LOCUS       NM_008997               6065 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RAB11B, member RAS oncogene family (Rab11b), mRNA.
ACCESSION   NM_008997
VERSION     NM_008997.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6065)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6065)
  AUTHORS   Joseph,I., Flores,J., Farrell,V., Davis,J., Bianchi-Smak,J.,
            Feng,Q., Goswami,S., Lin,X., Wei,Z., Tong,K., Feng,Z., Verzi,M.P.,
            Bonder,E.M., Goldenring,J.R. and Gao,N.
  TITLE     RAB11A and RAB11B control mitotic spindle function in intestinal
            epithelial progenitor cells
  JOURNAL   EMBO Rep 24 (9), e56240 (2023)
   PUBMED   37424454
  REMARK    GeneRIF: RAB11A and RAB11B control mitotic spindle function in
            intestinal epithelial progenitor cells.
REFERENCE   3  (bases 1 to 6065)
  AUTHORS   Barlow,H.R., Ahuja,N., Bierschenk,T., Htike,Y., Fassetta,L.,
            Azizoglu,D.B., Flores,J., Gao,N., De la,O. S, Sneddon,J.B.,
            Marciano,D.K. and Cleaver,O.
  TITLE     Rab11 is essential to pancreas morphogenesis, lumen formation and
            endocrine mass
  JOURNAL   Dev Biol 499, 59-74 (2023)
   PUBMED   37172642
REFERENCE   4  (bases 1 to 6065)
  AUTHORS   Knapp,L., Sun,H., Wang,Y.M., Chen,B.J., Lin,X., Gao,N., Chen,P. and
            Ren,D.
  TITLE     Rab11a Is Essential for the Development and Integrity of the
            Stereocilia and Kinocilia in the Mammalian Organ of Corti
  JOURNAL   eNeuro 10 (6) (2023)
   PUBMED   37225424
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6065)
  AUTHORS   Ramachandran,J., Zhou,W., Bardenhagen,A.E., Nasr,T., Yates,E.R.,
            Zorn,A.M., Ji,H. and Vokes,S.A.
  TITLE     Hedgehog regulation of epithelial cell state and morphogenesis in
            the larynx
  JOURNAL   Elife 11, e77055 (2022)
   PUBMED   36398878
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6065)
  AUTHORS   Schlierf,B., Fey,G.H., Hauber,J., Hocke,G.M. and Rosorius,O.
  TITLE     Rab11b is essential for recycling of transferrin to the plasma
            membrane
  JOURNAL   Exp Cell Res 259 (1), 257-265 (2000)
   PUBMED   10942597
REFERENCE   7  (bases 1 to 6065)
  AUTHORS   Bhartur,S.G., Calhoun,B.C., Woodrum,J., Kurkjian,J., Iyer,S.,
            Lai,F. and Goldenring,J.R.
  TITLE     Genomic structure of murine Rab11 family members
  JOURNAL   Biochem Biophys Res Commun 269 (2), 611-617 (2000)
   PUBMED   10708602
REFERENCE   8  (bases 1 to 6065)
  AUTHORS   Matsumoto,K., Asano,T. and Endo,T.
  TITLE     Novel small GTPase M-Ras participates in reorganization of actin
            cytoskeleton
  JOURNAL   Oncogene 15 (20), 2409-2417 (1997)
   PUBMED   9395237
REFERENCE   9  (bases 1 to 6065)
  AUTHORS   Lai,F., Stubbs,L., Lehrach,H., Huang,Y., Yeom,Y. and Artzt,K.
  TITLE     Genomic organization and expressed sequences of the mouse extended
            H-2K region
  JOURNAL   Genomics 23 (2), 338-343 (1994)
   PUBMED   7835882
REFERENCE   10 (bases 1 to 6065)
  AUTHORS   Lai,F., Stubbs,L. and Artzt,K.
  TITLE     Molecular analysis of mouse Rab11b: a new type of mammalian YPT/Rab
            protein
  JOURNAL   Genomics 22 (3), 610-616 (1994)
   PUBMED   8001972
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU705914.1, BY275360.1, AK146623.1, BM935109.1, AK043096.1 and
            AK036482.1.
