LOCUS       NM_133949               1764 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus prostate tumor over expressed gene 1 (Ptov1), mRNA.
ACCESSION   NM_133949
VERSION     NM_133949.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1764)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1764)
  AUTHORS   Yao,Y.W., Shi,Y., Jia,Z.F., Jiang,Y.H., Gu,Z., Wang,J., Aljofan,M.
            and Sun,Z.G.
  TITLE     PTOV1 is associated with UCH-L1 and in response to estrogen stimuli
            during the mouse oocyte development
  JOURNAL   Histochem Cell Biol 136 (2), 205-215 (2011)
   PUBMED   21678139
  REMARK    GeneRIF: PTOV1 is associated with UCH-L1 and in response to
            estrogen stimuli during the mouse oocyte development
REFERENCE   3  (bases 1 to 1764)
  AUTHORS   Benedit,P., Paciucci,R., Thomson,T.M., Valeri,M., Nadal,M.,
            Caceres,C., de Torres,I., Estivill,X., Lozano,J.J., Morote,J. and
            Reventos,J.
  TITLE     PTOV1, a novel protein overexpressed in prostate cancer containing
            a new class of protein homology blocks
  JOURNAL   Oncogene 20 (12), 1455-1464 (2001)
   PUBMED   11313889
REFERENCE   4  (bases 1 to 1764)
  AUTHORS   Wertz,K. and Herrmann,B.G.
  TITLE     Large-scale screen for genes involved in gonad development
  JOURNAL   Mech Dev 98 (1-2), 51-70 (2000)
   PUBMED   11044607
REFERENCE   5  (bases 1 to 1764)
  AUTHORS   Kambouris,M., Triarhou,L.C., Dlouhy,S.R., Sangameswaran,L., Luo,F.,
            Ghetti,B. and Hodes,M.E.
  TITLE     Novel cDNA clones obtained by antibody screening of a mouse
            cerebellar cDNA expression library
  JOURNAL   Brain Res Mol Brain Res 25 (3-4), 183-191 (1994)
   PUBMED   7808216
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158231.2.
            
            On Jul 4, 2018 this sequence version replaced NM_133949.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC008543.1, SRR7652917.1220966.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-318               AC158231.2         142050-142367       c
            319-456             AC158231.2         140074-140211       c
            457-539             AC158231.2         139892-139974       c
            540-597             AC158231.2         139759-139816       c
            598-705             AC158231.2         139509-139616       c
            706-861             AC158231.2         138171-138326       c
            862-951             AC158231.2         137612-137701       c
            952-1025            AC158231.2         137461-137534       c
            1026-1083           AC158231.2         137311-137368       c
            1084-1188           AC158231.2         137082-137186       c
            1189-1386           AC158231.2         136234-136431       c
            1387-1764           AC158231.2         135766-136143       c
FEATURES             Location/Qualifiers
     source          1..1764
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.94 cM"
     gene            1..1764
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /note="prostate tumor over expressed gene 1"
                     /db_xref="GeneID:84113"
                     /db_xref="MGI:MGI:1933946"
     exon            1..318
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..1398
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /note="granule cell antiserum positive 3"
                     /codon_start=1
                     /product="prostate tumor-overexpressed gene 1 protein
                     homolog"
                     /protein_id="NP_598710.1"
                     /db_xref="CCDS:CCDS21219.1"
                     /db_xref="GeneID:84113"
                     /db_xref="MGI:MGI:1933946"
                     /translation="MVRPRRAPHRSGAGGPLGGRGRPPRPLVVRAVRSRSWPGGPRGP
