LOCUS       XM_036159144            7247 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus PTK2 protein tyrosine kinase 2 (Ptk2),
            transcript variant X31, mRNA.
ACCESSION   XM_036159144
VERSION     XM_036159144.1
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000081.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7247
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="15"
     gene            1..7247
                     /gene="Ptk2"
                     /gene_synonym="Fadk; FADK 1; FAK; FRNK; p125FAK"
                     /note="PTK2 protein tyrosine kinase 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 mRNAs, 39 ESTs, 2100 long SRA reads, 12 Proteins,
                     and 86% coverage of the annotated genomic feature by
                     RNAseq alignments, including 15 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:14083"
                     /db_xref="MGI:MGI:95481"
     CDS             3026..6301
                     /gene="Ptk2"
                     /gene_synonym="Fadk; FADK 1; FAK; FRNK; p125FAK"
                     /codon_start=1
                     /product="focal adhesion kinase 1 isoform X16"
                     /protein_id="XP_036015037.1"
                     /db_xref="GeneID:14083"
                     /db_xref="MGI:MGI:95481"
                     /translation="MLLERAGQEALRPTGAVCMEKSGCSPFPVCWAKEYDRYLASSKR
                     MAAAYLDPNLNHTPSSSTKTHLGTGMERSPGAMERVLKVFHYFESSSEPTTWASIIRH
                     GDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHP
                     PEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMQEIADQVDQEIALKLGCL
                     EIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFA
                     NLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNP
                     THLADFNQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYC
                     RLVNGATQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSDEISGDETDDYAEI
                     IDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALAV
                     AIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRS
                     FLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL
                     SRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQG
                     VKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEE
                     KVQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNH
                     YQVSGYPGSHGIPAMAGSIYQGQASLLDQTELWNHRPQEMSMWQPSVEDSAALDLRGM
                     GQVLPPHLMEERLIRQQQEMEEDQRWLEKEERFLTGNQHIYQPVGKPDPAAPPKKPPR
                     PGAPGHLSNLSSISSPADSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVK
                     AVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPALPASTHREIEMAQKLLN
                     SDLGELISKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQT
                     RPH"
ORIGIN      
        1 tggctcagca tagcctcgct cacaagccta gaggctggca gcttgctgct agggtcccat
