LOCUS       NM_029494               2007 bp    mRNA    linear   ROD 11-JUN-2024
DEFINITION  Mus musculus RAB30, member RAS oncogene family (Rab30), mRNA.
ACCESSION   NM_029494
VERSION     NM_029494.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2007)
  AUTHORS   Smith,D.M., Liu,B.Y. and Wolfgang,M.J.
  TITLE     Rab30 facilitates lipid homeostasis during fasting
  JOURNAL   Nat Commun 15 (1), 4469 (2024)
   PUBMED   38796472
  REMARK    GeneRIF: Rab30 facilitates lipid homeostasis during fasting.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2007)
  AUTHORS   Liang,Y., Lin,S., Zou,L., Zhou,H., Zhang,J., Su,B. and Wan,Y.
  TITLE     Expression profiling of Rab GTPases reveals the involvement of
            Rab20 and Rab32 in acute brain inflammation in mice
  JOURNAL   Neurosci Lett 527 (2), 110-114 (2012)
   PUBMED   22960262
  REMARK    GeneRIF: Rabs may participate in inflammatory response in microglia
            during brain inflammation.
REFERENCE   3  (bases 1 to 2007)
  AUTHORS   Chiba,M., Murata,S., Myronovych,A., Kohno,K., Hiraiwa,N.,
            Nishibori,M., Yasue,H. and Ohkohchi,N.
  TITLE     Elevation and characteristics of Rab30 and S100a8/S100a9 expression
            in an early phase of liver regeneration in the mouse
  JOURNAL   Int J Mol Med 27 (4), 567-574 (2011)
   PUBMED   21308349
  REMARK    GeneRIF: Rab30 and S100a8/S100a9 were indicated to play roles in
            the initiation of liver regeneration as well as possibly in the
            functional switch of the liver in the newborn stage.
REFERENCE   4  (bases 1 to 2007)
  AUTHORS   Itoh,T., Satoh,M., Kanno,E. and Fukuda,M.
  TITLE     Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16)
            domain-containing proteins based on their Rab-binding activity
  JOURNAL   Genes Cells 11 (9), 1023-1037 (2006)
   PUBMED   16923123
REFERENCE   5  (bases 1 to 2007)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   6  (bases 1 to 2007)
  AUTHORS   Fukuda,M.
  TITLE     Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and
            Noc2. Identification of a critical determinant of Rab3A/Rab27A
            recognition by Rim2
  JOURNAL   J Biol Chem 278 (17), 15373-15380 (2003)
   PUBMED   12578829
REFERENCE   7  (bases 1 to 2007)
  AUTHORS   Fukuda,M., Kuroda,T.S. and Mikoshiba,K.
  TITLE     Slac2-a/melanophilin, the missing link between Rab27 and myosin Va:
            implications of a tripartite protein complex for melanosome
            transport
  JOURNAL   J Biol Chem 277 (14), 12432-12436 (2002)
   PUBMED   11856727
REFERENCE   8  (bases 1 to 2007)
  AUTHORS   Kuroda,T.S., Fukuda,M., Ariga,H. and Mikoshiba,K.
  TITLE     The Slp homology domain of synaptotagmin-like proteins 1-4 and
            Slac2 functions as a novel Rab27A binding domain
  JOURNAL   J Biol Chem 277 (11), 9212-9218 (2002)
   PUBMED   11773082
REFERENCE   9  (bases 1 to 2007)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC017550.1.
