LOCUS       XM_006501149            5881 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus protein tyrosine phosphatase, non-receptor
            type 22 (lymphoid) (Ptpn22), transcript variant X4, mRNA.
ACCESSION   XM_006501149
VERSION     XM_006501149.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000069.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 8, 2019 this sequence version replaced XM_006501149.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5881
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="3"
     gene            1..5881
                     /gene="Ptpn22"
                     /gene_synonym="70zpep; PEP; Ptpn8"
                     /note="protein tyrosine phosphatase, non-receptor type 22
                     (lymphoid); Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 59 ESTs, 62 long SRA
                     reads, 3 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 5 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:19260"
                     /db_xref="MGI:MGI:107170"
     CDS             3261..5669
                     /gene="Ptpn22"
                     /gene_synonym="70zpep; PEP; Ptpn8"
                     /codon_start=1
                     /product="tyrosine-protein phosphatase non-receptor type
                     22 isoform X1"
                     /protein_id="XP_006501212.1"
                     /db_xref="GeneID:19260"
                     /db_xref="MGI:MGI:107170"
                     /translation="MDQREILQQLLKEAQKKKLNSEEFASEFLKLKRQSTKYKADKIY
                     PTTVAQRPKNIKKNRYKDILPYDHSLVELSLLTSDEDSSYINASFIKGVYGPKAYIAT
                     QGPLSTTLLDFWRMIWEYRILVIVMACMEFEMGKKKCERYWAEPGETQLQFGPFSISC
                     EAEKKKSDYKIRTLKAKFNNETRIIYQFHYKNWPDHDVPSSIDPILQLIWDMRCYQED
                     DCVPICIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQ
                     EQYELVYSAVLELFKRHMDVISDNHLGREIQAQCSIPEQSLTVEADSCPLDLPKNAMR
                     DVKTTNQHSKQGAEAESTGGSSLGLRTSTMNAEEELVLHSAKSSPSFNCLELNCGCNN
                     KAVITRNGQARASPVVGEPLQKYQSLDFGSMLFGSCPSALPINTADRYHNSKGPVKRT
                     KSTPFELIQQRKTNDLAVGDGFSCLESQLHEHYSLRELQVQRVAHVSSEELNYSLPGA
                     CDASCVPRHSPGALRVHLYTSLAEDPYFSSSPPNSADSKMSFDLPEKQDGATSPGALL
                     PASSTTSFFYSNPHDSLVMNTLTSFSPPLNQETAVEAPSRRTDDEIPPPLPERTPESF
                     IVVEEAGEPSPRVTESLPLVVTFGASPECSGTSEMKSHDSVGFTPSKNVKLRSPKSDR
                     HQDGSPPPPLPERTLESFFLADEDCIQAQAVQTSSTSYPETTENSTSSKQTLRTPGKS
                     FTRSKSLKIFRNMKKSVCNSSSPSKPTERVQPKNSSSFLNFGFGNRFSKPKGPRNPPS
                     AWNM"
ORIGIN      
        1 gttgggaagg gtagggaggt gggggaaggg aggggagaag agaaccaaca gaaagtctca
       61 gaatatttgc taaggaggtg actcagcagc aggagactca attccctcca cccatctggg
      121 attcttgttt gtttgtttgt tttcaggaca gggtttcatt gtgtcccttg ctgtcctaga
      181 actcactatg tagaccaggc tggccttgaa ctcacagaga tctgcctgcc tctacctcat
      241 gctgggatta aaggcatgta tcaccactgc ccagcccatc tgtaattcct gttccaggag
      301 attcaatgtc atttcaatgc catctctggc ttccctgggt accaggtatg catatggtat
      361 acatatagac atacacatgt aggcaaaaca tccatttata taaaattaaa taaaatgcct
      421 taacaccaac aagattaata accataggtt attagatgaa aatcccaatg tcagagatag
      481 gaattgccta cctctgttgt tagatagaaa gcacacacac acacacacta caagcaattg
      541 tcaatgtttc tgggtttcca tcagaactaa gatcttgctg ccaaaggtga catatgcttc
