LOCUS       XM_030248326            7280 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus PTK2 protein tyrosine kinase 2 (Ptk2),
            transcript variant X17, mRNA.
ACCESSION   XM_030248326
VERSION     XM_030248326.2
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000081.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_030248326.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7280
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="15"
     gene            1..7280
                     /gene="Ptk2"
                     /gene_synonym="Fadk; FADK 1; FAK; FRNK; p125FAK"
                     /note="PTK2 protein tyrosine kinase 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 mRNAs, 35 ESTs, 1801 long SRA reads, 11 Proteins,
                     and 86% coverage of the annotated genomic feature by
                     RNAseq alignments, including 16 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:14083"
                     /db_xref="MGI:MGI:95481"
     CDS             3026..6334
                     /gene="Ptk2"
                     /gene_synonym="Fadk; FADK 1; FAK; FRNK; p125FAK"
                     /codon_start=1
                     /product="focal adhesion kinase 1 isoform X12"
                     /protein_id="XP_030104186.1"
                     /db_xref="GeneID:14083"
                     /db_xref="MGI:MGI:95481"
                     /translation="MLLERAGQEALRPTGAVCMEKSGCSPFPVCWAKEYDRYLASSKR
                     MAAAYLDPNLNHTPSSSTKTHLGTGMERSPGAMERVLKVFHYFESSSEPTTWASIIRH
                     GDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHP
                     PEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMQEIADQVDQEIALKLGCL
                     EIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFA
                     NLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNP
                     THLADFNQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYC
                     RLVNGATQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSDEISGDETDDYAEI
                     IDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALAVAIKTCKN
                     CTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKY
                     SLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS
                     TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVI
                     GRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEER
                     MRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYP
                     GSHGIPAMAGSIYQGQASLLDQTELWNHRPQEMSMWQPSVEDSAALDLRGMGQVLPPH
                     LMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSFQGPTGNQHIYQPV
                     GKPDPAAPPKKPPRPGAPGHLSNLSSISSPADSYNEGVKLQPQEISPPPTANLDRSND
                     KVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPALPASTH
                     REIEMAQKLLNSDLGELISKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVI
                     DQARLKMLGQTRPH"
ORIGIN      
        1 tggctcagca tagcctcgct cacaagccta gaggctggca gcttgctgct agggtcccat
