LOCUS       NM_026405               2054 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Mus musculus RAB32, member RAS oncogene family (Rab32), mRNA.
ACCESSION   NM_026405
VERSION     NM_026405.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2054)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2054)
  AUTHORS   Tokuda,K., Lu,S.L., Zhang,Z., Kato,Y., Chen,S., Noda,K., Hirose,K.,
            Usami,Y., Uzawa,N., Murakami,S., Toyosawa,S., Fukuda,M.,
            Sun-Wada,G.H., Wada,Y. and Noda,T.
  TITLE     Rab32 and Rab38 maintain bone homeostasis by regulating
            intracellular traffic in osteoclasts
  JOURNAL   Cell Struct Funct 48 (2), 223-239 (2023)
   PUBMED   37793839
  REMARK    GeneRIF: Rab32 and Rab38 maintain bone homeostasis by regulating
            intracellular traffic in osteoclasts.
REFERENCE   3  (bases 1 to 2054)
  AUTHORS   Noda,K., Lu,S.L., Chen,S., Tokuda,K., Li,Y., Hao,F., Wada,Y.,
            Sun-Wada,G.H., Murakami,S., Fukuda,M., Itoh,T. and Noda,T.
  TITLE     Characterization of Rab32- and Rab38-positive lysosome-related
            organelles in osteoclasts and macrophages
  JOURNAL   J Biol Chem 299 (10), 105191 (2023)
   PUBMED   37625588
REFERENCE   4  (bases 1 to 2054)
  AUTHORS   Nishizawa,A., Maruta,Y. and Fukuda,M.
  TITLE     Rab32/38-Dependent and -Independent Transport of Tyrosinase to
            Melanosomes in B16-F1 Melanoma Cells
  JOURNAL   Int J Mol Sci 23 (22), 14144 (2022)
   PUBMED   36430618
  REMARK    GeneRIF: Rab32/38-Dependent and -Independent Transport of
            Tyrosinase to Melanosomes in B16-F1 Melanoma Cells.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2054)
  AUTHORS   Balci,A., Solano-Collado,V., Baldassarre,M. and Spano,S.
  TITLE     VARP and Rab9 Are Dispensable for the Rab32/BLOC-3 Dependent
            Salmonella Killing
  JOURNAL   Front Cell Infect Microbiol 10, 581024 (2020)
   PUBMED   33392103
  REMARK    GeneRIF: VARP and Rab9 Are Dispensable for the Rab32/BLOC-3
            Dependent Salmonella Killing.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2054)
  AUTHORS   Itoh,T., Satoh,M., Kanno,E. and Fukuda,M.
  TITLE     Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16)
            domain-containing proteins based on their Rab-binding activity
  JOURNAL   Genes Cells 11 (9), 1023-1037 (2006)
   PUBMED   16923123
REFERENCE   7  (bases 1 to 2054)
  AUTHORS   Cohen-Solal,K.A., Sood,R., Marin,Y., Crespo-Carbone,S.M.,
            Sinsimer,D., Martino,J.J., Robbins,C., Makalowska,I., Trent,J. and
            Chen,S.
  TITLE     Identification and characterization of mouse Rab32 by mRNA and
            protein expression analysis
  JOURNAL   Biochim Biophys Acta 1651 (1-2), 68-75 (2003)
   PUBMED   14499590
  REMARK    GeneRIF: Data report the cloning and characterization of the mouse
            homologue of human Rab32.
REFERENCE   8  (bases 1 to 2054)
  AUTHORS   Fukuda,M.
  TITLE     Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and
            Noc2. Identification of a critical determinant of Rab3A/Rab27A
            recognition by Rim2
  JOURNAL   J Biol Chem 278 (17), 15373-15380 (2003)
   PUBMED   12578829
REFERENCE   9  (bases 1 to 2054)
  AUTHORS   Fukuda,M., Kuroda,T.S. and Mikoshiba,K.
  TITLE     Slac2-a/melanophilin, the missing link between Rab27 and myosin Va:
            implications of a tripartite protein complex for melanosome
            transport
  JOURNAL   J Biol Chem 277 (14), 12432-12436 (2002)
   PUBMED   11856727
REFERENCE   10 (bases 1 to 2054)
  AUTHORS   Kuroda,T.S., Fukuda,M., Ariga,H. and Mikoshiba,K.
  TITLE     The Slp homology domain of synaptotagmin-like proteins 1-4 and
            Slac2 functions as a novel Rab27A binding domain
  JOURNAL   J Biol Chem 277 (11), 9212-9218 (2002)
   PUBMED   11773082
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK088661.1.
