LOCUS       NM_001111316            5568 bp    mRNA    linear   ROD 02-MAY-2023
DEFINITION  Mus musculus protein tyrosine phosphatase, receptor type, C
            (Ptprc), transcript variant 1, mRNA.
ACCESSION   NM_001111316
VERSION     NM_001111316.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5568)
  AUTHORS   Chuang CK, Chen SF, Su YH, Chen WH, Lin WM, Wang IC and Shyue SK.
  TITLE     The Role of SCL Isoforms in Embryonic Hematopoiesis
  JOURNAL   Int J Mol Sci 24 (7), 6427 (2023)
   PUBMED   37047400
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5568)
  AUTHORS   Gu X, Heinrich A, Li SY and DeFalco T.
  TITLE     Testicular macrophages are recruited during a narrow fetal time
            window and promote organ-specific developmental functions
  JOURNAL   Nat Commun 14 (1), 1439 (2023)
   PUBMED   36922518
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5568)
  AUTHORS   Brioschi S, Belk JA, Peng V, Molgora M, Rodrigues PF, Nguyen KM,
            Wang S, Du S, Wang WL, Grajales-Reyes GE, Ponce JM, Yuede CM, Li Q,
            Baer JM, DeNardo DG, Gilfillan S, Cella M, Satpathy AT and Colonna
            M.
  TITLE     A Cre-deleter specific for embryo-derived brain macrophages reveals
            distinct features of microglia and border macrophages
  JOURNAL   Immunity (2023) In press
   PUBMED   36791722
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   4  (bases 1 to 5568)
  AUTHORS   Mlynarczyk C, Teater M, Pae J, Chin CR, Wang L, Arulraj T, Barisic
            D, Papin A, Hoehn KB, Kots E, Ersching J, Bandyopadhyay A, Barin E,
            Poh HX, Evans CM, Chadburn A, Chen Z, Shen H, Isles HM, Pelzer B,
            Tsialta I, Doane AS, Geng H, Rehman MH, Melnick J, Morgan W, Nguyen
            DTT, Elemento O, Kharas MG, Jaffrey SR, Scott DW, Khelashvili G,
            Meyer-Hermann M, Victora GD and Melnick A.
  TITLE     BTG1 mutation yields supercompetitive B cells primed for malignant
            transformation
  JOURNAL   Science 379 (6629), eabj7412 (2023)
   PUBMED   36656933
REFERENCE   5  (bases 1 to 5568)
  AUTHORS   Nyberg WA, Ark J, To A, Clouden S, Reeder G, Muldoon JJ, Chung JY,
            Xie WH, Allain V, Steinhart Z, Chang C, Talbot A, Kim S, Rosales A,
            Havlik LP, Pimentel H, Asokan A and Eyquem J.
  TITLE     An evolved AAV variant enables efficient genetic engineering of
            murine T cells
  JOURNAL   Cell 186 (2), 446-460 (2023)
   PUBMED   36638795
REFERENCE   6  (bases 1 to 5568)
  AUTHORS   Morse HC 3rd.
  TITLE     Genetic nomenclature for loci controlling surface antigens of mouse
            hemopoietic cells
  JOURNAL   J Immunol 149 (10), 3129-3134 (1992)
   PUBMED   1431091
  REMARK    Review article
            Erratum:[J Immunol 1993 Mar 15;150(6):2563]
REFERENCE   7  (bases 1 to 5568)
  AUTHORS   Capeless CG, Whitney G and Azen EA.
  TITLE     Chromosome mapping of Soa, a gene influencing gustatory sensitivity
            to sucrose octaacetate in mice
  JOURNAL   Behav Genet 22 (6), 655-663 (1992)
   PUBMED   1290451
REFERENCE   8  (bases 1 to 5568)
  AUTHORS   Kim JM, Brannan CI, Copeland NG, Jenkins NA, Khan TA and Moore KW.
