LOCUS       NM_023431               5079 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus PWWP domain containing 3A, DNA repair factor (Pwwp3a),
            mRNA.
ACCESSION   NM_023431
VERSION     NM_023431.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5079)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5079)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140229.3.
            
            On Jan 10, 2023 this sequence version replaced NM_023431.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK158750.1, SRR13422600.231368.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                AC140229.3         76826-76857
            33-149              AC140229.3         78475-78591
            150-235             AC140229.3         79148-79233
            236-306             AC140229.3         80210-80280
            307-1116            AC140229.3         82391-83200
            1117-1221           AC140229.3         84376-84480
            1222-1292           AC140229.3         86264-86334
            1293-1369           AC140229.3         88468-88544
            1370-1430           AC140229.3         89013-89073
            1431-1506           AC140229.3         90073-90148
            1507-1557           AC140229.3         90545-90595
            1558-1994           AC140229.3         90917-91353
            1995-2083           AC140229.3         91950-92038
            2084-5079           AC140229.3         93739-96734
FEATURES             Location/Qualifiers
     source          1..5079
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..5079
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /note="PWWP domain containing 3A, DNA repair factor"
                     /db_xref="GeneID:68114"
                     /db_xref="MGI:MGI:1915364"
     exon            1..32
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            33..149
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..2141
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /note="mutated melanoma-associated antigen 1; PWWP
                     domain-containing protein MUM1; melanoma associated
                     antigen (mutated) 1"
                     /codon_start=1
                     /product="PWWP domain-containing DNA repair factor 3A"
                     /protein_id="NP_075920.4"
                     /db_xref="CCDS:CCDS24014.1"
                     /db_xref="GeneID:68114"
                     /db_xref="MGI:MGI:1915364"
                     /translation="MTDAKYVLCRWGKRLWPAKVLARTETSAKNKKKKEFFLDVQILS
                     LKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERT
                     SLSPESHPIEDGITLSQKEKTDADVASQVSSAPSPSLLGEDGQAVVAQCASKRRSEYS
                     SKSLLPSSALEDHLRCQVGPKTGLSESGAGDKSQDDSGLQLDHGQESTTKKRQRNLGE
                     KPTRRRRSESGLSKGESVLKSQGQASSCVALASPRPPSQTRDEEPCAGVKGCDWVKSS
                     GNIRPLSASERSRGCPTKRPRLDGGQNPPTRQLGTRTVGAAPCPRSCSGEVTMLCSAG
                     AGDKPEEDPVSSEESTGFKSTHSLLEEEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQ
                     KYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHALLDRAK
                     EDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQL
                     GKGDPEEPVGDSQLGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILH
                     SRKPSRWLKTFLSSSQCVTCMETYLEDEAQLDEVVEYLQGVCRDMDGQVPERGSGDRI
                     RFILDVLLPEAIICAISAVEAVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR
                     "
     exon            150..235
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            236..306
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            307..1116
