LOCUS       NM_001370987            9972 bp    mRNA    linear   ROD 16-FEB-2025
DEFINITION  Mus musculus protein tyrosine phosphatase receptor type Q (Ptprq),
            transcript variant 1, mRNA.
ACCESSION   NM_001370987 XM_017313939
VERSION     NM_001370987.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9972)
  AUTHORS   Qi,J., Tan,F., Zhang,L., Zhou,Y., Zhang,Z., Sun,Q., Li,N., Fang,Y.,
            Chen,X., Wu,Y., Zhong,G. and Chai,R.
  TITLE     Critical role of TPRN rings in the stereocilia for hearing
  JOURNAL   Mol Ther 32 (1), 204-217 (2024)
   PUBMED   37952086
  REMARK    Erratum:[Mol Ther. 2025 Jan 8;33(1):419-420. doi:
            10.1016/j.ymthe.2024.12.004.. PMID: 39672160]
REFERENCE   2  (bases 1 to 9972)
  AUTHORS   Wagner,E.L., Im,J.S., Sala,S., Nakahata,M.I., Imbery,T.E., Li,S.,
            Chen,D., Nimchuk,K., Noy,Y., Archer,D.W., Xu,W., Hashisaki,G.,
            Avraham,K.B., Oakes,P.W. and Shin,J.B.
  TITLE     Repair of noise-induced damage to stereocilia F-actin cores is
            facilitated by XIRP2 and its novel mechanosensor domain
  JOURNAL   Elife 12, e72681 (2023)
   PUBMED   37294664
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9972)
  AUTHORS   Krey,J.F., Dumont,R.A., Wilmarth,P.A., David,L.L., Johnson,K.R. and
            Barr-Gillespie,P.G.
  TITLE     ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical
            Structures in Developing Vestibular Hair Cells
  JOURNAL   J Neurosci 38 (4), 843-857 (2018)
   PUBMED   29222402
REFERENCE   4  (bases 1 to 9972)
  AUTHORS   Potter,P.K., Bowl,M.R., Jeyarajan,P., Wisby,L., Blease,A.,
            Goldsworthy,M.E., Simon,M.M., Greenaway,S., Michel,V., Barnard,A.,
            Aguilar,C., Agnew,T., Banks,G., Blake,A., Chessum,L., Dorning,J.,
            Falcone,S., Goosey,L., Harris,S., Haynes,A., Heise,I., Hillier,R.,
            Hough,T., Hoslin,A., Hutchison,M., King,R., Kumar,S., Lad,H.V.,
            Law,G., MacLaren,R.E., Morse,S., Nicol,T., Parker,A., Pickford,K.,
            Sethi,S., Starbuck,B., Stelma,F., Cheeseman,M., Cross,S.H.,
            Foster,R.G., Jackson,I.J., Peirson,S.N., Thakker,R.V., Vincent,T.,
            Scudamore,C., Wells,S., El-Amraoui,A., Petit,C.,
            Acevedo-Arozena,A., Nolan,P.M., Cox,R., Mallon,A.M. and Brown,S.D.
  TITLE     Novel gene function revealed by mouse mutagenesis screens for
            models of age-related disease
  JOURNAL   Nat Commun 7, 12444 (2016)
   PUBMED   27534441
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9972)
  AUTHORS   Chen,J., Johnson,S.L., Lewis,M.A., Hilton,J.M., Huma,A.,
            Marcotti,W. and Steel,K.P.
  TITLE     A reduction in Ptprq associated with specific features of the
            deafness phenotype of the miR-96 mutant mouse diminuendo
  JOURNAL   Eur J Neurosci 39 (5), 744-756 (2014)
   PUBMED   24446963
  REMARK    GeneRIF: The reduction in Ptprq observed in miR-96 mutantdiminuendo
            mice appears to be a major contributor to the morphological,
            transcriptional and electrophysiological phenotype
REFERENCE   6  (bases 1 to 9972)
  AUTHORS   Goodyear,R.J., Legan,P.K., Wright,M.B., Marcotti,W., Oganesian,A.,
            Coats,S.A., Booth,C.J., Kros,C.J., Seifert,R.A., Bowen-Pope,D.F.
            and Richardson,G.P.
