LOCUS       NM_029011               3119 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus pyridine nucleotide-disulphide oxidoreductase domain 2
            (Pyroxd2), mRNA.
ACCESSION   NM_029011 XM_001003363 XM_001003369 XM_001003372 XM_193941
            XM_901591 XM_901592 XM_901594 XM_917735 XM_925181 XM_978776
            XM_978812 XM_978854 XM_978901
VERSION     NM_029011.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3119)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3119)
  AUTHORS   Ghazalpour,A., Doss,S., Zhang,B., Wang,S., Plaisier,C.,
            Castellanos,R., Brozell,A., Schadt,E.E., Drake,T.A., Lusis,A.J. and
            Horvath,S.
  TITLE     Integrating genetic and network analysis to characterize genes
            related to mouse weight
  JOURNAL   PLoS Genet 2 (8), e130 (2006)
   PUBMED   16934000
REFERENCE   3  (bases 1 to 3119)
  AUTHORS   Wang,S., Yehya,N., Schadt,E.E., Wang,H., Drake,T.A. and Lusis,A.J.
  TITLE     Genetic and genomic analysis of a fat mass trait with complex
            inheritance reveals marked sex specificity
  JOURNAL   PLoS Genet 2 (2), e15 (2006)
   PUBMED   16462940
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK038414.1, AK160239.1, CX218741.1 and CB573340.1.
            
            On Feb 16, 2007 this sequence version replaced NM_029011.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK160239.1, BC140971.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-627               AK038414.1         2-628
            628-943             AK160239.1         344-659
            944-1698            AK160239.1         661-1415
            1699-1736           CX218741.1         645-682
            1737-2233           AK160239.1         1454-1950
            2234-2658           CB573340.1         226-650
            2659-3119           AK160239.1         2374-2834
FEATURES             Location/Qualifiers
     source          1..3119
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 36.56 cM"
     gene            1..3119
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /note="pyridine nucleotide-disulphide oxidoreductase
                     domain 2"
                     /db_xref="GeneID:74580"
                     /db_xref="MGI:MGI:1921830"
     exon            1..439
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             313..2058
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /codon_start=1
                     /product="pyridine nucleotide-disulfide oxidoreductase
                     domain-containing protein 2"
                     /protein_id="NP_083287.2"
                     /db_xref="CCDS:CCDS37991.1"
                     /db_xref="GeneID:74580"
                     /db_xref="MGI:MGI:1921830"
                     /translation="MAAGGRGLIRALHSSPCPTWKRAQSGANGRLKPEYDAVVIGAGH
                     NGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIIPGFKFSRASYLLSLLRPQICTDL
                     ELKKHGLKLHLRDPYSFTPMLEEGTLNRLPRSLLLGTDMAANQKEISQFSRKDAQAFP
                     RYEEFMKRLVLAIDPLLDAAPVDTTAFQHGSLLQRLRALSTLKPLLKAGRTLGAQLPQ
                     YYEVLTAPISKVLDQRFESEPLKATLATDAVIGAMTSPHTPGSGYVLLHHVMGSLEGT
                     QGAWSYVQGGMGALSDAIASSAATRGASIFTEKTVAKVQVNSEGRAQGVTLQDGEEVR
                     SRVVLSCASPQVTFLELTPQEWLPGAFVKRISQLDTQSPVTKINVAVDRLPNFQAAPN
                     APGDQPQGHHQCSIHLNCEDTLLLHQAFEDAKGGLPSQKPMIELCIPSSLDPTLAPPG
                     CHVVSLFTQYTPYTLAGGKVWNEQEKNTYADKVFDCIEAYAPGFKRSVLARDILTPPD
                     LERIFRLPGGNIFHGAMSLDQLYFARPVPQHSDYRCPVQGLYLCGSGAHPGGGVMGAA
                     GRNAAHVVFRDLKNM"
     exon            440..459
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            460..553
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            554..627
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            628..783
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            784..937
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            938..999
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1097
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1239
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1374
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1447
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1604
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1759