            
            On Apr 5, 2007 this sequence version replaced NM_026405.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK088661.1, AK163620.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2054              AK088661.1         2-2055
FEATURES             Location/Qualifiers
     source          1..2054
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="NOD"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 3.44 cM"
     gene            1..2054
                     /gene="Rab32"
                     /gene_synonym="2810011A17Rik"
                     /note="RAB32, member RAS oncogene family"
                     /db_xref="GeneID:67844"
                     /db_xref="MGI:MGI:1915094"
     exon            1..363
                     /gene="Rab32"
                     /gene_synonym="2810011A17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             120..791
                     /gene="Rab32"
                     /gene_synonym="2810011A17Rik"
                     /codon_start=1
                     /product="ras-related protein Rab-32"
                     /protein_id="NP_080681.1"
                     /db_xref="CCDS:CCDS23695.1"
                     /db_xref="GeneID:67844"
                     /db_xref="MGI:MGI:1915094"
                     /translation="MAGEGLGQQGASATAAPETREHLFKVLVIGELGVGKTSIIKRYV
                     HQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEALGAFV
                     VFDISRSSTFDAVLKWKNDLDSKVHLPNGSPIPAVLLANKCDQKKDNSQSPSQMDQFC
                     KDHGFTGWFETSAKDNINIDEATRFLVENMLANQQSFPSEEIDLDRIKLVEEPPTTKP
                     RSQCC"
     exon            364..641
                     /gene="Rab32"
                     /gene_synonym="2810011A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            642..2054
                     /gene="Rab32"
                     /gene_synonym="2810011A17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1840..1845
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab32"
                     /gene_synonym="2810011A17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1858
                     /gene="Rab32"
                     /gene_synonym="2810011A17Rik"
                     /note="major polyA site"
ORIGIN      
        1 agactgttct gggccagcag cgcgcagtag gttccgggtc cggtgactcg cgtgactgcg
       61 cggacggagt atctgtcagg tcggcctttg gggaagaagt tccctaggcc gtggcaccca
      121 tggcgggcga gggactaggg caacagggcg cgtcggccac cgcggcgccg gagacccgag
      181 agcacctctt taaggtgctg gtcatcggcg agctcggcgt gggtaagacg agcatcatca
      241 agcgctacgt gcaccagctc ttctcccagc actaccgcgc caccattggc gtggacttcg
      301 ccctcaaagt tctcaactgg gacagcagga cgctcgtgcg cctgcagctg tgggatatcg
      361 cgggacagga acggtttggc aacatgactc gagtatacta taaggaagct cttggagcat
      421 ttgtagtctt tgatatatcg agaagttcta catttgatgc agtcctaaaa tggaaaaacg
      481 atctggatag taaagttcat cttcccaacg gcagccccat tcctgctgtc ctcctagcta
      541 acaaatgtga ccagaagaag gacaacagcc agagtccttc ccagatggac cagttttgta
      601 aagaccatgg cttcactgga tggtttgaaa cctctgccaa ggataatata aacatcgacg
      661 aggccacccg cttcctagtg gaaaacatgc ttgcaaacca gcaaagtttt cctagtgaag
      721 aaatcgacct ggacagaatt aaactggtag aggagccccc cacaacaaag cccaggtccc
      781 agtgctgctg atgtgtctct gtgccccatg tgctgtctcc ttggtcctgc ctgtatggag
      841 gctgcccctt tccaaccctc ggtgccactg tgccctgtga ctctccctcg gggggcgctg
      901 ctttaccgtt cagctgtaca ggcaccgccc atctgaagat ccatggagaa ctgttcccat
      961 gagaggccct gtgactttac ccgaggaccc ctcaggctct tgtcatactg ccaaatgcaa
     1021 actaatgttt acagcctttg aaatattttt gtacatgaat ttcaaaagtt agcttttagt
     1081 gtgagtccta ggtggggtca tagaaaaggt cccctcggcc tggtgatggt gattgtgact
     1141 tttcagtgac tttgttcctg tatacatcct cacctaagca catttatttt ttcttttcta
     1201 aggtgttagc tacagagacc tgaaggtcac gtgcagttat atcctagtca aaactttgta
     1261 cgtcacgtaa aattttcatc cttaaataac atgattccat aacacatagc tgttgtacaa
     1321 tgaagtcact ctgactcacc ttaagaacac cttctttaat tagtcaaaaa gtcccgagct
     1381 aggaatgtgg ctcatttatg tagagtgctt acctagaatg cgatagactc tctgggtctg
     1441 cagttctgag agaccaaaaa gagttagcac catacctgtt ttatgtgtgt ctccttctgg
     1501 atcctctctc ggtgtggttg ccactaccac ttggaaacaa tataaatgaa gattttgttt
     1561 ctctgccctc tattctgtac ttatagccta gggccatatt gaacatacag tggtactaag
     1621 aggaacttgt ctttccggtt ctgtcataat aataatggtc aggaggggaa ttctttttca
     1681 aaacatatgc aattatagcc aagtttctgt agtgtaaaac ctggaagaaa gtagaccatg
     1741 tctagttttg tctgtggttt ctaatactgg ttatataatg cctcgggcac ttaggaagac
     1801 ccactatact gtattgcctt taactcagtg aaagaaagga ataaatattt taacctaagc
     1861 ctgtgtgttg aatgaatgtg gttagttcta ggaaggaact gttctggttt agaaaatgtg
     1921 tttggctgag gtggtggttc acatctgtca tcccagcctg caggagacag agacaaaggg
     1981 tgggagtgca tatcttggct acattgcaag ttcaagaata gccggtgcta cacaagaggc
     2041 tttctcccaa aatt
//