  TITLE     A receptor-like inositol lipid phosphatase is required for the
            maturation of developing cochlear hair bundles
  JOURNAL   J Neurosci 23 (27), 9208-9219 (2003)
   PUBMED   14534255
  REMARK    GeneRIF: Ptprq is required for formation of the shaft connectors of
            the hair bundle, the normal maturation of cochlear hair bundles,
            and the long-term survival of high-frequency auditory hair cells
REFERENCE   7  (bases 1 to 9972)
  AUTHORS   Oganesian,A., Poot,M., Daum,G., Coats,S.A., Wright,M.B.,
            Seifert,R.A. and Bowen-Pope,D.F.
  TITLE     Protein tyrosine phosphatase RQ is a phosphatidylinositol
            phosphatase that can regulate cell survival and proliferation
  JOURNAL   Proc Natl Acad Sci U S A 100 (13), 7563-7568 (2003)
   PUBMED   12802008
REFERENCE   8  (bases 1 to 9972)
  AUTHORS   Carvajal,J.J., Cox,D., Summerbell,D. and Rigby,P.W.
  TITLE     A BAC transgenic analysis of the Mrf4/Myf5 locus reveals
            interdigitated elements that control activation and maintenance of
            gene expression during muscle development
  JOURNAL   Development 128 (10), 1857-1868 (2001)
   PUBMED   11311165
REFERENCE   9  (bases 1 to 9972)
  AUTHORS   Wright,M.B., Hugo,C., Seifert,R., Disteche,C.M. and Bowen-Pope,D.F.
  TITLE     Proliferating and migrating mesangial cells responding to injury
            express a novel receptor protein-tyrosine phosphatase in
            experimental mesangial proliferative glomerulonephritis
  JOURNAL   J Biol Chem 273 (37), 23929-23937 (1998)
   PUBMED   9727007
REFERENCE   10 (bases 1 to 9972)
  AUTHORS   Hendriks,W., Schepens,J., Brugman,C., Zeeuwen,P. and Wieringa,B.
  TITLE     A novel receptor-type protein tyrosine phosphatase with a single
            catalytic domain is specifically expressed in mouse brain
  JOURNAL   Biochem J 305 (Pt 2) (Pt 2), 499-504 (1995)
   PUBMED   7832766
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123948.4, AC021642.14 and AC155168.3.
            
            On Jun 20, 2019 this sequence version replaced XM_017313939.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849374, SAMN00849375
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-123               AC123948.4         82915-83037         c
            124-235             AC123948.4         82464-82575         c
            236-462             AC123948.4         81566-81792         c
            463-532             AC123948.4         79179-79248         c
            533-732             AC123948.4         74969-75168         c
            733-982             AC123948.4         73615-73864         c
            983-1111            AC123948.4         71722-71850         c
            1112-1258           AC123948.4         68571-68717         c
            1259-1431           AC123948.4         62637-62809         c
            1432-1609           AC123948.4         51427-51604         c
            1610-1774           AC123948.4         49585-49749         c
            1775-1954           AC123948.4         49303-49482         c
            1955-2062           AC123948.4         48630-48737         c
            2063-2344           AC123948.4         48134-48415         c
            2345-2527           AC123948.4         30437-30619         c
            2528-2629           AC123948.4         29595-29696         c
            2630-2750           AC123948.4         25633-25753         c
            2751-2911           AC123948.4         16520-16680         c
            2912-3057           AC123948.4         15686-15831         c
            3058-3226           AC123948.4         9653-9821           c
            3227-3520           AC021642.14        1573-1866
            3521-3796           AC021642.14        2110-2385
