LOCUS       NM_144875               1212 bp    mRNA    linear   ROD 10-MAR-2023
DEFINITION  Mus musculus RAB29, member RAS oncogene family (Rab29), mRNA.
ACCESSION   NM_144875
VERSION     NM_144875.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1212)
  AUTHORS   Mazza MC, Nguyen V, Beilina A, Karakoleva E, Coyle M, Ding J,
            Bishop C and Cookson MR.
  TITLE     Combined Knockout of Lrrk2 and Rab29 Does Not Result in Behavioral
            Abnormalities in vivo
  JOURNAL   J Parkinsons Dis 11 (2), 569-584 (2021)
   PUBMED   33523017
REFERENCE   2  (bases 1 to 1212)
  AUTHORS   Kalogeropulou AF, Freemantle JB, Lis P, Vides EG, Polinski NK and
            Alessi DR.
  TITLE     Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway
            activity
  JOURNAL   Biochem J 477 (22), 4397-4423 (2020)
   PUBMED   33135724
  REMARK    GeneRIF: Endogenous Rab29 does not impact basal or stimulated LRRK2
            pathway activity.
REFERENCE   3  (bases 1 to 1212)
  AUTHORS   Beilina A, Bonet-Ponce L, Kumaran R, Kordich JJ, Ishida M, Mamais
            A, Kaganovich A, Saez-Atienzar S, Gershlick DC, Roosen DA,
            Pellegrini L, Malkov V, Fell MJ, Harvey K, Bonifacino JS, Moore DJ
            and Cookson MR.
  TITLE     The Parkinson's Disease Protein LRRK2 Interacts with the GARP
            Complex to Promote Retrograde Transport to the trans-Golgi Network
  JOURNAL   Cell Rep 31 (5), 107614 (2020)
   PUBMED   32375042
REFERENCE   4  (bases 1 to 1212)
  AUTHORS   Kuwahara T, Inoue K, D'Agati VD, Fujimoto T, Eguchi T, Saha S,
            Wolozin B, Iwatsubo T and Abeliovich A.
  TITLE     LRRK2 and RAB7L1 coordinately regulate axonal morphology and
            lysosome integrity in diverse cellular contexts
  JOURNAL   Sci Rep 6, 29945 (2016)
   PUBMED   27424887
  REMARK    GeneRIF: LRRK2 functions together with a second Parkinson's
            disease-associated gene, RAB7L1, within an evolutionarily conserved
            genetic module in diverse cellular contexts.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1212)
  AUTHORS   Onnis A, Finetti F, Patrussi L, Gottardo M, Cassioli C, Spano S and
            Baldari CT.
  TITLE     The small GTPase Rab29 is a common regulator of immune synapse
            assembly and ciliogenesis
  JOURNAL   Cell Death Differ 22 (10), 1687-1699 (2015)
   PUBMED   26021297
REFERENCE   6  (bases 1 to 1212)
  AUTHORS   MacLeod DA, Rhinn H, Kuwahara T, Zolin A, Di Paolo G, McCabe BD,
            Marder KS, Honig LS, Clark LN, Small SA and Abeliovich A.
  TITLE     RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting
            and Parkinson's disease risk
  JOURNAL   Neuron 77 (3), 425-439 (2013)
   PUBMED   23395371
  REMARK    Erratum:[Neuron. 2013 Mar 6;77(5):994. MacCabe, Brian D [corrected
            to McCabe, Brian D]]
REFERENCE   7  (bases 1 to 1212)
  AUTHORS   Itoh T, Satoh M, Kanno E and Fukuda M.
  TITLE     Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16)
            domain-containing proteins based on their Rab-binding activity
  JOURNAL   Genes Cells 11 (9), 1023-1037 (2006)
   PUBMED   16923123
REFERENCE   8  (bases 1 to 1212)
  AUTHORS   Fukuda M.
  TITLE     Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and
            Noc2. Identification of a critical determinant of Rab3A/Rab27A
            recognition by Rim2
  JOURNAL   J Biol Chem 278 (17), 15373-15380 (2003)
   PUBMED   12578829
REFERENCE   9  (bases 1 to 1212)
  AUTHORS   Fukuda M, Kuroda TS and Mikoshiba K.