            
            On Sep 15, 2006 this sequence version replaced NM_008997.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK146623.1, AK148022.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-133               BU705914.1         1-133
            134-189             BY275360.1         129-184
            190-2599            AK146623.1         2-2411
            2600-2634           BM935109.1         79-113
            2635-4189           AK043096.1         1-1555
            4190-6065           AK036482.1         1401-3276
FEATURES             Location/Qualifiers
     source          1..6065
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 17.98 cM"
     gene            1..6065
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /note="RAB11B, member RAS oncogene family"
                     /db_xref="GeneID:19326"
                     /db_xref="MGI:MGI:99425"
     exon            1..264
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             225..881
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /EC_number="3.6.5.2"
                     /note="RAS oncogene family protein"
                     /codon_start=1
                     /product="ras-related protein Rab-11B"
                     /protein_id="NP_033023.1"
                     /db_xref="CCDS:CCDS28628.1"
                     /db_xref="GeneID:19326"
                     /db_xref="MGI:MGI:99425"
                     /translation="MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTI
                     GVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENV
                     ERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTN
                     VEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVDISVPPTTDGQRPNKLQCCQSL
                     "
     exon            265..460
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            461..654
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            655..735
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            736..6065
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1917..1922
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /note="hexamer: ACTAAA"
     polyA_site      1952
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /note="major polyA site"
     regulatory      6040..6045
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6060
                     /gene="Rab11b"
                     /gene_synonym="A730055L17Rik"
ORIGIN      
        1 ccgcctttct ccgggagacc gagggctaga agggtggatc ccaggaggct cctacccccc
       61 gagctcggtt tctcagcctg attggcttgt ccaggtgcct gtcactaccg ctttcaccgt
      121 tgactggcct ttagaccgcc gctctacgcg gcgccggttc cgcccccgac gggtgtttgt
      181 ggtggggctg cggagtcgcc gatcccgccg gaagcgccag gacaatgggg acccgggacg
      241 acgagtacga ttacctattc aaagtggtgc ttattgggga ctcaggtgta ggtaagagca
      301 acctgctgtc acgcttcacc agaaacgaat tcaacctaga gagcaagagt accatcggag
      361 tggagttcgc cactcgcagc attcaggtgg acggcaagac catcaaggct cagatctggg
      421 acactgctgg ccaggagcgc taccgtgcca ttacctctgc gtactaccgt ggtgcagtgg
      481 gtgcactgct ggtatatgac attgccaagc acttgacata tgagaacgtg gagcgctggc
      541 tgaaggagct gcgggatcat gcagatagca acattgtcat catgctggtg ggcaacaaga
      601 gtgacctgcg ccaccttcgg gctgtgccca ctgatgaggc ccgtgccttt gcagaaaaga
      661 acaacttgtc cttcattgag acctcagcct tggattccac caatgtagag gaagcattca