      601 ggttgcaaga catactgaaa tcaagctggt gctaagaagc ttcctttctg gtggctaact
      661 ggtgctctgc aggctgctgg ggaggctggt caccaacatt gttatttagc tgtggacatc
      721 tatacaataa cgcctactgg caatatgagc cctggggcaa tggcagcagg tctcttcagc
      781 agataaccag cagctttctg agtggatttg atgcccttgc catctacatg gtactataaa
      841 tctggttaaa tgctctggct gggggaaaag aaaaacaaaa caaaacaaca gcagcaacaa
      901 caaccaaaac ctctggctgg gaggtcatag gcccttatag ggcatccact gctgtcgttt
      961 tgcaaagcgg acgtgatgcg cctgtctaac tgccttctag ataactttct gtctatagag
     1021 tagtggtgct ttcagttttg gtcagagaac gtactgtctg cagtgatagg cagtgactgc
     1081 agagacaact ctggtcagag ttctgagaat aaaccactgg tgagtgctca ggaataaatg
     1141 ggacacctac atcacccctc cccaccccaa aacccaggga gcactcccag agaagggaca
     1201 gagagagatt atttattaac tttttctttt aacttttctt ttgttttgag acagaatttt
     1261 actgtgtaga tcaggctggt cttaaaactc acagaaatct gcctgcctct gtctcctgag
     1321 tgccaggatt taaaggccta tctttccagt gtaaaggcag gcgaaggcgg ttgaagaggt
     1381 ggggaatgct aatctctaag tgggacttgg gtgttacact cttgagctca tggaagctgt
     1441 gccactcgta gaggatccac acaaacttga gtttgtgtca actcaacact ctgtcgcgga
     1501 gggtaaggga ttcatggagt cccaccccag cctgaagatc tctatgccgg taatggttgg
     1561 cagggaaggg agagaagtca tcttcagtgt gagactctgg taagctatgc atgctcccct
     1621 aaactaccct aatgaagctc actgggattg aaaactaaaa aagacatgaa agtgggaggc
     1681 aggagatggt tggcaagagg agaggggtta ggtgtgaaga gaagagaggg taagactgaa
     1741 tgcgtagtgt aatcggaatg cattaactac aatatgaaaa tgtcatgtaa tccattatgt
     1801 gtgactaatg tatgataata atgttcctct ttctattttt atggcctaca cacacacaca
     1861 cacacacaca cacacacaca cacacacaca cacacactta aatctagatt ctctgtttaa
     1921 ggggaaaaaa catgtaatac ttgcctttct gagtctggct taaatttcat attttcatat
     1981 aattttattt atagttaact taggattttt aaagtattta acttttgaga cagtgtcttg
     2041 ctatatatag ttcagatagg cctgcacttt gtaaccattc tcctatctga gcctcctcag
     2101 tgctagtgtt acaagtatat tccattatac cctgaagaat gttgtattct ttttaaaaat
     2161 aaagcttccc catattttgt atgttttaaa atagtcaaat attgcatcat ttagagtagc
     2221 aagaaatttc ctgttgttgc tagacaagga taatctcaga gatttgtttt agtctcagga
     2281 aatattgctg aagaattatg gttcatttta atttgtgtga actacatttg aaattcttta
     2341 tgtgaaatac taacttcaaa ttgcctgcca agggttcaat gaagagggtg cagcgtgttt
     2401 tgtgttcaaa atcatgattt tctgaaggga gtttgaatag tgtaaaacca gaaagggttg
     2461 ctaatatctt aatagaggaa gtccaaacta cacctttccc agtttttttt tttaacttga
     2521 aactaatttt gtaacattct gtttactgaa cttcctcatt tgcaagggtt ttcacactga
     2581 attagatctt gagtggattt gtgcccatcg aagagaggat ttatgcaaac ggagatgtgg
     2641 aagcattctc tggaataacc tgccttgtta aggcactgat accacagatg tggacggctc
     2701 cctgaaacgc gatcttttct gagataggct ctgtaggatc aaaatgtcaa catgtcttca
     2761 tgaattcttc agcctctttc attcttcctc cctccccttc tgagagagag agagagagag
     2821 agagagagag cgctcacttt gtttctcagg tgtctcaaac tctgagactc aagtgatctt
     2881 gcagctgggg acagtcctga ggagctggga ctgcaccacc tctcctcaat tctctccaga
     2941 caggctgacc tagatagaat ctgtatggtt ctcagcaagc aatattttag ctttagttcc
     3001 gttttgtcct ttcgctgttt gctagcagtg cgttctgggg atattgtgct aactgcctcc
     3061 ccggtgcttc ccatcctgtg tagagctgta ctctcagtgt ttgcaaagct actggaggtc
     3121 tgaagaagta cagagaccaa cacttccctt aatgagggcc agtacttccc cagtcacggc
     3181 agggcatagg tgggcgtcac ccaggccttt ctgctcactg ggatgtgaaa agctgaactc
