LOCUS       XM_006501148            5993 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus protein tyrosine phosphatase, non-receptor
            type 22 (lymphoid) (Ptpn22), transcript variant X2, mRNA.
ACCESSION   XM_006501148
VERSION     XM_006501148.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000069.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 8, 2019 this sequence version replaced XM_006501148.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5993
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="3"
     gene            1..5993
                     /gene="Ptpn22"
                     /gene_synonym="70zpep; PEP; Ptpn8"
                     /note="protein tyrosine phosphatase, non-receptor type 22
                     (lymphoid); Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 59 ESTs, 62 long SRA
                     reads, 3 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 8 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:19260"
                     /db_xref="MGI:MGI:107170"
     CDS             3373..5781
                     /gene="Ptpn22"
                     /gene_synonym="70zpep; PEP; Ptpn8"
                     /codon_start=1
                     /product="tyrosine-protein phosphatase non-receptor type
                     22 isoform X1"
                     /protein_id="XP_006501211.1"
                     /db_xref="GeneID:19260"
                     /db_xref="MGI:MGI:107170"
                     /translation="MDQREILQQLLKEAQKKKLNSEEFASEFLKLKRQSTKYKADKIY
                     PTTVAQRPKNIKKNRYKDILPYDHSLVELSLLTSDEDSSYINASFIKGVYGPKAYIAT
                     QGPLSTTLLDFWRMIWEYRILVIVMACMEFEMGKKKCERYWAEPGETQLQFGPFSISC
                     EAEKKKSDYKIRTLKAKFNNETRIIYQFHYKNWPDHDVPSSIDPILQLIWDMRCYQED
                     DCVPICIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQ
                     EQYELVYSAVLELFKRHMDVISDNHLGREIQAQCSIPEQSLTVEADSCPLDLPKNAMR
                     DVKTTNQHSKQGAEAESTGGSSLGLRTSTMNAEEELVLHSAKSSPSFNCLELNCGCNN
                     KAVITRNGQARASPVVGEPLQKYQSLDFGSMLFGSCPSALPINTADRYHNSKGPVKRT
                     KSTPFELIQQRKTNDLAVGDGFSCLESQLHEHYSLRELQVQRVAHVSSEELNYSLPGA
                     CDASCVPRHSPGALRVHLYTSLAEDPYFSSSPPNSADSKMSFDLPEKQDGATSPGALL
                     PASSTTSFFYSNPHDSLVMNTLTSFSPPLNQETAVEAPSRRTDDEIPPPLPERTPESF
                     IVVEEAGEPSPRVTESLPLVVTFGASPECSGTSEMKSHDSVGFTPSKNVKLRSPKSDR
                     HQDGSPPPPLPERTLESFFLADEDCIQAQAVQTSSTSYPETTENSTSSKQTLRTPGKS
                     FTRSKSLKIFRNMKKSVCNSSSPSKPTERVQPKNSSSFLNFGFGNRFSKPKGPRNPPS
                     AWNM"
ORIGIN      
        1 gttgggaagg gtagggaggt gggggaaggg aggggagaag agaaccaaca gaaagtctca
       61 gaatatttgc taaggaggtg actcagcagc aggagactca attccctcca cccatctggg
      121 attcttgttt gtttgtttgt tttcaggaca gggtttcatt gtgtcccttg ctgtcctaga
      181 actcactatg tagaccaggc tggccttgaa ctcacagaga tctgcctgcc tctacctcat
      241 gctgggatta aaggcatgta tcaccactgc ccagcccatc tgtaattcct gttccaggag
      301 attcaatgtc atttcaatgc catctctggc ttccctgggt accaggtatg catatggtat
      361 acatatagac atacacatgt aggcaaaaca tccatttata taaaattaaa taaaatgcct
      421 taacaccaac aagattaata accataggtt attagatgaa aatcccaatg tcagagatag
      481 gaattgccta cctctgttgt tagatagaaa gcacacacac acacacacta caagcaattg
      541 tcaatgtttc tgggtttcca tcagaactaa gatcttgctg ccaaaggtga catatgcttc
