LOCUS       NM_177464               3979 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus R3H domain and coiled-coil containing 1 like
            (R3hcc1l), mRNA.
ACCESSION   NM_177464
VERSION     NM_177464.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3979)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3979)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 3979)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124552.3.
            
            On May 2, 2007 this sequence version replaced NM_177464.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK082926.1, AK147893.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                AC124552.3         169631-169683       c
            54-1843             AC124552.3         124147-125936       c
            1844-2019           AC124552.3         112287-112462       c
            2020-2090           AC124552.3         106498-106568       c
            2091-2186           AC124552.3         105568-105663       c
            2187-2327           AC124552.3         104945-105085       c
            2328-3979           AC124552.3         96232-97883         c
FEATURES             Location/Qualifiers
     source          1..3979
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 36.47 cM"
     gene            1..3979
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /note="R3H domain and coiled-coil containing 1 like"
                     /db_xref="GeneID:52013"
                     /db_xref="MGI:MGI:1196316"
     exon            1..53
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /inference="alignment:Splign:2.1.0"
     exon            54..1843
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..2395
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /note="growth inhibition and differentiation-related
                     protein 88 homolog; growth inhibition and differentiation
                     related protein 86"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein R3HCC1L"
                     /protein_id="NP_803415.1"
                     /db_xref="CCDS:CCDS29829.1"
                     /db_xref="GeneID:52013"
                     /db_xref="MGI:MGI:1196316"
                     /translation="MQQEAERCRVRTKRPDMALYVPKARRGTALLKSSDQEEGHGPPA
                     FVPKDQKEGCLPQKISASKPESQRRGAGHSDRKDVDCREGKRSASQLRKDRCPQKQNK
                     EKACSKKGAEESTEASSQEHQHRAPDAGIVSSIPLQRLFKPKDMDCWEVQTAGATGHW
                     RVSPSQSSSEVSAAQVPSRPFQNVELCDFSGETFVNRNLESSIVTEAKVPELVSQFPQ
                     VVTTLLKPDGMAMPVTLSSDSETAPSSLETPDGMSKHSPGDISVVSVPGGPDEDVDST
                     FVDFEVESEGTVNSTESVLGQKGVDSILETVDNVSLKMAVVSKLESTNGTIDPAVTRE
                     CESDSSADELCVKSEPSDTAVLVHEIDTDDGFRNVCDSTSKACMVDIAGTACDPVTEG
                     SSCTGAVGESGESSGNMRNFSDYIEMSADVAPLDRAKSENDSENISSLSACSDIYAES
                     IASGFTESTGKLIESVSDGASSLPIKKTADSNIATCLDSELSMSDASDVLLESALGSD
                     LDTTEEMTEALHDLKTAEEFKTKEEDYSESVVCGISFSDSSVETSVDLKTTDTSHIQG
                     SSAVEESWESMFNDDGDCVDPRLLLELSGNVKNRKSIQEPRFDYYSHELPDIDLSECE
                     FPHVIEIYDFPQEFRTEDLLRIFCSYQKKGFDIKWVDDTHALGVFASPITARDALGTK
                     HTMVKIRPLSQATRAAKAKARACAEFLQPAKERPETSAALARRLVISALGVRSKQSKT
                     EREAELRKLQEARERKRLEAKQREDIWEGRDQSVV"
     exon            1844..2019
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2090
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /inference="alignment:Splign:2.1.0"
     exon            2091..2186
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /inference="alignment:Splign:2.1.0"
     exon            2187..2327
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /inference="alignment:Splign:2.1.0"
     exon            2328..3979
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3069..3074
                     /regulatory_class="polyA_signal_sequence"
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /note="hexamer: ATTAAA"
     polyA_site      3093
                     /gene="R3hcc1l"
                     /gene_synonym="1700036B12Rik; C10orf28; D19Ertd386e;
                     GIDRP86; Gidrp88"
                     /note="major polyA site"
ORIGIN      
        1 ggaagagcag gcgcttcatg gtggcagcgg aagcggagag cgacagcgtc ccgattgaag
       61 tggtgccatg cagcaagaag cagagagatg tagagttcga accaaaaggc ctgacatggc
      121 actctatgta cctaaagctc gaaggggaac agctctcctc aagtcaagtg accaggagga
      181 aggccatggg cctcctgcct ttgtgccaaa agatcaaaaa gaaggttgtc ttccccagaa
      241 gatctctgca agtaaacccg agtcccagag acgaggtgca ggccattctg ataggaagga
      301 tgttgactgt agggaaggaa agagatctgc atcacaacta aggaaagaca ggtgcccaca