            3797-3948           AC021642.14        2770-2921
            3949-4090           AC021642.14        6860-7001
            4091-4360           AC021642.14        10306-10575
            4361-4684           AC021642.14        37373-37696
            4685-4806           AC021642.14        54766-54887
            4807-4993           AC021642.14        59031-59217
            4994-5238           AC021642.14        63234-63478
            5239-5305           AC021642.14        65557-65623
            5306-5464           AC021642.14        68823-68981
            5465-5687           AC021642.14        69715-69937
            5688-5761           AC021642.14        72791-72864
            5762-5861           AC021642.14        79886-79985
            5862-5990           AC021642.14        82563-82691
            5991-6017           AC021642.14        102408-102434
            6018-6099           AC021642.14        103093-103174
            6100-6190           AC021642.14        106804-106894
            6191-6267           AC021642.14        111116-111192
            6268-6402           AC021642.14        119682-119816
            6403-6528           AC021642.14        120008-120133
            6529-6677           AC021642.14        121470-121618
            6678-6813           AC021642.14        122191-122326
            6814-6937           AC155168.3         172385-172508       c
            6938-9972           AC155168.3         168959-171993       c
FEATURES             Location/Qualifiers
     source          1..9972
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 55.97 cM"
     gene            1..9972
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /note="protein tyrosine phosphatase receptor type Q"
                     /db_xref="GeneID:237523"
                     /db_xref="MGI:MGI:1096349"
     exon            1..123
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..6975
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /EC_number="3.1.3.67"
                     /EC_number="3.1.3.36"
                     /EC_number="3.1.3.86"
                     /EC_number="3.1.3.95"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; phosphotidylinositol phosphatase PTPRQ;
                     phosphatidylinositol phosphatase PTPRQ"
                     /codon_start=1
                     /product="phosphatidylinositol phosphatase PTPRQ isoform 1
                     precursor"
                     /protein_id="NP_001357916.1"
                     /db_xref="GeneID:237523"
                     /db_xref="MGI:MGI:1096349"
                     /translation="MDFLFFFLFSLIGTSESQVDVSGSFDDTVYDITLSSISATTYSS
                     PVSRTLATNVSKPGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYVVKYKEVCPWMQ
                     TAYTRVRAKPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSDPFLFQTAESAPGKVV
                     NLTVEALNYSAVNLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSIKVEDLLSGKLP
                     ECNENSDSFLWSTTSPSPTLSRATPPLRTTHLSNTLARNKISSVWKEPISFVVTHLRP
                     YTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCITGNVTGKAFSISWDPPAIVT
                     GKFSYRVELYGPTGRILDNSTKDLRFVFTHLTPFTMYDVYVAAETSAGVGPKSNLSVF
                     TPPDVPGAVFDLQIVEVEATEIRVSWRKPRQPNGIISQYRVKVSVLESGVILENTLLT
                     GQDEYINNPMTPEIMNLVDPMIGFYEGSGEMSSDLHSLASFIYNSHPHDFPARTRVED
                     QRSPVVVATRNQYMTDIAAEHLSYVIRRLVPFTEHTISVSAFTVMGEGPPTVLTVRTR
                     EQVPSSIQIINYKNISSSSILLYWDPPEYPNGKITHYTIYAMELDTNRAFQMTTVDNS
                     FLITGLKKYTRYKMRVAASTHVGESSLSEENDLFVRTPEDEPESSPQDVKVTDVSPSE
                     LSLTWSPPEKPNGIIIAYEVFYQNADALFVKNTSTTNITLSDLKPYTLYNISIQSYTR
                     LGHGNQSSSLLSVRTSETVPDSAPENITYKNISSEEIEIFFLPPRSPNGIIQKYTIYL