      601 ggttgcaaga catactgaaa tcaagctggt gctaagaagc ttcctttctg gtggctaact
      661 ggtgctctgc aggctgctgg ggaggctggt caccaacatt gttatttagc tgtggacatc
      721 tatacaataa cgcctactgg caatatgagc cctggggcaa tggcagcagg tctcttcagc
      781 agataaccag cagctttctg agtggatttg atgcccttgc catctacatg gtactataaa
      841 tctggttaaa tgctctggct gggggaaaag aaaaacaaaa caaaacaaca gcagcaacaa
      901 caaccaaaac ctctggctgg gaggtcatag gcccttatag ggcatccact gctgtcgttt
      961 tgcaaagcgg acgtgatgcg cctgtctaac tgccttctag ataactttct gtctatagag
     1021 tagtggtgct ttcagttttg gtcagagaac gtactgtctg cagtgatagg cagtgactgc
     1081 agagacaact ctggtcagag ttctgagaat aaaccactgg tgagtgctca ggaataaatg
     1141 ggacacctac atcacccctc cccaccccaa aacccaggga gcactcccag agaagggaca
     1201 gagagagatt atttattaac tttttctttt aacttttctt ttgttttgag acagaatttt
     1261 actgtgtaga tcaggctggt cttaaaactc acagaaatct gcctgcctct gtctcctgag
     1321 tgccaggatt taaaggccta tctttccagt gtaaaggcag gcgaaggcgg ttgaagaggt
     1381 ggggaatgct aatctctaag tgggacttgg gtgttacact cttgagctca tggaagctgt
     1441 gccactcgta gaggatccac acaaacttga gtttgtgtca actcaacact ctgtcgcgga
     1501 gggtaaggga ttcatggagt cccaccccag cctgaagatc tctatgccgg taatggttgg
     1561 cagggaaggg agagaagtca tcttcagtgt gagactctgg taagctatgc atgctcccct
     1621 aaactaccct aatgaagctc actgggattg aaaactaaaa aagacatgaa agtgggaggc
     1681 aggagatggt tggcaagagg agaggggtta ggtgtgaaga gaagagaggg taagactgaa
     1741 tgcgtagtgt aatcggaatg cattaactac aatatgaaaa tgtcatgtaa tccattatgt
     1801 gtgactaatg tatgataata atgttcctct ttctattttt atggcctaca cacacacaca
     1861 cacacacaca cacacacaca cacacacaca cacacactta aatctagatt ctctgtttaa
     1921 ggggaaaaaa catgtaatac ttgcctttct gagtctggct taaatttcat attttcatat
     1981 aattttattt atagttaact taggattttt aaagtattta acttttgaga cagtgtcttg
     2041 ctatatatag ttcagatagg cctgcacttt gtaaccattc tcctatctga gcctcctcag
     2101 tgctagtgtt acaagtatat tccattatac cctgaagaat gttgtattct ttttaaaaat
     2161 aaagcttccc catattttgt atgttttaaa atagtcaaat attgcatcat ttagagtagc
     2221 aagaaatttc ctgttgttgc tagacaagga taatctcaga gatttgtttt agtctcagga
     2281 aatattgctg aagaattatg gttcatttta atttgtgtga actacatttg aaattcttta
     2341 tgtgaaatac taacttcaaa ttgcctgcca agggttcaat gaagagggtg cagcgtgttt
     2401 tgtgttcaaa atcatgattt tctgaaggga gtttgaatag tgtaaaacca gaaagggttg
     2461 ctaatatctt aatagaggaa gtccaaacta cacctttccc agtttttttt tttaacttga
     2521 aactaatttt gtaacattct gtttactgaa cttcctcatt tgcaagggtt ttcacactga
     2581 attagatctt gagtggattt gtgcccatcg aagagaggat ttatgcaaac ggagatgtgg
     2641 aagcattctc tggaataacc tgccttgtta aggcactgat accacagatg tggacggctc
     2701 cctgaaacgc gatcttttct gagataggct ctgtaggatc aaaatgtcaa catgtcttca
     2761 tgaattcttc agcctctttc attcttcctc cctccccttc tgagagagag agagagagag
     2821 agagagagag cgctcacttt gtttctcagg tgtctcaaac tctgagactc aagtgatctt
     2881 gcagctgggg acagtcctga ggagctggga ctgcaccacc tctcctcaat tctctccaga
     2941 caggctgacc tagatagaat ctgtatggtt ctcagcaagc aatattttag ctttagttcc
     3001 gttttgtcct ttcgctgttt gctagcagtg cgttctgggg atattgtgct aactgcctcc
     3061 ccggtgcttc ccatcctgtg tagagctgta ctctcagtgt ttgcaaagct actggaggtc
     3121 tgaagaagta cagagaccaa cacttccctt aatgagggcc agtacttccc cagtcacggg
     3181 tgagatggac catcagaagc agtggacttt gcttcctcta aaagaaaaac gtgaggttta
     3241 taatggaagc ttgacaaatt ctgaaacaaa atgcccgctt gatgagcaga gcagggcata