  TITLE     Structure of the mouse IL-10 gene and chromosomal localization of
            the mouse and human genes
  JOURNAL   J Immunol 148 (11), 3618-3623 (1992)
   PUBMED   1350294
REFERENCE   9  (bases 1 to 5568)
  AUTHORS   Freund,J.G., Ahmed,A., Budd,R.E., Dorf,M.E., Sell,K.W.,
            Vannier,W.E. and Humphreys,R.E.
  TITLE     The L1210 leukemia cell bears a B lymphocyte specific, non-H-2
            linked alloantigen
  JOURNAL   J Immunol 117 (5 Pt.2), 1903-1905 (1976)
   PUBMED   62795
REFERENCE   10 (bases 1 to 5568)
  AUTHORS   Trowbridge,I.S. and Mazauskas,C.
  TITLE     Immunological properties of murine thymus-dependent lymphocyte
            surface glycoproteins
  JOURNAL   Eur J Immunol 6 (8), 557-562 (1976)
   PUBMED   61878
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK392851.1, AC159278.3, AK054056.1, CA575153.1, CA577897.1,
            AC122903.4 and BM239381.2.
            
            [WARNING] On May 6, 2023 this sequence was replaced by
            NM_001111316.3.
            
            On Jun 26, 2012 this sequence version replaced NM_001111316.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note:.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3765653.426590.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-468               CK392851.1         61-528
            469-553             AC159278.3         106335-106419       c
            554-3092            AK054056.1         236-2774
            3093-3340           CA575153.1         114-361
            3341-3849           CA577897.1         1-509
            3850-4857           AC122903.4         5913-6920
            4858-5568           BM239381.2         1-711               c
FEATURES             Location/Qualifiers
     source          1..5568
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 60.73 cM"
     gene            1..5568
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /note="protein tyrosine phosphatase, receptor type, C"
                     /db_xref="GeneID:19264"
                     /db_xref="MGI:MGI:97810"
     exon            1..112
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..3921
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /EC_number="3.1.3.48"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; leukocyte common antigen; receptor-type
                     tyrosine-protein phosphatase C; lymphocyte common antigen;
                     lymphocyte antigen 5"
                     /codon_start=1
                     /product="receptor-type tyrosine-protein phosphatase C
                     isoform 1 precursor"
                     /protein_id="NP_001104786.2"
                     /db_xref="CCDS:CCDS48383.2"
                     /db_xref="GeneID:19264"
                     /db_xref="MGI:MGI:97810"
                     /translation="MTMGLWLKLLAFGFALLDTEVFVTGQTPTPSDELSTTENALLLP
                     QSDPLPARTTESTPPSISERGNGSSETTYHPGVLSTLLPHLSPQPDSQTPSAGGADTQ
                     TFSSQADNPTLTPAPGGGTDPPGVPGERTVPGTIPADTAFPVDTPSLARNSSAASPTH
                     TSNVSTTDISSGASLTTLTPSTLGLASTDPPSTTIATTTKQTCAAMFGNITVNYTYES
                     SNQTFKADLKDVQNAKCGNEDCENVLNNLEECSQIKNISVSNDSCAPATTIDLYVPPG
                     TDKFSLHDCTPKEKANTSICLEWKTKNLDFRKCNSDNISYVLHCEPENNTKCIRRNTF
                     IPERCQLDNLRAQTNYTCVAEILYRGVKLVKNVINVQTDLGIPETPKPSCGDPAARKT
                     LVSWPEPVSKPESASKPHGYVLCYKNNSEKCKSLPNNVTSFEVESLKPYKYYEVSLLA
                     YVNGKIQRNGTAEKCNFHTKADRPDKVNGMKTSRPTDNSINVTCGPPYETNGPKTFYI