      361 aaaacagaat aaagagaagg cttgttctaa gaaaggagct gaagaatcca cagaagcctc
      421 atcccaagaa catcaacaca gagctcccga cgctgggatt gtatctagta tacctttaca
      481 aagacttttt aaaccaaagg acatggactg ttgggaagtt cagactgcgg gagcgacagg
      541 acactggcgg gtgtctccat ctcagtcttc ctcagaagtc agtgctgctc aggttccaag
      601 cagaccattc cagaatgtgg aactctgtga tttcagtggg gaaacttttg taaatagaaa
      661 tttggaaagc agcattgtaa ctgaggccaa agttccagag ctagtctccc aatttcctca
      721 agttgttacc actctgctga aaccagatgg tatggctatg ccagtaacac taagttctga
      781 ttctgaaact gcaccatcca gtctggaaac accagatggg atgtcaaagc acagtcctgg
      841 ggacatctct gtggtttctg ttcctggagg tccagatgaa gatgttgatt caacttttgt
      901 agactttgaa gttgagagtg agggtacagt caacagtaca gagtctgtct tgggtcaaaa
      961 aggtgtagat tccattcttg agactgtgga taacgtttct cttaaaatgg cggtagtcag
     1021 caaattagag agcacaaatg gcactattga tccagcagtg actagagaat gtgagagtga
     1081 cagctctgct gatgagttat gtgtaaagtc tgaaccttct gatacagcgg tcctcgtgca
     1141 tgaaatagac acagatgatg gatttaggaa tgtatgtgac agtaccagca aggcttgtat
     1201 ggtggacatt gcaggtacag cttgtgaccc tgtaactgaa ggcagctctt gtacaggtgc
     1261 agttggagaa tctggtgaga gtagtggcaa catgagaaat ttctcagatt atatagaaat
     1321 gagtgcagat gtagctccac ttgatagagc taagagtgag aacgactctg aaaacattag
     1381 cagcctaagt gcttgctcag atatttatgc tgagagtatt gcatctggtt ttacagagtc
     1441 aacaggaaag ttgatagaaa gtgtgtcaga tggtgcttcc tctttaccca taaagaagac
     1501 tgctgatagt aatattgcca cttgtctgga ctctgaactg agtatgtcag atgcatcaga
     1561 cgtacttttg gagagtgcct tgggcagtga tctggatacc actgaggaga tgacagaggc
     1621 cttgcacgac ctaaaaactg ctgaagagtt taaaacaaaa gaggaagatt actcagagag
     1681 tgtagtgtgt ggcatatcat tttctgattc atctgtggaa acatctgtag atctaaaaac
     1741 aacagacact tctcacatac aaggaagtag tgctgtggag gaaagctggg aatctatgtt
     1801 taatgatgat ggtgattgtg tagatccacg tcttctacta gagttatctg ggaatgtgaa
     1861 gaacagaaaa agcatccagg agcctagatt tgattattac agccatgaac ttcctgatat
     1921 tgacctcagt gaatgtgaat tcccacatgt cattgaaatt tatgattttc ctcaagaatt
     1981 tcgtacagaa gaccttttgc ggattttctg cagttaccaa aagaaaggat ttgatattaa
     2041 gtgggtagat gacacacatg ccttaggagt tttcgccagc ccaatcacag ctcgcgatgc
     2101 cctgggtact aaacatacca tggtgaagat ccggcccttg tcacaggcca caagagcagc
     2161 caaggccaaa gctagagcgt gtgctgagtt tctccagcca gcaaaggaac gacctgagac
     2221 ttcagcagcc ttagccagaa ggctagtcat cagtgccctt ggggttcgaa gcaaacagag
     2281 caaaactgaa cgggaagcag agctcaggaa actgcaggaa gcccgagaga gaaaacggtt
     2341 ggaagccaag caacgggaag acatctggga aggcagagac cagtctgtgg tttgaatatc
     2401 agttcctgaa aggaatgaat ccatgattgg gaagtggttg atattcttga gacaagagga
     2461 tctttccaga gctgtgcaca tgcagatgag catgttaaag aaaacatgaa caaaacagac
     2521 gacttggaga acgagggtcc agtcctcact cttgaattca gacctgtcca ctgtgacaga
     2581 gacgttaaaa ggaactgtca tgtgggaagg aaaatggaag tggcttctaa gcgtcctggg
     2641 tggagcaggt catcttcatg tgggtcaggc ctccaggaag tctgaagcaa atgtaaagca
     2701 aaacaggatt caagcctgca gtgataggag tcggaggtcc gtggcagggc agggcgctcc
     2761 ttagtacttc tcagagttga gaactgcagg atgaggggca gcagtaagac agggagagga
     2821 aacagctcac agacaggagt gcctggtgca ctcagcccgt acagagacta cactgctggc
     2881 ccagaactcc agagcccctg aaccgcagcg catcgtgggt gtttgttcct gagtgtgtac
     2941 taagcttggg gcctggtact tgggcctgca cagcagccgg gtctgctacc ttccttcctc
     3001 acaaggacca gccctaggga actgagtgcc gctccagttt aatcagtgat atcttgtgag
     3061 agggaaaaat taaaggctat tttataacat aaatcattat ggtgtttata aatcttaacc
     3121 cccatccaaa agccaacatc agaagaagaa aacagaaaaa cctgtaaatg agttctctag
     3181 tcttcaagtc tctgatggtg tgcctggttt agacaggtac taacttttat cagcccagtg
     3241 agtatagtgc tctctgtctt ctctgcccta gagtagatcc ctaagtgccg tcgtggcagt
     3301 tctgtgtggc agcttctctt gccctcgtct cctcatgcat cttccctcca acctcttgcg
     3361 ttgtttttcc atagccgtca aatctgacac cctgcaggaa acgtctggct cccagtgtgt
     3421 tcttggtacg atcttagcct gtgccagagg ggcttggcaa gcaggcccag accatgcagt
     3481 acagtgatgg gccgagccgc cggacagctt agagccacca gctcagcctt ttctgtctca
     3541 cagcggcctt cttggtggtt ttggaaagtc gttctgtgct gaggagacgg tagtgctggt
     3601 ctctaaggtg ctgaagtggc aggaaccggt gtcacattgt gttttcaact ggggcagaag
     3661 ttgcttttat tcccgtgaca atgatggatt attagctttg tctagaacgt ggtagaatgg
     3721 ggctcttcaa atatccctcg atgaccctgg ccttggctct gagtcctgac ctgcccctct
     3781 tgctagtccc ggctggagct ctgtcacagt tcttcagcat tgtttcttca ctccaggctt
     3841 gcctttccag aggctctgta cagtgccacc ttccatatgt gggaaagcat tgttttcttg
     3901 gtcctctgtt tctgctcaag tcttcagctg tgttcactct gctcgctctg ctctgtttga
     3961 gcagtgaata caatgaaag
//