                     QPPRIRARSAPPMEGARVFGALGPIGPSSPGLTLGGLAVNEHRLSNKLLAWSGVLEWQ
                     EKRRPFSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNS
                     QLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLI
                     PYDQSGFVNAIRQVITTRKQAVGPGGVHSGPVQIVNNKFLAWSGVMEWQEPRPEPNSR
                     SKRWLPSHVYVNQGEILRTDQWPRRLFMQLIPQQLLTTLVPLFRNSRLVQFHFTKDME
                     TLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQSNFVNGIRR
                     VIANQQQVLQRSLEQEQQQRGMGG"
     exon            319..456
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            457..539
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            540..597
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            598..705
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            706..861
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            862..951
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1025
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1083
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..1188
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1386
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1387..1764
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1745..1750
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /note="hexamer: AATAAA"
     polyA_site      1763
                     /gene="Ptov1"
                     /gene_synonym="1110030G05Rik; Gcap3"
                     /note="major polyA site"
ORIGIN      
        1 gttcgctgca gtggttcggc cgcggcgacc cctcagcggc gcgtcccccg ccgcggtccc
       61 gctccgcttc tccccgaagc cgcgcgcccg cgcctgtcgg tcggcggacc cgcagccccc
      121 cgtgaggccc acggcctccc acccgccatg gtccgcccgc gccgtgcccc gcaccgctcc
      181 ggcgccgggg gccccctcgg aggtcgtggc cggccaccgc ggcccctggt cgtccgcgcc
      241 gtgcgctcac gttcctggcc tggcggtcct cgaggcccgc agccaccgcg gatccgggct
      301 cgttcggccc ctcccatgga gggtgctcga gtctttggag ccctggggcc tatcgggccc
      361 tcttcacctg ggctgactct tgggggcctc gcagtgaacg agcaccggct cagcaacaaa
      421 ctgctggcct ggagtggcgt gctggagtgg caggagaagc gtagaccctt ctcggactcc
      481 acagccaagc tgaaacgcac cctgccctgc caggcctatg tgaaccaggg cgagaacctg
      541 gagacggacc agtggcccca gaagttgatc atgcagctca tcccacagca gctgctgacc
      601 acactgggtc ccctgttccg aaactctcag ctggcccagt tccacttcac caacagagac
      661 tgtgactccc tcaagggcct ctgccgcatc atgggcaatg gcttcgcagg ctgcatgctc
      721 ttcccccaca tttctccttg cgaggtgcgc gtgctcatgc tcctgtactc gtctaagaag
      781 aagatcttca tgggcctcat cccctacgac cagagcggct tcgtcaacgc catacgacag
      841 gtcatcacca cccgcaaaca ggccgtgggc cccgggggtg tacactctgg acctgttcag
      901 attgtcaaca acaaattctt ggcatggagt ggtgtcatgg agtggcagga gcccaggcct
      961 gagcccaaca gccggtccaa gaggtggctg ccatcccacg tctatgtgaa ccaaggggag
     1021 atcctgagaa cagaccagtg gcctcggagg ctcttcatgc agctcattcc gcagcagttg
     1081 ctgaccaccc tcgtgccact gttccggaat tcacgcctgg tacagttcca cttcactaag
     1141 gacatggaga ctctgaagag cctttgccgg atcatggaca atggcttcgc gggctgcgtg
     1201 cacttctcct acaaggcatc gtgtgaggtg cgtgtgctca tgctcctgta ctcctcggag
     1261 aagaagatct tcatcggcct catcccgcac gaccagagca actttgtcaa cggcatccgt
     1321 cgcgtcatcg ccaaccagca gcaggtcctg cagcgaagcc tggagcagga gcagcagcag
     1381 cgagggatgg gtggctagag gatgcctggg ctgggcgggc cacagtccca gacgaggccc
     1441 cagtggagac tggtgagcag cactgtgtcc gtgggaagca gcagggtggc cctggcctga
     1501 gagagacctg ctgcatgcgt cactgcctcc tgctaccaat atccctgggg aggaatgggt
     1561 gccagggcca cagcttaata ctggggagta gggtgcagtt tcactagtag aagccacccc
     1621 tcctcctgcc tcccaggtca gctgcttctg agcaggggct cctggcgact gtacctgccc
     1681 agcaacctgg aggacagcgt cctgaggtct cccaaggatg gtccttgccc ctgtatgttt
     1741 ccctaataaa gccttttaac ccac
//
