LOCUS       NM_001164630            4600 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus PWWP domain containing 3B (Pwwp3b), transcript variant
            1, mRNA.
ACCESSION   NM_001164630
VERSION     NM_001164630.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4600)
  AUTHORS   Narumiya,H., Hidaka,K., Shirai,M., Terami,H., Aburatani,H. and
            Morisaki,T.
  TITLE     Endocardiogenesis in embryoid bodies: novel markers identified by
            gene expression profiling
  JOURNAL   Biochem Biophys Res Commun 357 (4), 896-902 (2007)
   PUBMED   17462595
REFERENCE   2  (bases 1 to 4600)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY713797.1, AL732419.6 and BC068178.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1, 2, 3, 4, and 5 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.76123.1,
                                           SRR7345562.2485597.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-74                BY713797.1         1-74
            75-75               AL732419.6         165173-165173
            76-548              BY713797.1         76-548
            549-4598            BC068178.1         150-4199
            4599-4600           AL732419.6         193389-193390
FEATURES             Location/Qualifiers
     source          1..4600
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 61.29 cM"
     gene            1..4600
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /note="PWWP domain containing 3B"
                     /db_xref="GeneID:245631"
                     /db_xref="MGI:MGI:2445062"
     exon            1..174
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            175..242
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            243..319
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            320..467
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            468..596
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            597..763
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /inference="alignment:Splign:2.1.0"
     exon            764..4600
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             980..3025
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /note="mutated melanoma-associated antigen 1-like protein
                     1; PWWP domain-containing protein MUM1L1; melanoma
                     associated antigen (mutated) 1-like 1; MUM1-like protein
                     1"
                     /codon_start=1
                     /product="PWWP domain-containing DNA repair factor 3B"
                     /protein_id="NP_001158102.1"
                     /db_xref="CCDS:CCDS30432.2"
                     /db_xref="GeneID:245631"
                     /db_xref="MGI:MGI:2445062"
                     /translation="MDGKYVLCNWKDQLWPAKVLDRSESPSESKRKNTSSLEVEILSL
                     DEKITVESTDTKVLSKSAVEAIMSSLAVQSEVIIAPREETAYERSLKMALEMVKEGTN
                     LSQESMSEEQPTATASENVPEQPPDSPPHKKFRKLESNTQEDSASILLCSESDDSMTD
                     DKLQVHTTGESMPSEMDTKATENLGCCQTDPSLADEDDKKEEKKKIDISAIMSVNLSL
                     KEESEYIKEEKFVPSSEDLTVPKEESQDILPEAPLAVSSECSIVSENNMEDPGEGPSN
                     QNLVSYANQNQSSVESDVGAETSTAGCSGDFQVSLPTRDTVSSDLLLQRLDLEDLEEE
                     ARASGKLLSLNPASAAALENDNEDDDEDLPRFILHYETRAFETGMIVWFKYQKYPFWP