                     KRSNSHEARTIETTSLTLTIGGLKKYTHYVIEVSASTLKGEGVRSMPISILTEEDAPD
                     SPPQNFSVKQLSGVTVMLSWQPPLEPNGIILYYTVYVWDKVSLKTINATEVSLELSDL
                     DYHADYSAYVTASTRFGDGKTRSSVINFRTPEGEPSDPPKDVHYVNLSSSSIILFWTP
                     PVKPNGIIQYYSVYYQNTSSTFVQNFTLLEVTQEPGNVTVSARIYKLAVFSYYTFWLT
                     ASTLVGNGNKSSDVIHVYTDQDIPEGGVGNLTYESLSSTAINVSWTPPSQPNGLVFYY
                     VSLNLQQSPPRHRRPPLTTYENSIYFDNLEKYTDYIFKITPSTEKGFSETYTAQLHIK
                     TEEDVPDTPPIINTFKNLSSTSILLSWDPPLKPNGAILSYHLTLQGTHANRTFVTSGN
                     HIVLEELSPFTLYSFLAAARTMKGLGPSSILFFYTDESAPLAPPQNLTLINYTSDFVW
                     LTWSPSPLPGGIVKVYSFKIHEHETDTVFYKNISGFQTDAKLAGLEPVSTYSISVSAF
                     TKVGNGNQFSNVVKFTTQESVPDAVQNIACVARDWQSVSVMWDPPRKANGIIIHYMIT
                     VEGNSTKVSPRDPMYTFTKLLANTSYIFEVRASTSAGEGNESQCNVSTLPETVPSVPT
                     NTAFSNVQSTSVTLRWIKPDTILGYFQNYKITTQLRAQKCREWEPEECVEHQEVQYLY
                     EANQTEDTVRGLKKFQWYRFQVAASTNAGYGNASSWISTQTLPGPPDGPPENVRVVAT
                     SPFGINISWNEPAIITGPTFYLIDVKSVDNDNFNISFVKSNEENKTTEINDLEVFTRY
                     SVVITAFVGNVSGAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIPDEVTKFQLSFLP
                     PSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTDTSVIAMLEGLKGGHTYNISVYA
                     INSAGAGPKVQMRITMDIKAPARPKTKPIPIHDATGKLLVTSTTITIRMPICYYNDDH
                     GPIRNVQVLVAEAGAQQDGNVTKWYDAYFNKARPYFTNEGFPNPPCIEGKTKFSGNEE
                     IYVIGADNACMIPGNEEKICNGPLKPKKQYLFKFRATNVMGQFTDSEYSDPIKTLGEG
                     LSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTYSPRDAEIIDTKFKLDQ
                     LITVADLELKDERLTRLLSYRKSIKPVSKKSFLQHVEELCTNNNLKFQEEFSELPKFL
                     QDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADVSIPGSDYINASYVSGYLCPNEF
                     IATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIL
                     ITKLMEDIQIDWTIRDLKIERHGDCMTVRQCNFTGWPEHGVPENTTPLIHFVKLVRTS
                     RAHDATPMVVHCSAGVGRTGVFIALDHLTQHIHDHDFVDIYGLVAELRSERMCMVQNL
                     AQYIFLHQCILDLLSNKGGHQPVCFVNYSTLQKMDSLDAMEGDVELEWEETTM"
     exon            124..235
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            236..462
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            463..532
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            533..732
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            733..982
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1111
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            1112..1258
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1431
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1609
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1774
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            1775..1954
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            1955..2062
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            2063..2344
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2527
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            2528..2629
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            2630..2750
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2911
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            2912..3057
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            3058..3226
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            3227..3520
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            3521..3796
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            3797..3948
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            3949..4090
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            4091..4360
