaacaaggtg gagagataac tgccccgaag tgctctgaag gtgagtccaa
     1861 gatccctcct ccattcttct gcatggaggc ctccctctcc ccttcctctc cacttcaaca
     1921 ccatctccag gaggccctgt tcctgaagtt gccaggaagt ctgggccctt tcttcctaaa
     1981 gtgtgccacc aggggagcct caggacgtaa ccctgggcag ccatccagac ttcaggggcc
     2041 ctggatgtag gacgggatgg agaggctggg ccaagcagga catggaccct gccttatcca
     2101 tcatagccca ctgggaactg ggctcggggg gaatccaacc tggacatatc cttcaccacg
     2161 cccctatttc cttccaatgg aatgtaacgc gatctctatt taataaagga aggctttgtt
     2221 ggtaggggct aggcggcagt ggccttcact cctgtgccct ggggctctgg ccagggcttg
     2281 ggcatctgaa ggaatgaaat caaatccttt cctaactggc ctcgtgcttg ggattaaacc
     2341 caaatcctga agct
//
