LOCUS       NM_011212               5411 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus protein tyrosine phosphatase receptor type E (Ptpre),
            transcript variant 2, mRNA.
ACCESSION   NM_011212
VERSION     NM_011212.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5411)
  AUTHORS   Han,X., Huang,S., Xue,P., Fu,J., Liu,L., Zhang,C., Yang,L., Xia,L.,
            Sun,L., Huang,S.K. and Zhou,Y.
  TITLE     LncRNA PTPRE-AS1 modulates M2 macrophage activation and
            inflammatory diseases by epigenetic promotion of PTPRE
  JOURNAL   Sci Adv 5 (12), eaax9230 (2019)
   PUBMED   31844669
  REMARK    GeneRIF: We describe a new regulatory mechanism, where an
            unreported lncRNA, PTPRE-AS1, targets receptor-type tyrosine
            protein phosphatase epsilon (PTPRE) to regulate macrophage
            activation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5411)
  AUTHORS   Cohen-Sharir,Y., Kuperman,Y., Apelblat,D., den Hertog,J.,
            Spiegel,I., Knobler,H. and Elson,A.
  TITLE     Protein tyrosine phosphatase alpha inhibits hypothalamic leptin
            receptor signaling and regulates body weight in vivo
  JOURNAL   FASEB J 33 (4), 5101-5111 (2019)
   PUBMED   30615487
REFERENCE   3  (bases 1 to 5411)
  AUTHORS   Branco,M.R., King,M., Perez-Garcia,V., Bogutz,A.B., Caley,M.,
            Fineberg,E., Lefebvre,L., Cook,S.J., Dean,W., Hemberger,M. and
            Reik,W.
  TITLE     Maternal DNA Methylation Regulates Early Trophoblast Development
  JOURNAL   Dev Cell 36 (2), 152-163 (2016)
   PUBMED   26812015
REFERENCE   4  (bases 1 to 5411)
  AUTHORS   Levy-Apter,E., Finkelshtein,E., Vemulapalli,V., Li,S.S.,
            Bedford,M.T. and Elson,A.
  TITLE     Adaptor protein GRB2 promotes Src tyrosine kinase activation and
            podosomal organization by protein-tyrosine phosphatase in
            osteoclasts
  JOURNAL   J Biol Chem 289 (52), 36048-36058 (2014)
   PUBMED   25381250
  REMARK    GeneRIF: GRB2 physically links cyt-PTPe with Src and enables
            cyt-PTPe to activate Src downstream of activated integrins in
            osteoclast-like cells.
REFERENCE   5  (bases 1 to 5411)
  AUTHORS   Finkelshtein,E., Lotinun,S., Levy-Apter,E., Arman,E., den
            Hertog,J., Baron,R. and Elson,A.
  TITLE     Protein tyrosine phosphatases epsilon and alpha perform
            nonredundant roles in osteoclasts
  JOURNAL   Mol Biol Cell 25 (11), 1808-1818 (2014)
   PUBMED   24694598
  REMARK    GeneRIF: PTPs alpha and epsilon play distinct roles in osteoclasts.
REFERENCE   6  (bases 1 to 5411)
  AUTHORS   Elson,A. and Leder,P.
  TITLE     Protein-tyrosine phosphatase epsilon. An isoform specifically
            expressed in mouse mammary tumors initiated by v-Ha-ras OR neu
  JOURNAL   J Biol Chem 270 (44), 26116-26122 (1995)
   PUBMED   7592814
REFERENCE   7  (bases 1 to 5411)
  AUTHORS   Hendriks,W., Schepens,J., Brugman,C., Zeeuwen,P. and Wieringa,B.
  TITLE     A novel receptor-type protein tyrosine phosphatase with a single
            catalytic domain is specifically expressed in mouse brain
  JOURNAL   Biochem J 305 (Pt 2) (Pt 2), 499-504 (1995)
   PUBMED   7832766
REFERENCE   8  (bases 1 to 5411)
  AUTHORS   Kaneko,Y., Takano,S., Okumura,K., Takenawa,J., Higashituji,H.,
            Fukumoto,M., Nakayama,H. and Fujita,J.