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            4361..4684
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            4685..4806
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            4807..4993
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            4994..5238
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            5239..5305
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            5306..5464
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            5465..5687
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            5688..5761
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            5762..5861
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            5862..5990
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            5991..6017
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            6018..6099
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            6100..6190
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            6191..6267
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            6268..6402
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            6403..6528
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            6529..6677
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            6678..6813
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            6814..6937
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     exon            6938..9972
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7261..7266
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /note="hexamer: TATAAA"
     polyA_site      7287
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
     regulatory      7827..7832
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /note="hexamer: AATAAA"
     polyA_site      7850
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /note="major polyA site"
     regulatory      8735..8740
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /note="hexamer: AATAAA"
     polyA_site      8753
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
     regulatory      9533..9538
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /note="hexamer: ATTAAA"
     polyA_site      9560
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
     regulatory      9950..9955
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
                     /note="hexamer: AATAAA"
     polyA_site      9972
                     /gene="Ptprq"
                     /gene_synonym="R-PTP-Q"
ORIGIN      
        1 attaatgcag gcaacatttc tctctagagc catcaatgtg attgtactgc tagaaaaaat
       61 gtaataacga tggattttct tttctttttt cttttctctc tcattggaac ttcagagtca
      121 caggttgatg tttctggttc ttttgatgac actgtgtatg atatcacgct gtcttcaatt
      181 tctgccacaa cctacagctc acccgtgagt agaacactgg caacaaatgt gtcaaaaccg
      241 gggcctccag tcttcctagc cggggagaga gttggctctg ccgggattct cctttcatgg
      301 aatacccctc ctaacccaaa tggaagaatc atatcgtatg ttgttaaata caaggaagtg
      361 tgtccatgga tgcagacagc gtatacccga gtgagagcga agcccgacag tctggaggtc
      421 cttctcacta accttaaccc tggaacaaca tacgagatta aggttgctgc cgaaaacagc
      481 gctggcattg gagtgtttag tgacccattt ctttttcaaa ccgcagaaag tgctccaggg
      541 aaagtggtta acctcacagt ggaggccctc aactattctg cagtaaactt gatttggtat
      601 ttacctcggc aaccaaatgg taaaatcacc agcttcaaga tcagtgtcaa acacgccaga
      661 agcggtatag tagtgaagga tgtctccatc aaagtagagg accttttatc tgggaaatta
      721 cctgaatgta atgagaacag tgactctttt ctgtggagta ccaccagccc ctctccaacc
      781 ctcagtagag ccacacctcc acttcgtact acacatttat ccaacacatt ggcacggaat
      841 aagatcagct ctgtgtggaa agagcccatc agctttgtgg tgactcactt gagaccatac
      901 acaacgtatc tctttgaagt ttcagccgtt acgacggaag cagggtatat tgacagtacc
