LOCUS       NM_175543               3145 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RAB11 family interacting protein 4 (class II)
            (Rab11fip4), mRNA.
ACCESSION   NM_175543
VERSION     NM_175543.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3145)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3145)
  AUTHORS   Hara,Y., Fukaya,M., Sugawara,T. and Sakagami,H.
  TITLE     FIP4/Arfophilin-2 plays overlapping but distinct roles from
            FIP3/Arfophilin-1 in neuronal migration during cortical layer
            formation
  JOURNAL   Eur J Neurosci 48 (9), 3082-3096 (2018)
   PUBMED   30295969
  REMARK    GeneRIF: FIP4 and FIP3 play overlapping but distinct roles in
            neuronal migration downstream of Rab11 and Arfophilin-1 during
            cortical layer formation.
REFERENCE   3  (bases 1 to 3145)
  AUTHORS   Wang,J.Z., Yang,S.X., Ye,F., Xia,X.P., Shao,X.X., Xia,S.L.,
            Zheng,B. and Xu,C.L.
  TITLE     Hypoxia-induced Rab11-family interacting protein 4 expression
            promotes migration and invasion of colon cancer and correlates with
            poor prognosis
  JOURNAL   Mol Med Rep 17 (3), 3797-3806 (2018)
   PUBMED   29257314
  REMARK    GeneRIF: Rab11-FIP4 expression promotes migration and invasion of
            colon cancer cells and correlates with poor prognosis.
REFERENCE   4  (bases 1 to 3145)
  AUTHORS   Hara,Y., Fukaya,M., Hayashi,K., Kawauchi,T., Nakajima,K. and
            Sakagami,H.
  TITLE     ADP Ribosylation Factor 6 Regulates Neuronal Migration in the
            Developing Cerebral Cortex through FIP3/Arfophilin-1-dependent
            Endosomal Trafficking of N-cadherin
  JOURNAL   eNeuro 3 (4) (2016)
   PUBMED   27622210
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3145)
  AUTHORS   Muto,A., Aoki,Y. and Watanabe,S.
  TITLE     Mouse Rab11-FIP4 regulates proliferation and differentiation of
            retinal progenitors in a Rab11-independent manner
  JOURNAL   Dev Dyn 236 (1), 214-225 (2007)
   PUBMED   17089410
  REMARK    GeneRIF: identification of Rab11-family interacting protein 4
            (Rab11-FIP4) as a gene strongly expressed in the developing mouse
            retina.
REFERENCE   6  (bases 1 to 3145)
  AUTHORS   Venturin,M., Bentivegna,A., Moroni,R., Larizza,L. and Riva,P.
  TITLE     Evidence by expression analysis of candidate genes for congenital
            heart defects in the NF1 microdeletion interval
  JOURNAL   Ann Hum Genet 69 (Pt 5), 508-516 (2005)
   PUBMED   16138909
REFERENCE   7  (bases 1 to 3145)
  AUTHORS   Jenne,D.E., Tinschert,S., Dorschner,M.O., Hameister,H., Stephens,K.
            and Kehrer-Sawatzki,H.
  TITLE     Complete physical map and gene content of the human NF1 tumor
            suppressor region in human and mouse
  JOURNAL   Genes Chromosomes Cancer 37 (2), 111-120 (2003)
   PUBMED   12696059
REFERENCE   8  (bases 1 to 3145)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK046734.1.