  TITLE     Slac2-a/melanophilin, the missing link between Rab27 and myosin Va:
            implications of a tripartite protein complex for melanosome
            transport
  JOURNAL   J Biol Chem 277 (14), 12432-12436 (2002)
   PUBMED   11856727
REFERENCE   10 (bases 1 to 1212)
  AUTHORS   Kuroda TS, Fukuda M, Ariga H and Mikoshiba K.
  TITLE     The Slp homology domain of synaptotagmin-like proteins 1-4 and
            Slac2 functions as a novel Rab27A binding domain
  JOURNAL   J Biol Chem 277 (11), 9212-9218 (2002)
   PUBMED   11773082
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AI047619.1, BG087764.2, AK079752.1 and CK796080.1.
            
            [WARNING] On May 18, 2023 this sequence was replaced by
            NM_144875.3.
            
            On May 8, 2009 this sequence version replaced NM_144875.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC016133.1, SRR5189670.2222.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-272               AI047619.1         1-272
            273-601             BG087764.2         272-600
            602-1158            AK079752.1         456-1012
            1159-1212           CK796080.1         3-56                c
FEATURES             Location/Qualifiers
     source          1..1212
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1"
     gene            1..1212
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /note="RAB29, member RAS oncogene family"
                     /db_xref="GeneID:226422"
                     /db_xref="MGI:MGI:2385107"
     exon            1..134
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     exon            135..391
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             268..882
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /note="rab-7-like protein 1; RAB7, member RAS oncogene
                     family-like 1"
                     /codon_start=1
                     /product="ras-related protein Rab-7L1"
                     /protein_id="NP_659124.2"
                     /db_xref="CCDS:CCDS15276.1"
                     /db_xref="GeneID:226422"
                     /db_xref="MGI:MGI:2385107"
                     /translation="MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDF
                     ALKVLQWSDSEMVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRW
                     KQDLDSKLTLPSGEPVPCLLLANKSDLSPWAVSRDQIDQFSKENGFTGWTETSVKENK
                     NINEAMRVLVEKMMNNSREDVMSLSTQGNYINLQAKPSSGWTCC"
     exon            392..463
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     exon            464..645
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     exon            646..767
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
     exon            768..1189
                     /gene="Rab29"
                     /gene_synonym="Rab7l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggacaagga ctctgcacaa cctcaatttt gtgtgtgcgg tccgagaaag ggtctaagtc
       61 atctgtactt ctctaagcaa ggtgctggcc acggttcaat gctggcgagc gactcggagg
      121 tccctgaaag gaagtcagag aagcttcaac caaccgaggg tggagatgcc tgacttcaat
      181 tggaagagaa cccgggagcc aaaggggttg aaataagcga cttcccggaa aaacaaacta
      241 tcaaaaaacc tctccccacc actagccatg ggcagccgag atcacctgtt taaagtgctg
      301 gtggtggggg acgccgccgt tggcaagacg tctctggtcc agcgctactc ccaggacagc
      361 ttcagcaagc actacaagtc caccgtggga gtggattttg ctctcaaggt tctccagtgg
      421 tctgactcag agatggtgcg gctgcagctc tgggatattg cagggcagga gcgtttcaca
      481 tccatgacac gactctacta tagagatgct tctgcctgtg ttattatgtt tgacgtcacc
      541 aatgccacta ctttcagcaa cagccaaaga tggaaacagg atctggacag caagctcaca
      601 ctacccagtg gggagccagt gccctgcctg ctcttggcca acaagagtga tctgtcccct
      661 tgggcagtga gccgggacca gatcgaccag ttcagtaaag agaatggctt cacaggttgg
      721 acagaaacat cagtcaagga gaacaaaaat attaatgagg ccatgagagt cctcgttgaa
      781 aagatgatga acaattccag ggaagatgtg atgtctttgt ccacccaagg gaactacatc
      841 aatctccaag ccaagccctc ctctggctgg acatgctgct agttctgttt ggctcctttt
      901 ctatccaggt ctctgagtca ttccaattct tcctgttgga tgccagcctg gcataaaagt
      961 tccgttgaga atattcaata ttctcttgcc aatggcctgg aaaggagccc ccctgtgact
     1021 tgggaatggc tgcctgggac ccatgtgcat ctgcgttgtt cttgggtgtc gtctgtgact
     1081 tactgatgtc ccgtgtacta tagctagtat tttctgtgtg acagtgatca cctcattcct
     1141 cgactgtgag atgagtttat gaaaagaatt aaaagtgagc acttgtgaaa aaaaaaaaaa
     1201 aaaaaaaaaa aa
//