       61 gtggcttgct taggaggcca actttcactc ttttgtcagg gttaagaaga aacagctttg
      121 ggtatcctgt gatcagcacc atgtcaccta tgatgtatca ctgtgatcaa agcaaagtat
      181 gagacttgtg cagattcaag gggtgaaaac tcagattctg cctcctgttg ggaggcctgt
      241 caaagactcg gtgacccttt tcagtccact gcagagtgct acctctcctc acaaagccat
      301 ttttgatgca aacccccttt tgtgtcacca ctccaagccc ctccccccta tccttctgat
      361 actttaaata ataatctctc attttacacc atgcaaagct tcattcaccc actcaacaaa
      421 tatttactgt gtgccaggga ctgcctgggg aacaaaacaa agtccctgtt ctatgaatct
      481 agaagtccag agcagagaca atcgagagac ggacaagagc agtgttgaac tgttctgaac
      541 aataggtttg gagacaacag ggtaagcagg caaggagcct agatgggagc acactcagca
      601 gggcaatggg tggctcgggt ttcaaagtag tcagctgaca ttaccgaagt gacaactaac
      661 atggggccga agaaaaagtg ctagaggtga cacagagaca taatcccttc taattttaag
      721 tgcagaaaaa cactataggt tggctattgt gacataatct gtaatcccag caccagaaga
      781 tggaagtaga aagagctgga gttcaaggct atcctcagct acacagaaag ttttagtaca
      841 gcctgggcta catgaaacta tatctcaaac aaacaaacaa acaaacaaga acgaaacaaa
      901 ataaaactag agctagaggg atccctcagt ggttaagagc acttgtcttt ggaaaggtcc
      961 tagattctat tcccacacca acatggtggc tggctcacga ctatctctaa tttcagaaga
     1021 gatccaatac cctcttctga cctccacgtg caccaggcat gtgtgtgata cccatatata
     1081 cattcaagga aaacacacaa gtacaataaa ataaataaat ctgggagaga aaaaaaaacc
     1141 cccaaacata accaccacta ctagttcaaa tccaagttta atacacttca ttaaaaaaaa
     1201 caataaaaaa gaaacactaa aatatggcaa aatctcgaca actcaaagcg ttttattata
     1261 cctgagtaaa ttacagctcc caggtatgta gtggttggtg gttctgtgtt cacctttcac
     1321 tgcctgtcct gcttgctcgt tggcttgtgg tcgaagatca aaatgacacc attaaaaatg
     1381 aaagttcccc gcttctggtt tcatttccta ccgcaaggat gccagtgatt tttttccttt
     1441 ttttttttca gagatcacaa atcagtcacc acttcctgct taagactctc cgtagggttg
     1501 ctgcacaaaa acaaactcag ggaaactagg cacggctcgg aaggacaggg ccacctgctt
     1561 gattcaggca aaggtgtccc cccagtctca cgtttcgtgg taagttccgc gctggaactg
     1621 gctcttaagc cagcagccat ccacagtggc tctcccgttc tggccctcct gtccacccag
     1681 tgtccccgaa aggcttcccc agtcttaaga tctacagggg ctgcgggaag gggctggaat
     1741 gtgagtggcc ccaggcactc ctaaacgatc tttcggaccg tcttcagaga tccattaaaa
     1801 tactctctgt gcctcagttt ccccatctac agaaagccca tgaacctcta ttgaagcggt
     1861 gaagcctgga gaagatcagg gccggcgtgt gtgcggctaa ggatctcctg tgaccgtgag
     1921 ggacccaggc ctagtccgca gaccctgggg cggccacagg ggccacctcg tcatcccgga
     1981 acagcgctat ccgcggacga cgccacgccc gcacagctgg gatacacttt actaggagcc
     2041 gggcgcgccg gactgctctg cgcaggcgcg gtccgcactg cgcaggcgta gagctctgcg
     2101 ctgaggtgag gcattgcgcg ccgcgaggtg tgggcgcgcg ctccccagcc acggcgcacg
     2161 cgcgggcccg cgccgactca gcacggcccg agggcgcgag cccgccgtca ccgctaccgc
     2221 cgccggccgg accgccgtgc gcccggcgtg cgcgtgggag agagcacggc tgccggtgcc
     2281 ggcgccgccc cgctgccttc tatctgcctc agcctcgcgc gcccagtggt ggccggtctc
     2341 tgggctacaa tgtaaagagg aaacagatac taggaatatt ttttagaaca gctatttgat
     2401 ttcttctcaa agtcactgct gccttctgag ttttcctctt gctcctgtga gtaaggggag