  TITLE     Identification of protein tyrosine phosphatases expressed in murine
            male germ cells
  JOURNAL   Biochem Biophys Res Commun 197 (2), 625-631 (1993)
   PUBMED   8267598
REFERENCE   9  (bases 1 to 5411)
  AUTHORS   Schepens,J., Zeeuwen,P., Wieringa,B. and Hendriks,W.
  TITLE     Identification and typing of members of the protein-tyrosine
            phosphatase gene family expressed in mouse brain
  JOURNAL   Mol Biol Rep 16 (4), 241-248 (1992)
   PUBMED   1454056
REFERENCE   10 (bases 1 to 5411)
  AUTHORS   Yi,T., Cleveland,J.L. and Ihle,J.N.
  TITLE     Identification of novel protein tyrosine phosphatases of
            hematopoietic cells by polymerase chain reaction amplification
  JOURNAL   Blood 78 (9), 2222-2228 (1991)
   PUBMED   1932742
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151838.6, AC151841.5 and AC123047.3.
            
            On Jul 26, 2007 this sequence version replaced NM_011212.2.
            
            Transcript Variant: This variant (2) contains an alternate exon in
            the 5' end compared to variant 1. The resulting isoform (b) is
            shorter at the N-terminus compared to isoform a. Variants 2 and 3
            both encode the same isoform (b).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U35368.1, D83484.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-293               AC151838.6         35929-36221         c
            294-316             AC151841.5         45960-45982         c
            317-435             AC151841.5         3471-3589           c
            436-529             AC123047.3         86129-86222
            530-603             AC123047.3         86466-86539
            604-740             AC123047.3         88269-88405
            741-831             AC123047.3         93429-93519
            832-908             AC123047.3         97620-97696
            909-945             AC123047.3         98315-98351
            946-1043            AC123047.3         99363-99460
            1044-1163           AC123047.3         101927-102046
            1164-1327           AC123047.3         103373-103536
            1328-1463           AC123047.3         104098-104233
            1464-1613           AC123047.3         105075-105224
            1614-1707           AC123047.3         105484-105577
            1708-1784           AC123047.3         107121-107197
            1785-1919           AC123047.3         108624-108758
            1920-2045           AC123047.3         112581-112706
            2046-2212           AC123047.3         113469-113635
            2213-2348           AC123047.3         115928-116063
            2349-5411           AC123047.3         117608-120670
FEATURES             Location/Qualifiers
     source          1..5411
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 81.27 cM"
     gene            1..5411
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /note="protein tyrosine phosphatase receptor type E"
                     /db_xref="GeneID:19267"
                     /db_xref="MGI:MGI:97813"
     exon            1..293
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            294..316
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            317..435
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     CDS             324..2423
