LOCUS       NM_030554               7212 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RAB27B, member RAS oncogene family (Rab27b),
            transcript variant 1, mRNA.
ACCESSION   NM_030554
VERSION     NM_030554.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7212)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7212)
  AUTHORS   Richard,A.C., Ma,C.Y., Marioni,J.C. and Griffiths,G.M.
  TITLE     Cytotoxic T lymphocytes require transcription for infiltration but
            not target cell lysis
  JOURNAL   EMBO Rep 24 (11), e57653 (2023)
   PUBMED   37860838
REFERENCE   3  (bases 1 to 7212)
  AUTHORS   Ren,J.G., Xing,B., Lv,K., O'Keefe,R.A., Wu,M., Wang,R., Bauer,K.M.,
            Ghazaryan,A., Burslem,G.M., Zhang,J., O'Connell,R.M., Pillai,V.,
            Hexner,E.O., Philips,M.R. and Tong,W.
  TITLE     RAB27B controls palmitoylation-dependent NRAS trafficking and
            signaling in myeloid leukemia
  JOURNAL   J Clin Invest 133 (12), e165510 (2023)
   PUBMED   37317963
  REMARK    GeneRIF: RAB27B controls palmitoylation-dependent NRAS trafficking
            and signaling in myeloid leukemia.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7212)
  AUTHORS   Bauer,K.M., Nelson,M.C., Tang,W.W., Chiaro,T.R., Brown,D.G.,
            Ghazaryan,A., Lee,S.H., Weis,A.M., Hill,J.H., Klag,K.A., Tran,V.B.,
            Thompson,J.W., Ramstead,A.G., Monts,J.K., Marvin,J.E.,
            Alexander,M., Voth,W.P., Stephens,W.Z., Ward,D.M., Petrey,A.C.,
            Round,J.L. and O'Connell,R.M.
  TITLE     CD11c+ myeloid cell exosomes reduce intestinal inflammation during
            colitis
  JOURNAL   JCI Insight 7 (19), e159469 (2022)
   PUBMED   36214220
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7212)
  AUTHORS   Pattanayak,R., Underwood,R., Crowley,M.R., Crossman,D.K.,
            Morgan,J.R. and Yacoubian,T.A.
  TITLE     Deletion in chromosome 6 spanning alpha-synuclein and multimerin1
            loci in the Rab27a/b double knockout mouse
  JOURNAL   Sci Rep 12 (1), 9837 (2022)
   PUBMED   35701443
  REMARK    GeneRIF: Deletion in chromosome 6 spanning alpha-synuclein and
            multimerin1 loci in the Rab27a/b double knockout mouse.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7212)
  AUTHORS   Barral,D.C., Ramalho,J.S., Anders,R., Hume,A.N., Knapton,H.J.,
            Tolmachova,T., Collinson,L.M., Goulding,D., Authi,K.S. and
            Seabra,M.C.
  TITLE     Functional redundancy of Rab27 proteins and the pathogenesis of
            Griscelli syndrome
  JOURNAL   J Clin Invest 110 (2), 247-257 (2002)
   PUBMED   12122117
  REMARK    GeneRIF: Rab27b is functionally redundant with Rab27a and the
            pathogenesis of Griscelli syndrome is determined by the relative
            expression of Rab27a and Rab27b in specialized cell types.
            Erratum:[J Clin Invest 2002 Oct;110(8):1213]
REFERENCE   7  (bases 1 to 7212)
  AUTHORS   Chen,Y., Samaraweera,P., Sun,T.T., Kreibich,G. and Orlow,S.J.
  TITLE     Rab27b association with melanosomes: dominant negative mutants
            disrupt melanosomal movement
  JOURNAL   J Invest Dermatol 118 (6), 933-940 (2002)
   PUBMED   12060386
  REMARK    GeneRIF: Rab27b may regulate the outward movement of melanosomes
            and the formation or maintenance of dendritic extensions in
            melanocytes.
REFERENCE   8  (bases 1 to 7212)
  AUTHORS   Zhao,S., Torii,S., Yokota-Hashimoto,H., Takeuchi,T. and Izumi,T.