      721 agaacatcct cacagaaatc taccgtattg tgtcacagaa gcaaatcgct gaccgtgcag
      781 cccacgatga gtcccctggc aacaacgtgg tggacatcag tgtgccaccc accaccgatg
      841 gacagagacc caacaagctg cagtgctgcc agagcctgtg actgccctgc actttctttt
      901 tcttttggtt ttggtttgtt ttgttttgtt tttcttggtt ttttttggtt tttcgagaca
      961 gggtttctct gtgtagccct ggcagtcctg ggactcactc tgtcaaccag gctggcctcg
     1021 aactcagaaa tccacctgcc tctgcctccc aagtgctggg attaaaggcg tgcgccacca
     1081 ctgcccggct tgccctgcac tttgacccag cgtgcgtgca cgtcctcgat ccttggccag
     1141 cccttcacca gtgtcctccc ggcccctccc ttgtccctct aggacaggct gctcccaccc
     1201 tccaagtgag ctccgcctgc cagcccaatg gcccaggaag agcaggagtc cagtggcctc
     1261 tcctgtcctg cctgctcaag agaagctaaa agccccttgc ttatgtacct gctcttggat
     1321 attgtgggca tcttgacagg atagggaggt tggtaggatg gacaaggcca gccagaggtg
     1381 aggaagatga gtggaaggaa cctgcttctc ctgttttcca gacttcagag atcgaaaccg
     1441 cctttcctct ctggccagtt gaccagctgg ccctgtatcc tcatcccaaa ctctctctga
     1501 gctgataccc gaagagccag gcatcagagg ctgagcaggt ggacattctg ggctctgcct
     1561 cctgcctaca ccaccatagc cagtgccagc acggcctcca gcattcccag gcctgcgcac
     1621 tcctgctcct gcctgtagat ttatgctggg agaagacacc cttgcccctc tccctcctcc
     1681 tctgcacgca gcgctctcct ctgcccatcc ccacttctct gtctcgtctc cgtgtctggt
     1741 caggaacctg tctgcaagtg aagcaatatc ttcgtgtttt gtatatacaa ctgctcttgt
     1801 agcctttggt ttttgttatt gtagagaaca gattctttat acactttgta aaatttacgc
     1861 caaaccccag ctctcgaact cttattctcc ctgtagccct tgcactgttg cccgttacta
     1921 aaatgtataa gccacttctg tacagaaacc taccactcag cttctgtctt ctttctctcc
     1981 accaaatgat gcacctgaac cagggccctt ttacgtgtcc ccaatagtag gttagcgtag
     2041 tacctgctga agacagtggg cagacatgct gatcttgcac agtaggctgt gagataagga
     2101 tcttgggctc caaggagggg agagtgagtc ctctgcaagt ggctcctgta gtatggagga
     2161 aggaaatgat ggtgacctga agtggcagcc ttcacttgga acagtttaag gagaagttgt
     2221 accagccttt cccaaatcgt ttgtatctag gattgacagg cctaggatgc cccctggtgt
     2281 gaatgggaag catgagcatg cttgccactt ccatctgctg ccaacaatgg actccttatc
     2341 tggagtcctg gcaaggaagg tgtgcttgat aacagtgggt gatgtcagct ctaccatggc
     2401 tgtctttact caagaatgac acttgatggg gacagtagag ggcaacagtg actacaaggt
     2461 gagcagctct tgatcttcac tggcgcttcc cagaacccat tgcccttgtt cctgtaccca
     2521 aagcagatag taagtaacga gatgtgttct tctccacccc tgaaggaaat cttacaatcc
     2581 aaatacagcc agctattcta gaaaccctca tctctaaatg aagagaacct gggggtgtcc
     2641 tgcctcctga ttctggaatg aatgtagcct ccttgtgtgt gttggaagag ggaagtggtc
     2701 aatcccagat acatctctca gatccaagct gggcacagtg gctcagactt gttacctcat
     2761 actttggagg tggtgacagg agatcaggag ttcaaggcca gcctcagcta cataagaccc
     2821 tgtctaagaa aataaaattt aaattaaaaa aaaaaaaaaa ggaaaaacta aagaccccaa
     2881 agaagttggg gtggatttta tgggcatctc acaatccaga agttaccctt ggccaaagct
     2941 atgatggaag gtggactgtc tagcagacat aagcaggagg tagcataggt ctaagactca
     3001 gctcgcagga actgccaatg gagttgacgt actggaagaa ccaactccaa gttgtcttct
     3061 gatttccaca tgacactaaa tatttttaca aaacaaatgt cactgggtgg gggcaaaggc
     3121 tctaggtaaa agtgctgcat gagtacagct cccagaactc acaaagttgg actcaatgta
     3181 aacacctgta atgtcaacaa tccttcgggg aaatgagagg cagagccagg gtattcagaa
     3241 gctcgtggac tagcttctgt agaggtaaaa caagaaagac cctgtctcaa accatgtgaa
     3301 agatgaggac tccctataaa gttgtcctcc cacctggacc cttaggagag actatttgca
     3361 cacacaaatg tgcacatagc cacatgcaat gtgcacacac aaatgtatcc acatagagta