      961 attgttagga caccagaatc agtgcctgaa ggaccacccc agaactgtat aacaggcaat
     1021 gtcacaggaa aggcgttttc aatttcatgg gacccaccag caattgtcac aggaaagttt
     1081 agttacagag ttgaattata tgggccaaca ggaaggattt tggataatag tacaaaagac
     1141 ctccggtttg tgtttacgca tctcacgcca ttcacaatgt atgatgtcta tgttgctgca
     1201 gaaaccagtg ctggggttgg acccaagtca aatctttcag tattcactcc cccagatgtt
     1261 ccaggagcag tgtttgattt acagatcgtg gaggtagaag ccacagaaat aagagtttct
     1321 tggaggaaac ctcgacaacc aaatggaatc atcagccagt accgtgtaaa agtgtcagtc
     1381 ctagagtcag gagtcatttt ggaaaacact ctgctcacag gacaagatga gtatataaac
     1441 aaccccatga ctccagaaat aatgaaccta gtagacccaa tgataggatt ctatgagggc
     1501 tcaggagaga tgtcttcaga cctgcactcc ctggcttcgt tcatatacaa cagccatcca
     1561 cacgactttc ctgccaggac aagagttgaa gaccaaagat caccagttgt agtggccacc
     1621 aggaatcagt atatgactga cattgctgct gaacacctgt cttatgttat caggcggctt
     1681 gtacccttca ctgagcacac gattagcgta tctgctttca ctgtcatggg cgaaggacca
     1741 ccaacagttc tcactgttag gacacgtgag caagtgccaa gctccatcca aattataaac
     1801 tataaaaata ttagttcttc atctattttg ctatattggg atcctccaga atatcccaat
     1861 gggaaaatca ctcattatac aatctatgca atggaactgg atacaaacag agccttccag
     1921 atgactactg tagataacag ctttctcatc acagggttga agaaatatac aagatataaa
     1981 atgagggttg ctgcctcaac tcatgttggg gaaagttctc tgtcagaaga aaatgacctc
     2041 tttgtgagaa ctccagaaga tgagccagaa tcatcacctc aagatgtcaa agtaactgat
     2101 gtgtctccaa gtgaactgag cttgacctgg tccccacctg agaaacctaa tgggatcatt
     2161 attgcctacg aggtgtttta ccaaaatgca gatgccttgt ttgtaaagaa cacctccacc
     2221 acgaacataa ctttaagtga cctgaaacct tacacactct ataatatttc tatccagtca
     2281 tacaccagac ttggtcatgg caatcagtca tcctcattac tttctgtaag gacttcagag
     2341 actgtacctg atagtgcgcc agaaaatatt acttacaaaa acatttcctc ggaagagatt
     2401 gagattttct tccttcctcc aaggagtccc aatggcatca tacaaaagta cacgatttac
     2461 ctcaagagaa gtaatagcca cgaggcgaga actatagaaa caacctctct cactctcact
     2521 atcggaggac tgaagaagta tacccattat gtgattgagg tgtctgccag tacactgaaa
     2581 ggtgaaggag ttcggagtat gccaataagc atactgactg aggaagacgc tcctgactct
     2641 cctcctcaga acttctccgt gaaacagttg tctggtgtca ccgtgatgtt gtcatggcaa
     2701 ccacccttgg agccaaatgg aattatcctc tattacacag tttatgtctg ggataaagta
     2761 tcattaaaaa ctattaatgc aactgaagta tcactggagt tatccgactt agactatcat
     2821 gctgactata gcgcctatgt aacagctagc actagatttg gtgatgggaa aacaagaagc
     2881 agcgtcatta acttccgaac accagaggga gagcccagtg atcctcccaa agatgtccac
     2941 tatgtgaacc tcagttcttc atcgataatt ctcttttgga ctcctcctgt aaaacctaat
     3001 ggaatcatac aatattattc tgtttattac caaaatactt caagtacttt tgtgcagaat
     3061 tttacacttc tcgaagtaac ccaggagcct ggcaatgtga cagtgtctgc aagaatctat
     3121 aaactggcag tattcagcta ctatacattt tggctaacag caagtacttt agttggaaat
     3181 gggaataaaa gcagtgatgt aattcatgtc tacacagacc aagacatacc tgaaggtggt
     3241 gttggaaacc tgacttacga gtccctttca tcaactgcaa taaacgtgag ctggacgcca
     3301 ccatctcaac caaatggcct cgtcttctac tacgtttccc tgaatttaca gcagagcccc
     3361 ccgcggcaca ggagaccacc gctgactaca tatgaaaaca gcatatattt tgataatctg
     3421 gaaaaatata ctgactatat atttaaaatc actccatcaa cagaaaaggg attctctgag
     3481 acctatactg cccagctaca catcaaaact gaagaagatg ttccagacac tccaccaata
     3541 atcaacactt ttaaaaatct ttcttctacc tccattctct tatcgtggga tcccccatta
     3601 aagccaaacg gtgcaatcct aagttaccat ttaactttac aaggaaccca cgccaaccgc
     3661 actttcgtca cttccggtaa ccacatagta ctggaagaac tctcgccatt tactttatat
     3721 agttttttgg ctgcggcaag aactatgaaa ggacttggtc cttccagtat tcttttcttt
     3781 tacacagatg agtcagcgcc tttagcacct ccccagaatt tgactttaat caactacact
     3841 tcagatttcg tatggctgac gtggagtcca agccctcttc cgggcggtat tgttaaagtg
     3901 tatagtttta aaattcatga gcatgagact gatactgtat tttataagaa tatttcaggt
