LOCUS       NM_026747               1582 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus pentraxin 4 (Ptx4), transcript variant 1, mRNA.
ACCESSION   NM_026747
VERSION     NM_026747.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1582)
  AUTHORS   Martinez de la Torre,Y., Fabbri,M., Jaillon,S., Bastone,A.,
            Nebuloni,M., Vecchi,A., Mantovani,A. and Garlanda,C.
  TITLE     Evolution of the pentraxin family: the new entry PTX4
  JOURNAL   J Immunol 184 (9), 5055-5064 (2010)
   PUBMED   20357257
  REMARK    GeneRIF: The long pentraxin Ptx4 discovered in this study reveals
            that the gene clusters alone in phylogenetic analysis, is well
            conserved from mammals to lower vertebrates and has a unique
            pattern of messenger RNA expression.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130711.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107381.2, SRR10662772.4209733.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-232               AC130711.3         107759-107990
            233-887             AC130711.3         109693-110347
            888-1582            AC130711.3         111573-112267
FEATURES             Location/Qualifiers
     source          1..1582
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.53 cM"
     gene            1..1582
                     /gene="Ptx4"
                     /gene_synonym="1110018H23Rik"
                     /note="pentraxin 4"
                     /db_xref="GeneID:68509"
                     /db_xref="MGI:MGI:1915759"
     exon            1..232
                     /gene="Ptx4"
                     /gene_synonym="1110018H23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..1540
                     /gene="Ptx4"
                     /gene_synonym="1110018H23Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; neuronal pentraxin-like protein C16orf38
                     homolog"
                     /codon_start=1
                     /product="pentraxin-4 isoform 1 precursor"
                     /protein_id="NP_081023.1"
                     /db_xref="CCDS:CCDS50031.1"
                     /db_xref="GeneID:68509"
                     /db_xref="MGI:MGI:1915759"
                     /translation="MRCLKKKTLLFLLIFVSLNVHRTPSQEAHPARQRKPFFERLRRL
                     EEQFQRFQQVTLTHLQNIANNYNVYHNMDVRFQSLVEQSQAVALAMNQSQAAIQGDVA
                     HLKTWYRKSQRRSQKVDARLQALDLSLSTKSRQWVEKEGEQKAQREAIASLALSVQAL
                     QDALASLTQQVHSQGARLAALEGQTQRASSGTVALGLTTAPNPTQLAQRGPGSLQLWR
                     DRQVAKSSPQHRSSPHDVTVHVQEMQKFQTPSSHQAAPPRTYQGPGNICNTDPVLIFP
                     NTSTENVIFLSPGFLMPLRALSFCSWVRMATSHLGTLLSYATKDNDNKLVLHGRNSLV
                     PGSIHFVIGDPDFRELSLKPLLDGQWHHICIIWTSVEGKYWLHIDRRLVATGSRFREG
                     YEIPPGGSLVLGQEQDTVGGEFDSSEAFVGSISGLAIWDRALLPREVANLASGKELPT
                     GAILTLTNVTSVGGFVQRAKCTCLEQCPYATP"
     exon            233..887
                     /gene="Ptx4"
                     /gene_synonym="1110018H23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1582
                     /gene="Ptx4"
                     /gene_synonym="1110018H23Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtcacatgg tgggcttcaa ggagcaggga tacgagacag actcaaggga ccaagggacg
       61 aacatcagct tctgcctctg tgtgtcccag catgaggtgc ttgaagaaga agaccctgct
      121 ttttctcctc atttttgtgt ccctgaatgt acacaggact ccgtcacagg aagctcaccc
      181 agccaggcaa agaaagccat tttttgagag gctccgtcga ctagaagagc agtttcagag
      241 attccaacag gtgaccttaa cacaccttca gaacattgcc aacaactaca atgtttacca
      301 caatatggat gttcgcttcc agagcctggt ggaacagagc caagccgtag ctctagcgat
      361 gaatcagtct caagctgcca tacaaggaga tgtggcccat ttaaagacct ggtataggaa
      421 gagccagcga aggagccaga aggtagatgc ccgacttcaa gccttggacc tctccctgag
      481 cacaaagagc aggcagtggg tagagaagga aggggagcaa aaggcacaga gggaggctat
      541 tgcaagcctg gccctaagcg ttcaggcact acaggatgca ctggccagcc ttacacagca
      601 agtccacagc cagggtgcca ggcttgctgc tctggaggga cagacacaga gggcctcctc
      661 tggtactgtg gccctggggt tgaccacagc ccccaacccc acccagcttg ctcagcgagg
      721 cccaggatcc ttgcaactgt ggagggaccg ccaggtagcc aagtcttcac cccaacacag
      781 gagttcccct catgacgtca ctgtccacgt tcaggagatg cagaagttcc aaaccccaag
      841 cagtcatcaa gcagccccac caaggaccta ccaaggacca ggaaacattt gcaacacgga
      901 cccagtgctg attttcccca acacctccac cgaaaatgtg atcttcctta gccctggctt
      961 cctcatgccc ctacgagccc tgtccttctg cagttgggtc cgaatggcca ccagccacct
     1021 gggcaccctc ctttcctatg ccaccaaaga caatgacaac aagttagtac tgcatggccg
     1081 aaactccctg gtccctggtt ccatccactt tgtgattggg gacccagact tcagggaact
     1141 gtccctgaaa ccactcctgg atggccagtg gcaccacatt tgtatcatct ggacatccgt
     1201 ggagggcaag tactggctcc acatagaccg aaggttagta gccaccggct cccgcttcag
     1261 agagggctat gagatccctc ccggagggtc gcttgtgctg ggccaggaac aagacactgt
     1321 ggggggcgag tttgacagct ctgaggcctt cgtagggagc atatctggct tggccatctg
     1381 ggaccgggca ctgctcccta gagaagttgc aaacttggcc tctggaaaag agctcccaac
     1441 aggcgctatt ctgacgctga ccaatgtcac ttctgtgggt ggatttgtgc agagagccaa
     1501 atgtacctgc ctggagcagt gtccatatgc cacaccgtga ctgtgtcaca cacagtcaag
     1561 gccatcaaga acaagcctca cc
//