            
            On Apr 6, 2007 this sequence version replaced NM_175543.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK046734.1, AK147219.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3145              AK046734.1         3-3147
FEATURES             Location/Qualifiers
     source          1..3145
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.88 cM"
     gene            1..3145
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /note="RAB11 family interacting protein 4 (class II)"
                     /db_xref="GeneID:268451"
                     /db_xref="MGI:MGI:2442920"
     exon            1..223
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..1972
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /note="FIP4-Rab11; mRab11-FIP4A"
                     /codon_start=1
                     /product="rab11 family-interacting protein 4"
                     /protein_id="NP_780752.1"
                     /db_xref="CCDS:CCDS25123.1"
                     /db_xref="GeneID:268451"
                     /db_xref="MGI:MGI:2442920"
                     /translation="MAGGAGWAGAPAALLRSVRRLREVFEVCGRDPDGFLRVERVAAL
                     GLRFGQGEEVEKLVKCLDPNDLGRINFKDFCRGVFAMKGCEELLKDVLSVESAGTLPC
                     SPDIPDCVEQGSDFSGSTDGEQLPREPDFFQEDEEEAMTLALPEGPQELDMDSPMESS
                     QGPEGSVKGCGEEKEPELGGLFLPEDKCLVLTPSVTTSDLSTHSTASLISNEEQFEDY
                     GEGDDVDCAPSSPCPDDETRTNVYSDLGSSVSSSAGQTPRKMRHAYNSELLDVYCSQC
                     CKKINLLNDLEARLKNLKANSPNRKISSTAFGRQLMHNSNFSSSNGSTEDLFRDSIDS
                     CDNDITEKVSFLEKKVTELENDSLTSGGLKSKLKQENMQLVHRVHELEEMVKDQETTA
                     EQALEEEARRHREVYCKLEREKSTELELLNTRVQQLEEENTDLRTTVARLKSQTEKLD
                     EERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLEFQKEREATQELIEDLRRELEH
                     LQMYKLDCERPGRGRSSSGLGEFNARAREVELEHEVKRLKQENHKLRDQNDDLNGQIL
                     SLSLYEAKNLFATQTKAQSLAAEIDTASRDELMEALKEQEEINFRLRQYMDKIILAIL
                     DHNPSILEIKH"
     exon            224..311
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            312..400
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            401..624
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            625..819
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            820..954
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            955..990
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1090
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1194
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..1335
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1336..1417
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1418..1555
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1711
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1712..1855
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..3145
                     /gene="Rab11fip4"
                     /gene_synonym="A730072L08Rik; mKIAA1821; RAB11-FIP4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcggtgcg agcgcgatgg cgaaggcggc agcgcggggc ttgggctagc tgccggcggc
       61 gcggatggcg ggtggcgcgg gctgggcggg cgcccccgcg gctctgctgc gctccgtgcg
      121 ccgcctgcgc gaagtgttcg aggtgtgcgg ccgcgacccc gacggctttc tacgcgtgga
      181 gcgcgtcgcg gcgctcggcc tgcgcttcgg gcaaggagag gaggtggaaa aacttgtgaa
      241 gtgtttggat cccaatgacc tggggagaat caacttcaag gatttttgcc gcggagtatt
      301 cgccatgaaa gggtgtgagg agctgctgaa ggacgtgctg tcggtggaga gcgcagggac