       61 gtggcttgct taggaggcca actttcactc ttttgtcagg gttaagaaga aacagctttg
      121 ggtatcctgt gatcagcacc atgtcaccta tgatgtatca ctgtgatcaa agcaaagtat
      181 gagacttgtg cagattcaag gggtgaaaac tcagattctg cctcctgttg ggaggcctgt
      241 caaagactcg gtgacccttt tcagtccact gcagagtgct acctctcctc acaaagccat
      301 ttttgatgca aacccccttt tgtgtcacca ctccaagccc ctccccccta tccttctgat
      361 actttaaata ataatctctc attttacacc atgcaaagct tcattcaccc actcaacaaa
      421 tatttactgt gtgccaggga ctgcctgggg aacaaaacaa agtccctgtt ctatgaatct
      481 agaagtccag agcagagaca atcgagagac ggacaagagc agtgttgaac tgttctgaac
      541 aataggtttg gagacaacag ggtaagcagg caaggagcct agatgggagc acactcagca
      601 gggcaatggg tggctcgggt ttcaaagtag tcagctgaca ttaccgaagt gacaactaac
      661 atggggccga agaaaaagtg ctagaggtga cacagagaca taatcccttc taattttaag
      721 tgcagaaaaa cactataggt tggctattgt gacataatct gtaatcccag caccagaaga
      781 tggaagtaga aagagctgga gttcaaggct atcctcagct acacagaaag ttttagtaca
      841 gcctgggcta catgaaacta tatctcaaac aaacaaacaa acaaacaaga acgaaacaaa
      901 ataaaactag agctagaggg atccctcagt ggttaagagc acttgtcttt ggaaaggtcc
      961 tagattctat tcccacacca acatggtggc tggctcacga ctatctctaa tttcagaaga
     1021 gatccaatac cctcttctga cctccacgtg caccaggcat gtgtgtgata cccatatata
     1081 cattcaagga aaacacacaa gtacaataaa ataaataaat ctgggagaga aaaaaaaacc
     1141 cccaaacata accaccacta ctagttcaaa tccaagttta atacacttca ttaaaaaaaa
     1201 caataaaaaa gaaacactaa aatatggcaa aatctcgaca actcaaagcg ttttattata
     1261 cctgagtaaa ttacagctcc caggtatgta gtggttggtg gttctgtgtt cacctttcac
     1321 tgcctgtcct gcttgctcgt tggcttgtgg tcgaagatca aaatgacacc attaaaaatg
     1381 aaagttcccc gcttctggtt tcatttccta ccgcaaggat gccagtgatt tttttccttt
     1441 ttttttttca gagatcacaa atcagtcacc acttcctgct taagactctc cgtagggttg
     1501 ctgcacaaaa acaaactcag ggaaactagg cacggctcgg aaggacaggg ccacctgctt
     1561 gattcaggca aaggtgtccc cccagtctca cgtttcgtgg taagttccgc gctggaactg
     1621 gctcttaagc cagcagccat ccacagtggc tctcccgttc tggccctcct gtccacccag
     1681 tgtccccgaa aggcttcccc agtcttaaga tctacagggg ctgcgggaag gggctggaat
     1741 gtgagtggcc ccaggcactc ctaaacgatc tttcggaccg tcttcagaga tccattaaaa
     1801 tactctctgt gcctcagttt ccccatctac agaaagccca tgaacctcta ttgaagcggt
     1861 gaagcctgga gaagatcagg gccggcgtgt gtgcggctaa ggatctcctg tgaccgtgag
     1921 ggacccaggc ctagtccgca gaccctgggg cggccacagg ggccacctcg tcatcccgga
     1981 acagcgctat ccgcggacga cgccacgccc gcacagctgg gatacacttt actaggagcc
     2041 gggcgcgccg gactgctctg cgcaggcgcg gtccgcactg cgcaggcgta gagctctgcg
     2101 ctgaggtgag gcattgcgcg ccgcgaggtg tgggcgcgcg ctccccagcc acggcgcacg
     2161 cgcgggcccg cgccgactca gcacggcccg agggcgcgag cccgccgtca ccgctaccgc
     2221 cgccggccgg accgccgtgc gcccggcgtg cgcgtgggag agagcacggc tgccggtgcc
     2281 ggcgccgccc cgctgccttc tatctgcctc agcctcgcgc gcccagtggt ggccggtctc
     2341 tgggctacaa tgtaaagagg aaacagatac taggaatatt ttttagaaca gctatttgat
     2401 ttcttctcaa agtcactgct gccttctgag ttttcctctt gctcctgtga gtaaggggag
