LOCUS       NM_017382               2333 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus RAB11A, member RAS oncogene family (Rab11a), mRNA.
ACCESSION   NM_017382
VERSION     NM_017382.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2333)
  AUTHORS   Janusz-Kaminska,A., Brzozowska,A., Tempes,A., Urbanska,M.,
            Blazejczyk,M., Milek,J., Kuzniewska,B., Zeng,J., Weslawski,J.,
            Kisielewska,K., Bassell,G.J. and Jaworski,J.
  TITLE     Rab11 regulates autophagy at dendritic spines in an mTOR- and
            NMDA-dependent manner
  JOURNAL   Mol Biol Cell 35 (3), ar43 (2024)
   PUBMED   38294869
  REMARK    GeneRIF: Rab11 regulates autophagy at dendritic spines in an mTOR-
            and NMDA-dependent manner.
REFERENCE   2  (bases 1 to 2333)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2333)
  AUTHORS   Gu,J.X., Wang,J., Ma,F.J., Liu,M.M., Chen,S.H., Wei,Y., Xiao,Y.F.,
            Lv,P.Y., Liu,X., Qu,J.Q., Yan,X.X. and Chen,T.
  TITLE     Rab11a in the spinal cord: an essential contributor to complete
            Freund's adjuvant-induced inflammatory pain in mice
  JOURNAL   Mol Brain 16 (1), 70 (2023)
   PUBMED   37770900
  REMARK    GeneRIF: Rab11a in the spinal cord: an essential contributor to
            complete Freund's adjuvant-induced inflammatory pain in mice.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2333)
  AUTHORS   Wang,B., Liang,Z., Tan,T., Zhang,M., Jiang,Y., Shang,Y., Gao,X.,
            Song,S., Wang,R., Chen,H., Liu,J., Li,J., Ren,Y. and Liu,P.
  TITLE     CRB3 navigates Rab11 trafficking vesicles to promote gammaTuRC
            assembly during ciliogenesis
  JOURNAL   Elife 12, 86689 (2023)
   PUBMED   37737843
  REMARK    GeneRIF: CRB3 navigates Rab11 trafficking vesicles to promote
            gammaTuRC assembly during ciliogenesis.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2333)
  AUTHORS   Joseph,I., Flores,J., Farrell,V., Davis,J., Bianchi-Smak,J.,
            Feng,Q., Goswami,S., Lin,X., Wei,Z., Tong,K., Feng,Z., Verzi,M.P.,
            Bonder,E.M., Goldenring,J.R. and Gao,N.
  TITLE     RAB11A and RAB11B control mitotic spindle function in intestinal
            epithelial progenitor cells
  JOURNAL   EMBO Rep 24 (9), e56240 (2023)
   PUBMED   37424454
  REMARK    GeneRIF: RAB11A and RAB11B control mitotic spindle function in
            intestinal epithelial progenitor cells.
REFERENCE   6  (bases 1 to 2333)
  AUTHORS   Fukuda,M.
  TITLE     Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and
            Noc2. Identification of a critical determinant of Rab3A/Rab27A
            recognition by Rim2
  JOURNAL   J Biol Chem 278 (17), 15373-15380 (2003)
   PUBMED   12578829
REFERENCE   7  (bases 1 to 2333)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 2333)
  AUTHORS   Fukuda,M., Kuroda,T.S. and Mikoshiba,K.
  TITLE     Slac2-a/melanophilin, the missing link between Rab27 and myosin Va:
            implications of a tripartite protein complex for melanosome
            transport
  JOURNAL   J Biol Chem 277 (14), 12432-12436 (2002)
   PUBMED   11856727
REFERENCE   9  (bases 1 to 2333)
  AUTHORS   Kuroda,T.S., Fukuda,M., Ariga,H. and Mikoshiba,K.
  TITLE     The Slp homology domain of synaptotagmin-like proteins 1-4 and
            Slac2 functions as a novel Rab27A binding domain
  JOURNAL   J Biol Chem 277 (11), 9212-9218 (2002)
   PUBMED   11773082
REFERENCE   10 (bases 1 to 2333)
  AUTHORS   Bhartur,S.G., Calhoun,B.C., Woodrum,J., Kurkjian,J., Iyer,S.,
            Lai,F. and Goldenring,J.R.
  TITLE     Genomic structure of murine Rab11 family members
  JOURNAL   Biochem Biophys Res Commun 269 (2), 611-617 (2000)
   PUBMED   10708602
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147122.1, AC147560.3 and AK031143.1.
