LOCUS       NM_011213               7648 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus protein tyrosine phosphatase receptor type F (Ptprf),
            mRNA.
ACCESSION   NM_011213
VERSION     NM_011213.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7648)
  AUTHORS   Emperador-Melero,J., Andersen,J.W., Metzbower,S.R., Levy,A.D.,
            Dharmasri,P.A., de Nola,G., Blanpied,T.A. and Kaeser,P.S.
  TITLE     Distinct active zone protein machineries mediate Ca2+ channel
            clustering and vesicle priming at hippocampal synapses
  JOURNAL   Nat Neurosci 27 (9), 1680-1694 (2024)
   PUBMED   39160372
REFERENCE   2  (bases 1 to 7648)
  AUTHORS   Wang,J., Ma,Y., Li,T., Li,J., Yang,X., Hua,G., Cai,G., Zhang,H.,
            Liu,Z., Wu,K. and Deng,X.
  TITLE     MiR-199a-3p Regulates the PTPRF/beta-Catenin Axis in Hair Follicle
            Development: Insights into the Pathogenic Mechanism of Alopecia
            Areata
  JOURNAL   Int J Mol Sci 24 (24), 17632 (2023)
   PUBMED   38139460
  REMARK    GeneRIF: MiR-199a-3p Regulates the PTPRF/beta-Catenin Axis in Hair
            Follicle Development: Insights into the Pathogenic Mechanism of
            Alopecia Areata.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7648)
  AUTHORS   Sclip,A. and Sudhof,T.C.
  TITLE     Combinatorial expression of neurexins and LAR-type phosphotyrosine
            phosphatase receptors instructs assembly of a cerebellar circuit
  JOURNAL   Nat Commun 14 (1), 4976 (2023)
   PUBMED   37591863
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7648)
  AUTHORS   Schaberg,E., Theocharidis,U., May,M., Lessmann,K., Schroeder,T. and
            Faissner,A.
  TITLE     Sulfation of Glycosaminoglycans Modulates the Cell Cycle of
            Embryonic Mouse Spinal Cord Neural Stem Cells
  JOURNAL   Front Cell Dev Biol 9, 643060 (2021)
   PUBMED   34169071
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7648)
  AUTHORS   Emperador-Melero,J., de Nola,G. and Kaeser,P.S.
  TITLE     Intact synapse structure and function after combined knockout of
            PTPdelta, PTPsigma, and LAR
  JOURNAL   Elife 10, e66638 (2021)
   PUBMED   33656439
  REMARK    GeneRIF: Intact synapse structure and function after combined
            knockout of PTPdelta, PTPsigma, and LAR.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7648)
  AUTHORS   Skarnes,W.C., Moss,J.E., Hurtley,S.M. and Beddington,R.S.
  TITLE     Capturing genes encoding membrane and secreted proteins important
            for mouse development
  JOURNAL   Proc Natl Acad Sci U S A 92 (14), 6592-6596 (1995)
   PUBMED   7604039
REFERENCE   7  (bases 1 to 7648)
  AUTHORS   Schaapveld,R.Q., van den Maagdenberg,A.M., Schepens,J.T.,
            Weghuis,D.O., Geurts van Kessel,A., Wieringa,B. and Hendriks,W.J.
  TITLE     The mouse gene Ptprf encoding the leukocyte common antigen-related
            molecule LAR: cloning, characterization, and chromosomal
            localization
  JOURNAL   Genomics 27 (1), 124-130 (1995)
   PUBMED   7665159
REFERENCE   8  (bases 1 to 7648)
  AUTHORS   Schepens,J., Zeeuwen,P., Wieringa,B. and Hendriks,W.
  TITLE     Identification and typing of members of the protein-tyrosine
            phosphatase gene family expressed in mouse brain
  JOURNAL   Mol Biol Rep 16 (4), 241-248 (1992)
   PUBMED   1454056
REFERENCE   9  (bases 1 to 7648)
  AUTHORS   Gebbink,M.F., van Etten,I., Hateboer,G., Suijkerbuijk,R.,
            Beijersbergen,R.L., Geurts van Kessel,A. and Moolenaar,W.H.