     3961 tttcagactg atgccaaact tgctggactg gagcctgtga gcacctactc aattagtgtg
     4021 tctgccttta ccaaagttgg aaatggcaat cagttcagta atgtggtgaa atttacaacc
     4081 caggagtctg ttccagatgc tgtacagaat attgcatgtg tggcacgtga ctggcagtca
     4141 gtatcagtga tgtgggaccc accaagaaaa gcaaatggaa taattattca ctatatgata
     4201 acagttgaag ggaattctac caaagtctcc cccagagacc ccatgtacac tttcacaaaa
     4261 cttcttgcca atacatcata catctttgaa gtaagagcgt caacctcagc tggtgaaggc
     4321 aatgaaagcc aatgtaatgt cagcacactc cctgagacag ttcccagtgt tcccacgaat
     4381 acagcatttt ctaatgtcca gtcaactagt gtaacactaa gatggataaa acctgatact
     4441 atccttggat acttccaaaa ttacaagata actactcagc ttcgtgctca gaagtgcaga
     4501 gaatgggagc ctgaggaatg tgttgaacat caggaagttc aatacctcta tgaagcaaac
     4561 caaacagaag acaccgtgcg tggattaaag aagtttcaat ggtacagatt ccaagtggct
     4621 gctagcacca acgctgggta cggcaatgcc tccagctgga tttccacaca aacgctgcct
     4681 ggccctcccg acggtcctcc tgaaaatgtt cgcgtggttg cgacatcccc ctttggtatc
     4741 aatatcagct ggaatgaacc tgccatcata actggaccaa ccttctacct gattgatgtc
     4801 aaatcggtag ataatgataa ctttaatatt tccttcgtga agtcaaatga agaaaacaaa
     4861 accacagaga ttaatgactt agaagtattc acaaggtatt ctgtggtgat caccgctttt
     4921 gttggaaatg ttagtggggc atacacagat gggaagtcaa gtgcagaagt gatcattacg
     4981 actttagaat cagtgcccaa ggatccacct aataatatga catttcagaa gataccggat
     5041 gaagtaacca agtttcagtt atcattcctc ccgccttctc agcccaacgg caatatccaa
     5101 gtgtatcaag cattggttta ccgagaagac gatcctactg ccgtccagat tcataacctc
     5161 agcattatcc agaagacaga cacgtccgtc attgcaatgc tcgaaggcct gaagggtgga
     5221 catacataca acatcagcgt ttatgctatc aacagtgctg gcgccggccc aaaagtgcag
     5281 atgcgaataa ccatggatat taaagctcca gcacgaccaa aaaccaagcc aattcctatt
     5341 catgatgcca caggaaaact gcttgtgacg tcaacaacaa ttacaatcag aatgccaatc
     5401 tgctactaca atgatgacca cgggccaatc agaaatgtgc aagtccttgt ggcagaagca
     5461 ggagctcagc aagacggaaa tgtgacaaag tggtatgatg catattttaa caaagcaagg
     5521 ccatatttta caaacgaagg attccctaat cccccgtgta tagagggaaa gactaagttc
     5581 agcggtaatg aagaaatcta tgtgataggt gctgataatg cctgcatgat ccctggaaat
     5641 gaggagaaaa tttgcaatgg acctctgaaa cccaaaaagc agtatttgtt taaatttaga
     5701 gccacaaatg tcatgggaca atttactgac tctgagtact ctgaccctat taaaacttta
     5761 ggtgaaggac tttcagaaag aaccgtggag atcatactgt cagtcacttt gtgtatcctc
     5821 tcaatcatcc tccttggaac agctattttt gcatttgcaa gaatcagaca gaagcagaag
     5881 gaaggtggta cgtactctcc tcgggacgca gagattattg acactaaatt caagctggat
     5941 cagctcatca cggtggcaga cttggagctg aaggacgaga gattaacgcg gttacttagt
     6001 tatagaaaat ccatcaagcc ggtaagcaag aaatccttcc tgcaacatgt tgaagagctt
     6061 tgcacaaaca acaacctaaa gtttcaagag gaattttcgg aattaccaaa atttcttcaa
     6121 gatctctcct caactgatgc tgatctccct tggaacagag caaaaaatcg ctttcccaac
     6181 ataaaaccat acaataataa cagagtgaag ctgatagctg atgtaagcat cccgggatca
     6241 gattacatta atgccagcta tgtttctgga tacttatgtc ccaatgagtt tattgccacc
     6301 caaggcccat taccgggaac agttggagac ttttggagaa tggtgtggga aaccagagcg
     6361 aaaacattgg taatgctcac acagtgtttt gagaaaggac ggatcagatg ccatcagtat
     6421 tggcccgagg acaacaagcc agtgacagtc tttggagaca tactgattac aaagcttatg
     6481 gaggacattc agatcgactg gaccatcagg gatctgaaaa ttgaaaggca tggagactgc
     6541 atgactgtca ggcagtgtaa cttcacgggt tggcctgagc atggggttcc tgaaaacacc
     6601 acccctctaa ttcactttgt gaagttggta cgaacaagca gagcacacga cgctacccct
     6661 atggttgtgc attgcagcgc tggggttgga aggacgggag ttttcattgc tctggaccac
     6721 ttaacacagc acatacatga ccatgacttt gtggacatat atggactagt agctgaactg
     6781 aggagtgaga gaatgtgcat ggtgcagaac ctggcacagt atatcttctt acaccagtgc
     6841 attctggatc ttttatcaaa taaaggagga catcagccgg tctgttttgt taactactcc
     6901 acacttcaga agatggactc tctggatgcc atggaaggtg atgtggaact tgaatgggaa