     2461 gaatctgttc tatgtctgcc tgtgccagat gtgagagctc tgtgtcatct gtggtatcat
     2521 gcctgtttga cccaagacaa ggtctcacta tgaagcactg actgacctgg aacttgttat
     2581 gtagactagg ctggtttata acccaagaga tcttcctgac cacgcctagg aatgaagttt
     2641 ttaaattctt gtcataaagt agttagcgcc ttctccagct tcctgcagca tgacagaaga
     2701 gagatacagc agttgtttca aagctggcag ggaggtgaac agtggtccta ccagcacttt
     2761 tgggagattg ttgtactagg aagctgcttg tttgttgtct ttgctttcag aagattgcgg
     2821 aagcagaaga ttcagtaact gagaggccac cgtggagctg ctggaaactg ttacagaagg
     2881 agcacctctc aaaccgtgct tcaggctctg agaaaaggag cacaggggaa attagtcttg
     2941 ctttggatcc aagcaaatgc tgtcggagca atgaactggg actttgtgtg cggactcctg
     3001 gcttgatctt gataggattg ggtgtatgtt gttggaacgg gcaggccaag aggccctgag
     3061 acctacaggt gccgtctgta tggagaaaag cggctgtagt ccatttccag tgtgttgggc
     3121 taaagaatat gacagatacc tagcatctag caaaagaatg gcagctgctt atcttgaccc
     3181 aaacttgaat cacacaccaa gttcgagtac taagactcac ctgggtactg gcatggaacg
     3241 gtcccctggt gcaatggaac gagtattaaa ggtctttcat tattttgaaa gcagtagtga
     3301 gccaaccacc tgggccagta ttatcaggca tggagatgct actgatgtca ggggcatcat
     3361 tcagaagata gtggacagtc acaaagtaaa gcacgtggcc tgctatggat ttcgcctcag
     3421 tcacctgcga tcggaggagg tgcactggct gcacgtggac atgggtgtct ccagtgtgag
     3481 ggagaaatat gaactcgccc acccaccaga ggagtggaaa tatgagttga gaattcgtta
     3541 cttgccaaaa ggatttctaa accagtttac tgaagataag ccaacattga atttcttcta
     3601 tcaacaggtg aagagtgact acatgcaaga aatagctgat caagtagacc aagaaatagc
     3661 tttgaagttg ggttgtttgg aaattaggcg atcctattgg gagatgaggg gtaatgccct
     3721 agagaagaag tccaactatg aagtattaga aaaagatgtt ggtttaaagc gattttttcc
     3781 taagagttta ctggattctg tcaaggccaa aacactaaga aagctgatcc agcaaacatt
     3841 caggcagttt gccaacctta atagagaaga aagcatcctg aaattctttg agattctttc
     3901 tcctgtgtac agatttgaca aagagtgctt caagtgtgcc cttgggtcaa gttggatcat
     3961 ttctgtggaa ttggcaatcg gcccagaaga agggatcagt tacctgacag acaaaggctg
     4021 caatcccaca cacctagcag actttaacca agtgcagacc atccagtact caaacagtga
     4081 agacaaagac aggaaaggaa tgctacaact caaaatcgct ggtgctcctg agcctctgac
     4141 cgtgacggca ccatccctaa ccattgccga gaacatggcc gacctgattg atggatactg
     4201 ccggctggtg aatggagcca cacaatcttt catcatcaga ccccagaaag aaggtgaacg
     4261 ggcgttgcca tcaataccaa agttggccaa cagtgaaaag caaggcatgc ggacacatgc
     4321 agtctctgtg tcagatgaaa ttagtgggga cgagacagat gactatgcag agatcatcga
     4381 tgaggaagac acatacacca tgccctcgac cagggattat gagattcaga gagaaagaat
     4441 agaacttgga cgctgtattg gagaaggtca gtttggagat gtacatcaag gcgtgtacct
     4501 gagcccagag aatccagctt tggctgttgc aatcaaaaca tgtaaaaact gtacttcgga
     4561 cagcgtgaga gagaagttcc ttcaagaagc cttaacaatg cgtcagtttg accatcctca
     4621 catcgtgaag ctgattggag tcattacaga gaaccctgtc tggataatca tggagttgtg
     4681 cacacttgga gagctgaggt catttttgca agtaagaaaa tacagcttgg acctggcatc
     4741 tttgatatta tatgcctatc agcttagtac agcactcgcg tatctggaga gcaaaagatt
     4801 tgttcacagg gacattgctg ctcggaatgt tctggtgtct tcaaatgatt gtgtaaaatt