  TITLE     Cloning, expression and chromosomal localization of a new putative
            receptor-like protein tyrosine phosphatase
  JOURNAL   FEBS Lett 290 (1-2), 123-130 (1991)
   PUBMED   1655529
REFERENCE   10 (bases 1 to 7648)
  AUTHORS   Streuli,M., Krueger,N.X., Hall,L.R., Schlossman,S.F. and Saito,H.
  TITLE     A new member of the immunoglobulin superfamily that has a
            cytoplasmic region homologous to the leukocyte common antigen
  JOURNAL   J Exp Med 168 (5), 1523-1530 (1988)
   PUBMED   2972792
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL807774.10, BU056582.1, AI385919.1, CD352108.1, BU055092.1,
            AL626764.6, CV556730.1, CK634962.1, CA315396.1, CX201972.1 and
            AK133085.1.
            
            On Oct 7, 2006 this sequence version replaced NM_011213.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.360598.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-218               AL807774.10        43841-44058         c
            219-772             BU056582.1         101-654
            773-1077            AI385919.1         154-458
            1078-1678           CD352108.1         4-604
            1679-2097           BU055092.1         346-764
            2098-2156           AL626764.6         205202-205260       c
            2157-2462           AL626764.6         201729-202034       c
            2463-2614           AL626764.6         200980-201131       c
            2615-3295           CV556730.1         20-700
            3296-3916           CK634962.1         77-697
            3917-4462           CA315396.1         133-678
            4463-4884           CX201972.1         282-703
            4885-6866           AK133085.1         132-2113
            6867-7648           AL626764.6         178456-179237       c
FEATURES             Location/Qualifiers
     source          1..7648
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 54.47 cM"
     gene            1..7648
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /note="protein tyrosine phosphatase receptor type F"
                     /db_xref="GeneID:19268"
                     /db_xref="MGI:MGI:102695"
     exon            1..218
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            219..298
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            299..434
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     CDS             344..6040
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /EC_number="3.1.3.48"
                     /note="leukocyte antigen-related (LAR) PTP receptor;
                     Receptor-type tyrosine-protein phosphatase F; leukocyte
                     common antigen related"
                     /codon_start=1
                     /product="receptor-type tyrosine-protein phosphatase F
                     precursor"
                     /protein_id="NP_035343.2"
                     /db_xref="CCDS:CCDS18546.1"
                     /db_xref="GeneID:19268"
                     /db_xref="MGI:MGI:102695"
                     /translation="MAPEPAPGRRMVPLVPALVMLGLMAGAHGDSKPVFVKVPEDQTG
                     LSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDE
                     AIYECTATNSLGEINTSAKLSVLEEDQLPSGFPTIDMGPQLKVVEKGRTATMLCAAGG
                     NPDPEISWFKDFLPVDPAASNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYS
                     APANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED
                     EMPVGRNVLELSNVMRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATS
                     VTLTWDSGNTEPVSFYGIQYRAAGTDGPFQEVDGVASTRYSIGGLSPFSEYAFRVLAV
                     NSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVY
                     YTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQ
                     QGVPAQPADFQANAESDTRIQLSWLLPPQERIVKYELVYWAAEDEGQQHKVTFDPTSS
                     YTLEDLKPDTLYHFQLAARSDLGVGVFTPTVEARTAQSTPSAPPQKVTCVSTGSTTVR
                     VSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRV
                     WVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQ
                     IRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGA
                     RSKPKVVTTTGAVPGRPTMMVSTTAMHTALLQWHPPKELPGELLGYRLQYRRADEARP
                     NTIDFGKDDQHFTVTGLHKGATYVFRLAAKNRAGPGEEFEKEITTPEDVPSGFPQNLR
                     VTGLTTSTTELTWDPPVLAERNGHITNYTVVYRDINSQLELQNVTNDTHLTLLGLKPD
                     TTYDIKVRAHTSKGAGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYK
                     SAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAP
                     DLLPQKPLPASAFIEDGRFSLSMPQVQDPSLVRWFYIVVVPIDRVGGNLLAPRWNTPE
                     ELELDELLEAIEQGEEKQRRRRRQAERLKPYVAAQVDVLPDTFTLGDKKSYRGFYNRP
                     LSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVLAV
                     ILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDH
                     PPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAY
                     DHSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTAT
                     VVMMTRLEEKSRVKCDQYWPVRGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEK
                     RELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVI
                     DAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARN
                     LYAHIQKLGQVPPGESVTAMELEFKLLANSKAHTSRFVSANLPCNKFKNRLVNIMPYE
                     LTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTII
                     VMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSR
                     TIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFIT
                     LSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT"
     exon            435..580
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            581..722
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            723..911
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1022
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1292
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1874
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..2011
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2156
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            2157..2462
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            2463..2656
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            2657..2774
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            2775..3353
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            3354..3451
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            3452..3705
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            3706..3799
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            3800..4018
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            4019..4173
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            4174..4289
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            4290..4387
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            4388..4511
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            4512..4687