                     LVVRSGGSFVTKYNKTNCQFYVDNLYYSTDYEFLVSFHNGVYEGDSVIRNESTNFNAK
                     ALIIFLVFLIIVTSIALLVVLYKIYDLRKKRSSNLDEQQELVERDDEKQLMDVEPIHS
                     DILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKDARKPHNQNKNRYVDILPYDYNR
                     VELSEINGDAGSTYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMV
                     TRCEEGNRNKCAEYWPSMEEGTRAFKDIVVTINDHKRCPDYIIQKLNVAHKKEKATGR
                     EVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGID
                     AMLEGLEAEGKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSEL
                     HSCLHNMKKRDPPSDPSPLEAEYQRLPSYRSWRTQHIGNQEENKKKNRNSNVVPYDFN
                     RVPLKHELEMSKESEPESDESSDDDSDSEETSKYINASFVMSYWKPEMMIAAQGPLKE
                     TIGDFWQMIFQRKVKVIVMLTELVNGDQEVCAQYWGEGKQTYGDMEVEMKDTNRASAY
                     TLRTFELRHSKRKEPRTVYQYQCTTWKGEELPAEPKDLVSMIQDLKQKLPKASPEGMK
                     YHKHASILVHCRDGSQQTGLFCALFNLLESAETEDVVDVFQVVKSLRKARPGVVCSYE
                     QYQFLYDIIASIYPAQNGQVKKTNSQDKIEFHNEVDGGKQDANCVRPDGPLNKAQEDS
                     RGVGTPEPTNSAEEPEHAANGSASPAPTQSS"
     exon            113..136
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            137..265
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            266..412
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            413..553
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            554..625
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            626..649
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            650..865
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            866..1006
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1165
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1300
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            1301..1456
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            1457..1665
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1726
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            1727..1835
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            1836..1870
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            1871..1980
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2071
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            2072..2148
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            2149..2185
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            2186..2283
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            2284..2409
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            2410..2567
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            2568..2703
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            2704..2853
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            2854..2944
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            2945..3078
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            3079..3213
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            3214..3336
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            3337..3512
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            3513..3648
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
     exon            3649..5568
                     /gene="Ptprc"
                     /gene_synonym="B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4;