            
            On Jun 10, 2003 this sequence version replaced NM_029494.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC017550.1, AK142206.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2007
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 51.6 cM"
     gene            1..2007
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /note="RAB30, member RAS oncogene family"
                     /db_xref="GeneID:75985"
                     /db_xref="MGI:MGI:1923235"
     exon            1..129
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /inference="alignment:Splign:2.1.0"
     exon            130..230
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /inference="alignment:Splign:2.1.0"
     CDS             138..749
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /codon_start=1
                     /product="ras-related protein Rab-30"
                     /protein_id="NP_083770.2"
                     /db_xref="CCDS:CCDS21450.1"
                     /db_xref="GeneID:75985"
                     /db_xref="MGI:MGI:1923235"
                     /translation="MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGV
                     DFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPE
                     WLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVE
                     KLFLDLACRLISEARQNTLVNNVSSPLPGEGKSISYLTCCNFN"
     exon            231..314
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /inference="alignment:Splign:2.1.0"
     exon            315..498
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /inference="alignment:Splign:2.1.0"
     exon            499..1927
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1313..1318
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /note="hexamer: AGTAAA"
     polyA_site      1336
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /note="major polyA site"
     regulatory      1433..1438
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /note="hexamer: AATAAA"
     polyA_site      1454
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /note="major polyA site"
     regulatory      1897..1902
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
                     /note="hexamer: AATAAA"
     polyA_site      1924
                     /gene="Rab30"
                     /gene_synonym="5033421K01Rik; Rsb30"
ORIGIN      
        1 gcaggaccag ggcagggact gactccagtc cttggactta ggacaccgca gcaccttctc
       61 ttgcgtgcgt gactcattcg tatatcattt ctttttatgc ctggggtggg gagaaaaatc
      121 ccaaaccagc tgtgtaaatg agtatggaag attatgattt cctgttcaaa attgttttaa
      181 ttggcaacgc tggagtggga aagacgtgcc tagtccgaag attcactcag ggtcttttcc
      241 ccccaggtca aggagccaca attggagttg attttatgat taagacagtg gagattaatg
      301 gtgaaaaagt gaagttacag atctgggaca ccgcaggtca agagagattt cgctccatca
      361 ctcaaagtta ctatcgaagc gccaatgcct tgatccttac ctatgacatc acctgtgagg
      421 aatccttccg ctgccttcct gagtggttgc gggagataga acagtatgct agcaataaag
      481 tcatcactgt gttagtaggc aacaagattg acctggctga aaggcgagag gtctcccagc
      541 agagagcaga agagttctca gaggctcagg acatgtatta cctggagact tcagccaagg
      601 aatccgacaa tgtggagaaa ctcttccttg acttagcatg ccgactcatc agcgaagcaa
      661 gacagaacac actggtgaac aatgtatcgt cacccttacc cggagagggg aaaagcatca
      721 gctatttgac ttgttgtaat ttcaactaaa ggctgaggca aagagaatca aagggaatca
      781 gtagttgcct tggtgggccg tacgttgcta gggaatctgg caatgactat ggctcccgct
      841 cttggacctt ctgactcctg taggctccag agcttaccaa gcatgcaggc caagggcctt
      901 gactgcaggc cagcattagc agaacacata atggtttcac ccttttgcag tctggcgttg
      961 gagcaaggag aaaattgcac taagcgctcc atgatctgca gagcatgttg cttttgtttt
     1021 taaaaaagca agtaaaaaat gcattcctga acacagagca ggggatcgtg tactgtagga
     1081 atccttctgt gtgtcagcgg gtgcatgagg ggctattctt taggcttcag tggtaatctg
     1141 gtgcccatgg atttcttgac taccaggtaa accaaaactg gaaaggccaa gtactgtctc
     1201 tgtagtactt attgaggacc ccatggagat tttgaaaagt gttatttctt ttgtccacaa
     1261 gcactttcaa aacctttggg atataaaaat gggaactctt ctcacgacca acagtaaaaa
     1321 ttattgttta acaatatata caagctccat gactcttttt ggtgctaatg attatgctat
     1381 ttcacagacc aaacgtttta gtacattgat acccttagat gtattaccta aaaataaaaa
     1441 gagaatgggg gaaatccatg agtcagcagt cttcttcagt ctcattacca ccatttctag
     1501 gatgggtttg gatatgagaa gcccttcttc tttcatattc tccttgaaat ttattaacat
     1561 tcttctattc tttcacactt atcgtgccct ttaggtaaat caaagtatta aaaaaatggg
     1621 gaaaaatata aattatgaca ttctaataaa gaagattagt tgtaggacat gttgagtagc
     1681 atgagaaaac agagcagata tgaccaaaat actgtggact atggactgac tgcagggcag
     1741 acttccagac agagtgcagc tctctaacag gtcacgcctt ttcctttcgg gaactagcct
     1801 tggagaggcc aaggtttagg attttgtaga catttttagt ataataagtg agaatagcaa
     1861 gagatgaaaa gtctcacaaa tcatttttgt atcttcaata aacttaggaa agtgtgctca
     1921 ggaagcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1981 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