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /EC_number="3.1.3.48"
                     /note="isoform b precursor is encoded by transcript
                     variant 2; receptor-type tyrosine-protein phosphatase
                     epsilon; R-PTP-epsilon; protein-tyrosine phosphatase
                     epsilon"
                     /codon_start=1
                     /product="receptor-type tyrosine-protein phosphatase
                     epsilon isoform b precursor"
                     /protein_id="NP_035342.3"
                     /db_xref="CCDS:CCDS21944.1"
                     /db_xref="GeneID:19267"
                     /db_xref="MGI:MGI:97813"
                     /translation="MEPFCPLLLASFSLSLARAGQGNDTTPTESNWTSTTAGPPDPGA
                     SQPLLTWLLLPLLLLLFLLAAYFFRFRKQRKAVVSSNDKKMPNGILEEQEQQRVMLLS
                     RSPSGPKKFFPIPVEHLEEEIRVRSADDCKRFREEFNSLPSGHIQGTFELANKEENRE
                     KNRYPNILPNDHCRVILSQVDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFW
                     RMVWEQRSATIVMLTNLKERKEEKCYQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKF
                     CIHPQLPDSCKAPRLVSQLHFTSWPDFGVPFTPIGMLKFLKKVKTLNPSHAGPIVVHC
                     SAGVGRTGTFIVIDAMMDMIHSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLE
                     YYLYGDTELDVSSLERHLQTLHSTATHFDKIGLEEEFRKLTNVRIMKENMRTGNLPAN
                     MKKARVIQIIPYDFNRVILSMKRGQEFTDYINASFIDGYRQKDYFMATQGPLAHTVED
                     FWRMVWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGDITIEIKSDTLSEAISVR
                     DFLVTFKQPLARQEEQVRMVRQFHFHGWPEVGIPAEGKGMIDLIAAVQKQQQQTGNHP
                     ITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCY
                     KVVQDFIDIFSDYANFK"
     exon            436..529
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            530..603
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            604..740
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            741..831
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            832..908
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            909..945
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1043
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1163
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1327
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1463
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            1464..1613
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            1614..1707
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            1708..1784
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..1919
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            1920..2045
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            2046..2212
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2348
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     exon            2349..5411
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5386..5391
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /note="hexamer: AATAAA"
     polyA_site      5411
                     /gene="Ptpre"
                     /gene_synonym="PTPe; PTPepsilon; RPTPepsilon"
                     /note="major polyA site"
ORIGIN      
        1 agagctggag gcggccggac cgggccagac agatttcctg ctctcctgta gggctgaggg