                     AVIKSIRRKERKASVLLVEADMSPQKKGVRVSLRRLKKYDCKEKQALVEKAREEYRES
                     IDWCVSLICDYRVRLGCGSFTGSFFEYYAADISYPVRKIIKQDTFRNIFPKLYNENVG
                     EQLPMASQAKRVSFQKILPDRMKPARDRANKNLVDFIVNAKGTEDHLLGILKGTKKSK
                     WLKSFLNAKSFTPCIETYFEDEDQLDEVVKYLQEIYKQIDQKMLTLIKDDKIKFVLEV
                     LLPEAIICSISAVDGLDYEAAEAKYLKGPSLGCRERELYDSKILFEKRRRSLPNEGH"
     regulatory      3914..3919
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /note="hexamer: TATAAA"
     polyA_site      3933
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /note="major polyA site"
     regulatory      4577..4582
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /note="hexamer: AATAAA"
     polyA_site      4598
                     /gene="Pwwp3b"
                     /gene_synonym="9430086K21Rik; Mum1l1"
                     /note="major polyA site"
ORIGIN      
        1 gctcgcggct cgcacccaac tgactgttgc ttcgtgaggg agagactgcc taagggagag
       61 cctctctggt ggccgagggg cggcggcggc ggcggcagcg gcggccgcga caggcgccag
      121 aggctgcgtc ttcaggcctg tccgggagaa ttgttgcaga attcggtgtg aaaggtgatc
      181 tctttctaca tctctgctta cctatcaaga ggatgaatcc tgaatggcat aaaatataaa
      241 aggtgcttga gcagctgccc acatgcatcc cattgtccta agctacagct ggattttcct
      301 gtggatctga gaaggctggt cctgcctgtg ataccacttg tgaccagaac agcagtgcgg
      361 ccatacaagt acccagaagg gtgaaggctc tgctgggcaa acagctgaag tgtgaatcaa
      421 aacagctggg ccatagtgtc agactaccaa agtgcctgtg acagagggga gtggccttca
      481 gctctgcgtc accgtagggg cggagcctgc tctaagcagt gtctgtgagt tctgtccggc
      541 cagccttggg ggaggagctg catttgacta ggctgcagct gacaagaagc ttcaagcctc
      601 ggttaatagc agagttgcat gtgattggac ttgagcccag aaaggcagta taactacata
      661 cgtgccccat agggtgaaag gccttcttgg aagtcagctg cctgaggatc aagatacttg
      721 gctgtcacat tgcaagacta cccaacagtc cacctgacag aggtatcttc cagagttctc
      781 ttattcaaac aacatgttca agaatcctgc ggacatattc gtggaagaaa acggtgcaca
      841 taagccataa actcttgtgg tgccaaatca aagagaaact ttaatcagac tggtttcttg
      901 atagcacttg tatttgcagc cacagggcta gccaatctct ttgtctgtaa tactacttgg
      961 cacactaatc taaatcataa tggatggcaa atatgtcctg tgtaattgga aagaccaatt
     1021 atggccagca aaagttttag ataggtctga aagtccatca gagagtaaga ggaaaaatac
     1081 atcgtcccta gaagttgaaa tactttcact ggatgagaaa attaccgtgg aaagcacaga
     1141 cacaaaagtc ctaagcaaat ctgctgttga agccattatg tcctctctag cagtacagtc
     1201 agaggtcatc attgcaccta gagaggagac agcctatgaa agatcactga aaatggcact
     1261 ggaaatggtg aaagaaggaa ccaatctcag ccaggaaagc atgtcagaag aacaacctac
     1321 agctacagcg tctgaaaatg tgccagaaca gccacctgat tcacctcctc ataaaaagtt
     1381 ccgcaaactt gaaagcaaca cccaggagga ctctgcttcc atactgctgt gctcagagag
     1441 tgatgattcc atgaccgatg ataagttgca ggtgcacaca accggtgaga gcatgccaag
     1501 tgagatggac acaaaggcaa cagaaaactt aggctgttgc caaacagacc cttccttggc
     1561 agatgaggat gataaaaagg aagaaaagaa aaagattgac atctcggcaa tcatgtctgt
     1621 gaatttatca ctcaaagaag aaagcgaata tattaaagaa gagaaattcg tcccctcatc
     1681 agaagatctc actgtcccca aagaggagtc acaagacatc ctcccagaag cgcctctggc
     1741 tgtttcctct gaatgttcta ttgtctcaga gaataacatg gaagatcctg gtgagggccc
     1801 atcaaatcag aatctagtct cctatgccaa ccaaaatcag tcttctgtgg aatccgatgt
     1861 aggtgccgag acatccactg cagggtgctc aggggacttt caggtttccc ttcctacccg
     1921 tgatacagtc agcagtgatc tactgctcca gagactggat ctagaagatc ttgaggaaga