     3301 ggtgggcgtc acccaggcct ttctgctcac tgggatgtga aaagctgaac tcacagactc
     3361 ttgctctgcg gcatggacca aagagaaatt ctgcagcaac tactgaaaga agcccagaaa
     3421 aagaaactca acagtgagga gtttgccagt gaatttctga agctgaaaag gcaatccacc
     3481 aagtacaagg ccgacaaaat ctatcctaca actgtggctc agaggcccaa gaatatcaag
     3541 aaaaacagat acaaggatat tttgccctat gatcacagcc tggtagagct gtctctgtta
     3601 acttccgatg aggattccag ttatatcaat gccagcttta ttaagggtgt ctatggaccc
     3661 aaggcttata ttgctaccca gggtccttta tctacaactc tcctggactt ctggaggatg
     3721 atttgggagt accgcatctt ggtcattgtc atggcatgta tggagtttga aatgggaaag
     3781 aaaaaatgtg agcgttattg ggccgaacca ggagaaacgc agctgcaatt tggccccttt
     3841 tctatatcct gtgaagctga gaaaaagaaa tctgattata aaatcaggac tctgaaggcc
     3901 aagttcaata atgaaactcg aattatttac cagtttcatt ataagaattg gccagaccat
     3961 gatgtgcctt catctataga ccctattctt cagctcatct gggatatgcg ttgttaccaa
     4021 gaagatgact gtgttcctat atgcattcac tgcagtgccg gctgcggaag gacaggtgtc
     4081 atttgtgctg ttgattatac atggatgctg ctgaaagatg ggataattcc taagaacttc
     4141 agtgttttta atttgattca ggagatgcga acacagaggc cttcgctagt tcaaactcag
     4201 gaacagtacg aactggtcta cagtgctgtg ttagagctgt ttaagaggca catggatgtt
     4261 atctctgata atcaccttgg aagagagatt caagcacaat gctcaattcc tgaacaaagc
     4321 ctcacggtag aagctgactc ttgtcctctg gatttaccaa aaaacgccat gagggatgtg
     4381 aaaacgacaa accagcatag caaacaaggg gctgaagcgg agagcactgg agggtcttcc
     4441 cttggcctta ggacttctac gatgaatgcc gaggaagagt tggttttgca ctcggctaaa
     4501 tcaagccctt cttttaactg tttagagcta aactgcgggt gtaacaacaa ggctgtcata
     4561 accaggaacg ggcaggcaag ggcttctcca gtcgtgggag agccccttca gaagtatcaa
     4621 agtctggatt ttggttccat gttgtttggg tcgtgtccta gtgctctgcc cataaacaca
     4681 gcggacaggt atcacaattc aaaggggccg gtaaaacgga ccaaatcaac tccctttgaa
     4741 ctgattcagc agagaaaaac aaatgacttg gccgtgggag acggtttttc atgcctggaa
     4801 tctcagctgc atgagcatta cagtctcagg gagctgcagg tgcaaagagt ggcccatgtt
     4861 tcttcagaag agctgaatta ttcactgcct ggtgcctgtg atgcgtcgtg tgtgccccgg
     4921 cacagccccg gcgctttgag agtgcatctg tacacatctt tagcggaaga tccttatttt
     4981 tcatcatccc ctccgaatag tgctgattcg aagatgtctt ttgatctgcc tgagaaacag
     5041 gatggagcca cttcccctgg cgctctattg ccagcctctt ctacaacctc cttcttttat
     5101 agcaacccac acgactccct agtgatgaac actctgacca gcttttcccc accgttaaac
     5161 caagagacag ctgtagaagc tccttctcgg aggacagatg atgaaatccc cccgccactc
     5221 cctgaacgga cacccgagtc ttttattgtg gttgaggaag ccggagagcc ctcaccacgt
     5281 gttaccgaat ccttacctct ggtggtaaca tttggagcat caccagaatg cagtgggaca
     5341 tctgaaatga agagccatga ctctgtaggg tttacaccaa gcaagaatgt gaaactccga
     5401 agtcccaaat cagatcgaca tcaggatggt tctcctccac ctcctctccc agaaagaact
     5461 ctagagtcct tctttcttgc tgatgaggac tgtatacagg cccaagccgt gcaaacttct
     5521 tctactagct atcctgaaac cacagagaac tccacatctt ctaaacaaac attgaggacc
     5581 cctggaaaaa gtttcacaag gagtaagagt ttgaagattt ttcgaaatat gaaaaaaagt
     5641 gtttgtaatt cttcctcacc aagcaagcct acagaacgtg ttcagccaaa aaattccagc
     5701 tcctttctga attttggttt cggaaatcgt ttttcaaaac ccaaaggacc aaggaacccg
     5761 ccatcagctt ggaatatgta acgcacctct ggatttataa gaatatttgt taaaattgta
     5821 cctgcagata aagctacttg aatactgcta taataataat atcagtaatg aggatatatt
     5881 ttgtcaatag tcttgaaaag gaaagcaata tgtgacaaac ttccagcaaa cttgtatttt
     5941 catattcctt atatttcact gggaactgcc aataaagttt gtacttcagt tta
//