       61 ctgccggctg cgggctacgg gctgcgggct acaggctacg ggctacggac tgcgggctgc
      121 gagagaagtc accggcggcg caggtacctc actgcctacg cgcgtcccca cgaccctccc
      181 tcgcgccggc ggggacagcg gacgccccgg agcggagcgc gtcgggcggg cgcccgggag
      241 atgcggagtc gccgcggcgg agcgatcggg gctacagcac cggtccctgg gagactatag
      301 ccctcatttc cccttggtgc accatggagc ccttctgtcc actcctgctg gcaagtttta
      361 gcttgtcgct cgccagagct ggccagggca acgacaccac cccaacagag agcaactgga
      421 ccagcacaac tgcaggccct ccggaccctg gtgcatccca gccgctgctc acctggctgc
      481 tgctgcccct gctcctcctc ctgttcctgc ttgcagccta cttcttcagg ttccggaagc
      541 agaggaaggc cgtggtcagc agcaacgaca agaaaatgcc taacgggatc ttagaagagc
      601 aagagcagca gagagtgatg ctgctgagca gatctccatc aggccccaag aagttcttcc
      661 ccatccccgt ggagcacctg gaggaggaga tccgggtgag atctgcggat gactgcaagc
      721 gattccgaga ggagttcaat tcattgccat ctggacacat acaaggaacc tttgaactag
      781 caaataaaga agaaaacaga gaaaaaaaca gataccccaa cattctgccc aatgatcatt
      841 gcagagtgat tttgagccaa gtggatggaa tcccctgctc tgactacatt aatgcttcct
      901 acatcgatgg ctacaaagaa aagaacaaat tcatagcagc tcaaggccct aagcaggaga
      961 cagtgaatga cttctggaga atggtctggg agcaaaggtc agccaccatc gtcatgttga
     1021 cgaacctgaa ggagaggaag gaggagaagt gctaccagta ctggccagac cagggctgtt
     1081 ggacctacgg caacatccgg gtgtgtgtag aggactgcgt ggtcctggtg gattacacga
     1141 tccgaaagtt ctgcatccat ccgcaactcc cagacagctg caaagccccg cggctggtct
     1201 cacagctgca cttcaccagc tggcctgact tcggggtgcc gtttaccccc atcgggatgc
     1261 tcaagttcct gaagaaagtg aagacactca acccctcaca tgctgggccc attgtggttc
     1321 actgtagcgc gggcgtgggt cggactggca ccttcattgt gatcgatgcc atgatggaca
     1381 tgatacactc ggagcagaag gttgacgtct ttgagtttgt gtctagaatc cgcaatcagc
     1441 gccctcagat ggtccagacg gatgttcagt atacattcat ctaccaagcc ttactggaat
     1501 actacctcta tggggacaca gagctggatg tgtcctccct ggagaggcac ctgcagacgc
     1561 tccatagcac agccacccat tttgacaaga tcgggctgga ggaagagttc aggaagctga
     1621 ccaacgtgcg aatcatgaag gagaacatga ggacgggcaa cctgcctgcc aacatgaaga
     1681 aggcccgcgt catccagatc attccatatg acttcaatcg ggtcatcctg tccatgaaaa
     1741 gagggcaaga gttcacagac tatatcaacg catccttcat agatggctac aggcagaagg
     1801 actacttcat ggccacacag gggcctctgg ctcacacagt tgaggacttc tggaggatgg
     1861 tatgggagtg gaagtctcac acaatcgtca tgctgacgga ggtgcaggag cgggaacagg
     1921 ataaatgcta ccagtattgg ccaacggagg gctcggtgac tcatggagat ataactatag
     1981 agataaagag cgacaccctg tctgaagcaa tcagcgtacg agactttctg gttaccttca
     2041 aacagcccct ggcccgccag gaagagcagg tccgcatggt gagacaattc catttccatg
     2101 gctggcctga ggttggcatc cccgctgaag gcaaaggcat gattgacctg attgcagcag
     2161 tgcagaagca gcagcagcag acgggcaacc accccatcac cgtgcactgc agcgcgggag
     2221 cagggcggac aggtacattc atagcactca gtaacatttt ggaacgagtg aaagccgagg
     2281 gactcctaga cgtgtttcaa gctgtgaaga gcttaagact tcagagacca cacatggtgc
     2341 agaccctgga gcaatatgaa ttctgctaca aagtggtaca agattttatc gatatatttt
     2401 ctgattatgc taatttcaaa tgaagattcc tgccttaaaa tattttttaa tttaatggtc
     2461 agtatatttt gtaaaaaaaa aaaaagagat catgttaatt tatttcctag tggatattaa
     2521 tatccttcct aattcctttg tatatatttt gttatgttct aaaggctacc tgctgtaagg
     2581 ttattaaatt gtaaatgccc tttttaaaaa ttggaataac atgttaaggt caaatactat
     2641 ctggaaagat atatatttct gctaacacca gtcagtatct tagttctatt agattcatgt
     2701 tatgtggtgt cccacatcag gtgtcacatg gtgtcacaca tcatgcatct gtaaatgtag