  TITLE     Involvement of Rab27b in the regulated secretion of pituitary
            hormones
  JOURNAL   Endocrinology 143 (5), 1817-1824 (2002)
   PUBMED   11956164
  REMARK    GeneRIF: Rab27b is involved in pituitary hormone secretion
REFERENCE   9  (bases 1 to 7212)
  AUTHORS   Fukuda,M., Kuroda,T.S. and Mikoshiba,K.
  TITLE     Slac2-a/melanophilin, the missing link between Rab27 and myosin Va:
            implications of a tripartite protein complex for melanosome
            transport
  JOURNAL   J Biol Chem 277 (14), 12432-12436 (2002)
   PUBMED   11856727
REFERENCE   10 (bases 1 to 7212)
  AUTHORS   Ramalho,J.S., Tolmachova,T., Hume,A.N., McGuigan,A.,
            Gregory-Evans,C.Y., Huxley,C. and Seabra,M.C.
  TITLE     Chromosomal mapping, gene structure and characterization of the
            human and murine RAB27B gene
  JOURNAL   BMC Genet 2, 2 (2001)
   PUBMED   11178108
  REMARK    GeneRIF: Chromosomal mapping and gene structure of the RAB27B gene.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163398.5, BY228140.1, BY721478.1, AC108433.9, AK049854.1,
            AK161136.1 and AW455378.1.
            
            On Nov 15, 2014 this sequence version replaced NM_030554.3.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1). Variants 1, 2, and 3 encode the same protein (isoform 1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB067775.1, BC032928.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-219               AC163398.5         80939-81157         c
            220-463             BY228140.1         2-245
            464-836             BY721478.1         133-505
            837-945             AC108433.9         176517-176625       c
            946-961             BY721478.1         614-629
            962-1771            AK049854.1         633-1442
            1772-2041           AC108433.9         173887-174156       c
            2042-4648           AK049854.1         1715-4321
            4649-5770           AK161136.1         1590-2711
            5771-5771           AC108433.9         170157-170157       c
            5772-7191           AK161136.1         2713-4132
            7192-7212           AW455378.1         1-21                c
FEATURES             Location/Qualifiers
     source          1..7212
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 43.89 cM"
     gene            1..7212
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /note="RAB27B, member RAS oncogene family"
                     /db_xref="GeneID:80718"
                     /db_xref="MGI:MGI:1931295"
     exon            1..463
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            464..635
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             483..1139
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /EC_number="3.6.5.2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ras-related protein Rab-27B"
                     /codon_start=1
                     /product="ras-related protein Rab-27B isoform 1"
                     /protein_id="NP_085031.3"
                     /db_xref="CCDS:CCDS29331.1"
                     /db_xref="GeneID:80718"
                     /db_xref="MGI:MGI:1931295"
                     /translation="MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGI
                     DFREKRVVYDTQGADGASGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLT
                     SQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELAEKYGIPYF
                     ETSAATGQNVEKSVETLLDLIMKRMEKCVEKTQVPDTVNGGNSGKLDGEKPAEKKCAC
                     "
     exon            636..721
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            722..825
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            826..949
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            950..7196
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2649..2654
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /note="hexamer: AATATA"
     polyA_site      2671
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /note="major polyA site"
     regulatory      7171..7176
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      7196
                     /gene="Rab27b"
                     /gene_synonym="2310021G14Rik; B130064M09Rik"
ORIGIN      
        1 agccagggaa gtaagtcaat gaaaatgagc ctgccaccag ggcatgcact ccctcagcgt
       61 ggagaatcca ccagcagcca agtgtgattc ttattgcagg gttgagtcac cagccagact
      121 ggctcgaggt gagccaggca catccgcgtt aggactcagg gacacgcctt cttctcacac
      181 agaccttcct gatcccagcc gcctaggcgg actccagcca gggtggtgct accagccttg
      241 ccacttgcag tcttgacagg cagaggttgg ggactgtctg gccttgcaac gatcgatcag
      301 cagccacagg ttgcagacgc aaggagcagt gcccatgacc gcgactctgt gaggctggct
      361 gccggcgcgc ggtggttgct ggcgggtacc cggagctcgg gaagaccgga gcgggccccg
      421 aaacctgaca ccagagccct cgctgccccc gctccgcggg ctggccctcc aagaccatca
      481 ctatgactga tggagactat gattatctga ttaaactcct ggcccttgga gactcaggag
      541 tcgggaagac aacatttctc tatagataca cagacaataa attcaatccc aaattcatca
      601 ccacagtggg aatagatttt cgggaaaaac gtgtggttta tgacacacaa ggagcagatg
      661 gagcgtcagg aaaagcgttt aaggtacatc tgcagctttg ggacactgct ggacaagagc
      721 ggttccggag ccttaccact gccttcttca gagatgccat gggcttctta ctgatgtttg
      781 acctcaccag tcaacagagc ttcttgaatg tcagaaactg gatgagtcaa ctgcaggcaa
      841 atgcttactg tgaaaaccca gacatagtat taattggcaa caaggcagac ctgccagacc
      901 aaagggaagt caatgaacgg caagcacggg agctggctga aaaatatggc ataccatact
      961 tcgaaacaag cgcagctaca ggacagaatg tagagaagtc agtggaaacg cttctggact
     1021 taatcatgaa gagaatggaa aagtgtgtag agaagacaca ggttccggac actgtcaatg
     1081 gaggaaattc tggaaagctg gatggggaaa agccagcaga aaagaaatgt gcctgctaga
     1141 cactcagagg aaccagtgat ggagagccca cccaagtccg acgtcctgag acaatgtcaa
     1201 accatgatgt tgtcattgag cagtagctca tgagcaatgg catgtctttc tcccctgacc
     1261 ccaatctatt ttaataaagc agagtagtca tagtgttgaa agaactgtac tgttatcccg
     1321 agtcccttcc aaacaaaaaa ggcaaagttg tcctaaggtg atctcactgt tgtgaatgcc
     1381 cagttgtatt tttataaggt tgtatatatg gggaaaaaaa gtatcggtga gttttaaatg
     1441 aaagcacata ttactgccag cgtggagaga ggaagagtct aattaaaggg aggatataaa
     1501 aggatgattt ctgttttcat ctacttatgt ggagtatgac tcacacttct atatttgcac
     1561 tggggaagac atattcctaa aaatggatac ataacaaaga attctctgtg acttattaag
     1621 aatgactgtg tctgcccagt aacctgttct gagttactgg taaagtcgtg ggtgggtgaa
     1681 tggcaggctt ctgtaggaac ttgtgtaatt atgccatttt tatattccta ataaatggca
     1741 aagagacaag aataggacct tggatggaaa ttccctggca gaaaatgaaa catgggaata
     1801 agatgcttga acaagttaga tgaaatggat ctttgagata agtctgagag acagagttac
     1861 ttagacaaat gacactgaag cagattagaa gctagtatca cccattggga ttggcaatgc
