LOCUS       NM_009001               1344 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus RAB3A, member RAS oncogene family (Rab3a), transcript
            variant 2, mRNA.
ACCESSION   NM_009001
VERSION     NM_009001.7
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1344)
  AUTHORS   Izumida,M., Kakoki,K., Hayashi,H., Matsuyama,T. and Kubo,Y.
  TITLE     Rab3a, a small GTP-binding protein, is required for the
            stabilization of the murine leukaemia virus Gag protein
  JOURNAL   Small GTPases 13 (1), 162-182 (2022)
   PUBMED   34180342
  REMARK    GeneRIF: Rab3a, a small GTP-binding protein, is required for the
            stabilization of the murine leukaemia virus Gag protein.
REFERENCE   2  (bases 1 to 1344)
  AUTHORS   Luo,K., Wang,L., Shen,Y., She,S., Cui,Y. and Liu,K.
  TITLE     TET3-mediated accumulation of DNA hydroxymethylation contributes to
            the activity-dependent gene expression of Rab3a in post-mitotic
            neurons
  JOURNAL   J Integr Neurosci 20 (3), 529-539 (2021)
   PUBMED   34645086
  REMARK    GeneRIF: TET3-mediated accumulation of DNA hydroxymethylation
            contributes to the activity-dependent gene expression of Rab3a in
            post-mitotic neurons.
REFERENCE   3  (bases 1 to 1344)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1344)
  AUTHORS   Avagliano Trezza,R., Punt,A.M., Mientjes,E., van den Berg,M.,
            Zampeta,F.I., de Graaf,I.J., van der Weegen,Y., Demmers,J.A.A.,
            Elgersma,Y. and Distel,B.
  TITLE     Mono-ubiquitination of Rabphilin 3A by UBE3A serves a
            non-degradative function
  JOURNAL   Sci Rep 11 (1), 3007 (2021)
   PUBMED   33542309
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1344)
  AUTHORS   Hanes,A.L., Koesters,A.G., Fong,M.F., Altimimi,H.F., Stellwagen,D.,
            Wenner,P. and Engisch,K.L.
  TITLE     Divergent Synaptic Scaling of Miniature EPSCs following Activity
            Blockade in Dissociated Neuronal Cultures
  JOURNAL   J Neurosci 40 (21), 4090-4102 (2020)
   PUBMED   32312887
REFERENCE   6  (bases 1 to 1344)
  AUTHORS   Geppert,M., Goda,Y., Stevens,C.F. and Sudhof,T.C.
  TITLE     The small GTP-binding protein Rab3A regulates a late step in
            synaptic vesicle fusion
  JOURNAL   Nature 387 (6635), 810-814 (1997)
   PUBMED   9194562
REFERENCE   7  (bases 1 to 1344)
  AUTHORS   Dechesne,C.J., Kauff,C., Stettler,O. and Tavitian,B.
  TITLE     Rab3A immunolocalization in the mammalian vestibular end-organs
            during development and comparison with synaptophysin expression
  JOURNAL   Brain Res Dev Brain Res 99 (1), 103-111 (1997)
   PUBMED   9088571
REFERENCE   8  (bases 1 to 1344)
  AUTHORS   Inagaki,N., Mizuta,M. and Seino,S.
  TITLE     Cloning of a mouse Rabphilin-3A expressed in hormone-secreting
            cells
  JOURNAL   J Biochem 116 (2), 239-242 (1994)
   PUBMED   7822236
REFERENCE   9  (bases 1 to 1344)
  AUTHORS   Geppert,M., Bolshakov,V.Y., Siegelbaum,S.A., Takei,K., De
            Camilli,P., Hammer,R.E. and Sudhof,T.C.
  TITLE     The role of Rab3A in neurotransmitter release
  JOURNAL   Nature 369 (6480), 493-497 (1994)
   PUBMED   7911226
REFERENCE   10 (bases 1 to 1344)
  AUTHORS   Baumert,M., Fischer von Mollard,G., Jahn,R. and Sudhof,T.C.
