LOCUS       NM_198163               2181 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus RAB35, member RAS oncogene family (Rab35), mRNA.
ACCESSION   NM_198163
VERSION     NM_198163.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2181)
  AUTHORS   Clearman,K.R., Timpratoom,N., Patel,D., Rains,A.B., Haycraft,C.J.,
            Croyle,M.J., Reiter,J.F. and Yoder,B.K.
  TITLE     Rab35 Is Required for Embryonic Development and Kidney and Ureter
            Homeostasis through Regulation of Epithelial Cell Junctions
  JOURNAL   J Am Soc Nephrol 35 (6), 719-732 (2024)
   PUBMED   38530365
REFERENCE   2  (bases 1 to 2181)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2181)
  AUTHORS   Maejima,I., Hara,T., Tsukamoto,S., Koizumi,H., Kawauchi,T.,
            Akuzawa,T., Hirai,R., Kobayashi,H., Isobe,I., Emoto,K., Kosako,H.
            and Sato,K.
  TITLE     RAB35 is required for murine hippocampal development and functions
            by regulating neuronal cell distribution
  JOURNAL   Commun Biol 6 (1), 440 (2023)
   PUBMED   37085665
  REMARK    GeneRIF: RAB35 is required for murine hippocampal development and
            functions by regulating neuronal cell distribution.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2181)
  AUTHORS   Lu,C., Wang,D., Feng,Y., Feng,L. and Li,Z.
  TITLE     miR-720 Regulates Insulin Secretion by Targeting Rab35
  JOURNAL   Biomed Res Int 2021, 6662612 (2021)
   PUBMED   33880375
  REMARK    GeneRIF: miR-720 Regulates Insulin Secretion by Targeting Rab35.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2181)
  AUTHORS   Bhat,S., Ljubojevic,N., Zhu,S., Fukuda,M., Echard,A. and Zurzolo,C.
  TITLE     Rab35 and its effectors promote formation of tunneling nanotubes in
            neuronal cells
  JOURNAL   Sci Rep 10 (1), 16803 (2020)
   PUBMED   33033331
  REMARK    GeneRIF: Rab35 and its effectors promote formation of tunneling
            nanotubes in neuronal cells.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2181)
  AUTHORS   Gurkan,C., Lapp,H., Alory,C., Su,A.I., Hogenesch,J.B. and
            Balch,W.E.
  TITLE     Large-scale profiling of Rab GTPase trafficking networks: the
            membrome
  JOURNAL   Mol Biol Cell 16 (8), 3847-3864 (2005)
   PUBMED   15944222
REFERENCE   7  (bases 1 to 2181)
  AUTHORS   Fukuda,M.
  TITLE     Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and
            Noc2. Identification of a critical determinant of Rab3A/Rab27A
            recognition by Rim2
  JOURNAL   J Biol Chem 278 (17), 15373-15380 (2003)
   PUBMED   12578829
REFERENCE   8  (bases 1 to 2181)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 2181)
  AUTHORS   Fukuda,M., Kuroda,T.S. and Mikoshiba,K.
  TITLE     Slac2-a/melanophilin, the missing link between Rab27 and myosin Va:
            implications of a tripartite protein complex for melanosome
            transport
  JOURNAL   J Biol Chem 277 (14), 12432-12436 (2002)
   PUBMED   11856727
REFERENCE   10 (bases 1 to 2181)
  AUTHORS   Kuroda,T.S., Fukuda,M., Ariga,H. and Mikoshiba,K.
