LOCUS       NM_011228               1183 bp    mRNA    linear   ROD 23-DEC-2022
DEFINITION  Mus musculus RAB33A, member RAS oncogene family (Rab33a), mRNA.
ACCESSION   NM_011228
VERSION     NM_011228.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1183)
  AUTHORS   Gendrel AV, Tang YA, Suzuki M, Godwin J, Nesterova TB, Greally JM,
            Heard E and Brockdorff N.
  TITLE     Epigenetic functions of smchd1 repress gene clusters on the
            inactive X chromosome and on autosomes
  JOURNAL   Mol Cell Biol 33 (16), 3150-3165 (2013)
   PUBMED   23754746
REFERENCE   2  (bases 1 to 1183)
  AUTHORS   Nakazawa H, Sada T, Toriyama M, Tago K, Sugiura T, Fukuda M and
            Inagaki N.
  TITLE     Rab33a mediates anterograde vesicular transport for membrane
            exocytosis and axon outgrowth
  JOURNAL   J Neurosci 32 (37), 12712-12725 (2012)
   PUBMED   22972995
  REMARK    GeneRIF: Studies examining overexpression and inhibition of rat
            Rab33a suggest that this protein is involved in the transport of
            post-Golgi synaptophysin-positive vesicles and axon growth in the
            rat brain.
REFERENCE   3  (bases 1 to 1183)
  AUTHORS   Cheng E, Trombetta SE, Kovacs D, Beech RD, Ariyan S, Reyes-Mugica
            M, McNiff JM, Narayan D, Kluger HM, Picardo M and Halaban R.
  TITLE     Rab33A: characterization, expression, and suppression by epigenetic
            modification
  JOURNAL   J Invest Dermatol 126 (10), 2257-2271 (2006)
   PUBMED   16810302
REFERENCE   4  (bases 1 to 1183)
  AUTHORS   Itoh T, Satoh M, Kanno E and Fukuda M.
  TITLE     Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16)
            domain-containing proteins based on their Rab-binding activity
  JOURNAL   Genes Cells 11 (9), 1023-1037 (2006)
   PUBMED   16923123
REFERENCE   5  (bases 1 to 1183)
  AUTHORS   Fukuda M.
  TITLE     Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and
            Noc2. Identification of a critical determinant of Rab3A/Rab27A
            recognition by Rim2
  JOURNAL   J Biol Chem 278 (17), 15373-15380 (2003)
   PUBMED   12578829
REFERENCE   6  (bases 1 to 1183)
  AUTHORS   Zheng JY, Koda T, Fujiwara T, Kishi M, Ikehara Y and Kakinuma M.
  TITLE     A novel Rab GTPase, Rab33B, is ubiquitously expressed and localized
            to the medial Golgi cisternae
  JOURNAL   J Cell Sci 111 (Pt 8), 1061-1069 (1998)
   PUBMED   9512502
REFERENCE   7  (bases 1 to 1183)
  AUTHORS   Zheng JY, Koda T, Arimura Y, Kishi M and Kakinuma M.
  TITLE     Structure and expression of the mouse S10 gene
  JOURNAL   Biochim Biophys Acta 1351 (1-2), 47-50 (1997)
   PUBMED   9116044
REFERENCE   8  (bases 1 to 1183)
  AUTHORS   Koda T and Kakinuma M.
  TITLE     Molecular cloning of a cDNA encoding a novel small GTP-binding
            protein
  JOURNAL   FEBS Lett 328 (1-2), 21-24 (1993)
   PUBMED   7688322
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL669901.26, BX521636.1,
            D83279.1 and AW491145.1.
            
            [WARNING] On Nov 30, 2023 this sequence was replaced by
            NM_011228.3.
            
            On Jun 7, 2013 this sequence version replaced NM_011228.1.
            
