LOCUS       NM_175524               2953 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus pyroglutamylated RFamide peptide receptor like
            (Qrfprl), mRNA.
ACCESSION   NM_175524
VERSION     NM_175524.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2953)
  AUTHORS   Cook,C., Nunn,N., Worth,A.A., Bechtold,D.A., Suter,T.,
            Gackeheimer,S., Foltz,L., Emmerson,P.J., Statnick,M.A. and
            Luckman,S.M.
  TITLE     The hypothalamic RFamide, QRFP, increases feeding and locomotor
            activity: The role of Gpr103 and orexin receptors
  JOURNAL   PLoS One 17 (10), e0275604 (2022)
   PUBMED   36251705
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2953)
  AUTHORS   Takayasu,S., Sakurai,T., Iwasaki,S., Teranishi,H., Yamanaka,A.,
            Williams,S.C., Iguchi,H., Kawasawa,Y.I., Ikeda,Y., Sakakibara,I.,
            Ohno,K., Ioka,R.X., Murakami,S., Dohmae,N., Xie,J., Suda,T.,
            Motoike,T., Ohuchi,T., Yanagisawa,M. and Sakai,J.
  TITLE     A neuropeptide ligand of the G protein-coupled receptor GPR103
            regulates feeding, behavioral arousal, and blood pressure in mice
  JOURNAL   Proc Natl Acad Sci U S A 103 (19), 7438-7443 (2006)
   PUBMED   16648250
REFERENCE   3  (bases 1 to 2953)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB632079.1, AK051723.1 and AK048439.1.
            
            On Sep 25, 2008 this sequence version replaced NM_175524.3.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus to one that is more supported by available conservation
            data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK048439.1, BC119578.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                BB632079.1         190-256
            68-1442             AK051723.1         2-1376
            1443-2953           AK048439.1         1353-2863
FEATURES             Location/Qualifiers
     source          1..2953
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 30.19 cM"
     gene            1..2953
                     /gene="Qrfprl"
                     /gene_synonym="C130060K24Rik; Gpr103b"
                     /note="pyroglutamylated RFamide peptide receptor like"
                     /db_xref="GeneID:243407"
                     /db_xref="MGI:MGI:2441881"
     CDS             1..1251
                     /gene="Qrfprl"
                     /gene_synonym="C130060K24Rik; Gpr103b"
                     /codon_start=1
                     /product="uncharacterized protein LOC243407"
                     /protein_id="NP_780733.2"
                     /db_xref="CCDS:CCDS20206.2"
                     /db_xref="GeneID:243407"
                     /db_xref="MGI:MGI:2441881"
                     /translation="MSWNLTAEQLSALLRLHNLTRAQFIAHYGLRPLVLTPQLPARAR
                     LALLLVGMLIFALALFGNALVVYVVTRSKAMRTVTNIFICSLALSDLLIVFFCIPVTM
                     LQNVSDTWLGGAFICKMVPFVQCTAIVTEILTMTCIAVERHQGLVHPFKMKRQYTNQR
                     AFTMLGVVWLVAIIIGSPMWHVQRLEIKYDFLYEKEHICCLEEWSSPVHQKIYTTFIL
                     VTLFLLPLLLLSVLYGKIGYELWIKKRIGDGSVLRTIHGKEMFKIARKKKRAVIMMVT
                     VVVLFAVCWAPFHIVHMMIEYSNFEKEYDEVTIKMIFAIVQIIGFFNSICNPIIYALM
                     NENFKKNFVSAVCYCIVKETPSSARKHGSSGAMVMHRRAKLAARENPVEIKGEAFGGS
                     NIDIKWCEQPEKKKRRSKVASCPL"
     exon            1..337
                     /gene="Qrfprl"
                     /gene_synonym="C130060K24Rik; Gpr103b"
                     /inference="alignment:Splign:2.1.0"
     exon            338..496
                     /gene="Qrfprl"
                     /gene_synonym="C130060K24Rik; Gpr103b"
                     /inference="alignment:Splign:2.1.0"
     exon            497..558
                     /gene="Qrfprl"
                     /gene_synonym="C130060K24Rik; Gpr103b"
                     /inference="alignment:Splign:2.1.0"
     exon            559..794
                     /gene="Qrfprl"
                     /gene_synonym="C130060K24Rik; Gpr103b"
                     /inference="alignment:Splign:2.1.0"
     exon            795..892