     1921 cttcaaaggc tcctagtcaa atgatccaaa cctttaacat cgtttctgat ggtacccaag
     1981 ttcacatttt atttttattt tttatcaaat tcttagaaag agtcataaga aaaaaaaaaa
     2041 gacattttat tgtaaataac ttacaagtga aattaagaaa acataagatt tagtcttaca
     2101 gtttctaaat atatgatttg ttgttgagag aaaacagtga ttgttaatta tggcttttac
     2161 ttcattttag aaaagcacta gaaattctaa atttactttt cctctagacc acacttaatg
     2221 cctgccttga agacattaca gaaatgaagg tgtgttcatg ggtcaataac agcaaagtaa
     2281 ttatggacca ataactatgt tcaccctgaa acttttatgc caccaatcac caaaaattga
     2341 taccacattc tttattataa tgctttatac tttgccagga agaagtatag ctatagttga
     2401 ggtgtaccta agaaattagc aagaatggat ctgcgtctca gctcagcaga actatagcca
     2461 atgttttgtt ttgttttcct gaatgctatc ttattttttt tcttatagaa ttaatcacag
     2521 gtcttcttat cattgtgaaa actcatgttg tattactttt tattaattgt aatttgggat
     2581 acatataagt taatcttatc aaataatatt taaaattgtc aatcaatttt accaataaca
     2641 aagccaataa tatactgtta acaaagacaa actgcttcga gttttctgtt ttcgtagtga
     2701 gcttaaaatg catgacagga tagtttctca ttctttgaaa cattttcagt ctcaaacttt
     2761 ctgcatactt tgcctccttt aaaagttaca aatattacaa agtaaaatct agcgtcatat
     2821 ccaattcttc caaatgacct ctatcagctg ttgagtcaga cagatccacg gacatgtcta
     2881 ccaaaaaatg atgtggaggt ttaggtggga ttcaccctta gtacaattct tagtgtcaat
     2941 agcacagcac cccagcttgt acaagtcatt ctctgttagg attcctttca attctcactg
     3001 tctacaatgc tcttcatggt ctcaatgtct gtgccataag ggtagaaagc taacagtcag
     3061 tttttgcaac ctgtcttctg gaagcaaagt gaaaagaaat gaccagggct atggcaaaat
     3121 ctggtgaatg tcgtgagctc tcctacatct atttccggtt ttgattccag tcataccagt
     3181 atttccataa cagagaatgg tgagccctat gatgctgaag ggattccatc tctccatctc
     3241 ccagtttatc attgtggtcc aattacatag tcagctacat aattggcttg cttatacaaa
     3301 gataagcaag agtctttcat tgtcagaata agtatttttc acgatctgtt tgaagagcat
     3361 cattgctaac tagcatgaag cagagggcaa tgatgcctgt aaatatgaaa atgtgcctgt
     3421 aagagtaaca ggtatcgctg ggcagtggtg gcacacgcct ttaatcccag caattgggag
     3481 gcagaggcag gtggatttct aagtttgagg ccaacctggt ctacagagtg agttccagga
     3541 cagccagggc tacacagaga aaccctgtct ttaaaaaaat aaataaataa aagttacagg
     3601 tattgggtaa taagctcaag agggttgaca tttcaaactg ccaaaaatga aaatattcta
     3661 gttattaaac tcttggtcta gaaatacttc tgtctgtaaa ctttgacatc caacctggaa
     3721 atctatttgg tcatggttaa aacattattc tcctatgata ttcagattct agttctatat
     3781 acttcattat ataactttga attgatctgg tgccatgact tttctacttt caagaactat
     3841 gtatctcttt tatcccacca caacatttat ctgtagctaa gatattttct cttaataatt
     3901 acctcccaaa tgcttttagt gaaccgactg tatttttccg aggtatctcg tgtacatggt
     3961 acttctttct gctacagccg ccaagtctag agtgtttaca ctggttgatg cttacacagc
     4021 ctgaactcag tgcctcaaac tcctctgtga ccagttttgt ctccaagcac ataactcatt
     4081 ctctctaatc tgatgtctct gaagagcctc acagagacag tggtatggct gaacccatcg
     4141 gatattgtta gcaaaggatg caaaaacatt attggcatct ggagattatt gcaacgttct
     4201 cctaacctgt cacagaaagc agttgcttga aaattagcca caaattggta caatgttatt
     4261 tcaatcttat ataaaaatgg tcttctgaaa aatctataaa acaggcctga gaagatagtt
     4321 ctggtcttgt tctgactgtg gtaactagct gtgaccaaga agagaaaatg ttgtgtcttg
     4381 ggaaatgaac ttggatctct ccataatggt ttcaacattc aaactttact acttaagtca
     4441 atatactaat aatttactgc taattaaccc cacagaacta gcattttcta aagtatgtaa
     4501 tctgttaatt tttaaccaga taaggctttc tatgcatcca caggtgcctt tgttttaact