     6961 gaaactacca tgtaaaattt ggaccaaagt tacaaataga agacagaatt ttcagatccc
     7021 aggagccaaa atcatccctc ttgcttctga aatgaactgg gcaaaggaaa tcttcatgct
     7081 tcctagatgg tgcctcacta actgggttga tcggtttatg gacagatggt tgtaggaaaa
     7141 cagtcctata agatagttat ttgttttata tagaattaaa tattatgtat tttaaaatgt
     7201 ctaagaaaat acatcatgca agttttttga ggtccttaat tctttttgaa gtaagccaaa
     7261 tataaaatta ttattattat tctagcatac ctgtttcaga atacactttc cctttgtatt
     7321 ggatttcatt ttaaagaaaa gctgtagatg ttcatttggt agtgttattt tggcctccgg
     7381 ggtggtgctg atgtttctta tggacgactt ccaagactgt cataatgatc tgcacttcca
     7441 cgcatgcccc tggcttttga atcctctgtt ttatgagtgt caagatatca tctactgatc
     7501 ccgaacagct gagcagtaac ctcgtgacac tgcagagagt gctcagcctt tattccatgc
     7561 tcagtagctc tcggagacaa cgcaaggcta tttaaattgt actgtgatct tcagtttgca
     7621 aaaagtgaaa agaaaatttc aaagtacatc ctcacctatg aagttataga gcatctttct
     7681 cagctgccta cactggtaca ggcacaggtt gcacccacta tggtctcgaa aaacatagac
     7741 aagtgaatca gagtatttgt cagcttgatg tacattcaac actaatagtt ttgaagagtt
     7801 tctggatagc aatgtataaa aacggcaata aagccataca ttgtgttgca cgtgtgtaag
     7861 ctgatgaacg ccatgcttct gtggcgccaa caggaacttc cctgtagatg acaccactga
     7921 atagcctgac ttcgtacccg agggctgagt atacagaaga acactcagta taacttaaag
     7981 aaattaacaa ggctggaaca aataagacat tacaaaaata aactcatttt agctttcttt
     8041 tctctgtata aaagtgtatg aaattgtttt gtcacagagt caaaatcata ataacaaaat
     8101 agcattcatc atcctaattc tgtgataaga accatacctt gcactttatc aagctctaca
     8161 gacagaaaac ttgagagcta atgaaagtga atattaatga attgggttac cttgaagcat
     8221 gatttgaaat attaattaaa ctatatgtat atatgaagac atcagcaatt atattaatta
     8281 tagttattac atagtaacat aaaatctttt ctatattagt acaacataat tgcaatttat
     8341 atgtaattca cataaaatta tttctaaagg catccttaaa aattaatatt gatatggaaa
     8401 tgcagtatcc aagcaattaa atatgttatt ctaaaaagca gtaccaaaaa gttcaagatt
     8461 tgcatactat ttttttttac aaaaagcata tacaaatgaa tagtaactac aactccaacg
     8521 aacatgtttg tgctattatt gaaagttaca aaaagcaata acaattgagg agaagtctaa
     8581 aagtttcaac tttcagctaa acactctcta ttgaaaaatg tatggcaacc agcagggttt
     8641 ttgtgttcat ggagacagaa agtctatgaa aagtactgac tggatttact tttaaatata
     8701 gtaaataata atgatgatga tgatgatcac aataaataaa atatatagtt tgattcaaag
     8761 gctagatcat tgtctatgat atctgcaaaa tggattcatg agaatagttt tttctgggtt
     8821 gcccagagtg ttcacgtgtg aatatccata aagcactgaa taatattagc tttcttctaa
     8881 aatagctcta actgagctgt agctttttat taagtcacct gcagattatt ttaaaatgaa
     8941 agggtttctt cggtgaaaat aatagagccc tgagaatcac tttttactta tactccaagt
     9001 atatcactgt ttgatatcaa accatattct aaataattgt gaatctatag aagacattgg
     9061 gattagaata attttagatc tcccaaaaat tagtaaagat aactttcaaa aggatttgaa
     9121 tactttactg aaaacaatat gtaggttgtt atatctgcac agcttagtga tacattgaga
     9181 gatttttaac tgagagtaga tggatagata aacggtttcc taattatata gtgaaaggac
     9241 ccatgtaaat tgtagttcta caggtggcta ctaagtgcaa attaaaatga agaacacctg
     9301 tagctttttt agctccaatt tgtcaaagtt cattgaagca tttgtactat aaatggtcaa
     9361 catgtgtttc ataggaatca agtgaaactg gagcctctct gaatggttcg ccagagacca
     9421 gagcagctgc gggtagtgcc tctcctttca tgctgcactt aaatgcatac tttatttttt
     9481 ttctgttact gtataaggaa atgtacataa taagtctttt gcaaaaatac taattaaact
     9541 ttgacctcga cataaaagaa cgaaccgcat tccggaaaac tataccaaac ccttgaattt
     9601 taaaatggaa ttggtgttca gcagagggtt ctgtaagctc atgtttacag tcattaagat
     9661 aaccaagtct gtttacaagg tccttcagaa aattcagtcg tatttttaag agaattggaa
     9721 cacaaagtga cttgaattac tcaactaaat gatgctaatc attgaaactt gaacgttgtt
     9781 aaatattaac tcaacaaaat gcctatcttc ttaaaatgga gaatatttca ggataaatga
     9841 tttattcaat atggacagtt tccaggtaga atattgtcta gtatatctac ttgtggagat
     9901 aatctaaata acacttatga ttacatacat gaaaggtttt gaaaaataaa ataaacttta
     9961 tatggttaga aa
//