  TITLE     The Slp homology domain of synaptotagmin-like proteins 1-4 and
            Slac2 functions as a novel Rab27A binding domain
  JOURNAL   J Biol Chem 277 (11), 9212-9218 (2002)
   PUBMED   11773082
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC056466.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC056466.1, AK156576.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2181
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 56.1 cM"
     gene            1..2181
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /note="RAB35, member RAS oncogene family"
                     /db_xref="GeneID:77407"
                     /db_xref="MGI:MGI:1924657"
     exon            1..212
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /inference="alignment:Splign:2.1.0"
     CDS             161..766
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /codon_start=1
                     /product="ras-related protein Rab-35"
                     /protein_id="NP_937806.1"
                     /db_xref="CCDS:CCDS19596.1"
                     /db_xref="GeneID:77407"
                     /db_xref="MGI:MGI:1924657"
                     /translation="MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVD
                     FKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRW
                     LHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEM
                     FNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC"
     exon            213..263
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /inference="alignment:Splign:2.1.0"
     exon            264..387
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /inference="alignment:Splign:2.1.0"
     exon            388..512
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /inference="alignment:Splign:2.1.0"
     exon            513..637
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /inference="alignment:Splign:2.1.0"
     exon            638..2163
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2140..2145
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /note="hexamer: AATAAA"
     polyA_site      2163
                     /gene="Rab35"
                     /gene_synonym="9530019H02Rik; H-ray; RAB1C; RAY"
                     /note="major polyA site"
ORIGIN      
        1 tgtttctgtc agttccggct gtttgttcgg gaagtggatc cgccgctgcc ggagcagccg
       61 ggagggagct gcggatcgcg aggccaggac cgaccccgcc cgcccagctc gcctgcccgc
      121 ccgcgcgcgc gcgcccgccc gcccgccgcc cccgcccgcc atggcccggg actacgacca
      181 cctcttcaag ctgctcatca tcggcgacag cggtgtgggc aagagcagct tgctgttacg
      241 attcgcagac aacaccttct caggcagcta catcaccaca atcggagtgg atttcaagat
      301 tcggactgtg gagatcaacg gggagaaggt gaagctgcag atctgggaca cggcagggca
      361 ggagcgcttc cgcaccatca cctctacgta ttatcggggg acccatgggg tcattgtggt
      421 ttacgacgtc actagtgccg agtcctttgt caacgtcaag cgatggcttc atgaaatcaa
      481 ccagaactgt gacgatgtgt gccgaatatt agtgggcaat aagaatgatg accctgagcg
      541 gaaggtggta gagacagaag atgcctacaa atttgccggg cagatgggga tccagctctt
      601 tgagaccagt gccaaggaga acgtcaatgt ggaagagatg ttcaactgta tcacagagct
      661 ggttctgcga gcaaagaaag acaacttggc gaaacagcag cagcaacaac agaacgatgt
      721 ggtgaagctc accaaaaaca gtaaacgaaa gaaacgctgc tgctaatgcc ccagccccag
      781 cagagactgc actgcatccc tcccagcctg aggcctggag gcctcggggg acagtctcag
      841 tttagtgccg ttatttaaag aattctcgcc acgttttttg tatggggagg cgccatcggc
      901 acttcctccc cttttcccct tgagtgccaa gaaggtgttg gacgagcccg cccttcccca
      961 cggtgccctc ttccctgccg aggcgcatgg acctggtgag gacgctgcca gctgagtgga
     1021 ctgattaacc agtttgtaca tagtgtatat tgcattaacc agctgcacac cctcagcctg
     1081 ctctggcttt tggctccttc ctgccaacct gctgcaacag accctcccca gccctccgtc
     1141 ccagctcgac ggcagcttcc ggaggagcca acctcgtgtc ctagccgagt ctttggccat
     1201 tcatccctgg cccatggagt gcactccaca tggctcctac cctacagctg ctctgggagc
     1261 tgggaacctg gctccacaca ggccctgccc tctgctggcc gctaggcctt cagttccttc
     1321 cacagaggaa ctcagtcctg cccttttgga caacaggttt ctcattctgc cttctagatg
     1381 cctctgctac agacccagga gagccatggc ttctcactta cccaacatgt ttcagttccc
     1441 gcagaaaggt agtgggacat ctgtaaagag acggagctcg caaggaggag cattttaaca
     1501 aatacagcca atgaagccaa atcaaatgaa ctaagttcct cacgattatt tccttgagat
     1561 ctgattggct caatagcaaa agatatgact gtcccacatc gggctcagta tttttagaaa
     1621 aggtgtatgg cttctgttga gtgcagggct aggcgctctc ccttccatgg gaaaggctgg
     1681 ctttgcaccc tcatacctgt gtgctcgagg gcctcccact ggagaaagaa agtctgtaat
     1741 gtagcaccag gcgcctgtgc cagagccagg ggttgctggg ctctgggaag gcacctcaag
     1801 ctgggaccga ctggtggttt ttgcattact gacagatgtg tttttagtat gaaggtggta
     1861 ggaagatttt ctagccactg ggaagaagcg gcagtggggt gggggcagcc agtattcacc
     1921 tagccaccca ctagggtgat ctgcatttgg ttactcctcc cttccccaca cttggtcccc
     1981 cttcccctga aggatcacgt aactcagaag aactgatttg gacacataat gtgttttaga
     2041 ttttctttcc taggcgattt ccaggcacag tcctgactgg acaatcatca cagaatactg
     2101 cagattttcc atgttaacac tgtggatggg ttttcaatca ataaaactgg ggctttcttc
     2161 tcaaaaaaaa aaaaaaaaaa a
//