     2461 gaatctgttc tatgtctgcc tgtgccagat gtgagagctc tgtgtcatct gtggtatcat
     2521 gcctgtttga cccaagacaa ggtctcacta tgaagcactg actgacctgg aacttgttat
     2581 gtagactagg ctggtttata acccaagaga tcttcctgac cacgcctagg aatgaagttt
     2641 ttaaattctt gtcataaagt agttagcgcc ttctccagct tcctgcagca tgacagaaga
     2701 gagatacagc agttgtttca aagctggcag ggaggtgaac agtggtccta ccagcacttt
     2761 tgggagattg ttgtactagg aagctgcttg tttgttgtct ttgctttcag aagattgcgg
     2821 aagcagaaga ttcagtaact gagaggccac cgtggagctg ctggaaactg ttacagaagg
     2881 agcacctctc aaaccgtgct tcaggctctg agaaaaggag cacaggggaa attagtcttg
     2941 ctttggatcc aagcaaatgc tgtcggagca atgaactggg actttgtgtg cggactcctg
     3001 gcttgatctt gataggattg ggtgtatgtt gttggaacgg gcaggccaag aggccctgag
     3061 acctacaggt gccgtctgta tggagaaaag cggctgtagt ccatttccag tgtgttgggc
     3121 taaagaatat gacagatacc tagcatctag caaaagaatg gcagctgctt atcttgaccc
     3181 aaacttgaat cacacaccaa gttcgagtac taagactcac ctgggtactg gcatggaacg
     3241 gtcccctggt gcaatggaac gagtattaaa ggtctttcat tattttgaaa gcagtagtga
     3301 gccaaccacc tgggccagta ttatcaggca tggagatgct actgatgtca ggggcatcat
     3361 tcagaagata gtggacagtc acaaagtaaa gcacgtggcc tgctatggat ttcgcctcag
     3421 tcacctgcga tcggaggagg tgcactggct gcacgtggac atgggtgtct ccagtgtgag
     3481 ggagaaatat gaactcgccc acccaccaga ggagtggaaa tatgagttga gaattcgtta
     3541 cttgccaaaa ggatttctaa accagtttac tgaagataag ccaacattga atttcttcta
     3601 tcaacaggtg aagagtgact acatgcaaga aatagctgat caagtagacc aagaaatagc
     3661 tttgaagttg ggttgtttgg aaattaggcg atcctattgg gagatgaggg gtaatgccct
     3721 agagaagaag tccaactatg aagtattaga aaaagatgtt ggtttaaagc gattttttcc
     3781 taagagttta ctggattctg tcaaggccaa aacactaaga aagctgatcc agcaaacatt
     3841 caggcagttt gccaacctta atagagaaga aagcatcctg aaattctttg agattctttc
     3901 tcctgtgtac agatttgaca aagagtgctt caagtgtgcc cttgggtcaa gttggatcat
     3961 ttctgtggaa ttggcaatcg gcccagaaga agggatcagt tacctgacag acaaaggctg
     4021 caatcccaca cacctagcag actttaacca agtgcagacc atccagtact caaacagtga
     4081 agacaaagac aggaaaggaa tgctacaact caaaatcgct ggtgctcctg agcctctgac
     4141 cgtgacggca ccatccctaa ccattgccga gaacatggcc gacctgattg atggatactg
     4201 ccggctggtg aatggagcca cacaatcttt catcatcaga ccccagaaag aaggtgaacg
     4261 ggcgttgcca tcaataccaa agttggccaa cagtgaaaag caaggcatgc ggacacatgc
     4321 agtctctgtg tcagatgaaa ttagtgggga cgagacagat gactatgcag agatcatcga
     4381 tgaggaagac acatacacca tgccctcgaa aagctatgga atagatgaag ccagggatta
     4441 tgagattcag agagaaagaa tagaacttgg acgctgtatt ggagaaggtc agtttggaga
     4501 tgtacatcaa ggcgtgtacc tgagcccaga gaatccagct ttggctgttg caatcaaaac
     4561 atgtaaaaac tgtacttcgg acagcgtgag agagaagttc cttcaagaag ccttaacaat
     4621 gcgtcagttt gaccatcctc acatcgtgaa gctgattgga gtcattacag agaaccctgt
     4681 ctggataatc atggagttgt gcacacttgg agagctgagg tcatttttgc aagtaagaaa
     4741 atacagcttg gacctggcat ctttgatatt atatgcctat cagcttagta cagcactcgc
     4801 gtatctggag agcaaaagat ttgttcacag ggacattgct gctcggaatg ttctggtgtc