     2761 ttcttaacat gtcaaatgtg tttgtgagaa gacactaacc cctgaaaccc cctgtggaga
     2821 aaccagtaga ggactccgag tcagagcaca tttactctcc ccaccaactg tcgcacccag
     2881 ggcatcggaa tgtggcaaac agtgtgcatg ggggctttgg tagagtcctg ggtctcagcc
     2941 atgtggtcca tccttgcatt tgaaagatca gagtggaagc agacacggca gtgcatcact
     3001 gcactgctag cacgtgggag gctggggcat aaggatttgg tccaggtcag gccaggccag
     3061 cttgggctac agtgagactc tgtaacacaa caaacaacaa acacccagag ggttttgaaa
     3121 cccaaatcca ggtctcagat gtacaaggtg tagatggtgg tgactttcct atgagtttta
     3181 aaaggcattc atgagaggct gtgtagtgcc actgtaggct tgataaagag atgtgttata
     3241 ccaggccatc tattctcaca ggcctccagt accctccaaa ctagccatct gagctgtgtt
     3301 cctggaacca cttgctgcct gcctgtgtgc ctggctcaga atccactcaa gctcattccc
     3361 aacggcccgc ccactgacac agctgcctgt actgacccta attgggccta caggctcaac
     3421 cacagctgca cacacacaca cacacacaca cacacacggt agaatggcca caaactgttg
     3481 cactgtcaat ttgctgatac tcaaccacag ctgcacacac acacacacac acacacacac
     3541 acacacacac acacacacac acacacacgg tagaatggcc acaaactgtt gcactgtcaa
     3601 tttgctgata gccatttcag gatgtcagat tttctttgta aaaagttaag atggtttgta
     3661 agaaaggaat tcttaaaaat ctagatttgt acagtttttt tcttaaatgt cccacctctt
     3721 ggtgtttaat ttttaaaaat gagagggggg gaagatccta atctaactta cctttggagg
     3781 aaaggctgct gagacctctg agttcaggtg gcagtgacag gcgcactgcc tgagagggta
     3841 ggttaggagg agggagagga ggaggaggaa tgtagaaaca ttgacttcaa taaaaattat
     3901 cttcctatgg catttagata cctagcaaat gagcacaatg taaaaaaaaa aaaaaaaaga
     3961 catctggtct aactcattga aggctttgaa cacagtttgg gaactttttt tttaaacttt
     4021 ttaaaagaga aatgaaaata caaaggcctt atctccatgg aggactgatc atgctcgcct
     4081 attgcacagt ttgttcttgt tcgtgtacaa gggacaaccc cagggtctgt cactgcttca
     4141 tacaggtgaa cgggtcacca cgcttatctc aagccccgca gctctgagtg tcccatccag
     4201 aggcacaagc tggcactcag catgcaggat gaaagcagac agtggccact gtcaccacca
     4261 ccaccagctg caggcagggc tggctgcctg tgctttgtgg gagctcccct tctctgagca
     4321 gccttggagc acaggcagaa gatggaagat ggaggagctt tccctggcca gtggtctcat
     4381 ttgtctccat cttagaccca agctcaacgc cttgctgtaa ctgaagcggg acagagggca
     4441 gtaagcccac tagaattaag gtgacctcac atgggtccca agccaaagtt cggccacgca
     4501 ccttggcacc ccaacttagt tactggtcct tagaatccca ggcatctctt gtatcaagaa
     4561 atgccttagg gtagatcttt tcaggatgtc tagaaaagta ttctaatgag tgtttttcct
     4621 caccttgggg ctgccccagg ttctcctgca ggcagagacc ctgcctgttt ctaaacagct
     4681 tgtctcattc cagagaaaaa cagaagccac gctcctgtgg gcacagttgg ggcagcactt
     4741 gtactttgga ggggccaatc cctctagtct cttgactaat gccatagcaa aattcagcct
     4801 ccgtaagaca cagagcctct gtgtacaagg ggtctcctag ggggaggagg gcggtctcag
     4861 catcttctct gtgtacctgg catgtccttt tcttcttcct tcaaagaagc tccggtgttt
     4921 atgacaccga caaccttctt agttctctgt tgcatgcggt tgtgctcaac gccaaacagt
     4981 catcagagct gagcgttctg atcaggtgcg tctcttggtc actgtgtgac ttgctttact
     5041 ctctctccat gggctggatg aacgaggaat gcacacctgt gttttccaag gtagttttat
     5101 gtgtttttaa aaccttttta aatgagcctg atacctgtgt ttcagcattt ggccacgttg
     5161 ttggtttttg tttttcatgt atatttactg atatattttt gtttgtaacc aagtcatgtt
     5221 taatttatgt gcaatcttta taatatgtgt atgtgttatg gttccaactc tcatatatta
     5281 ttccttgatc acatttatcg tttgatcttg ctctgattat gccagtgtat gtcgctgaat
     5341 tcttgagaca tgtgaactgc aagattgaaa acatccggat tcgagaataa atctctgact
     5401 accagcctgt a
//