     4861 gggagacttt ggattatctc gatatatgga agacagtact tactataaag cttccaaagg
     4921 aaaattacct attaaatgga tggctccaga gtcaatcaat tttcgacgtt ttacctcagc
     4981 tagtgacgtg tggatgtttg gtgtgtgtat gtgggagata ctgatgcatg gcgtgaagcc
     5041 ttttcaagga gtgaagaaca atgatgtgat cggtcgaatt gaaaatgggg aaagattacc
     5101 aatgcctcca aattgtcctc ccaccctcta cagccttatg acgaaatgtt gggcctatga
     5161 ccccagcagg cggcccaggt ttactgaact aaaagctcag ctcagcacaa tcctggagga
     5221 ggagaaggtg cagcaagaag aacggatgag gatggaatcc agaagacagg ctaccgtgtc
     5281 ctgggactct ggagggtctg atgaagcacc acccaagccc agcagacctg gttatcctag
     5341 cccgagatcc agtgaaggat tttatcccag cccacagcac atggtccaga ccaatcacta
     5401 ccaggtctct ggctacccgg gttcccatgg aatcccagcc atggctggca gcatttacca
     5461 aggtcaggca tctcttctgg accagacaga attgtggaat cacagacctc aggagatgtc
     5521 catgtggcag cccagtgtgg aggattcggc agctttggac cttcgaggga tgggacaggt
     5581 gcttccccct cacctgatgg aagagcggct aatccgacag cagcaggaaa tggaagaaga
     5641 ccagcgctgg ctggagaagg aagagcgatt cctgaaacct gatgtgaggc tctctcgagg
     5701 cagcatcgac agggaagacg ggagttttca gggtccgact ggaaaccaac acatctatca
     5761 gcctgtgggg aagccagatc ctgcagctcc accaaagaaa cctcctcgcc ctggagcacc
     5821 tggccaccta agcaacctgt ccagcatcag cagccctgca gacagctaca atgagggtgt
     5881 caagcttcag ccccaggaaa tcagcccccc tcccactgcc aaccttgacc ggtccaatga
     5941 caaggtatat gaaaatgtga caggcctagt gaaggctgtc atcgagatgt ccagcaaaat
     6001 ccagccagct cctccagaag agtacgtccc tatggtgaag gaagttggcc tggccctgcg
     6061 gaccttacta gccacggtgg atgagaccat tcctgctctt ccagccagca ctcatcgaga
     6121 gatcgagatg gcacagaagc tgctgaactc cgacttaggc gagctcatca gcaagatgaa
     6181 gctggcgcag cagtacgtca tgaccagcct gcagcaggag tataagaagc agatgctgac
     6241 agctgctcac gccctggctg tggatgccaa gaacctactt gatgttattg atcaagcaag
     6301 actgaaaatg ctagggcaga cacggccaca ctgagcccct ggccattgaa cgtggctttc
     6361 tgccctttgg gagatcttct ctagcattcc accagcagcg aggaagtaac cttagcctct
     6421 gtagcccgtg ctcacggctc caactgaatg acagctagct gaaagtctct cttgtataag
     6481 tttcatcact tatacatggt tttgattttg ttatttttct aaatagtgtt cagaaaactc
     6541 tggatccaaa atgtggcatt tttctgagaa tgaagattat acattaagaa gcttttaaaa
     6601 tatacttggt gttcaaattg ggatgtgtgt tcctagaagt ggtaattcat actgaccatg
     6661 acttcaagtt ggaagagaaa tgtctgagga gggagggttc cctgagacca tggagactgg
     6721 ttatccttcc tgccagaatt cctatccaga ctgtgttgca atatgctaat ctcatttata
     6781 gagaaagtgc ataaaagcta tattttgaag aatgagtggt ttcaaaagaa aacttctgcc
     6841 ctccctgtct ccgccttctc tcctgtggat actgaagcat tgggttgcga actatctgta
     6901 gaactgacaa aaacttgcct ttcctcatca gaattctgtg ccagttttgt accagagcac
     6961 tcccaactgc atcaagaaat tccaggacca gccctgttct ccatttttat ataatttata
     7021 agaataatta aagccatgtt gactcttaca gccactggag ctaactgacc ttcattgcgt
     7081 ctgtcttccc agggaggacc ccgcaggaca aacagggatg tggttttctt tagatgtcca
     7141 gttggtatac catgcattct gttaggtgat tttgagagca taccttccct ttagtttgtt
     7201 gggggatata aattattctc aggaagaata taataaattg tacagttcct ctgacctatt
     7261 aaaaaggtgg cgccgggaaa
//