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1221
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1292
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1369
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1430
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1506
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1557
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1994
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2083
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     exon            2084..5079
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2380..2385
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /note="hexamer: TATAAA"
     polyA_site      2399
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
                     /note="major polyA site"
     polyA_site      2524
                     /gene="Pwwp3a"
                     /gene_synonym="2610019J09; 9430059D04Rik; MUM-1; Mum1;
                     UBE-1C2"
ORIGIN      
        1 agcccgcggg gatctgcgcg gcggcggagg cggggacctc tggcctcagt caagcctgta
       61 ccaccgcacg cccagatact cctttctgag tcatgacgga tgccaagtat gtcctctgcc
      121 gatgggggaa gcgactgtgg cctgcgaagg ttttggccag aaccgagact tcagcaaaaa
      181 acaagaaaaa gaaggaattc ttcctagatg ttcagatact ctcgctgaag gaaaagatcc
      241 aggttaagag ctcagccgtg gaggccctgc agaagtcgca cattgagaac attgctgcct
      301 tcctggcctc tcagaatgaa gtcccagcta ctcccctgga ggagctgact taccgacgct
      361 ccctgcgagt ggccctggat gtcttgaatg agaggaccag tttgagtcct gaaagtcatc
      421 caatagaaga tgggattaca ctgtctcaga aggagaaaac agatgcagat gtggcctcgc
      481 aggtctccag tgctccttct ccatctctcc tcggtgaaga tggtcaagcc gtggtagccc
      541 agtgcgcatc caagaggagg tcggagtaca gttcaaaaag cctgttgccg tcgtctgcat
      601 tagaagatca tctcaggtgc caagtgggcc ccaagacagg cctctcagag agtggagctg
      661 gagacaagtc tcaggatgat tctgggttac agctggacca tgggcaggag agcacaacca
      721 aaaagaggca gaggaatttg ggagagaaac ctacccggcg ccgaagatca gagtctggcc
      781 tttccaaggg agaaagtgtc ttaaagagcc agggacaggc atccagctgt gtggccctgg
      841 cttcacctag gccgccctcc caaaccaggg acgaggagcc ctgtgccggg gtcaaaggct
      901 gtgactgggt caagtcatca ggcaacatca ggccactctc ggcctctgag agaagcagag
      961 gatgccccac aaagagacca cgcttggatg gaggccagaa cccacctacc aggcagctgg
     1021 ggactagaac tgtgggggca gcgccctgcc ctaggagctg ttctggggag gtcacgatgc
     1081 tgtgcagtgc tggagcgggt gacaaaccag aggaagatcc tgtgtcctca gaagaatcca
     1141 cagggttcaa gtccacacac tccctgctgg aggaggagga ggaggaagag gaggaaccac
     1201 ctcggatcct tctgtatcac gaaccacggt catttgaagt aggaatgctg gtctggctta
     1261 aataccaaaa atacccattc tggccagctg tggtcaagag tgtccggcga agagacaaga
     1321 aggccagtgt gctcttcatt gagggcaaca tgaaccccaa gggccgagga atcactgtgt
     1381 cgctgcgacg gctcaagcac tttgactgca aggaaaagca cgcactgctg gacagagcca
     1441 aggaggactt tgcccaggcc attggctggt gtgtttcact catcactgac taccgtgtgc
     1501 ggctgggatg cggctccttt gctgggtctt tcttggaata ctacgctgct gatatcagct
     1561 accctgtgcg caagtctatc caacaggacg tcctggggac caggtttcct cagctgggca
     1621 agggggaccc tgaggagcct gtaggggaca gccagctggg acagtggcgg ccatgcagga
     1681 aggtgctgcc tgaccgctcc agggctgcac gggatagagc caaccagaag ctggtggagt
     1741 acatcgtgaa ggccaagggt gcagagagcc acctgcgggc tatcttgcac agccgcaagc
     1801 cctcacgctg gctgaagacg ttcctgagct ccagtcagtg cgtgacttgc atggagacat
     1861 acctggagga tgaggcgcag ctggatgagg tggtggagta cctgcagggc gtctgcagag
     1921 acatggacgg ccaggtgcct gagcgcggca gtggagaccg cattcgcttc atcttggatg
     1981 tgctgctgcc cgaggcaatc atctgtgcca tttccgcggt ggaggcggtg gattacaaga
     2041 cagccgagca gaagtacatt cgtggcccca cacttagcta ccgggaaaag gaaatctttg
     2101 acaatgaact cctggaggag aggaaccgac gccgtcgctg atgccgcagt ctgcacctgg