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            4688..4807
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            4808..4962
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            4963..5248
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            5249..5427
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            5428..5554
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            5555..5680
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            5681..5835
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            5836..5971
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     exon            5972..7648
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7614..7619
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /note="hexamer: AATAAA"
     polyA_site      7648
                     /gene="Ptprf"
                     /gene_synonym="LAR; LARS; RPTP-LAR"
                     /note="major polyA site"
ORIGIN      
        1 gggcgcgcgc ggctggagct ggcgcgggag cggtggcggc ggcggcggca gaggcggcgg
       61 ctccggctcc agctccggct ccggctccgg ctcctgctcg ggcggcggtg gaggtggcgg
      121 tggcgggagc gggcgacggc ggcggcagcg gcggactgag aacggcggcc tcagcggctc
      181 gaggggggac atgcagaccg acggcccccg gagaggcgga aggagcggag gccctggtgc
      241 cctgccctca gtgctgactg cccagcgaga gtgactggta taagcaagca gagacccggt
      301 ggattgtctt aggctgtggc tggctgtgga gctagaaccc tggatggctc ccgagccagc
      361 cccagggagg aggatggtgc cccttgtgcc tgctctcgtg atgcttggtt tgatggcagg
      421 tgctcatggc gacagcaaac ccgtctttgt taaggtcccc gaggaccaga ctgggctgtc
      481 gggaggggtg gcctccttcg tgtgccaagc cacaggggaa cccaagcctc gaattacgtg
      541 gatgaagaag gggaagaaag tcagctccca gcgctttgag gtaattgagt ttgacgatgg
      601 agcagggtca gtgctgcgga tccagccatt acgagtgcag cgagacgaag ccatctatga
      661 gtgcacagcc acgaacagtc tcggggagat caacacaagt gccaagctgt cagtgcttga
      721 agaggaccag ctgccgtctg ggttcccgac tatcgacatg ggacctcagc tgaaggtggt
      781 ggagaagggt cgcactgcca ccatgctgtg tgcagccggt gggaacccag accctgagat
      841 ctcttggttc aaagacttcc ttcctgtgga ccctgctgca agcaacggtc gtatcaaaca
      901 gctgcgatca ggtgcattgc agatagagag cagcgaggag tctgaccaag gcaagtacga
      961 gtgtgtggcc accaactctg caggcacacg ctactcggcc cccgccaacc tgtatgtgcg
     1021 agtgcgtcgc gtggctcctc gtttctccat ccctcccagc agccaagagg tgatgccggg
     1081 cggcagcgtg aatctcacat gtgtggcagt gggcgcgccc atgccgtatg tgaaatggat
     1141 gatgggcgcc gaggaactga ccaaagagga tgagatgcca gtcggccgaa atgttctgga
     1201 gctcagcaat gtcatgcgat ctgccaacta tacctgtgtg gccatctctt cattaggcat
     1261 gatagaagcc acggcccagg tcacagtaaa agctctgcca aagcctccaa ttgatcttgt
     1321 ggtgacagag acaaccgcca ccagtgttac tctgacatgg gactctggaa ataccgagcc
     1381 tgtgtccttc tacggcatcc agtaccgcgc agctggcaca gacggcccct tccaggaagt
     1441 ggatggtgtg gccagcaccc gatacagcat tggtggcctc agcccctttt cggaatatgc
     1501 tttccgtgtg ttggctgtta acagcattgg gcgaggacca cccagtgagg cagtgcgagc
     1561 acgcacgggg gagcaggcac cctccagccc tccgcgccgt gtgcaggctc gaatgcttag
     1621 cgccagcacc atgctggtcc agtgggaacc acctgaagag cccaatggcc tggtacgggg
     1681 atatcgcgtc tactataccc cagattcccg acgccctttg agcgcctggc acaagcataa
     1741 cactgacgca ggactcctta ccaccgtggg cagcctgcta cctggcatca cctacagcct
     1801 ccgagtcctt gccttcactg ctgtgggtga cggcccaccc agccccacca tccaagtcaa
     1861 gacacagcag ggagtgcctg cacagcctgc ggacttccag gctaacgctg agtcggacac
     1921 caggatccag ctctcgtggc tgctgccccc gcaggagcgg atcgtcaagt atgagctggt