     3241 acagactctt gctctgcggc atggaccaaa gagaaattct gcagcaacta ctgaaagaag
     3301 cccagaaaaa gaaactcaac agtgaggagt ttgccagtga atttctgaag ctgaaaaggc
     3361 aatccaccaa gtacaaggcc gacaaaatct atcctacaac tgtggctcag aggcccaaga
     3421 atatcaagaa aaacagatac aaggatattt tgccctatga tcacagcctg gtagagctgt
     3481 ctctgttaac ttccgatgag gattccagtt atatcaatgc cagctttatt aagggtgtct
     3541 atggacccaa ggcttatatt gctacccagg gtcctttatc tacaactctc ctggacttct
     3601 ggaggatgat ttgggagtac cgcatcttgg tcattgtcat ggcatgtatg gagtttgaaa
     3661 tgggaaagaa aaaatgtgag cgttattggg ccgaaccagg agaaacgcag ctgcaatttg
     3721 gccccttttc tatatcctgt gaagctgaga aaaagaaatc tgattataaa atcaggactc
     3781 tgaaggccaa gttcaataat gaaactcgaa ttatttacca gtttcattat aagaattggc
     3841 cagaccatga tgtgccttca tctatagacc ctattcttca gctcatctgg gatatgcgtt
     3901 gttaccaaga agatgactgt gttcctatat gcattcactg cagtgccggc tgcggaagga
     3961 caggtgtcat ttgtgctgtt gattatacat ggatgctgct gaaagatggg ataattccta
     4021 agaacttcag tgtttttaat ttgattcagg agatgcgaac acagaggcct tcgctagttc
     4081 aaactcagga acagtacgaa ctggtctaca gtgctgtgtt agagctgttt aagaggcaca
     4141 tggatgttat ctctgataat caccttggaa gagagattca agcacaatgc tcaattcctg
     4201 aacaaagcct cacggtagaa gctgactctt gtcctctgga tttaccaaaa aacgccatga
     4261 gggatgtgaa aacgacaaac cagcatagca aacaaggggc tgaagcggag agcactggag
     4321 ggtcttccct tggccttagg acttctacga tgaatgccga ggaagagttg gttttgcact
     4381 cggctaaatc aagcccttct tttaactgtt tagagctaaa ctgcgggtgt aacaacaagg
     4441 ctgtcataac caggaacggg caggcaaggg cttctccagt cgtgggagag ccccttcaga
     4501 agtatcaaag tctggatttt ggttccatgt tgtttgggtc gtgtcctagt gctctgccca
     4561 taaacacagc ggacaggtat cacaattcaa aggggccggt aaaacggacc aaatcaactc
     4621 cctttgaact gattcagcag agaaaaacaa atgacttggc cgtgggagac ggtttttcat
     4681 gcctggaatc tcagctgcat gagcattaca gtctcaggga gctgcaggtg caaagagtgg
     4741 cccatgtttc ttcagaagag ctgaattatt cactgcctgg tgcctgtgat gcgtcgtgtg
     4801 tgccccggca cagccccggc gctttgagag tgcatctgta cacatcttta gcggaagatc
     4861 cttatttttc atcatcccct ccgaatagtg ctgattcgaa gatgtctttt gatctgcctg
     4921 agaaacagga tggagccact tcccctggcg ctctattgcc agcctcttct acaacctcct
     4981 tcttttatag caacccacac gactccctag tgatgaacac tctgaccagc ttttccccac
     5041 cgttaaacca agagacagct gtagaagctc cttctcggag gacagatgat gaaatccccc
     5101 cgccactccc tgaacggaca cccgagtctt ttattgtggt tgaggaagcc ggagagccct
     5161 caccacgtgt taccgaatcc ttacctctgg tggtaacatt tggagcatca ccagaatgca
     5221 gtgggacatc tgaaatgaag agccatgact ctgtagggtt tacaccaagc aagaatgtga
     5281 aactccgaag tcccaaatca gatcgacatc aggatggttc tcctccacct cctctcccag
     5341 aaagaactct agagtccttc tttcttgctg atgaggactg tatacaggcc caagccgtgc
     5401 aaacttcttc tactagctat cctgaaacca cagagaactc cacatcttct aaacaaacat
     5461 tgaggacccc tggaaaaagt ttcacaagga gtaagagttt gaagattttt cgaaatatga
     5521 aaaaaagtgt ttgtaattct tcctcaccaa gcaagcctac agaacgtgtt cagccaaaaa
     5581 attccagctc ctttctgaat tttggtttcg gaaatcgttt ttcaaaaccc aaaggaccaa
     5641 ggaacccgcc atcagcttgg aatatgtaac gcacctctgg atttataaga atatttgtta
     5701 aaattgtacc tgcagataaa gctacttgaa tactgctata ataataatat cagtaatgag
     5761 gatatatttt gtcaatagtc ttgaaaagga aagcaatatg tgacaaactt ccagcaaact
     5821 tgtattttca tattccttat atttcactgg gaactgccaa taaagtttgt acttcagttt
     5881 a
//