     2161 ccggccagca ctgggtgtga cctgccagag gcctccacca ggcctaggag tgtgagaact
     2221 ttgacctgtg cgtgggttct acgtcttcag cctaagtctg ggagatcaga tgccatcaga
     2281 tgcctgctgc catctatgaa cagctgcttt ctggaagttt ctgtgtgttt ttgtgtatac
     2341 atgtgtatgt ctggttttat tttttttaat tattttgttt ataaatgcgt ttgaatgcat
     2401 atgtgtcata gtcattgcac agtgtggctg gcatgtgcgc tctatgtccc atgttgcttg
     2461 gtgtgcccgc cctacagaca tttctggaaa gactgacctg aacacgtgac tcccagagca
     2521 ttgacatgtt gccctggcat tcattgttct gcttatttcc tctccagttt ctggaatctt
     2581 ctctgcctct cctgtgtggt gagcaggcag tggggactct tgcaggaaca gtctttgcag
     2641 gtgggagatg ttagggaggt gggaacatgt ttgttcactg ggctccttgt agtcttgcaa
     2701 ggccgggcag gccagcagcg ttcatcccca ccccatgctc tctgttcccc tgcgccccca
     2761 gccaagcact gattacgcag ggctgccact ggcttctagc ctggccccac caccccacct
     2821 aaaaacctct tctggaccga ggatggtggg gatgacaata agaaaaggca gattcctgca
     2881 tggttgccat ggatgcacga tctcaccgtg gttgtgtgga agctctgtcc acccagagcg
     2941 agggtgaagc cactagtagc agtggacagc cctatgctga gctatgccag ccagctgcaa
     3001 agcccatagg atactcagcc aggtgttggg ttgctggata tggaacacat gggtgtcctt
     3061 gacacttgtg gccatcccag aatgagatgg ggatgattaa gcatcaccct agacccctgc
     3121 atcggacagc acatcgcgcc aggatggtat gagataggtg agtacagacg tggcctgtca
     3181 ggacaggcac agctgagcag cactgtctgt ggcctctcga ctcaaatttc tctaccatct
     3241 ttgttgaaat tggggtcacg gagaaccagg tcagagacct tgttcaggct gcagcttgtc
     3301 ctaccatcca tagggaccac ccgtggaagg gacactggat ttgaggtatc agaatattgc
     3361 tgtcagggcc ttctgcccag aagaggcctg atgccaggaa ctcagcttct tgttggcact
     3421 gggaaatggg tctgcccttg gtccatgtac agctctgtca gggagtgaga ggcttttcag
     3481 aaccgcaaga aacccagtgc aagttcctcc tcagtagcta cagtcttcac tgctgtgccc
     3541 gactgtggcc ttaagagtag cttctcctct gacgccctct tctggcgtgt ctgaagacag
     3601 ctacagtgta cttacatata ataaataaat aaataaatct ttaaaaaaaa aaaaaaaaaa
     3661 aaaaaaagag tagcttctcc ccaggacagg cttgtctcac actgggagtg gcacttcacc
     3721 tggccccact actcccctgt gtggtgggcc tggggcaaac aacaccctgc tttccacctg
     3781 gggtccatac acagaccatc ttggagacag aatggtcaca aattcagtca gggcctgcag
     3841 catctcccta gagcagcacc ttaaacaccc tttaaagccc tgcatcctgt gggtgacaat
     3901 ggcctgtatt tcaacttgtc tggaggccac atttctctct acaccttggg ttatgatctg
     3961 gctgatttgg aggggctgag ataccagata tgattccctc atccctgtct tgtcagtgcc
     4021 ccccacatcc tctgtgactc ccacatgccc ctcagggcct cagatctctg acaccagatg
     4081 ggtcactttt agggtatcca aggccctata gttgatgata ggtgcatcac tggccagcct
     4141 ataggacagg aatgtcccag ttgaagtggg cacattccct agacattacc cagtgtccca
     4201 cagctaggat tcaagaggcc ttttctcctc ctgtcccatt gtggtggaga taagcctgtg
     4261 gcctcttctg ccggttgata ttccttccct ccaaaaacct ctacaatccc tcggctccct
     4321 ggtgccatct agtggtattt tcccacctgt atctcaggga ccttaactcg tgtctcactg
     4381 gaagcccagg caccacaagg taaaaagact cagactcctc aagaagcagc agatgggcag
     4441 cagagacata gaggtcctga cccaggcaca ttagcgagtg gattgtggat cttttgtgcc
     4501 gtgccaggtg ctgcgccacg ccatgaaaat gggaagtgac cctaggtcca tcttgcctct
     4561 ctatcttgca ctgcagtgtc cttccccatc cacccctcct ccccttcctc ctcatctctt
     4621 cctgttccat catccccaac tttcttgccc acagctatca aagccccaag ctgccctttc
     4681 attccctcct gacctgttct tgtgatgtcc ttgaagctct ggattcctgc ctgagcacta
     4741 ctctgtttgc ctgactgctg tccatctgtc aggcaaccag acacactgac caatcctcct
     4801 caagccacag ctagagcatg tttcccagag cctggtgaca aggagtactc gtccatggtc
     4861 tgtagatggg gggtaatcaa gagggggcag ttgaggggct ggagagatgg ctagtggtta
     4921 agagcactga ctgcttttcc agaggtccag aattcaaatc ccagcaacca catggtggct
     4981 cacaaccatc tgtaatgaga tctgatgacc tcttctggtg tgtctgaaga cagctacagt
     5041 gtacttatat ataataaata aataaacctt ttaaaaaaa
//