                     /gene="Qrfprl"
                     /gene_synonym="C130060K24Rik; Gpr103b"
                     /inference="alignment:Splign:2.1.0"
     exon            893..2953
                     /gene="Qrfprl"
                     /gene_synonym="C130060K24Rik; Gpr103b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtcgtgga acttgaccgc ggagcagctc tcggcgctgc ttcggctgca caacctgacg
       61 cgcgctcagt tcatcgcgca ctatgggctg cggccactgg tgctcacccc gcagcttccc
      121 gcgcgcgcca ggctggccct cctgctggtc ggcatgctca tctttgccct ggcgctcttc
      181 ggcaacgccc tggtagtcta tgtggtgacc cgcagcaagg ccatgcgcac cgtcaccaac
      241 atcttcatct gctccctggc actcagcgac ctgctcatcg tcttcttctg catcccggtc
      301 accatgctcc agaacgtctc ggacacctgg ctggggggtg ccttcatttg caaaatggtc
      361 ccatttgtcc agtgcactgc cattgtgaca gaaatcctta ctatgacctg cattgctgtg
      421 gaaaggcacc agggacttgt ccatcctttt aaaatgaagc ggcagtacac caatcaaaga
      481 gctttcacaa tgctaggtgt ggtgtggctg gtggccatca tcataggatc acccatgtgg
      541 catgtgcagc gacttgagat taagtatgac ttcctatatg aaaaagaaca catctgctgc
      601 ctggaagagt ggagcagccc cgtgcaccag aagatctaca ccaccttcat ccttgtcacc
      661 ctcttcctgc taccactgtt gctgctctct gtcctctacg ggaaaatcgg ttatgagctt
      721 tggatcaaga aaagaatcgg ggatggctca gtgctccgaa ctattcatgg aaaagaaatg
      781 ttcaaaatag ccagaaagaa gaagcgagct gtgatcatga tggtgacagt cgtggttctc
      841 tttgctgtgt gctgggcacc tttccacatc gttcacatga tgattgaata cagtaatttt
      901 gaaaaggaat atgatgaagt cacaatcaag atgatttttg ctatagtgca aataattgga
      961 tttttcaact ccatctgtaa tcccattatt tatgcactta tgaatgaaaa cttcaaaaaa
     1021 aactttgtgt ctgccgtttg ctattgcatt gtgaaggaaa caccttcttc agcacggaag
     1081 catggaagtt caggagctat ggtgatgcac aggagggcaa agttagctgc aagagagaat
     1141 cctgtagaga tcaaaggaga agcatttggg ggcagcaaca tcgatatcaa gtggtgtgaa
     1201 cagccagaaa agaagaagag gagatcaaaa gtggcatctt gtcctcttta gttccgaatt
     1261 tctgagagct ctgctgtaga cgtgaacact gtaccaatgt cttcagaatg agtatctgtc
     1321 atactgtaat cgaaagaaaa tgattttgag aaaaagccag agagctttca tattaaaaat
     1381 gttgacaaac actcagaagg cagggacagg ggattcaaga gtttaaagtc atccttagct
     1441 gcacgataag tttgaggata acctgggcta caagagaccc tgtctcaaga agccataata
     1501 attaaaacaa ccatccttaa ctaatgataa tgacaaagta tttttccatt gaaaatacat
     1561 gtaagctgca attttgaaaa attattgaac cacccttgtg attaatagat gaagtttaaa
     1621 aaaatttaaa tgtgttttta ttgtatgtat atggttggtt tacctgtgta tatgtctttc
     1681 agtaacttgt ataaaactca atgatctcag ctagtaactt tcttctgtgt ggtcaatgtg
     1741 atatgatttc ctatatattg ctaaattgaa tgaaaacatt aacaattcat tttcttccta
     1801 gaatattaat ttaatagttg agcatcacac gtgactgccg aagttgtgcc tcattctttt
     1861 gcaaagaaag catgtaccaa agtcagaaag tccaaaaaag tggaggagca gccaaacatg
     1921 agtgcaactc agcaacacat agatcggagc ttcttacagc ccgagggacc atttctgtgc
     1981 tctcataacc cccttttttc tttttaaata tctatttctg tgcaaactga tgttgatacc
     2041 ggctctactt gatgaagtca ccaggaagct aaatgagaca cacgtagaaa agcattttgc
     2101 ggtctagagc agtcttgcat tcggaagcat tgtcctgttc atatatatct ccagcctctt
     2161 ctgtccctgc tctgagttta ttcttgacac tgtccaactt tttcctcata cacacatctg
     2221 cgttctttac tagagaagag tttgagggac ctcatgtatc gacagagttg atatataata
     2281 taaatagggt taaaatataa gtattagaga taagctctag tggtaggaaa gagctttcct
     2341 tacataagtg taacatgttg acgaggactg aactctacca tgaaattttg ccattccatg
     2401 actacccagg tttcttccct caaacccatt tagtcttctg actcccacat gtcacagatc
     2461 caggggccac catcatcaga gcacatgacc ctttcccatc aagcatctaa tactttcaaa
     2521 gcttagtcat atatccttgt agcctaaatg tttctgatgc ctccagtttc tagtcttgat
     2581 tgttttcagc tgataacaaa aatgtcaaga acacccaggc tgctttgtgg tttgagcatt
     2641 aaaacatggg aaccaaacaa ctgaggctac taactcctca gtacaacctc aactcctcag
     2701 gtgtgtcagc gaagcatgca tggaaaagat gaagatgaaa taatgtgtgg taatagagga
     2761 ggggaaatgc caagatgaca gtaaaattat caaatcaaaa agagggaggc tggatcatgt
     2821 gtttgggaac ggattgttta ggtcgtactg tgaactgtgt gtctgttgtg cctagctatc
     2881 ctgttacaaa gcagtgtttt gttaaaacac caaaaattaa aataaatcca aatcactgtc
     2941 tttggttacc ttc
//
