LOCUS       NM_001359272            4266 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus RAB36, member RAS oncogene family (Rab36), transcript
            variant 3, mRNA.
ACCESSION   NM_001359272 XM_011243599
VERSION     NM_001359272.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4266)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4266)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4266)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 4266)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 4266)
  AUTHORS   Matsui,T., Ohbayashi,N. and Fukuda,M.
  TITLE     The Rab interacting lysosomal protein (RILP) homology domain
            functions as a novel effector domain for small GTPase Rab36: Rab36
            regulates retrograde melanosome transport in melanocytes
  JOURNAL   J Biol Chem 287 (34), 28619-28631 (2012)
   PUBMED   22740695
  REMARK    GeneRIF: Rab36 mediates retrograde melanosome transport in
            melanocytes through interaction with RILP.
REFERENCE   6  (bases 1 to 4266)
  AUTHORS   Itoh,T., Satoh,M., Kanno,E. and Fukuda,M.
  TITLE     Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16)
            domain-containing proteins based on their Rab-binding activity
  JOURNAL   Genes Cells 11 (9), 1023-1037 (2006)
   PUBMED   16923123
REFERENCE   7  (bases 1 to 4266)
  AUTHORS   Fukuda,M.
  TITLE     Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and
            Noc2. Identification of a critical determinant of Rab3A/Rab27A
            recognition by Rim2
  JOURNAL   J Biol Chem 278 (17), 15373-15380 (2003)
   PUBMED   12578829
REFERENCE   8  (bases 1 to 4266)
  AUTHORS   Fukuda,M., Kuroda,T.S. and Mikoshiba,K.
  TITLE     Slac2-a/melanophilin, the missing link between Rab27 and myosin Va:
            implications of a tripartite protein complex for melanosome
            transport
  JOURNAL   J Biol Chem 277 (14), 12432-12436 (2002)
   PUBMED   11856727
REFERENCE   9  (bases 1 to 4266)
  AUTHORS   Kuroda,T.S., Fukuda,M., Ariga,H. and Mikoshiba,K.
  TITLE     The Slp homology domain of synaptotagmin-like proteins 1-4 and
            Slac2 functions as a novel Rab27A binding domain
  JOURNAL   J Biol Chem 277 (11), 9212-9218 (2002)
   PUBMED   11773082
REFERENCE   10 (bases 1 to 4266)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK142415.1, AC142500.23, AK038445.1, CJ315423.1 and BQ173929.1.
            
            On Dec 30, 2017 this sequence version replaced XM_011243599.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK142025.1, AB232632.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-309               AK142415.1         2-310
            310-310             AC142500.23        192032-192032
            311-1453            AK142415.1         312-1454
            1454-3601           AK038445.1         474-2621
            3602-3617           CJ315423.1         369-384
            3618-4266           BQ173929.1         1-649               c
FEATURES             Location/Qualifiers
     source          1..4266
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 38.49 cM"
     gene            1..4266
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /note="RAB36, member RAS oncogene family"
                     /db_xref="GeneID:76877"
                     /db_xref="MGI:MGI:1924127"
     exon            1..1295
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1387
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1453
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1555
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1620
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1672
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1673..1754
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1755..1845
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1846..1971
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..4249
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4226..4231
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      4249
                     /gene="Rab36"
                     /gene_synonym="6330593L16Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtcgggattc gggagctacg agccagtccc gcgaggccac tgttgctgtg gtgatttgca
       61 gcggcctgcg cgccggaacc tggtctttgc agcttggtga gtcctctcac cctcccggct
      121 gcagacgcgt cctggaggtt atggtcctga ggctgtcaag ccccctgccc tccacctacc
      181 cccaagcctg agtgtggcct gcaggcctgg tcttcctcag tgagcgtcca tcctgggcca
      241 ggcctctgca ggagccaggt cagaagagga cagcagattt aggagtggtg gtggggtaga
      301 ttctgggtga tgtagggcag ggaaagtggc tagaacctaa attcactcag agactccaac
      361 agactaaggg caagggaccc ctccctactc tattccatag ccaggattgg gttttgtatg
      421 tttggtttgg tttttggatt gtttgttttt ttaatacctc ccacatgcca aggaagtgaa