     1981 agcccgagct tcaggcaagc ttttgtcttt aaatcctgcc agtgccgctg cgttagaaaa
     2041 tgataatgaa gatgatgatg aagaccttcc acgtttcatc ctccattatg agacacgtgc
     2101 atttgaaact ggaatgatag tgtggtttaa atatcaaaaa tacccatttt ggccagcagt
     2161 gatcaaaagc attaggcgga aagagaggaa agcgagtgtg cttttggttg aggcagacat
     2221 gagtcctcaa aagaaaggcg ttagagtatc tttgaggagg ctgaagaaat acgactgtaa
     2281 agagaaacag gcactagtgg agaaagccag ggaggagtac cgggagagta tcgattggtg
     2341 cgtgtcactg atttgtgact accgagttag actaggttgt ggctctttta ccggctcgtt
     2401 ctttgagtat tatgctgctg acatcagtta tccagtcagg aaaatcatca aacaagatac
     2461 cttcagaaat atatttccaa agctatacaa tgaaaacgtg ggggagcagt tgcctatggc
     2521 atcccaagcc aagagagtat ctttccagaa aattctccct gatcggatga agcctgctcg
     2581 ggaccgagct aacaagaacc tggtagattt tattgtcaat gcaaaaggaa cagaggacca
     2641 cctcttgggc attttaaagg gcaccaaaaa atccaagtgg ctgaaatcat ttctcaatgc
     2701 aaagagtttc acaccctgta ttgaaaccta ctttgaagat gaagatcaac tggatgaggt
     2761 agtgaaatac ctacaagaaa tttataagca aattgaccag aagatgctga ctctgataaa
     2821 agatgacaaa attaagtttg tcttggaagt tcttctacca gaagcaatta tttgctcaat
     2881 ttctgctgtt gatggcttag attatgaggc agctgaggca aagtatctaa agggaccatc
     2941 cctcggctgt agggagagag aattatatga ttccaaaatc ctatttgaaa agagaaggag
     3001 gtcattacca aacgaaggcc attaatgcca agagttggaa ccaaaaatgg aagctagatg
     3061 aagctttgga aaagtaatct tctaaaagtc ccaatgccta agtatttgcc gaaaatgaag
     3121 ggagggtctt tgaattctaa gttcttttat ttttttttga agatctgtgt gacctacaaa
     3181 taccagtaca tctactttta ttttcttgtg cttcgtcaca ttcagcttga tcaggatatt
     3241 tttagcagtt tgactttcta atagattttg gaatgcataa ttcttaagca actttagcag
     3301 aaactgttat tttgttttaa gatatttttg cgtctttgct gtataggtaa atacattata
     3361 cacattcagt tcaataaaac tgcactggtg ttagatttta agcaaaagaa ttagaaaaga
     3421 tgtctaaaat accagttata tattttttgg tcaatttttt ttataaagta ctgacttttc
     3481 tcttaagata gccaatttat ttttcctgcc atgcctattt atttttggga aaaatatctc
     3541 taaatcatag aaccaaagat agattaaaat ttgccatata tataactaac cacaattgct
     3601 tttgcaagaa aacaatctaa aattaaaaag taaatgggtt atccacatgt aatctatctg
     3661 tttgtatgta tgtgtataac atctcagcat gcagaaaatg gttgttcatt ctacacttct
     3721 atgaaattcc agtttgaaga gtgtcaaagc taaataactt cctaaaacag ataagcttct
     3781 ggctatcttc attattgtga gtagttctta atctagcaat ttgagcgtat gtagaaaaca
     3841 gttaagatca gcgtgtcaac agtatagcca cactacagtc cagagttgtt gcttcaaatc
     3901 catctaagtt tgatataaac ttaagaaaag caagcactgt gtttagagtc ctttctccaa
     3961 atataaagtc atttgtctcc aaccaagcaa gctttagcat ctggcttatt tctagaatgg
     4021 ttctaattgg ttccaataac ataaatgcca actggtaaat cattccaacc tactagatgg
     4081 accagaaact ggaaaattgg aaaaacgttc cagcaaaagg tcttcacttg ctacatgtgg
     4141 cagttattct gtatatggtt atggtgtata caaaattagt cgttcttgtt acttgaaaca
     4201 agattttttt ataagactca atcttagaaa agctagtata ttacaaaact tgatgtgaaa
     4261 agatatacta agggcttaac ataaacctat ctccattttt acctcagaga gtgagacaac
     4321 tttcactctt gggctctttt atgttcatct cacacagctc tatgtttatg tacaatttgc
     4381 agaatttggg tatttgattt ataataaaac taacatatcc ttcaatttag atgttcattt
     4441 cacttgagtt aaataaaaac attgtggtgt ttgtgtaaat taatatatgt acaagcatat
     4501 atatctacgt gtacacacac ttcatttaaa acttgtaagc gtcatcattt aactcttgtt
     4561 ataagttgac attctaaata aaatgcccac tttcatgatt
//