            
            On Sep 18, 2009 this sequence version replaced NM_017382.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147122.1, AK014268.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-938               AK147122.1         2-939
            939-939             AC147560.3         124871-124871       c
            940-2229            AK031143.1         843-2132
            2230-2333           AK147122.1         2230-2333
FEATURES             Location/Qualifiers
     source          1..2333
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 34.87 cM"
     gene            1..2333
                     /gene="Rab11a"
                     /note="RAB11A, member RAS oncogene family"
                     /db_xref="GeneID:53869"
                     /db_xref="MGI:MGI:1858202"
     exon            1..173
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..784
                     /gene="Rab11a"
                     /EC_number="3.6.5.2"
                     /note="rab-11"
                     /codon_start=1
                     /product="ras-related protein Rab-11A"
                     /protein_id="NP_059078.2"
                     /db_xref="CCDS:CCDS23282.1"
                     /db_xref="GeneID:53869"
                     /db_xref="MGI:MGI:1858202"
                     /translation="MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTI
                     GVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENV
                     ERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTN
                     VEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKVQCCQNI"
     exon            174..369
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
     exon            370..563
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
     exon            564..644
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
     exon            645..2333
                     /gene="Rab11a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      840..845
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab11a"
                     /note="hexamer: AATATA"
     polyA_site      864
                     /gene="Rab11a"
                     /note="major polyA site"
     regulatory      1004..1009
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab11a"
                     /note="hexamer: AATAAA"
     polyA_site      1029
                     /gene="Rab11a"
                     /note="major polyA site"
     regulatory      2309..2314
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Rab11a"
                     /note="hexamer: AATAAA"
     polyA_site      2327
                     /gene="Rab11a"
ORIGIN      
        1 atacagggcg gggctcgtca ccgggtccgg cagctgaagc tcctcgctcg ctcgggttac
       61 ccctgcagcg acgccccctg gtcccgccgc cgttgccacc gccgctcccg cccctcagct
      121 cctcggccgc gccatgggca cccgcgacga cgagtacgac tacctcttta aagttgtcct
      181 tattggagat tctggtgttg gaaagagtaa cctcctgtct cgatttactc gaaatgagtt
      241 taatctggaa agcaagagta ccattggagt agagtttgca acaagaagca tccaggttga
      301 tgggaaaaca ataaaggcac agatatggga cacagcaggg caggagcggt acagggctat
      361 aacgtctgca tactatcgtg gagcagtagg tgccttattg gtttatgaca ttgctaagca
      421 tctcacatat gaaaatgtag agcgatggct gaaagaactg agagatcatg ctgatagtaa
      481 cattgttatc atgcttgtgg gcaataagag tgatttacgt catctcaggg cagttcctac
      541 agatgaagca agagcttttg cagagaagaa tggtttgtca ttcattgaga catctgctct
      601 agattctaca aatgttgaag ctgcttttca gacaattcta acagagatat accgcattgt
      661 ttctcagaag caaatgtcag acagacgtga aaatgacatg tctccaagca acaatgtggt
      721 tcctattcat gttccgccca ccactgagaa caagccaaag gtgcagtgct gtcagaacat
      781 ctaaggcgtc tcttccccta gaaggctgtg tatagtccat ttcccaggtc tgagatttaa
      841 atatatttgt aattcttgtg gtcactttct gtgttttatt acttccttac acttaagaat
      901 cttcccatgt cttaagtctt ttgatttggc tttataaaat cctcaacttt gtcctgaatg
      961 actgcagttc tttttcatgc tatggcttct ctagccttag tttaataaac tgaatgtttg
     1021 aagttctcag ttattgttta ctcttcatca tggaagcctg tcactgtagg acagaataga
     1081 actctatcac ttgaagttta gacctattgg tcctgatcag atctaagaca accttagaaa
     1141 taagctattg ttttgccaca gagcagcttg taagacactc ttctcaatac agtacatatt
     1201 ttgacagatc taaggattgc cctgtaaaca taacagcatt ttgagagctt gaagattttc
     1261 cattgtggaa gtcagtttct aaaatgcctt aataggtcta tgttgtaaat tttttcttta
     1321 atttttgtaa gcatcaaaca tgatggggat tcttttttgt tgtttttctg gaaaagaatt
     1381 aataaacaca aaggactgtt atggtttgca tagggtgtgg ttatgtggtc aaagttaccc
     1441 tgctgtctgg taggctagtg gacttctgtc tgaggtgtct ctgttgcagt gatcggcagc
     1501 cagagtagct taaccaatct catttcctag attgtgatat ttttattgct catgtaataa
     1561 ctagcttaat gctggtaata tcacattttg aagtgttaat tttgctttta aacctgtcta
     1621 gtaagtgaaa tgcagcctaa ttttatcacc atattcagca accagcatgg gtaattattt
     1681 taacaatgct tatatttgag ttctgcagtg tataatggaa tatagctcaa ttaatccttt
     1741 ggttttagta tgtctaaaga atacagtgag aagttaattt atactcaagt ggtaccactt
     1801 aaaggcatgt gttcttttag tatgtaaagt gaaatagtac cttgaattta agtagaatgt
     1861 acttagccat tgtagggccc tgaaatagat ttttccacta cataattgaa atcaatggaa
     1921 caactagttt ctcattcaga aatgtacaca ctaatactta gttttacttc cttgtggata
     1981 atattaagca cttaccctga cgttttctga aagttaactg caaagacgtt attaaggatg
     2041 gtgggatacc tgcaaaaact gtgtgggctt gcatagatga ctatgtttca tggttaaatc
     2101 ttctgccttt tgcagtgctc atgatgtgtg gggagcacag aaggcattgc tatagtcagt
     2161 cattttgttt ttcttttgta gttatttgtt attttagtgt attggttata aagatactgt
     2221 ctatttataa attgctactt tgtattttat gcatgctctg tatttggact tttttttaat
     2281 ctattgattt ggagtacatc ctcatcctaa taaacagtta caggggcttt ccc
//