     1981 gtactgggca gccgaggatg agggccagca gcacaaggtg accttcgacc ccacctcctc
     2041 ctacactctg gaggacctga agcctgacac attgtaccac ttccagctgg ctgcccgttc
     2101 agatttgggg gtgggcgtct tcacgcccac cgtagaggcc cgtacagcac agtccacccc
     2161 atcagcccct ccccagaagg tgacatgtgt gagcacgggc tccaccacgg tccgggtaag
     2221 ttgggttcca ccgccggccg acagccgcaa cggcattatc acccagtact ccgtggccta
     2281 tgaggcagtg gacggcgaag accgtaagcg acatgtggtg gatggcatca gccgtgagca
     2341 ttccagctgg gacctgctgg gcctggagaa gtggacggag taccgggtgt gggtgcgggc
     2401 acacacagat gtgggccctg gccctgagag cagcccggtg ctggtgcgca ccgatgagga
     2461 cgtgcctagc gggccaccac ggaaggtaga ggttgagcct ctgaactcca ctgctgtgca
     2521 tgtctcctgg aagctgcccg tccccaacaa gcagcacgga cagattcgtg gctaccaggt
     2581 cacctatgtg cggttggaga atggtgagcc ccgaggccaa cccatcatcc aggatgtcat
     2641 gctggctgag gctcaggaga ccaccatcag cggcctcacc cccgagacca cctactccat
     2701 caccgtcgct gcctacacca ctaaggggga tggtgcccga agcaagccca aggtggttac
     2761 tacaacaggg gcagtcccag gacggcccac catgatggtc agcaccacgg ccatgcacac
     2821 cgcgctgctg cagtggcacc cacccaagga gctgcctgga gagctgctgg gctaccgtct
     2881 ccaataccgg cgggccgacg aggcgcggcc caacaccata gactttggca aggatgacca
     2941 acattttaca gtcaccggcc tgcacaaagg ggccacctac gtcttccggc tcgctgccaa
     3001 gaaccgggct ggcccaggag aagagtttga gaaagagatc accacccccg aggatgtgcc
     3061 cagtggcttt cctcaaaatc ttcgagtgac aggactgacc acatctacca cggaactgac
     3121 ctgggacccg ccggtgctgg cggagaggaa tggtcacatc accaactata ctgtggtcta
     3181 ccgtgacatc aacagccagc ttgaactaca gaatgtcacc aacgacacac accttacact
     3241 cttgggcctt aaaccggaca ccacttatga catcaaggtc cgtgcacata ccagcaaagg
     3301 cgccggccct ctcagcccca gcatccagtc ccggaccatg cccgtggagc aagtgtttgc
     3361 caagaatttc cgtgtggccg ctgcgatgaa gacatctgtg ctgctcagtt gggaggtccc
     3421 cgactcttat aagtcagctg tgcccttcaa gatcctgtac aatgggcaga gcgtggaggt
     3481 ggatgggcac tcgatgcgga agctgattgc agacctgcaa cccaacacgg agtactcctt
     3541 cgtcctgatg aatcgtggca gtagcgccgg gggcctacag cacctggtgt ccatccgcac
     3601 tgccccggac ctcctacccc agaagccact gcctgcctcc gcctttatag aggatggccg
     3661 cttctccctc tccatgcctc aagtgcagga cccctcgcta gtcaggtggt tctacattgt
     3721 ggtggtgccc attgaccgtg tgggcgggaa cttgctggca ccaagatgga acacaccaga
     3781 ggagttggag ctggacgagc ttctggaggc catcgagcag ggcgaggaga aacagcggag
     3841 gcgccggcgc caagcagagc ggctgaagcc ttatgtggcg gcccaagtgg atgtgctccc
     3901 tgacaccttc accctggggg acaagaagag ctaccgcggc ttctacaacc ggcccctgtc
     3961 tccggatctg agttaccagt gcttcgttct cgcctccctc aaggaaccca tggaccagaa
     4021 gcgctacgcc tccagcccct actcggacga gattgtagtc caggtgacgc cagcacagca
     4081 gcaggaggag cccgagatgc tgtgggtgac aggccctgtc ctggcggtca ttctcatcat
     4141 actcattgtc atcgccatcc tcctgttcaa gaggaagaga acacactccc catcatcaaa
     4201 ggatgagcag tcaatcgggc tgaaggactc cctgttggcc cactcttctg accctgtgga
     4261 gatgcgaagg cttaactacc agaccccagg tatgcgagac cacccgccca tccccatcac
     4321 tgacctggca gacaatattg agcgcctcaa agccaacgat gggctcaagt tctcccagga
     4381 gtatgagtcc attgaccctg gacagcagtt cacatgggag aattccaact cggaggtgaa
     4441 caagcccaag aaccgctatg caaatgtcat tgcctatgac cattctcgag tcctcctcac
     4501 ctccattgat ggtgttcctg ggagtgacta catcaatgcc aactacattg atggctaccg
     4561 aaagcagaat gcctacatcg ccacacaggg tccgctgccc gagaccatgg gcgatttctg
     4621 gaggatggtg tgggaacagc gcacagccac agtggtcatg atgaccaggc tagaggagaa
     4681 atcccgggtg aagtgtgatc agtattggcc agtccgtggc actgagacct atggcctcat
     4741 tcaggtgacc ctggtggaca ctgtggagtt ggccacatac accatgcgca cctttgccct
