LOCUS       NM_001170869            1165 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus PYM homolog 1, exon junction complex associated factor
            (Pym1), transcript variant 2, mRNA.
ACCESSION   NM_001170869
VERSION     NM_001170869.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1165)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1165)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
REFERENCE   3  (bases 1 to 1165)
  AUTHORS   Gatfield,D. and Izaurralde,E.
  TITLE     REF1/Aly and the additional exon junction complex proteins are
            dispensable for nuclear mRNA export
  JOURNAL   J Cell Biol 159 (4), 579-588 (2002)
   PUBMED   12438415
REFERENCE   4  (bases 1 to 1165)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BI989958.1 and AC131081.7.
            
            On Dec 1, 2011 this sequence version replaced NM_001170869.1.
            
            Transcript Variant: This variant (2) contains an alternate 5' exon
            and thus differs in the 5' UTR and 5' coding region, compared to
            variant 1. The encoded isoform (2) has a distinct N-terminus and is
            shorter than isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BI989958.1, BC049647.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-600               BI989958.1         1-600
            601-1165            AC131081.7         106838-107402
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 77.14 cM"
     gene            1..1165
                     /gene="Pym1"
                     /gene_synonym="A030010B05Rik; Pym; Wibg"
                     /note="PYM homolog 1, exon junction complex associated
                     factor"
                     /db_xref="GeneID:78428"
                     /db_xref="MGI:MGI:1925678"
     exon            1..112
                     /gene="Pym1"
                     /gene_synonym="A030010B05Rik; Pym; Wibg"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..687
                     /gene="Pym1"
                     /gene_synonym="A030010B05Rik; Pym; Wibg"
                     /note="isoform 2 is encoded by transcript variant 2;
                     partner of Y14 and mago; protein wibg homolog; within bgcn
                     homolog"
                     /codon_start=1
                     /product="partner of Y14 and mago isoform 2"
                     /protein_id="NP_001164340.1"
                     /db_xref="CCDS:CCDS48730.1"
                     /db_xref="GeneID:78428"
                     /db_xref="MGI:MGI:1925678"
                     /translation="MATPYVTDETGGKYIASTQRPDGTWRKQRRVKEGYVPQEEVPVY
                     ENKYVKFFKSKPELPPGLSPEATTPVTPSRPEGGETGLSKTAKRNLKRKEKRRQQQEK
                     EAEALSRTLDKVSLGDTAQIPSALQGPQATPLAASDPSDSAATTEKAKKIKNLRKKLR
                     QVEELQQRIQAGEVSQPSREQLEKLARRRVLEEELEDLELGL"
     exon            113..206
                     /gene="Pym1"
                     /gene_synonym="A030010B05Rik; Pym; Wibg"
                     /inference="alignment:Splign:2.1.0"
     exon            207..1165
                     /gene="Pym1"
                     /gene_synonym="A030010B05Rik; Pym; Wibg"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1141..1146
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pym1"
                     /gene_synonym="A030010B05Rik; Pym; Wibg"
                     /note="hexamer: AATAAA"
     polyA_site      1159
                     /gene="Pym1"
                     /gene_synonym="A030010B05Rik; Pym; Wibg"
                     /note="major polyA site"
ORIGIN      
        1 ggatgaggac tccacttccg gcggggaggg gggcgggacc ccagcccgct cacgccggaa
       61 gtggttcggg ttctcaagat ggcgactccc tatgtaactg acgagaccgg cggcaagtac
      121 attgcctcaa cacagagacc cgacgggacg tggcgaaagc agcggagggt caaagaagga
      181 tacgtgcccc aagaggaggt cccagtctat gaaaacaagt atgtgaagtt tttcaagagt
      241 aaaccagaac ttcccccagg gctgagccct gaggccacca caccggtcac cccatccaga
      301 cctgaaggtg gtgagacagg cctctccaag acagccaaac gaaacctgaa gcggaaggag
      361 aagaggcggc agcaacagga gaaagaagca gaggccttga gcaggactct tgataaggtg
      421 tctctgggag acacagccca gatacctagt gctctccaag gcccccaggc cacgcctcta
      481 gctgcctctg atccatccga ctctgctgcc accacagaga aagccaagaa gatcaagaac
      541 ctgaggaaga agcttcggca ggtggaggag ctgcagcaac gcatccaggc cggggaggtc
      601 agccagccca gcagagaaca gctggagaag ctggctcgac ggagggttct ggaggaggag
      661 ctggaggact tggagttggg cctgtgaggc ttcaggagta ggggagtgga ctgcagaaca
      721 aaccatgggg tgctctgggg tccagggagt gtgggccgca gcagtcagga ggggtacccc
      781 catactgact cacctccacc tcctgtggcc cgactccgtc ctccagagcc taggctctct
      841 ttcatccctt ccacttcttc tcagctcctg tttttggact ttccccttcc atcccagtgt
      901 tcacaatctg agtgccgacc tgaggtacct ctgctgctga tctgggtgtc ttgttgaaaa
      961 ggaaaccggg ggggtgggag tctgttagcg atctgaggct gagggtatag cagtacccat
     1021 gttttggagt cttagttcct gttcacagtg tttatgaatt acttccctga ccatcccgat
     1081 ttccccccac cccacccccc acgcccctta attttttttt tttttttttt taaagaaaag
     1141 aataaattga agtagatgac atgtg
//