            Summary: This gene encodes a member of the Ras-related small
            GTPases, which regulate membrane trafficking in organelles and
            transport vesicles. This protein has been reported to be expressed
            in lymphocytes and in regions of the mouse brain, specifically the
            cortex, hippocampus and also the olfactory bulb. The ortholog of
            this protein in rat has been characterized and may participate in
            anterograde trafficking of synaptophysin-positive vesicles to the
            plasma membrane. [provided by RefSeq, Jun 2013].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU922072.1, D83279.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                AL669901.26        90703-90742
            41-185              BX521636.1         11-155
            186-1158            D83279.1           1-973
            1159-1183           AW491145.1         1-25                c
FEATURES             Location/Qualifiers
     source          1..1183
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 25.68 cM"
     gene            1..1183
                     /gene="Rab33a"
                     /gene_synonym="Rabs10"
                     /note="RAB33A, member RAS oncogene family"
                     /db_xref="GeneID:19337"
                     /db_xref="MGI:MGI:109493"
     exon            1..574
                     /gene="Rab33a"
                     /gene_synonym="Rabs10"
                     /inference="alignment:Splign:2.1.0"
     CDS             317..1030
                     /gene="Rab33a"
                     /gene_synonym="Rabs10"
                     /note="small GTP-binding protein S10; RAB33A, member of
                     RAS oncogene family"
                     /codon_start=1
                     /product="ras-related protein Rab-33A"
                     /protein_id="NP_035358.1"
                     /db_xref="CCDS:CCDS30110.1"
                     /db_xref="GeneID:19337"
                     /db_xref="MGI:MGI:109493"
                     /translation="MAQPILGHGSLQPASAAGLASLELDSSMDQYVQIRIFKIIVIGD
                     SNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKIKVQVWDTAGQERFRKSM
                     VEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLREQIQ
                     VPSNLALKFADAHNMLLFETSAKDPKESQNVESIFMCLACRLKAQKSLLYRDAERQQG
                     KVQKLEFSQEANGKASCPC"
     exon            575..1166
                     /gene="Rab33a"
                     /gene_synonym="Rabs10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctctcaagg ctggcccagt ctccatttct tctctctcaa gcttttgtgt ctgtgccttt
       61 gagctgaaag gagggtgcac taggaaagga ggaggggtgc ctggggtgag agcaccctct
      121 tcacgcgcgc gcgcacacac acgttgccgg cgcacgcaca cacgggcgga cacacacttc
      181 cagacgcgcg tgcgagcaca cacacataca cacacacaca cgcacaaagc tctctcgctt
      241 tgagcgcact aacgtggccg ctttctttgt gtggagccct cgagtggggt tgggacccgg
      301 gtcctgtccc ggggagatgg cacagcccat cctgggccat gggagcctgc agcccgcctc
      361 agctgctggc ttggcatcct tggagctcga ctcatcgatg gaccagtacg tgcagattcg
      421 cattttcaaa atcatcgtga ttggggattc caacgtgggc aagacctgcc tgaccttccg
      481 cttctgcggg ggtactttcc cagacaagac tgaggccact atcggtgtgg acttcaggga
      541 gaagaccgtg gaaatcgagg gcgagaagat caaggttcag gtgtgggaca cggcaggcca
      601 agaacgcttc cgtaaaagca tggttgagca ttactaccgc aacgtgcatg ccgtggtctt
      661 tgtctatgac gtcaccaaga tgacctcctt caccaactta aaaatgtgga tccaggaatg
      721 caacgggcat gctgtgcccc cactcgtccc caaggtgctt gtgggtaaca agtgtgactt
      781 gagggaacag atccaggtac cctccaactt agccctgaaa tttgctgacg ctcataacat
      841 gctcttgttt gagacatcag ccaaggaccc caaagaaagc cagaatgtgg agtcgatctt
      901 catgtgcctg gcttgccgac ttaaggccca gaaatccctc ttgtaccgtg atgccgagag
      961 gcagcaaggc aaggtgcaga aactggagtt ctcacaagag gctaacggta aagcctcctg
     1021 tccttgttga agccaaatgg tgtcaatatt cgagaattac cactggagtt tttcctttcc
     1081 cttttttctg tgcctgcata atacctacac ctgcttgttt ccatacaaac taatatcaaa
     1141 ataaaatttg tatagattat cacgtgaaaa aaaaaaaaaa aaa
//