     4861 ttcaaatgat tgtgtaaaat tgggagactt tggattatct cgatatatgg aagacagtac
     4921 ttactataaa gcttccaaag gaaaattacc tattaaatgg atggctccag agtcaatcaa
     4981 ttttcgacgt tttacctcag ctagtgacgt gtggatgttt ggtgtgtgta tgtgggagat
     5041 actgatgcat ggcgtgaagc cttttcaagg agtgaagaac aatgatgtga tcggtcgaat
     5101 tgaaaatggg gaaagattac caatgcctcc aaattgtcct cccaccctct acagccttat
     5161 gacgaaatgt tgggcctatg accccagcag gcggcccagg tttactgaac taaaagctca
     5221 gctcagcaca atcctggagg aggagaaggt gcagcaagaa gaacggatga ggatggaatc
     5281 cagaagacag gctaccgtgt cctgggactc tggagggtct gatgaagcac cacccaagcc
     5341 cagcagacct ggttatccta gcccgagatc cagtgaagga ttttatccca gcccacagca
     5401 catggtccag accaatcact accaggtctc tggctacccg ggttcccatg gaatcccagc
     5461 catggctggc agcatttacc aaggtcaggc atctcttctg gaccagacag aattgtggaa
     5521 tcacagacct caggagatgt ccatgtggca gcccagtgtg gaggattcgg cagctttgga
     5581 ccttcgaggg atgggacagg tgcttccccc tcacctgatg gaagagcggc taatccgaca
     5641 gcagcaggaa atggaagaag accagcgctg gctggagaag gaagagcgat tcctgactgg
     5701 aaaccaacac atctatcagc ctgtggggaa gccagatcct gcagctccac caaagaaacc
     5761 tcctcgccct ggagcacctg gccacctaag caacctgtcc agcatcagca gccctgcaga
     5821 cagctacaat gagggtgtca agccgtggag gcttcagccc caggaaatca gcccccctcc
     5881 cactgccaac cttgaccggt ccaatgacaa ggtatatgaa aatgtgacag gcctagtgaa
     5941 ggctgtcatc gagatgtcca gcaaaatcca gccagctcct ccagaagagt acgtccctat
     6001 ggtgaaggaa gttggcctgg ccctgcggac cttactagcc acggtggatg agaccattcc
     6061 tgctcttcca gccagcactc atcgagagat cgagatggca cagaagctgc tgaactccga
     6121 cttaggcgag ctcatcagca agatgaagct ggcgcagcag tacgtcatga ccagcctgca
     6181 gcaggagtat aagaagcaga tgctgacagc tgctcacgcc ctggctgtgg atgccaagaa
     6241 cctacttgat gttattgatc aagcaagact gaaaatgcta gggcagacac ggccacactg
     6301 agcccctggc cattgaacgt ggctttctgc cctttgggag atcttctcta gcattccacc
     6361 agcagcgagg aagtaacctt agcctctgta gcccgtgctc acggctccaa ctgaatgaca
     6421 gctagctgaa agtctctctt gtataagttt catcacttat acatggtttt gattttgtta
     6481 tttttctaaa tagtgttcag aaaactctgg atccaaaatg tggcattttt ctgagaatga
     6541 agattataca ttaagaagct tttaaaatat acttggtgtt caaattggga tgtgtgttcc
     6601 tagaagtggt aattcatact gaccatgact tcaagttgga agagaaatgt ctgaggaggg
     6661 agggttccct gagaccatgg agactggtta tccttcctgc cagaattcct atccagactg
     6721 tgttgcaata tgctaatctc atttatagag aaagtgcata aaagctatat tttgaagaat
     6781 gagtggtttc aaaagaaaac ttctgccctc cctgtctccg ccttctctcc tgtggatact
     6841 gaagcattgg gttgcgaact atctgtagaa ctgacaaaaa cttgcctttc ctcatcagaa
     6901 ttctgtgcca gttttgtacc agagcactcc caactgcatc aagaaattcc aggaccagcc
     6961 ctgttctcca tttttatata atttataaga ataattaaag ccatgttgac tcttacagcc
     7021 actggagcta actgaccttc attgcgtctg tcttcccagg gaggaccccg caggacaaac
     7081 agggatgtgg ttttctttag atgtccagtt ggtataccat gcattctgtt aggtgatttt
     7141 gagagcatac cttcccttta gtttgttggg ggatataaat tattctcagg aagaatataa
     7201 taaattgtac agttcctctg acctattaaa aaggtggcgc cgggaaa
//
