LOCUS       NM_001033490            1229 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus pseudouridylate synthase-like 1 (Pusl1), mRNA.
ACCESSION   NM_001033490 XM_001004412 XM_001476573 XM_001476588
VERSION     NM_001033490.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Busch,J.D., Cipullo,M., Atanassov,I., Bratic,A., Silva Ramos,E.,
            Schondorf,T., Li,X., Pearce,S.F., Milenkovic,D., Rorbach,J. and
            Larsson,N.G.
  TITLE     MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of
            Mitoribosome Composition
  JOURNAL   Cell Rep 29 (6), 1728-1738 (2019)
   PUBMED   31693908
  REMARK    GeneRIF: MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of
            Mitoribosome Composition.
REFERENCE   2  (bases 1 to 1229)
  AUTHORS   Bachmanov,A.A., Li,X., Reed,D.R., Ohmen,J.D., Li,S., Chen,Z.,
            Tordoff,M.G., de Jong,P.J., Wu,C., West,D.B., Chatterjee,A.,
            Ross,D.A. and Beauchamp,G.K.
  TITLE     Positional cloning of the mouse saccharin preference (Sac) locus
  JOURNAL   Chem Senses 26 (7), 925-933 (2001)
   PUBMED   11555487
REFERENCE   3  (bases 1 to 1229)
  AUTHORS   Max,M., Shanker,Y.G., Huang,L., Rong,M., Liu,Z., Campagne,F.,
            Weinstein,H., Damak,S. and Margolskee,R.F.
  TITLE     Tas1r3, encoding a new candidate taste receptor, is allelic to the
            sweet responsiveness locus Sac
  JOURNAL   Nat Genet 28 (1), 58-63 (2001)
   PUBMED   11326277
REFERENCE   4  (bases 1 to 1229)
  AUTHORS   Montmayeur,J.P., Liberles,S.D., Matsunami,H. and Buck,L.B.
  TITLE     A candidate taste receptor gene near a sweet taste locus
  JOURNAL   Nat Neurosci 4 (5), 492-498 (2001)
   PUBMED   11319557
REFERENCE   5  (bases 1 to 1229)
  AUTHORS   Li,X., Inoue,M., Reed,D.R., Huque,T., Puchalski,R.B., Tordoff,M.G.,
            Ninomiya,Y., Beauchamp,G.K. and Bachmanov,A.A.
  TITLE     High-resolution genetic mapping of the saccharin preference locus
            (Sac) and the putative sweet taste receptor (T1R1) gene (Gpr70) to
            mouse distal Chromosome 4
  JOURNAL   Mamm Genome 12 (1), 13-16 (2001)
   PUBMED   11178737
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL670236.9.
            
            On or before Jun 25, 2009 this sequence version replaced
            XM_001476573.1, XM_001476588.1, XM_001004412.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13861890.117720.1,
                                           SRR7652917.617202.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-132               AL670236.9         198221-198352       c
            133-190             AL670236.9         197948-198005       c
            191-378             AL670236.9         197642-197829       c
            379-528             AL670236.9         197343-197492       c
            529-699             AL670236.9         197089-197259       c
            700-754             AL670236.9         196259-196313       c
            755-917             AL670236.9         196024-196186       c
            918-1229            AL670236.9         195447-195758       c
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 87.66 cM"
     gene            1..1229
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /note="pseudouridylate synthase-like 1"
                     /db_xref="GeneID:433813"
                     /db_xref="MGI:MGI:3047787"
     exon            1..132
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..931
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /EC_number="5.4.99.-"
                     /note="tRNA-uridine isomerase-like 1; tRNA pseudouridylate
                     synthase-like 1"
                     /codon_start=1
                     /product="tRNA pseudouridine synthase-like 1"
                     /protein_id="NP_001028662.1"
                     /db_xref="CCDS:CCDS51404.1"
                     /db_xref="GeneID:433813"
                     /db_xref="MGI:MGI:3047787"
                     /translation="MGSCGAVGSVRARYLVFLQYLGTDFNGVAAVRGNPRAVGVLNFL
                     EEAAKRLNSVDPVRFTISSRTDAGVHALSNAAHLDIQRRPGQSPFSPEVVAKALNTHL
                     KHPAIRVLKAFRVPNDFHARHAATSRTYQYRLATGCSWPNQLPVFEQNVCWALQTEYL
                     DMAAMQEAAQHLLGTHDFSAFQSAGSPVTNTVRTLRRVSVSPGPASPFVLPEGSRRLQ
                     FWTLEFESQSFLYRQVRRMTAVLVAVGLGILAPTQVKVILESQDPLGKYQARVAPARG
                     LFLKSVLYDNFGPTS"
     exon            133..190
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            191..378
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            379..528
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            529..699
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            700..754
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            755..917
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1229
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1206..1211
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1229
                     /gene="Pusl1"
                     /gene_synonym="2810021I11Rik"
                     /note="major polyA site"
ORIGIN      
        1 ccctgctggg ctgggtcgac cgcgggccac gtgcaagcgc cccgcccgct caaatatggg
       61 ctcctgcggg gcggtgggct cggtgcgtgc gcgctacctt gtgttcttgc agtacttggg
      121 cactgacttc aatggggttg cggccgtgag gggcaatccg cgcgctgttg gggtgctgaa
      181 cttcctggag gaggctgcca agcggctgaa ctctgtcgac ccggtcaggt tcaccatctc
      241 tagccgcacc gatgccgggg tgcatgccct gagcaacgcg gcgcacctgg acatccagcg
      301 ccgcccaggg cagtcgcctt tctccccgga ggtcgtggcc aaggccctca acacccacct
      361 gaagcacccg gccattcgtg tactgaaggc cttccgagtg cccaacgact tccacgctcg
      421 acacgcagcc acctccagga cctaccaata tcgtctggcc acaggctgct cctggcctaa
      481 tcaactgcct gtgtttgaac aaaatgtatg ctgggctctg cagacagagt acctggatat
      541 ggcggccatg caggaggctg cccagcacct cctcgggaca catgatttta gtgccttcca
      601 gtctgctggc agcccagtca caaatactgt acgcacactt cgaagagtct cagtgtcacc
      661 tggtccagcc agcccatttg tcctccccga ggggagcagg aggctgcagt tctggacctt
      721 ggagtttgag agccagtctt tcctttatag acaggtgcgg aggatgacag ctgtgttggt
      781 ggctgtgggg ctagggatcc tggcacccac acaagtgaaa gtgattctgg agagtcaaga
      841 tcccttgggc aagtatcagg ctcgagttgc tccagcccgt ggcctgttct tgaagtcagt
      901 gctgtatgac aactttggtc ctacatcctg aaccctatgg tgtccgcggt gtggaaacta
      961 gatgacggta cacagtggag atgaagtgga gattgtacaa catttattgt gctcggcaga
     1021 gattaatcta cagctatgta gggctctggc agtcctgcct accttccagc agctaccact
     1081 tccccgggct ctctaccctg gacatccctt tgtcactaaa gggaacaaca tggggtacca
     1141 ggcagtcaaa agctgtaaaa accccatttt tctgggaacc ctgttttctt ggggcagaga
     1201 gtaggaataa aagacataga gaacaaaaa
//