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1760..1866
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1867..1987
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1988..3119
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2336
                     /gene="Pyroxd2"
                     /gene_synonym="3830409H07Rik; 4833409A17Rik"
ORIGIN      
        1 tagcccacta ccgggcctgg gagaacctag ttaaattgtt ctctctttgg tccctactcg
       61 cttgactcct ggaggctact cagactctgc cacctactcg cttgactcct cgaagctact
      121 cagactctgc cagttcttag cctacatgcc ccctcctcta ggctggcttg cgcaaactca
      181 gagccgcaga agctcggacc ctgggaaacg gtggcccaag gccaaggctg acactgaact
      241 gtaactccca gcccctcccc ttgcctgggc ctctggaaag ctgactgtgc aagcaaattg
      301 ctgggggcag aaatggctgc cggcggccga ggtctcatca gggccttgca ctcctctccc
      361 tgccctactt ggaaacgagc tcagtcggga gccaacgggc gcctgaagcc cgagtacgat
      421 gccgtggtga taggagcagg acacaatggg ctggtggctg cagcgtacct ccagagactg
      481 ggggtgaaca ccgcggtctt cgagaggcgc catgtgattg ggggcgcagc tgtcacggag
      541 gagatcattc ctgggttcaa gttctcccga gcatcctatc tcctgagcct actgaggcca
      601 cagatttgca cagacctgga gctgaagaaa cacgggctga aacttcatct gagagacccc
      661 tactccttca cccccatgct ggaagagggc acactgaaca ggctgcccag gtcccttctg
      721 ctgggcacag atatggctgc aaaccagaag gaaatctctc agttctcacg gaaggatgct
      781 caggctttcc ccagatacga ggagttcatg aaacgcttgg tgctagccat tgacccccta
      841 ctggatgcag ctccagtgga cacaacagcc tttcagcatg gctctctgtt gcagaggctc
      901 agggcactgt ccaccctgaa gcccctgctg aaagcagggc gcaccctggg agcccagctt
      961 ccccaatatt atgaggtcct cacagccccc atttccaagg tgctggacca acggtttgag
     1021 tctgagcctc tgaaggcaac tctggcaaca gatgctgtga ttggagcaat gacgagtccc
     1081 cacactccgg ggagtgggta tgtgctgctg catcacgtga tgggtagcct ggaggggacg
     1141 cagggcgcct ggagctacgt ccagggtggc atgggcgccc tctctgatgc catcgcgagc
     1201 tcggctgcta cacgtggagc aagcatcttc acagaaaaga ctgtggctaa ggttcaggtg
     1261 aacagtgaag gccgtgccca aggagtcaca ctgcaggacg gcgaggaggt cagaagcaga
     1321 gtcgtcttgt cctgcgcgtc accacaggtc accttcttag agctgacacc acaggagtgg
     1381 cttcccgggg cttttgtgaa gagaatctcc cagctggaca cccagtctcc tgtcaccaag
     1441 atcaatgtgg ctgtggacag gctgccaaac ttccaggcgg cccctaatgc tcccggggac
     1501 cagccccaag gtcaccatca gtgttccatc cacctgaact gtgaagacac cctgctcctc
     1561 caccaggcct ttgaagatgc caagggtggc ctgccttccc aaaagcctat gattgaactc
     1621 tgcatccctt catcgctgga ccctaccctg gctccaccag gctgccatgt tgtctccctc
     1681 ttcactcagt atacacccta caccctggca ggaggcaagg tctggaatga gcaggagaaa
     1741 aacacctatg cggacaaagt gtttgactgt atcgaggcct atgcccccgg cttcaagaga
     1801 tctgtgctgg ccagagatat tctcacccca ccggatctag agagaatctt caggcttcct
     1861 ggagggaaca tattccacgg tgccatgtcc ctggaccagc tctactttgc ccgtccagtg
     1921 ccccaacact ctgactacag atgcccagtg cagggcctgt acctctgtgg gagtggggcc
     1981 catcctggag gaggcgtcat gggagcggct ggacggaatg cggcccacgt agtctttaga
     2041 gacctcaaga acatgtgacg ctggaccagc tctgaccctg gggaggaaag ttttcctgca
     2101 cgttgagcca ccgagcaggc catctgccca agacgccctg ctcccaagga ggccattgga
     2161 gacaaactgt actagcaagg tgccatctgt tccttaatca gagactcagt tgtatttagc
     2221 acaatctcac ctgtggccca ggtgtccatg gatcagctgg gtttgtctca cctgtgcctc
     2281 aggtgtccat ggatcagctg ggtttgtctt tttaaaaacc atgttttgta tagagactgc
     2341 ttgtattgtt tttctgtgtc tatagcttgg gggaacttgg cacactagtt ggacacagtc
     2401 catctaatgc atggaaaaat ttggaccaac atccaactgt tcccttctta tcagcgggtt
     2461 tcccactacc aactgattga aggcctggcc taccaatgcc cagtcaacta ccgtcatatt
     2521 cctgtcacta taaaacaaac tcacagtgac tcacaagctc tctctcgggc ccacacgatg
     2581 ggcccgagca aaggtctgca tctcaagccg tcaaaacctc tggtcaggaa atagcagttg
     2641 agggtgactg tagagtgggc tcaccagaaa ctgcaggaac cgctttctac cttctgcctg
     2701 ccaggtacta aatctgccat gtccgacact aaacctttca acctaaaaag gcctcattct
     2761 gcagtgagtt gggctgtcac tgccagaaag aaacacagga cagttccatg aataacaact
     2821 gtgctggcag cctctgcatg cgggtcaaag gccaccatcc taagctgtcc cctctgaagg
     2881 tcagacagag gcttcctagg actcttacac ctaccttctt ctgcacagtc agttaccact
     2941 ggacaacact ctggtcagcc tttcaggcaa ccaggagaca ttttcatatt cttaatgtga
     3001 tgtatgtatg tctttctttg aagttacttt atgtcaaaaa ctatccagtg ttcttttgaa
     3061 aacattttaa tagctgtctg atattccctc gtggcaaata aaccataatt tactgtggg
//