      361 cctgccatgt tctccagaca tcccagactg tgtggagcag ggcagcgact tctctggctc
      421 tactgatggc gagcaactcc ccagggaacc cgacttcttc caggaagacg aagaggaagc
      481 gatgacattg gccctacctg agggacccca ggagttagac atggacagtc ccatggagag
      541 cagccaaggc ccggagggct ctgtcaaggg ttgtggcgag gagaaggagc ctgagctggg
      601 gggcctgttc ctgccagagg acaagtgcct cgtcctcact ccatctgtga ccacatcaga
      661 cctttccact cactccaccg cctctcttat cagcaacgag gagcaatttg aagactatgg
      721 cgagggggat gacgtggact gtgctcccag cagcccatgc cccgacgatg agaccagaac
      781 caatgtctac tcagatctgg gatcttcagt gtcttccagt gcgggacaga ccccaaggaa
      841 gatgcgacat gcctacaaca gcgagctgct ggacgtgtac tgctctcagt gctgcaagaa
      901 gatcaacctg ctgaatgacc tggaggcccg gctgaagaac ctgaaggcca acagccccaa
      961 ccggaagatc tcaagcacag cctttggacg gcagctcatg cacaacagta acttcagcag
     1021 cagtaatggc agcaccgagg acctgttccg tgacagcatc gactcctgtg acaatgacat
     1081 cacagagaag gtgagcttcc tggaaaaaaa ggtaacagaa ctggagaacg acagcctgac
     1141 gagcgggggc ctgaagagca agctgaagca agagaacatg cagctggtgc acagggtgca
     1201 cgagctggag gagatggtga aggatcagga gaccacagcg gagcaggcgc tggaggagga
     1261 ggcccggcga caccgtgagg tctactgcaa gctggagcgg gaaaagagca cagagctgga
     1321 gctgctcaac accagggtgc agcagttgga ggaagagaac acagatctga gaacgacagt
     1381 ggctcgactc aagtcacaga ccgagaagct ggacgaggag cggcagcgca tgtctgaccg
     1441 gctggaggac accagcctgc gactgaagga cgagatggac ctttacaagc gcatgatgga
     1501 caagctgcgg cagaaccgcc tggagttcca gaaggagcgg gaggcgacgc aggagctcat
     1561 cgaggacttg cggagagagc tggagcacct gcagatgtac aagctggact gcgagcggcc
     1621 aggtaggggc cgcagctcct ctggccttgg cgagttcaac gccagagccc gggaggtgga
     1681 acttgaacat gaggtcaagc gtctgaagca ggagaatcac aagctgcggg atcagaatga
     1741 tgatttaaat gggcagatcc tgagcctcag cctctacgag gcgaagaacc tctttgcaac
     1801 ccagaccaaa gcccagtctc tggctgcaga aatcgacaca gcatctcgag atgagctaat
     1861 ggaggccctg aaggagcagg aggagatcaa cttccgactg agacagtaca tggacaagat
     1921 tatcctggct atactggacc acaacccctc catcttggag attaaacact gagtcagggt
     1981 tggctgcaga gcggccgtcg gacctgggac ctaagggcag gcctgcctga ggacgaagaa
     2041 agatgcaggc tttgcccaca tgcactctgt gattgtacct ctgagcaccc tctctgtgtg
     2101 tgctggtgtc cgtgcaagga gtgagcttgg ggccatggct gtgggtgaca acccacggtg
     2161 agctgtgtgt gcactttgta gcccctttgt gaggggcaga gggggctgga tgtgggggag
     2221 acactctcag gagttaacag caaggcctgg aagcttgcat ttaggatact gatgaaatga
     2281 ttctacctct gggataaggg ttagaagata ctctcaggag atgggttctc tcccctcccc
     2341 cactgaagtg gggacaaaac tgttacattc tccagaattt ggtgtccttg ccaacctttc
     2401 aggccacctt tcaagccggg tttttttgtt ttgttttctt tagctcagag gaggaagggg
     2461 tattggagag gcccctgagg tctagccccc tggggtgcag ataagcaggt ccagtggact
     2521 cggacttaca gagcagttag agtgcactgt ccatgccttt gggctaagtc catcgtagtt
     2581 ttctgagccc ctcccagtct tgcttgccta cctccccttt ctggtttggc tttgctttgt
     2641 tttgaagatg gaaaatacaa gcagcattca gctgggggtg gaaggaaggc caagaagggt
     2701 agggtgcccc aaggcaggtg tgtgttagca ctgggggcca aaaggagtga ttgcctggga
     2761 gagaggtgtg ttttcatggc tgcatcgtca cacatgacct ctctgggttc catgctcctt
     2821 ggtgaggaca ggcctaggga agggtttgca ggactgatac ccttgcctcg gctttcagac
     2881 ccatctgaat caggtcccca gttagagagc cgacacggct ggcaggaggt ccagtggaga
     2941 atactggggg aaccttagtc ttcggttccg tcaatacatg atgggaattc acatacacac
     3001 acccgtgttg ggggttgagg gagggttaaa atgtgatctg ggagtaggta ctgtatagaa
     3061 cattccggtt tatctcagtt ttatacagct tgtgattggt tggcttcctt accccagctc
     3121 ctataaaggt gtatggttca agttt
//