     4801 ccataagagt ggctccagtg agaagcgtga gctgcgtcag ttccagttca tggcctggcc
     4861 agaccacggc gttcctgagt accccactcc catcttggcc ttcctgagac gggtcaaggc
     4921 ctgtaaccca ctagatgcgg ggcccatggt ggtgcattgc agtgcgggtg tggggcgcac
     4981 aggctgcttc atcgtcatcg acgcaatgct ggagcgtatg aagcacgaga agacggttga
     5041 catctatggc cacgtgacgt gcatgcgctc acaaaggaac tacatggtgc agaccgagga
     5101 ccagtatgtg ttcatccacg aggccctgct agaggctgcc atgtgcggac acaccgaggt
     5161 gctcgctcgg aacctctatg cccacatcca gaagctaggc caagtgcctc ccggggagag
     5221 cgtcacggcc atggaacttg agttcaagtt gctggccaac tccaaggccc acacgtcgcg
     5281 ctttgtcagt gccaacctgc cctgcaacaa gttcaagaac cgcctagtga acatcatgcc
     5341 ctatgagctg acccgagtgt gcttgcaacc catccgtggt gtggagggct cagactacat
     5401 caatgccagc tttctagatg gctacagaca gcagaaggcc tacatagcta cacaggggcc
     5461 tctggcagag agcaccgagg acttctggcg catgttatgg gagcacaatt ccaccatcat
     5521 cgtcatgctg accaagcttc gggagatggg cagggagaaa tgtcaccagt actggccagc
     5581 agagcgctcc gctcgctatc agtacttcgt tgttgacccg atggctgagt acaacatgcc
     5641 ccagtatatt ctgcgtgaat tcaaagtcac agacgcccgg gatgggcagt caaggacaat
     5701 ccgacagttc cagtttacag actggccaga gcaaggagta cccaaaacag gtgaaggctt
     5761 catcgacttc atcgggcagg tgcacaagac aaaggagcag tttggccagg atgggcccat
     5821 cacggtgcac tgcagtgctg gtgtgggccg caccggtgtg ttcatcaccc tgagcattgt
     5881 cctggagcgc atgcggtatg agggtgtggt tgacatgttc cagaccgtga agaccctccg
     5941 cacacagcgc cctgcaatgg tgcagacaga ggaccaatac cagctgtgct accgtgcggc
     6001 cctggaatac ctcggcagct ttgatcacta tgcaacgtaa ctactgctcc cctctcctcc
     6061 gacgctcccc cgcggggctc cggaggggac ccagctcctc tgagccatac caaccatcgt
     6121 ccagccctcc tgcacggatg ctgttgccgg cagagcacag cccactggga tcacagcatt
     6181 tcggggaaca ttgccacacc agtcagagag cccagaacac ctgggcaagt aggcggactg
     6241 gcagcctggc tctgggccct cgtccaccgg gccaagtgga gccccgcttc aagctctctg
     6301 ttcagctccg cgttctcatg cttctcatgg ggtgggaaaa gggggcaaag cccccacttt
     6361 ttatacacta ggcggggtag actgcggggt cctagcctct tcctccgact ttgcttttgc
     6421 aggtctttca ctgcagatgg ggctgctgtg ggagttggga cttgtttgtt ttcctttttg
     6481 agttcacgtt ggatcctttc ttgtacaact tctgcggaag gacacagtag taactcgcct
     6541 tccttgtgca gagctagggc cctacctgag caagtcggct gtggcccggg aggcagcgtg
     6601 actcctgctg tcctccagcc tttcagatga gatcctattc cagccaaatg cagggaaaca
     6661 ctttattttg tttgttttag gttttgtttt tccttgagag ccttttttta ggccccacag
     6721 acagtggtgg gtggggaggc gataggaaac acattcccca gtgtgcattt aacattcata
     6781 gcctacaacc acagacgtgt ctgggggagc ctggcaaggc gttcctcgtc accatcgtgt
     6841 ttgcaaaggt tcaaaaaaca aaaatcaaaa aaaaaaaaaa acataaaaat attttttttt
     6901 aagaaaagaa ataaagattc atcccctggc ctctacttca gattcgaagt gggaggcaac
     6961 tcaatgtgcc tggggctcgc catgggccca cagagtctcg ctatcatccc cagcgtcgca
     7021 gtgtggcagg tgtttgtagg ctgtgggttc tggccacctc gggaaatgaa tggcacaggt
     7081 gagggcctgt gccacgcccc acacacctca gggccaagcg ggggcgtggc tggcccttca
     7141 ggtcaggcca gtgggcctgg tagcacatgt ctgtcctcag ccggacagat gctttctctc
     7201 ctggtttgca gctgtcttca aatcccccca tgacccgctc ttcccactcc ttcaagttgc
     7261 cctcacaaac caatgtggca agactactgg acttgtatcc atggtactat actcagtcct
     7321 cttatctcag cttgctgagg ggcagggaga gggtctcttc ctctgggcag cactatctag
     7381 ataggtaagt gggggcgggg aagggtgcat agctgtttta gccgagggac tcgataccga
     7441 cgtccccaga tatagctagg ctaagtcaag atcaacagtc cggggttggt ggtgttggat
     7501 gaaacattca tttttacctt gtggatgcta gtgctgtaga gttcactgtt gtacacagtc
     7561 tgttttctat ttgttaagaa aaactacagc atcattgcat acttcttgat ggtaataaat
     7621 ttgaataatc aagatttctt acacacta
//