     3421 tacactgatg ctctcacagt gtacacacgt aagtagatat gcaatgtcca tgcaacacat
     3481 tatatgcttt ggttgtaaga aatggaaaaa tcaaggagaa ctgatctgga agcttcctgc
     3541 ctagctttca tagtgccaga agctgtgtag cagctagagg agaactgtct ttgacagctc
     3601 tgcctgtaga ccctgctaca gtactaacat gttaggcaag atatgcctgc tggtgccata
     3661 gtggcatgac ttacgagtag cagttccttt ctgattaaat ctaaagccca ttccacagaa
     3721 gtgagttcac atttggtacc gtgagcctag tcaaaagctt gcagctaggg atgttgtagg
     3781 ctcttacagg atgcacatgc ctgcactcac ctatactagc attgtctttc acaacaaaaa
     3841 taaaattagt gcataagcaa ctcattttat tgtttggtca agcttttagc tgctgtgtcc
     3901 aggtagggac tagactagaa ctagaggcag aatatccagg gctaagtcta agccaaacaa
     3961 acttttatta tagaatcgtt gggtttgtaa ctgtcatagt gtagcaaggg actggagaaa
     4021 acactacaaa gaccaacaca tgaaagacaa aaacacaaaa ctactgaaaa cccttcccca
     4081 catgcaacaa acggaacctg ctcaagaaag cccgtgaact tgggaggcag gagtatccct
     4141 tagtttgagg ccagtctggt ctacatagca aattccagga ctatacagga aaaagagaaa
     4201 gcccaagata taaaaatgtg gggaagcagg tacaatgcta atgcacctct aatgaatcat
     4261 gaaccttgtg gcttagcatg tctgagtaca tattttcccc tcagctcaca gagctcttgc
     4321 tgtccaggcc ttgatttgta atccagggtg gccctgaact caagagatct acctgcctct
     4381 acctcctgaa tgctgggatt aaaggcatgt accactatgc ccagcttgct ttttctttct
     4441 ttttgaaaca ttatgtgtat gcatgttttg actgcatgta tgtctgtata ccacatgcat
     4501 gcagtttcca cagaggtcag atgaacatgt caactggagt tacaaatagt tgtaaactgc
     4561 catgtgagtg ctgggaattg aacctgagtc ctctagtaga gcaacctgtg ctattaatca
     4621 caaagccatt tccatctttc cttttcttta taaactttct ctttttgtct ctttatatat
     4681 gtatatgttg agtttgtcat gtctgcatgg tgtatgttca tatgtgtgta gagatgcgca
     4741 tatacctatg gagagtacca gaggtaagtt agaaagtgtc ttcctctatt tgaggtagga
     4801 tttctcccag caagcccaag caatcccctt ctccctgcat catcagtgct gggatcacag
     4861 atgtgtgcag ggtgacactt ggtttattac atggatgatg gcactcaagg tctggtcttc
     4921 ttgcttacac agcaagtgct cttagccact aagccaccat tcagccctag actctatttc
     4981 taaccatatg tcctagtgca attctctgtc ctggaacagt agaccctgga aacctcagtg
     5041 ggtggcctcg aaactctgat ccgaacctga aacaatatgt tagtggtgtt gggaagtgtg
     5101 acctttctga gttaactaga aacagatgag gtcatcagag tagggctccc atgacagcat
     5161 tgcagcttca taagatgagg aagagagacc cagctcggca cacttagcgt ctcaccttgc
     5221 aattccttct gccacgttac aaagttgtaa gaagttcttc accagatgtt gcaccttgct
     5281 cctagacctc tcagtcatca gaatagtgaa ttaaataagc atctatactt taaaaaatta
     5341 tattctatgt ctgcctgcct gcctgtctgt ctgtctatct gagcttagtg gacaatttat
     5401 tttctggaat tgattcttct tcactgtgtg ggttccaggg atcaaactga agttgtgagg
     5461 cttggtggtg ggcaccctta cctgccgaat tatccaactg accctcctct ttccaatatc
     5521 ctgctcccaa accctttgtc acggcaacta aaatgatctt agacaggcga tgtggctaga
     5581 agtttgattg gatgtgagtt ggaaggggct gttgggaaga tgaataacta ttctggacca
     5641 agggagccgg agcagtcaga gaatgaagag tctgggataa ttttggtact tggttagtat
     5701 tagaagatta ttttggctgg cttaatgtca acttgaccca agctagacac atctgaaaga
     5761 agagactatc agttgaaaaa aaaatgcctg cataagttcc agctataaag cattttctga
     5821 attagtgatt gatggggcta gagggcccgg tccattgtag gttgtgtctc ccctgggttg
     5881 gtggttctgg gttctgtaag aaaggctaag caagccatga agagcaagct gataagcagc
     5941 actcatcttc tgcattggct tcagcctcca ggaccttacc ctgtttgagg tcctgtcttg
     6001 accttcttca gtgatggatt acagtatgaa gtgtgagcca ataaaccctt tccttctcaa
     6061 cttgc
//