  TITLE     Structure of the murine rab3A gene: correlation of genomic
            organization with antibody epitopes
  JOURNAL   Biochem J 293 (Pt 1) (Pt 1), 157-163 (1993)
   PUBMED   7687127
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CAAA01070179.1.
            
            On Mar 12, 2020 this sequence version replaced NM_009001.6.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK161975.1, CX240994.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-161               CAAA01070179.1     13988-14148         c
            162-389             CAAA01070179.1     12770-12997         c
            390-508             CAAA01070179.1     12288-12406         c
            509-633             CAAA01070179.1     11592-11716         c
            634-1344            CAAA01070179.1     10246-10956         c
FEATURES             Location/Qualifiers
     source          1..1344
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.15 cM"
     gene            1..1344
                     /gene="Rab3a"
                     /note="RAB3A, member RAS oncogene family"
                     /db_xref="GeneID:19339"
                     /db_xref="MGI:MGI:97843"
     exon            1..161
                     /gene="Rab3a"
                     /inference="alignment:Splign:2.1.0"
     exon            162..389
                     /gene="Rab3a"
                     /inference="alignment:Splign:2.1.0"
     exon            390..508
                     /gene="Rab3a"
                     /inference="alignment:Splign:2.1.0"
     exon            509..633
                     /gene="Rab3a"
                     /inference="alignment:Splign:2.1.0"
     exon            634..1344
                     /gene="Rab3a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1321..1326
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab3a"
                     /note="hexamer: AATAAA"
     polyA_site      1344
                     /gene="Rab3a"
                     /note="major polyA site"
ORIGIN      
        1 ggctttgcag gacgtcagct aggactgcag gggcctgagc ctcctccgct gccgcctgca
       61 gcccccgccg ccgcctgcat cccccgcatc ctcttctggg gcccggtcgc cagcgcagtc
      121 gccacggtcg ccgtcgccag cgttgtctca gcttagagag gatggcttcc gccacagact
      181 ctcgctatgg gcagaaggag tcctcagacc agaacttcga ctatatgttc aagatcctga
      241 tcattgggaa cagcagcgtg ggcaaaacct cgttcctctt ccgctacgca gatgactcct
      301 tcactccagc ctttgtcagc accgttggca tagacttcaa ggtcaaaacc atctaccgca
      361 acgacaagag gatcaagctg cagatctggg acacagcagg gcaagagcgg taccgcacca
      421 tcaccacagc ctattaccga ggcgccatgg gcttcatcct aatgtatgac atcaccaatg
      481 aggagtcatt taatgcagtg caggactggt ccactcagat caaaacttac tcgtgggaca
      541 atgcccaggt gctgctggtg ggaaacaagt gtgacatgga agatgagcga gtggtgtcct
      601 cagagcgtgg ccggcagctg gctgaccacc tgggctttga gttctttgag gccagcgcca
      661 aggacaacat taatgtcaag cagacgtttg aacgtctggt ggacgtgatc tgtgagaaga
      721 tgtcagagtc cctggatact gcagaccctg cggtcaccgg tgccaagcag ggcccgcagc
      781 tcaccgacca gcaggcgcca cctcatcagg attgtgcctg ctgagccact tcccttccct
      841 gctgccaggg gcacgtcccc catccccgac taccctattt attattgtag ctatttattt
      901 atttattgag gatgtgcccc gagcgcaccc ccttcccacc ctgtacatag ctccacccag
      961 ctcggccgtg gtgtattgtg gtcactgctg ctccctctcc tttacccccc acccccattt
     1021 tgtttttgta aaccatcccg tccacagttg tcagttgtga agaggggacc agatgtcact
     1081 ctgcagcagg ctgatggaag atggcggggc ctgccaaccc cgaggctggg ggatcgccat
     1141 atggaccacc tggttgacag acggcttctt gcttgcctgg gccttctgcc ttatactttg
     1201 ggataaatgg ggtgtagggg atatattcac tactttggga tacccccaaa cctgttctga
     1261 cgtcgtgagt gtcaaatgtg tcccactcct ccctagaagt tatgaacact acacacagtc
     1321 aataaagcga atggaccttg ctga
//