     4561 gtggatttat tgattgctaa cctctacaga tatgatgata gggcaagcat tcttctaatc
     4621 gattttaatt gtcctttgtg tgaaaaacaa aacaaaacaa acaaaaaaac ccagaaactt
     4681 atccataaat aactacatga cagcattaaa atctgtagca aagagatata aactctagag
     4741 tgagtctatt gggaatcagc agattataca tacctggggc atcttctcaa ctagtgcgca
     4801 ggagcaccag gtagaggcag ctgtgtgtgg agatgcagtg tgttcctaga gaaggtgaac
     4861 aacctgaaag cgcctgtgaa gggaaccagt cactcttctg tacctctctt ctcttagaga
     4921 aaaaaatgcc ttccttgctt tgtatcatac ccaatattta aggacaattt gtcactcaga
     4981 ggactttaga gttatattcc aacattcaac ctatagataa gaaacatttc taacctttgg
     5041 tttgctgaca tgtgtagtaa ctctctaaaa tgtctggaga tgggcaagga agatgcaggg
     5101 cctctgaata gtagatgtga gaacttgggt ttggtcctca ggtaacagag agggtgaagg
     5161 ggagaggagg agctagtatt agccaaagtg atagaaaacc tgattttcat ctcgtactac
     5221 caagctttac aacattgaaa gtggcctagt aactctgagt attttaaaga atgctttatc
     5281 attttttaaa gatgtcaaga aactagctat agctgcctaa gaattgaatc tattgtattt
     5341 ccctcttgat attctaccat ggtgatgtca gctcatttct aagatgcctt cagagatctg
     5401 agacatgaca ttaagaatgg agtagtaact agagtgttat ctcagtgcct gtctcatagt
     5461 atagaaatga caagcactgc tggctataga gaaaatgtta taaaaattgt cattgaattc
     5521 tttaatggtg tccaaccacg atgatattgc tgatcaaaag ttatgaacag aaataagagt
     5581 gacagctagc taagtcaagc ttttcaatag aggagaaaat aaagatggcg acaggttggc
     5641 ttaggtggag gaagaaaaga gttatcattt ttagactaaa tccacgcatg aaaaatattt
     5701 cctcattatt cttatctgct tagtggattt tatgccctta taactaagta aagaaaattt
     5761 atgactacca aatatttagg atacttagaa atattttact acatatgaat ctgatattct
     5821 taataaagta ttactttaaa ttttccagca gtaacattta gagattcttt atagaaatgt
     5881 cctctgcacc aacagtttat ggctgagatg ttttgtaatt tcatgatgtt tgtaattttc
     5941 atgaaaatgt gtgattttcg tttgtgatat gaaagatcat taatcaaaga ataaggaaga
     6001 aacaaggtaa aacagtccta aaatgatgga actatttaaa agggtgtcaa ctcttaagag
     6061 aacacctgtg gtttaaatgt tctttttctg cttccttttc tatctgagag gtcctaacca
     6121 ttacagctat cacccctcgg ctgacatggt ctttcaagat tcttagtagg tctctcagaa
     6181 gccagttcat ctggccttaa ctgaatggat tccctattta accagaaact gttgtcctcc
     6241 tgctaaacac tgtctgttaa gggactcagt catatatgct tattgttttg ttccatgtga
     6301 ttcttgtttc cctatgctct ttaatggaga atctgttgtc gaaaggaaga tggccagaaa
     6361 taagaacttc aggaccacgt ggctttgcat atacagagct taacaagctt tgagaaactc
     6421 ataaggttca agtcaccttc aaaagaaagg tacaatggaa acactcatag actgacacca
     6481 ttatcattaa ctaagaataa taaatttgct cctatcctgg gtcacgtgcc acggtaagat
     6541 gtatagtatg gccatccaca ctaattgtag gaggacagct aaatggacag tcagtcactt
     6601 tgaggtcact gcatttgact ggaaatgtat aatgtgtttt actgttgaaa aaaatatgag
     6661 ctctgtttca actaacgtgt catcttgtat ttctttcaag gaaaccaatt agattcaaat
     6721 gtaggatatt acaggttggt tgaaatccca tgtacaaata aaattctatg tctgaaagat
     6781 tcttctgttt gaacttaaga agaataaact acactttact ttatgtgcag aaatgagaca
     6841 ttctgacaat aatgaagtgc ttcatggtat ctcaacagtg tactttcttg taatattttc
     6901 catcttttta acctgagcat gtttgttttg tctgctttct atacagagct cagatttgtc
     6961 taatgattta aatgtaaccc aagactttaa gtgtgggtta cttaatgtgt tcctgaagag
     7021 gttgtgcttc ctgacaaatg ctgtcaggtc attatttgct gtatcaaagt tccagtggct
     7081 tcagaaatca tagcatccca tggttttgtg gtatctgggt ttgtgtaatg ttgttgacac
     7141 ctgtatttaa tgacacctgc acacctttca aataaaaaca tgtttttctt caagtaaaaa
     7201 aaaaaaaaaa aa
//