                     T200"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagacccta tttcttaggg gcacagctga tctccagata tgaccatggg tttgtggctc
       61 aaacttctgg cctttggatt tgcccttctg gacacagaag tctttgtcac agggcaaaca
      121 cctacaccca gtgatgaact gagcacaaca gagaatgccc ttcttctgcc tcaaagtgac
      181 cccttacctg ctcgcaccac tgaatccaca cccccaagca tctctgaaag aggaaatggc
      241 tcttcagaga ccacatatca tccaggtgtg ttatccacgc tgctgcctca cctgtcccca
      301 cagcctgact cgcagacgcc ctctgccgga ggagctgaca ctcagacatt cagcagccaa
      361 gctgacaatc ccacactcac gcctgctccc ggcggcggga ctgacccacc aggtgtgcca
      421 ggggagagga ctgtaccggg gaccattcct gcagacacag cctttcctgt tgataccccc
      481 agccttgcac gcaacagctc tgctgcctca cctacacaca cctccaatgt cagcaccaca
      541 gatatctctt caggtgccag cctcacaact cttacaccat ccactctggg ccttgcaagc
      601 actgaccctc caagcacaac catagctacc acaacgaagc aaacatgtgc tgccatgttt
      661 gggaacatta ctgtgaatta cacctatgaa tctagtaatc agacttttaa ggcagacctc
      721 aaagatgtcc aaaatgctaa gtgtggaaat gaggattgtg aaaacgtgtt aaataatcta
      781 gaagaatgct cacagataaa aaacatcagt gtgtctaatg actcatgtgc tccagctaca
      841 actatagatt tatatgtacc accagggact gacaagtttt cgctacatga ctgcacacca
      901 aaagaaaagg ctaatacttc aatttgtttg gagtggaaaa caaaaaacct tgatttcaga
      961 aaatgcaaca gtgacaatat ttcatatgta ctccactgtg agccagaaaa taatacaaaa
     1021 tgcattagaa gaaatacatt catacctgaa agatgtcagt tggacaacct tcgtgcccaa
     1081 acaaattaca catgtgtagc agaaatctta tatcgcggtg taaaactcgt caaaaatgtt
     1141 ataaatgtgc agacagattt ggggattcca gaaacgccta agcctagttg tggggatcca
     1201 gctgcaagaa aaacgttagt ctcttggcct gagcctgtat ctaaacctga gtctgcatct
     1261 aaaccccatg gatatgtttt atgctataag aacaattcag aaaaatgtaa aagtttgcct
     1321 aataatgtga ccagttttga ggtggaaagc ttgaaacctt ataaatacta tgaagtgtcc
     1381 ctacttgcct atgtcaatgg gaagattcaa agaaatggga ctgctgagaa gtgcaatttt
     1441 cacacaaaag cagatcgtcc ggacaaggtc aatggaatga aaacctcccg gccgacagac
     1501 aatagtataa atgttacatg tggtcctcct tatgaaacta atggccctaa aaccttttac
     1561 attttggtag tcagaagtgg aggttctttt gttacaaaat acaacaagac aaactgtcag
     1621 ttttatgtag ataatctcta ctattcaact gactatgagt ttctggtctc ttttcacaat
     1681 ggagtgtacg agggagattc agttataaga aatgagtcaa caaattttaa tgctaaagca
     1741 ctgattatat tcctggtgtt tctgattatt gtgacatcaa tagccttgct tgttgttttg
     1801 tataaaatct atgatctgcg caagaaaaga tccagcaatt tagatgaaca acaggaactc
     1861 gttgaaaggg atgatgaaaa gcagctgatg gatgtggagc caatccattc tgacattttg
     1921 ttggaaacat acaaaaggaa gattgctgat gagggcagac tgttcctggc tgaatttcag
     1981 agcattccac gggtattcag caagtttccc atcaaagatg cccgaaagcc ccacaatcag
     2041 aataaaaacc gttatgttga cattcttccc tatgattata accgtgtgga actctctgaa
     2101 ataaatggag atgcagggtc cacctacata aatgccagct acattgatgg cttcaaggaa
     2161 cccaggaaat acattgctgc acaagggccc cgggatgaga cagttgatga cttctggagg
     2221 atgatctggg agcaaaaggc cacagttatt gtcatggtca cacgatgtga agaaggaaac
     2281 aggaacaagt gcgcagaata ctggccaagc atggaggaag gcactcgggc tttcaaagat
     2341 attgttgtga caatcaatga ccacaaacga tgtcctgatt acatcattca gaagctgaac
     2401 gttgcacata aaaaagaaaa agcaactgga agagaagtga ctcatatcca attcaccagc
     2461 tggccagacc atggggttcc tgaagaccct cacctgctcc tcaaacttcg acggagagtt
     2521 aatgctttta gcaacttctt cagtggtccc attgtggtgc actgcagtgc tggtgttggg
     2581 cgtacaggta cctacattgg aattgatgcc atgctggaag gcctggaagc agagggcaaa
     2641 gtggatgtct atggttatgt tgtcaagcta aggcgacaga ggtgtctgat ggtgcaagtg
     2701 gaggcacagt atatcctgat tcatcaggct ttagtggaat acaatcagtt tggagaaaca