      481 tgcaaagaag gagcccctct tcctaggcat ggggtcacct cccgactcgg caagatgggg
      541 tatgggctgc ccttcctcca ctgtgctgcc tacagcgtga atggcctctg cctaacaatg
      601 gtggtaggga tggagaccca gatatgtttt aagtcacagg tgcattttga gaacttgtat
      661 ggcttcctgg gtcttgttaa aagacaaata taacaatttt tgccctaatt gactctgtga
      721 atgtagaatt gggcaacact tcatcctgtg aaataaactt gagtgttgtc ttgttttgct
      781 tggctccgtt tgagtctctt ggtgtgacag gctctcagtg tgtcatggaa ggactccgga
      841 acccatcacc ctcctgcctc tgcttcccaa gtgctgactg tatagacccg tatcacgact
      901 gcacgtgggt aggagtttga ttttatagac agaaaaagga aggagagtaa aaatagtaaa
      961 aagcaaattg gttatttcaa agttacttca attggaggat aattcatgcc agctcaggtt
     1021 gactggtccc cttgacttcc cacagaagtc ccaaagatct cttgttttgt tggaaaacta
     1081 gcccattcag aattctgttt gatcatgtga cacctagcat aatctgttct agtccgaccg
     1141 actgggccat aatgcagaaa ctacgtcttg catgttttat gtaatactct ttaccccact
     1201 gattgagtct gcagaacact ggaagaatga ggtcctcttg gacccctttg gggccccctg
     1261 tgagccagga ccgcatcatc accagcttcc ctaagtggta cacgccggat gcctgcctgc
     1321 agctcaaaga gcacttccac agccgcgtca gcacagcctg ccagcacagg aacacaggca
     1381 ctgctgggct cagactctcc aaggtggtgg tcgttggcga tctctacgtg ggaaagacta
     1441 gcctcattca caggttgtgc aagaatgttt tcgaccatga ttacaaggcc acgatcggcg
     1501 tggactttga aatcgagcgc tttgagatcg cagggattcc ctacagcctc cagatctggg
     1561 acacagccgg gcaggagaag ttcaagtgta ttgcgtctgc ctactaccgc ggtgcccagg
     1621 tgatcatcac agcctttgac ctcactgacg tgcagactct ggaacatacc aggcagtggc
     1681 tggaggacgt gctgagggag aatgaggcag gctcctgctt catcttcctc gtgggaacca
     1741 agaaggatct cctgtcgggg gcagcgtgcg agcaagcgga agctgaggct gtgcatctgg
     1801 ccaatgagat gcaggcagag tactggtctg tgtcagctaa gacgggagag aatgtgaagg
     1861 cattcttcag ccgcgtcgcc gccctagcct ttgaacagtc tgtacttcag gacctagaga
     1921 agaggcccag cacccagtcc caggtcggag atggagatgg agacctaata cgaatagagg
     1981 tacccaaaac ccaggagaac aagaggccgc ccggcctagg ctgctgttaa ccgtggccag
     2041 aatcagagcc atctacagga tgactggagc ccaggctcta cagcggatat gccttcaagc
     2101 tggagaagcc tcgtgtcttc agagcccagc cattttgctt tagccggtca gcagccactg
     2161 gctgctgaag ccccatactg cccggttggt tgatgggtgc cagcatgagc cttccctata
     2221 gggtcttcag atggttgttg tgttcttaag aggcctcaag actgcaaact cgggacacct
     2281 cagggctagc ccacacccct tacccaatca taccaacagc tgtggagccc tttcctggcg
     2341 gagcctctgg ggtctctgaa ccctcatctc catgttccaa gcaccgagac ttgtcagagg
     2401 aagcgagtaa aactaaaatg ctctcccacc tggagttctc tgtcatcacg aaggcatgga
     2461 gttctaggcc tttcagcttc aaacctggct ctcccaggac tctggagctc catccactgc
     2521 taagcacaat ggacaaagtc cgtttggccc ctctggcaga gtcccgcccc catctctgag
     2581 attcccgtgg ttctgctatt agtgggtcag aaggtggacc tctggctcat cactgtgacc
     2641 atccgaggga tggagattgc atggtgacct ttggagcctc acgagaggaa tcactgtgac
     2701 catgctgaga gatgacaatg cctggtgtcc ctttggcaac tcattccgca tccctgagcc
     2761 tgatactgtc ctgtgtttta cctatggcca tccctgctgg cctaccgtgt gtctgtccag
     2821 ctggcctgtg tgtctctcgg gaccttggca ttgggccacc tatctctgga ggacttggga
     2881 cacgcagaat ctagcatgcc tagctccttt ctgcacatcc gcaggagcac tgcgccctat
     2941 gtggcccagg gtcttcccaa tcccctctcc tactctgtat tcctgtagct ctgggtccag
     3001 acccacatac ccatctttct cctgccataa gagggtggga acacccagca ttcctatctg
     3061 ctgtcccctc ccccaagaca gggtctcatg tagtccatgc tggcttccaa ctccatatgt
     3121 agctgaggct taccttggat tttatttacc gtccatctcc caaatgctag aattagagag
     3181 atgtaccacc atacctagca acacctgctt accgaggatg gtgagcatct gcaggcagcc
     3241 atgttggtcc atgccttttt tctaagtgcc tggcatacca cacctttcta tgactgttca
     3301 ttaactcagc agtggccaaa catcagagag cgctgaccta tctccctgtt cgatacagca
     3361 ttctttagcc ttgttttagt gagccctctc tccctctcca ctgcccaccc cactctgaaa
     3421 cattgtgtca ctatgtatac taagctggcc ttgagattgc agcagccccc tgcctctgcc
     3481 tcccaagagc tggggttata gacgtgaagc tcatatttgg cttaaggtct tttattctaa
     3541 aaagtatata aaacatctct ttaaaggatt caatgtttgg tattaaacaa ggtggtagag
     3601 cattaaaaaa aaaaaatgaa aatacttctg ccctgaagtt agttgtactc tcggagttga
     3661 acatggttaa cagttgataa aaattccttc tgtgctctcc ttccccagcc cgccctgtgt
     3721 gcaaaccccc atgctggctt gtttctccga gtgtccttgt actgtgcaca ctgcctgatg
     3781 ggccacctgc ccagtcatct gccctgatct ctccctgtga gtgcatgcca ggccttccca
     3841 tacttagcaa aacatgtggt ttccttagtg ccgatagact gtggcccact tgcgttcctt
     3901 atctactggc tggccagccg gcaggtttgt gtctgctgtt gttagctttc ccctgtggca
     3961 ctttaggatt tccacagaag gtctttgtgg gctctcctct ggactgtggt cccttccctg
     4021 atccatgaag acagggcctg ttagggacag gctacattgt tgttgcagcc cagaaggtta
     4081 gggcttagtg gtcgcctgat gcctgtcttc ctcctaggtc ctgggatggt gatgggaaag
     4141 ggatgataat gtgtcctcct gtcatgagct ccagagccag aagtaactgt ttttcacacc
     4201 cccacatccc tggagatcac ccattattaa actctcctca tgttttccaa aaaaaaaaaa
     4261 aaaaaa
//
