LOCUS       NM_026108               1044 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus pseudouridine 5'-phosphatase (Pudp), mRNA.
ACCESSION   NM_026108
VERSION     NM_026108.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1044)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN834894.1 and AK014922.1.
            
            On Jan 19, 2008 this sequence version replaced NM_026108.2.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                CN834894.1         4-86
            84-1044             AK014922.1         61-1021
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 27.32 cM"
     gene            1..1044
                     /gene="Pudp"
                     /gene_synonym="1700121L12Rik; GS1; Hdhd1; Hdhd1a"
                     /note="pseudouridine 5'-phosphatase"
                     /db_xref="GeneID:67365"
                     /db_xref="MGI:MGI:1914615"
     exon            1..1044
                     /gene="Pudp"
                     /gene_synonym="1700121L12Rik; GS1; Hdhd1; Hdhd1a"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..744
                     /gene="Pudp"
                     /gene_synonym="1700121L12Rik; GS1; Hdhd1; Hdhd1a"
                     /EC_number="3.1.3.96"
                     /note="haloacid dehalogenase-like hydrolase
                     domain-containing protein 1; haloacid dehalogenase-like
                     hydrolase domain-containing protein 1A;
                     pseudouridine-5'-monophosphatase; 5'-PsiMPase; haloacid
                     dehalogenase-like hydrolase domain containing 1A;
                     pseudouridine 5-phosphatase"
                     /codon_start=1
                     /product="pseudouridine-5'-phosphatase"
                     /protein_id="NP_080384.2"
                     /db_xref="CCDS:CCDS29244.1"
                     /db_xref="GeneID:67365"
                     /db_xref="MGI:MGI:1914615"
                     /translation="MAAAVPVPQFRPVTHLIFDLDGLILNTEDLYTDVFEEICNRYGK
                     KYNWDVKSLVMGKKALETAQTIVEFLNLPISKEELLKESQEKLQMVLHTAGFMPGAEE
                     LIHHLKKHRLPFALATSSETVTFQTKTSRHTGFFGLFHHIVLGDDPEVKNGKPGMDIF
                     LTCAKRFSPPPDPKDCLVFEDSPNGVEAAIHCGMQVVMVPHENLSADLTRKATLVLSS
                     LHDFKPELFGLPAFTE"
     regulatory      872..877
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pudp"
                     /gene_synonym="1700121L12Rik; GS1; Hdhd1; Hdhd1a"
                     /note="hexamer: TATAAA"
     polyA_site      897
                     /gene="Pudp"
                     /gene_synonym="1700121L12Rik; GS1; Hdhd1; Hdhd1a"
                     /note="major polyA site"
     regulatory      982..987
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Pudp"
                     /gene_synonym="1700121L12Rik; GS1; Hdhd1; Hdhd1a"
                     /note="hexamer: AGTAAA"
     polyA_site      1008
                     /gene="Pudp"
                     /gene_synonym="1700121L12Rik; GS1; Hdhd1; Hdhd1a"
ORIGIN      
        1 gctcctcttt tgaccctgtc cctgtccacc actactatta tggcggcggc agttcctgtg
       61 ccccaatttc gaccagttac acacctgata tttgacctgg acggacttat tctgaatact
      121 gaagatttat ataccgatgt gtttgaagaa atatgcaatc gctatgggaa gaaatacaac
      181 tgggatgtta agtccctggt catggggaag aaggctctag aaaccgcaca gaccatagta
      241 gagttcctca atttacccat atccaaagaa gaactattga aagaaagtca ggagaagctg
      301 cagatggtgt tgcacacagc tggattcatg ccaggagctg aggaattgat ccaccacctg
      361 aagaaacacc gcttaccctt tgccctggcc accagctccg agaccgttac cttccaaaca
      421 aagaccagta gacacacagg attctttggt ctatttcacc acatcgttct gggggatgat
      481 cctgaagtaa agaatggcaa gccaggcatg gacatatttc taacctgtgc caagaggttc
      541 tctcctcccc ctgatccaaa agactgcctc gtctttgaag attctccaaa tggagtggag
      601 gcagccatcc actgtgggat gcaggtcgtc atggtacctc atgaaaacct gagcgcagac
      661 ctaacacgaa aagccaccct ggtgctgagt tccctccacg acttcaagcc tgaactgttt
      721 ggtctacctg cctttacgga ataagggtga agggtgacgg tgctgctgtg ggcctcatgt
      781 aacccaaagt tggctcagga cccatgttgc tgagtggaaa cattaggaaa tcaacatcat
      841 ccaaattgta acctttcttg tcactgtagg ttataaagtc atgggttcca ttatgtattc
      901 agtctcctct gtgatttgct ctacatttga cagtagaaag aaaaccagag cttagactgg
      961 ccatctacag ttactatcta aagtaaagct gacttgggat acagtaaagg aagtgtacat
     1021 gcatgtttaa atacacgtga atat
//