     2761 gaagtgaact tgtctgagtt acattcatgc ctacacaaca tgaagaagag agatccaccc
     2821 agtgacccct cccctctgga ggctgaatac cagagacttc cttcatacag gagttggagg
     2881 acacagcaca ttggaaatca agaagaaaat aagaagaaga acaggaattc taatgttgtt
     2941 ccatatgact ttaacagagt gccacttaag catgaactgg agatgagcaa agagagtgag
     3001 cctgaatcag atgagtcttc agatgatgac agtgactcag aagaaaccag caaatacatt
     3061 aatgcatcct ttgtgatgag ttactggaaa ccagaaatga tgattgctgc tcaggggcca
     3121 ctaaaagaaa cgatcggtga cttttggcag atgatattcc aaagaaaagt caaagttatt
     3181 gtgatgttga cagagttagt gaatggagac caggaagtct gtgctcagta ctggggcgaa
     3241 ggaaagcaga cttatggaga catggaagtg gagatgaaag acacaaacag agcctcagcc
     3301 tacactctcc gaacttttga gctgagacat tccaagagga aggagcccag aactgtgtac
     3361 cagtaccagt gtaccacatg gaaaggggaa gagctgcctg cagaacccaa agacctggtg
     3421 tctatgattc aggacctcaa acagaagctt cccaaggctt ccccagaagg gatgaagtat
     3481 cacaagcatg catccatcct cgtccactgc agagatggat cccagcagac agggttgttc
     3541 tgtgccttgt tcaatctctt ggaaagtgca gaaacagaag atgtggttga tgttttccaa
     3601 gtggtaaagt ctctacgcaa agcacggcct ggggtggtgt gcagctatga gcaataccag
     3661 ttcctctatg acatcatcgc cagcatctat cccgcccaga atggacaagt caagaaaaca
     3721 aacagccaag acaaaattga atttcataat gaagtggatg gaggcaagca ggatgctaac
     3781 tgtgtccgtc cagatggtcc tctgaataaa gcccaggaag acagcagagg ggtgggaacc
     3841 ccggagccta ccaatagtgc tgaggaacca gaacatgctg ccaatggttc tgcgagccca
     3901 gctccaaccc agagttcata ggaaaggagt catgtgggac aacgcagact ctcacattag
     3961 ttctttctat ttttctagac ctaatgaaag aacatggctg tgcagtggtt tatggaatct
     4021 gtgttcacct ttgccactgt ataaaaatat ttaagtttgt caaaacattt tgtacagttt
     4081 tatgcttatt ttaaaagtgt atctatgtca ttcagcagga atgtatatgt gagagagggt
     4141 gtctgtgtgt gtgagagtgt gtttatgtat gagtgactgt gtgtgtgcat gtttgtgcgt
     4201 gtgtatgaca tctaaatgtg attggagaat actttcaagc catttcaaat gctttcgaga
     4261 aacagtgtgc cttttctcct cttgaggaaa ctatacattt tatatctaaa ctgttaattt
     4321 gtttgaggga ttaatttttt aaaatcccat tgaaagtgga ttcagttgta agaataacaa
     4381 tgtgtaccat tctggaatga cctcaaggtg tcctccttgt cctgttgatg atcttgtagt
     4441 ttaagatgct ctttttggat atagataagc gtatgtaaga gtgctgtggg tgtgtacagc
     4501 tgatctggga cgtgaacaaa atcaacatgt gagacttatg ttccatatac tgtcatttca
     4561 tcactatctc ttaatgcata tttaatcaaa catgaaaatc tcaagggaga ctatttttgt
     4621 atccacatgg gaagtagaac attgcaagtc agttgctgtc tacacaatag ataaaaatta
     4681 ctagttaatg ctcttggtca tatcgatata tgctatgaac ctaaataatt gcccttagcc
     4741 aaatataatg tatgttaaaa acacatagaa taaaaacagg ggcatgaaaa cttgtttgta
     4801 ctgaatattt acataggtaa cctcgtacag ttagttctgt tatggaattc accatttatg
     4861 ggaaatgtaa aattgactat ggccatttcc tatgcttaag accatctttg acttgcatta
     4921 ctgtgtattt atcttgaatt tccccactgt tttgtttact cttactgaga tataatattg
     4981 ataaccataa taaactttca actattatct tctttgctta tgtggcgtgt gttacatgtt
     5041 tgtaattgac agtgaagcaa tttcttcttc aagctgagat tggttttccc attttgttca
     5101 ttgatgagaa aaatgaataa ttatcagata ggcgcatcag aaggggataa agaggactct
     5161 gttttctcac tagccactca cagatttcta tctcatgtca tctgggaaag gttctgttgc
     5221 tctttgctgg aaaacattgt ggaagtttgc agttctgatg ctgatgtacc ttcaggctgg
     5281 tttttatgtt gatttgtgat ttgtgatttg cttcagaatg ctgatcatct tcaatgatat
     5341 cttttggaac acagtttact tagtagctgt ttacttagca gcacatttgc aacagcatca
     5401 aaagctatgt tactataaaa tcagtgcgtg aagtctgatt tacattttgc tcaaggatct
     5461 gggtaaagtt ttctaccaag aatgttgagg actcatgaaa atgtgaagtt ctccaacttc
     5521 taaaattttt taggactttc aataaactat aaaattattc aaaatcac
//
